As a leader in the field of integrative care, the Osher Center for Integrative Health at UC is involved in several federally-funded research projects. We are currently investigating mind-body and food-as-medicine interventions.
Research Priorities Include:
Conducting comparative effectiveness studies
Comparing integrative care models to usual care
Examining sustainable models of integrative care
Building academic and community research partnerships
Current Projects
Workplace Mindfulness: 5-week or 8-week virtual programs, one-hour presentations, and half or full-day retreats options, for businesses to support associate wellness focused on building resilience and managing stress. All programs are evaluated with input from the client to address pain points and growth/change after the mindfulness training is implemented. Includes programming through the Universal Provider Grant through the University of Cincinnati Provost’s Office and programming with clients such as P&G, Cincinnati Regional Chamber of Commerce, Cincinnati Bar Association, Kilgour Elementary School, and Withrow High School.
Alternatives to opioids for pain in the emergency department: Implementing Integrative Health approaches and expanding local nerve block initiatives: In partnership with Emergency Medicine, this SAMHSA-funded grant will expand the use of available evidence-based options for pain management in the emergency department (ED), focusing on pain relief and empowering people with tools to use for pain management while minimizing the risk of potential harms from opioid exposure. A full menu of integrative health and medicine techniques will be introduced and available for novel outpatient follow-up (e.g., acupuncture, yoga), with patients receiving information on mindfulness and stress reduction techniques to use immediately. Mindfulness and resilience training sessions will be offered to ED prescribers in an effort to decrease personal burnout through experiencing the benefits of this mind-body modality firsthand and allowing them to be more informed when offering these interventions to patients.
Practice-Based Integrative Health Research: To promote wellness through the prevention and treatment of various diseases with lifestyle and behavioral approaches including nutrition, physical activity, stress reduction and connectivity, and evidence-based integrative therapies. All integrative health clinical programs are evaluated for feasibility, acceptability, and preliminary effectiveness using a practice-based research approach. Types of patients mostly seen are patients with multiple sclerosis, Parkinson's disease, diverse types of cancer, including blood cancer and chronic pain. This is an evaluation research project to measure the effects of the different Integrative Medicine (IM) therapies on stress, diet, sleep and social functioning.
To evaluate the use of Integrative/Lifestyle Medicine (IM/LM) therapies prescribed to patients seen at IM/LM clinic at the UC, including Nature Rx.
Effectiveness and patient utilization of services at the UC Osher Center for Integrative Medicine, including Massage therapy at the UC Blood Cancer Healing Center
To evaluate the health impact of lifestyle and Integrative Medicine (IM) modalities offered via group medical visits (GMVs) and individual patient encounters seen at the IM clinics.
Mind-Body Skills Program: 9-week 2-hours/week experiential course that provides students, faculty, and staff with self-care and reflection skills combined with group support to adaptively deal with stressors and build resilience. Faculty and staff facilitators are trained to lead groups during a 3-day immersive, experiential retreat. This course has trained faculty/staff in the Colleges of Medicine, Nursing, Pharmacy, Allied Health, Law, DAAP, CCM, CECH, Arts & Sciences, Blue Ash, and CCHMC. Mixed method data collected pre-post 9 week program and at one-year follow-up.
Novak, B. K., Gebhardt, A., Pallerla, H., McDonald, S.B., Haramati, A., & Cotton, S. (2020). Impact of a university-wide interdisciplinary mind-body skills program on student mental and emotional well-being. Global Advances in Health and Medicine. https://doi.org/10.1177/2164956120973983
Mindful Stress Reduction at the Free Store Food Bank Cincinnati COOKS! Program: 6-week group stress reduction program modified from the evidence-based Mindfulness Based Stress Reduction program developed by Dr. Jon Kabat Zinn. This program has been piloted at Cincinnati COOKS!, a second-chance job training program offered through the Free Store Food Bank. Mixed method data collected pre-post each program series.
College of Medicine Student Wellness Assessment: annual assessment of all College of Medicine medical students to develop and test a cross-institutional standard evaluation for student emotional and mental well-being. Currently we are on year 4 of longitudinal cohort data collection.
Build it Bites: BUILD-IT-BITES workshops created at Cincinnati Children’s by Dr Carina Braeutigam combines hands on teaching kitchen practices with mindfulness to avoid overall malnutrition and create positive culinary experiences for young children/adolescents with cancer and their families. Post-intervention mixed-method evaluations are collected.
Parkinson’s wellness program: To promote wellness through the prevention and treatment of Parkinson’s disease with lifestyle and behavioral approaches including nutrition, physical activity, stress reduction and connectivity, and evidence-based integrative therapies. All integrative health clinical programs are evaluated for feasibility, acceptability, and preliminary effectiveness using a practice-based research approach.
