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Du Laboratory



Che, Lixiao; Alavattam, Kris G; Stambrook, Peter J; Namekawa, Satoshi H; Du, Chunying 2020. BRUCE preserves genomic stability in the male germline of mice. Cell death and differentiation, ,


Che, Lixiao; Yang, Xingyuan; Ge, Chunmin; El-Amouri, Salim S; Wang, Qi-En; Pan, Dao; Herzog, Thomas J; Du, Chunying 2019. Loss of BRUCE reduces cellular energy level and induces autophagy by driving activation of the AMPK-ULK1 autophagic initiating axis. PloS one, 14 5, e0216553

Ge, Chunmin; Vilfranc, Chrystelle L; Che, Lixiao; Pandita, Raj K; Hambarde, Shashank; Andreassen, Paul R; Niu, Liang; Olowokure, Olugbenga; Shah, Shimul; Waltz, Susan E; Zou, Lee; Wang, Jiang; Pandita, Tej K; Du, Chunying 2019. The BRUCE-ATR signaling axis is required for accurate DNA replication and suppression of liver cancer development. Hepatology (Baltimore, Md.), ,


Lin, Yu-Fen; Shih, Hung-Ying; Shang, Zeng-Fu; Kuo, Ching-Te; Guo, Jiaming; Du, Chunying; Lee, Hsinyu; Chen, Benjamin P C 2018. PIDD mediates the association of DNA-PKcs and ATR at stalled replication forks to facilitate the ATR signaling pathway. Nucleic acids research, 46 4, 1847-1859


Pan, Ji-An; Sun, Yu; Jiang, Ya-Ping; Bott, Alex J; Jaber, Nadia; Dou, Zhixun; Yang, Bin; Chen, Juei-Suei; Catanzaro, Joseph M; Du, Chunying; Ding, Wen-Xing; Diaz-Meco, Maria T; Moscat, Jorge; Ozato, Keiko; Lin, Richard Z; Zong, Wei-Xing 2016. TRIM21 Ubiquitylates SQSTM1/p62 and Suppresses Protein Sequestration to Regulate Redox Homeostasis. Molecular cell, 62 1, 149-151

Contact Us

Department of
Cancer Biology

Vontz Center for Molecular Studies
3125 Eden Avenue
PO Box 670521
Cincinnati, OH 45267-0521

Mail Location: 0521
Phone: 513-558-5323
Fax: 513-558-1190