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Our lab investigates the mechanistic biology of carcinogenesis in renal cancer and develops prognostic tools that indicate kidney cancer cases that require aggressive therapy. Discovery of mechanistic biology and delivery of prognostic tools enables holistic care for kidney cancer that balances quality of life and cutting-edge therapy for patients and their loved ones.
We focus on the most common type of renal cancer, clear cell renal cell carcinoma (ccRCC). Histologically defined ccRCC is not a uniform disease, and different genetic, molecular and metabolic subtypes are described carrying various therapeutic vulnerabilities with consequences for personalized medicine.
We work on two main fields of research:
Vontz Center for Molecular Studies 3125 Eden AvenuePO Box 670521Cincinnati, OH 45267-0521
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