Creating Caring Communities: 7-week 1-hour/week program that provides students, faculty, and staff with group support and encourages self-care and wellness. This program is designed to create an environment to connect in a safe, authentic setting that allows participants to speak freely about how they are adjusting professionally and personally in these virtual times and to share challenges, joys, and to be there for each other.
Practice-Based Integrative Health Research: To promote wellness through the prevention and treatment of various diseases with lifestyle and behavioral approaches including nutrition, physical activity, stress reduction and connectivity, and evidence-based integrative therapies. All integrative health clinical programs are evaluated for feasibility, acceptability, and preliminary effectiveness using a practice-based research approach.
Integrative Medicine Modality Usage and Impact on Patients with Chronic Pain Conditions in an Urban Clinic Setting.
Efficacy of Integrative Medicine Therapies on Chronic Headache Severity: A Retrospective Study.
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Integrative Medicine Publications and Posters/Presentations
Yang J, Lei D, Suo X, Tallman MJ, Qin K, Li W, Bruns KM, Blom TJ, Duran LRP, Cotton S., Sweeney JA, Gong Q, DelBello MP (2021 Nov). A preliminary study of the effects of mindfulness-based cognitive therapy on structural brain networks in mood-dysregulated youth with a familial risk of bipolar disorder. Early Interv Psychiatry. Online ahead of print.
Qin K, Lei D, Yang J, Li W, Tallman MJ, Duran LRP, Blom TJ, Bruns KM, Cotton S., Sweeney JA, Gong Q, DelBello MP. (2021 Apr). Network-level functional typological changes after mindfulness-based cognitive therapy in mood dysregulated adolescents at familial risk for bipolar disorder: a pilot study. BMC Psychiatry. 28;21(1):213.
Novak BK, Gebhardt A, Pallerla H, McDonald SB, Haramati A, Cotton S.* (2020). Impact of a University-Wide Mind-Body Skills Program on Student Mental and Emotional Well-being, Glob Adv Health Med (9).
Wasson RS, Luberto CM, Murthi M, McDonald SB, Pallerla H, Novak BK, Cotton S.* (2020). Feasibility and acceptability of a community-based modified mindfulness-based stress reduction program for the under-resourced and unemployed. Glob Adv Health Med. Nov 8; 9:2164956120973636.
Hente, E., Sears, R., Siracusa, C., Filigno, S., Cotton, S., Pallerla, H., & Boat, T. (2020). A Pilot Study of Mindfulness-Based Cognitive Therapy to Improve Well-Being for Health Professionals Providing Chronic Disease Care, J Pediatr, Sept; 224:87-93.
Luberto, C.M., Hall, D.L, Park, E.R., Haramati, A., Cotton, S.* (2020). A Perspective on the Similarities and Differences Between Mindfulness and Relaxation. Glob Adv Health Med, (9): 1-13.
MacVittie, K, Beucler, A, McGraw, M, Pallerla, H, Shewakramani, S, Freiermuth, C, Cotton, S. Impact of a Brief, Tailored Eight-Week Mindfulness Intervention for Emergency Department Personnel. Poster accepted for presentation at the International Congress on Integrative Medicine & Health; 2025; Seattle, WA, USA.
Trichy, N., Dillman, O., Pallerla, H., Funke, C., Cotton, S & Golubic, M. Efficacy of Integrative Medicine on Chronic Headache Severity: A Retrospective Study. Poster presentation at the 2024 International Congress on Integrative Medicine and Health, April 2024, Cleveland OH.
Olulayole Adedeji, Conner Funke, Harini Pallerla, Mladen Golubic, Integrative Medicine Modality Usage and Impact on Patients with Chronic Pain Conditions in an Urban Clinic Setting presented at: 2023 Integrative Medicine and Health Symposium in Chicago, Illinois, USA (February 28 – March 2, 2023)
Conner D Funke, Harini Pallerla, Olulayole O Adedeji, Mladen Golubic A Retrospective Chart Review of Integrative Medicine Treatments for Patients with Chronic Headaches at an Urban Clinic poster presentation 2023 Integrative Medicine and Health Symposium in Chicago, Illinois, USA (February 28 – March 2, 2023)
Funke, C., McGraw, M., McDonald, S., Pallerla, H & Cotton, S.* “Impact of an 8-Week Mindfulness and Resilience Virtual Training on Stress and Burnout for University Faculty and Staff” poster presentation at the 2022 International Congress on Integrative Medicine and Health in Phoenix, Arizona, USA on May 23-26, 2022.
Doshi, S., Klafter, S., Pallerla, H., McDonald, S., Malosh, L & Cotton, S*. “The Relationships Among Race, Gender, and Resiliency in Medical Students: A Longitudinal Analysis” oral presentation at the 2022 International Congress on Integrative Medicine and Health in Phoenix, Arizona, USA on May 23-26, 2022. Travel award student first author.
