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MS Program Research Interests

Mentor & Department*		Research Interests
Zalfa Abdel-Malek, PhD Department of Dermatology		Regulation of human pigmentation, photobiology and photocarcinogenesis, genetic susceptibility to melanoma; role of melanocortins and the melanocortin 1 receptor
Hassane Amlal,PhD Internal Medicine Nephrology		Regulation of acid-base transporters, glutamine metabolism, and inorganic phosphate in health and disease
Mark Baccei,PhD Department of Anesthesiology		Characterization of the short- and long-term consequences of tissue injury during early life for the function of developing synaptic networks in the superficial dorsal horn of the spinal cord
George Deepe, MD Department of Internal Medicine Division of Infectious Diseases		Cellular immunology of fungal infections; characterization of the protective T-cell epitopes of H. capsulatum antigens and analysis of the functional activity of antigen-reactive T-cells
Senad Divanovic, PhD Cincinnati Children's Division of Immunobiology		Our research program focuses on the role of immune response in inflammation and metabolism. Our expertise in pathways that regulate innate immunity — developed through the pursuit of studies ranging from reductive analysis of TLR ligand signaling to the role of IL-17 axis in experimental models of obesity and infection — have spearheaded the projects aimed at defining the role of the immune mediators in the development and progression of obesity, obesity-associated sequelae and infection / inflammation driven preterm birth.
Christy Holland, PhD UC Internal Medicine Division of Cardiovascular Diseases		Bioeffects of Diagnostic and Therapeutic Ultrasound, Acoustic Cavitation, New Diagnostic imaging Techniques for the Early Detection of Vascular Disease and Ischemic Injury to Brain
David Hui, PhD Department of Pathology and Laboratory Medicine		Lipid Metabolism, Atherosclerosis, Diabetes, Obesity, Vascular Biology Our research program focuses on three specific areas relating cholesterol metabolism with individual susceptibility for coronary heart disease.
Jeffrey Molkentin, PhD Cincinnati Children's Division of Molecular Cardiovascular Biology		Molecular biology of heart and skeletal muscle disease
Joseph Qualls,PhD Cincinnati Children's Division of Infectious Diseases		Immunology; innate immunity; macrophage biology; amino acid metabolism; intracellular pathogenesis
Jack Rubinstein, MD Department of Internal Medicine Division of Cardiology		Advanced Echocardiographic Imaging, Myocardial Energy Utilization
Laura Ramsey, PhD Cincinnati Children's Research in Patient Services		The Ramsey lab is interested in all aspects of pharmacogenetics, from basic research to implementation in patient care. Pharmacogenetics refers to the effect of a person’s genetic code on his/her response to a medication. Research has been done in this field for decades, but only recently has pharmacogenetic information been incorporated into clinical care. There are now guidelines for dosing of more than 30 drugs based on genetic information, provided by the NIH-funded Clinical Pharmacogenetics Implementation Consortium (CPIC). Many of the genes involved in response to medication alter the pharmacokinetics of the drug (the speed at which it’s absorbed, distributed, metabolized or eliminated).
Sakthivel Sadayappan, PhD, MBA Department of Internal Medicine Division of Cardiology		The long-term goal of the Sadayappan Lab involves 1) elucidating the causes of muscle-specific diseases at the molecular level and 2) identifying therapeutic targets that will lead to the development of effective cures. The more specific objectives involve determining the up- and downstream regulators of sarcomere structure and function of both cardiac and skeletal muscles in health and disease. The sarcomere is the functional unit of striated muscle to generate contractility.
Manoocher Soleimani, MD Department of Internal Medicine Division of Cardiology		Identification, Cloning and Examination of Genes Regulating Acid Base Transport in the Kidney, Salt Absorption in the Kidney Distal Nephron and Blood Pressure Regulation Through the Generation and Examination of Transgenic Mice, Identification and Examination of Genes that Play Important Roles in Either Promoting or Protecting Against Tissue Injury in Kidney Damage
Saulius Sumanas, PhD Cincinnati Children's Division of Developmental Biology		Blood vessel formation is tightly linked to different types of vascular diseases, wound healing, regeneration and cancer in humans. Mechanisms controlling blood vessel formation de novo, vasculogenesis, and blood vessels sprouting from the existing vessels, angiogenesis, are still poorly understood.
Tom Thompson, PhD Department of Molecular Genetics		Study of the structural and functional aspects of TGFbeta family signaling and regulation along with the structures of apolipoproteins and how this relates to HDL particles and other related biological functions. The laboratory uses a combination of structural techniques including X-ray crstallography, small angle X-ray scattering coupled with biophysical and biochemical experiments.
Michael Tranter, PhD Department of Internal Medicine Division of Cardiology		The long-term goals of my research are to increase our understanding of the molecular mechanisms of cardiovascular disease. Within this realm, the ongoing work in the laboratory is broadly centered around post-transcriptional gene regulation in the setting of (1) pathological left ventricular hypertrophy and fibrosis, and (2) the mechanisms of cardioprotection against ischemia/reperfusion injury.
Patrick Tso, PhD Department of Pathology and Laboratory Medicine		One of our research goals is to gain a better understanding of the mechanisms and factors regulating intestinal lipid absorption and the assembly and secretion of chylomicrons and very low density lipoproteins by the small intestine. The techniques we employ consist of conscious intestinal lymph fistula rats, lymph fistula mouse, intestinal epithelial cell culture, and also molecular biology.
Yi-Gang Wang, PhD Department of Pathology and Laboratory Medicine		Currently, Dr. Wang's research activities focus on stem cell therapies using three animal models. These models are myocardial infarction (MI) via ligation of the left anterior descending (LAD) coronary artery, heterotopic heart transplantation, and the use of a special cell patch to treat MI. These models are used to explore the role of progenitor cell differentiation, migration, and proliferation on protection and functional regeneration of injured heart tissue.
Joshua Waxman, PhD Cincinnati Children's Division of Molecular Cardiovascular Biology		The Waxman Lab uses genetic, molecular and cellular biological techniques to understand the underlying mechanisms of congenital heart defects and cardiomyocyte formation during development.
Jun-Ming Zhang, MD Department of Anesthesiology		Physiology and pathophysiology of neuropathic pain, Sympathetic regulation of inflammatory response in pain, Mechanisms and management of low back pain, Sodium channels, ectopic discharges and pathological pain. Specifically, we are interested in whether extended nerve block provides additional benefit for patients with traumatic injury in lowing the risk of chronic pain; and how to improve efficacy of epidural steroids for managing low back pain.
*Please check rotation availability with your advisor

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Pharmacology & Physiology (MS) Programs

University of Cincinnati
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Cincinnati, OH 45267-0576

Dr. Katie Hobbing

Medical Sciences Building
Office 4203
Phone: 513-558-4159
Email: katie.hobbing@uc.edu