Klatt, M., Steinberg, B., Colombini, L., Habash, D., Cotton, S., Fontaine, K., Lyle, K. “Moving Integrative Medicine towards INTEGRATED Medicine in Two Large Academic Medical Centers” oral symposium accepted for presentation at the International Congress on Integrative Medicine and Health in Cleveland, Ohio, USA on April 28-May 1, 2020
Hancock, J., D’Amico, C., Pallerla, H., Novak, B., Espay, A., Stecher, B., & Cotton, S.* (2020). “Developing an Integrative Health and Wellness Program for Parkinson’s Disease Patients.” Glob Adv Health Med, 9: 11.
Novak, B., Lyle, K., Pallerla, H., Moss, E., Sacco, J., & Cotton, S.* (2020). “A Short and Long-Term Evaluation of a University-Wide Interdisciplinary Mind-Body Skills Program” Glob Adv Health Med, 9: 101.
Novak, B., Lyle, K., Pallerla, H., Moss, E., Sacco, J., & Cotton, S.* (2020). “The Development and Evaluation of an Undergraduate Integrative Health Certificate Program” Glob Adv Health Med, 9: 124.
Harini is a Principal Research Associate with the Department of Family and Community Medicine at the University of Cincinnati. Harini has a Master’s degree in Health Administration & Planning from the University of Cincinnati with a primary focus on Health Services Research. Her specialization is in quantitative research methods, data analysis, database design, and application support. She has over ten years of experience in managing research projects and assists UC faculty, residents, and medical students with their research.
Sian Cotton, PhD, founding director of the Osher Center for Integrative Health and the Turner Farm Foundation Chair at the University of Cincinnati College of Medicine, is a licensed clinical psychologist. A Professor in the Department of Family and Community Medicine and Division Director for Integrative Medicine, Dr. Cotton has an active research lab with ongoing clinical studies focusing primarily on mindfulness-based interventions and integrative medicine practice-based research. She is currently the Chair of the Board of Directors for the Academic Consortium of Integrative Medicine and Health, a group of over 85 leading academic health centers, and served as 1 of 8 Congress Co-Presidents for the 2nd World Congress on Integrative Medicine in Rome, September 2023. Dr. Cotton is often invited to speak with community organizations and businesses, healthcare audiences, and academics about mind-body medicine for stress reduction, and preventive and wellness-based approaches to healthcare.
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MSSP & Summer Student Research Program
Students will learn mixed-methods program evaluation and clinical research skills through the Osher Center for Integrative Health in lifestyle medicine outpatient clinics, the UC Cancer Wellness Clinic, lifestyle medicine group visits, and Workplace Mindfulness programs. Typical tasks may include: literature reviews, data collection, building databases, data entry, shadowing data analysis and reporting, building tables/graphs, Microsoft Office and Canva formatting, abstract writing, creating poster presentations, and manuscript writing
Meet Our MSSP in Integrative & Lifestyle Medicine Students
“I believe the human body was built to thrive. Integrative medicine is the future of disease prevention.”
Education and Experience
University of Cincinnati College of Medicine M.D. Candidate | Class of 2028
Bachelors of Science in Neuroscience from Vanderbilt University
Research Assistant at the Osher Center for Integrative Medicine at the Northwestern Feinberg School of Medicine
What do you hope to gain from participating in the Integrative Medicine MSSP Program?
I look forward to learning about all the unique tools that Integrative Medicine has to offer. I want to use these insights as a physician to create comprehensive care plans that empower my patients to proactively manage their health. Ultimately, my vision is to build a healthcare model that emphasizes prevention and whole-person care.
Aadi Pallerla
“I believe that our medical system and our communities can be improved by placing an increased emphasis on the way that cultures and lifestyles impact health.”
Education & Experience
University of Cincinnati College of Medicine MD-MPH Candidate | Class of 2029
Bachelor of Science in Microbiology and Medical Anthropology, Minor in History from The Ohio State University
Student researcher at the Spakowicz Lab at Ohio State University focused on the gut microbiome and diet-based interventions for cancer immunotherapy response
What do you hope to gain from participating in the Integrative Medicine MSSP Program?
Studying medical anthropology, I learned about the importance of understanding the sociocultural side of medicine and its potential to improve patient outcomes without an excessive focus on surgical or pharmacological therapies. I am excited for the opportunity to apply some of the principles I learned and discover how evidence-based diet and lifestyle therapies can make meaningful contributions to the management and prevention of illness.
Marcus Grewal
“Integrative medicine empowers individuals to take charge of their health by emphasizing prevention and promoting lifelong wellness.”
Education & Experience
University of Cincinnati College of Medicine M.D. Candidate | Class of 2028
Bachelors of Science in Biology from Stanford University
Research assistant at the University of Chicago TMW Center for Early Learning, Lifestyle Medicine research intern at Apeiron Life
What do you hope to gain from participating in the Integrative Medicine MSSP Program?
I believe integrative and lifestyle medicine are the multidisciplinary cornerstone of treating chronic disease, and through this program I am excited to explore how this approach can impact patient care. I am eager to learn from a variety of physicians who value preventative medicine, and to develop the skills and tools to apply these techniques into my own career treating patients.
"I believe that integrative and lifestyle medicine are the future of preventing disease and lessening pain."
Education & Experience
University of Cincinnati College of Medicine M.D. Candidate | Class of 2027
Bachelors of Science in Health Sciences from Furman University
Volunteering experience working with community members to develop healthy diet and exercise habits as a FitRx coach
What do you hope to gain from participating in the Integrative Medicine MSSP Program?
I believe that integrative and lifestyle medicine are critical in developing a well-rounded and resourceful physician. In an age where chronic disease, polypharmacy, and reactionary procedures lead to high medical expenditures and adverse outcomes for patients, integrative and lifestyle medicine are extremely relevant.
Katie MacVittie
"I believe healthcare in America needs to shift more to preventative and lifestyle medicine, and I am so excited to be learning more about this approach so early in my medical education"
Education & Experience
University of Cincinnati College of Medicine M.D. Candidate | Class of 2027
Bachelors of Science in Neuroscience from the University of Pennsylvania, Minors in Nutrition Science, Hispanic Studies, and Chemistry
Medical Assistant at AIM for Wellbeing, an Integrative Medicine Clinic in Cincinnati, Volunteer at Hospice of Cincinnati
What do you hope to gain from participating in the Integrative Medicine MSSP Program?
I am excited to see how UC brings lifestyle medicine and modalities such as nutrition or acupuncture to patients with chronic disease and those undergoing cancer treatment. I am passionate about becoming a physician trained in Integrative Medicine and utilizing this holistic approach to improve the lives of my future patients.
Christen Lescallett
“My goal is to learn how to guide patients towards healthy lifestyle improvements that are implementable and change the course of their healthspan”
Education & Experience:
University of Cincinnati College of Medicine M.D. Candidate, Class of 2027
Bachelor of Science in Nutrition from the Ohio State University
Experience as a research assistant studying housing for homeless youth, patient care associate for patients with disabilities, and volunteer at NNEMAP Food Pantry
What do you hope to gain from participating in the Integrative Medicine MSSP program?
I hope to learn more about the field of Integrative Medicine so that I’m more prepared to provide patients with evidence-based options for complementary therapies and lifestyle changes, so that I can provide holistic and preventative care that’s impactful.
"I want to improve the health of the community by educating and making healthy food options more affordable for under-resourced populations and, ultimately, alleviate food insecurities."
Education & Experience
University of Cincinnati College of Medicine M.D. Candidate | Class of 2026
Bachelor of Science in Medical Sciences, Minors/Certificate in Public Health, Nutrition, and Global Health Studies from the University of Cincinnati
She currently serves as a Bearcat Mentor and Lead Teacher at New Leaf Kitchen. She also helped develop the Bearcats Food Recovery Network, a public health program in partnership with the University of Cincinnati, to distribute extra food from campus dining locations to communities in need.
What do you hope to gain from participating in the Integrative Medicine MSSP Program?
I hope to learn about the cultural and historical backgrounds behind integrative therapies and the systemic challenges associated with implementing them. Utilizing this knowledge, I will read, learn, and share existing journals focused on current innovations in Lifestyle Medicine and Integrative Health with my colleagues during journal clubs and interest group meetings. After consolidating this information, I aspire to contribute to research oriented around identifying the health disparities that exist within the community and developing effective avenues to address them.
Megan Knauer
“We must shift medicine to emphasizing prevention and meeting people where they’re at in their journeys. This begins with figuring out what patients can control, and what lifestyle factors are mutable.”
Education & Experience
University of Cincinnati College of Medicine M.D. Candidate | Class of 2026
Bachelor of Sciences in Medical Utilitarianism from Duke University
She also worked as a research assistant and as an intern at Duke University’s healthcare policy center
What do you hope to gain from participating in the Integrative Medicine MSSP Program?
I hope to participate in the integrative medicine MSSP because I want to understand how to incorporate stress management, dietary changes, and every other aspect of holistic care into my practice. Further, I want to make this model of care possible for every patient. Further, I want to make this model of care possible for every patient. I hope that participating in this MSSP program will expose me to the different tools that integrative medicine incorporates, will allow me to make connections with leaders in the field so I can discover where I can be useful in expanding this model, and will teach me to connect with patients in a way that sees each as their story, not as their diagnoses.
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Resources
Faculty Scholarly Activity: For individual affiliated faculty research areas, priorities and activity, please visit our Directory Page and click on the faculty member for research information.