Cancer Biology Publications

 

2023

Hunt, Brian G; Fox, Levi H; Davis, James C; Jones, Angelle; Lu, Zhixin; Waltz, Susan E 2023. An Introduction and Overview of RON Receptor Tyrosine Kinase Signaling. Genes, 14 2,

Ren, Lu; Du, Wa; Song, Dan; Lu, Haocheng; Hamblin, Milton H; Wang, Chenran; Du, Chunying; Fan, Guo-Chang; Becker, Richard C; Fan, Yanbo 2023. Genetic ablation of diabetes-associated gene Ccdc92 reduces obesity and insulin resistance in mice. iScience, 26 1, 105769

Fang, Hongbao; Hu, Lianting; Chen, Qixin; Geng, Shanshan; Qiu, Kangqiang; Wang, Chengjun; Hao, Mingang; Tian, Zhiqi; Chen, Huimin; Liu, Lei; Guan, Jun-Lin; Chen, Yuncong; Dong, Lei; Guo, Zijian; He, Weijiang; Diao, Jiajie 2023. An ER-targeted "reserve-release" fluorogen for topological quantification of reticulophagy. Biomaterials, 292 , 121929

2022

Ruiz-Torres, Sasha J; Bourn, Jennifer R; Benight, Nancy M; Hunt, Brian G; Lester, Carissa; Waltz, Susan E 2022. Macrophage-mediated RON signaling supports breast cancer growth and progression through modulation of IL-35. Oncogene, 41(3) Jan, 321-333

Hunt, Brian G; Jones, Angelle; Lester, Carissa; Davis, James C; Benight, Nancy M; Waltz, Susan E 2022. RON (MST1R) and HGFL (MST1) Co-Overexpression Supports Breast Tumorigenesis through Autocrine and Paracrine Cellular Crosstalk. Cancers, 14 10,

Brown, Nicholas E; Jones, Angelle; Hunt, Brian G; Waltz, Susan E 2022. Prostate tumor RON receptor signaling mediates macrophage recruitment to drive androgen deprivation therapy resistance through Gas6-mediated Axl and RON signaling. The Prostate, ,

Vicente-Muñoz, Sara; Hunt, Brian G; Lange, Taylor E; Wells, Susanne I; Waltz, Susan E 2022. NMR-based metabolomic analysis identifies RON-DEK-?-catenin dependent metabolic pathways and a gene signature that stratifies breast cancer patient survival. PloS one, 17 9, e0274128

Blaha, Catherine S; Ramakrishnan, Gopalakrishnan; Jeon, Sang-Min; Nogueira, Veronique; Rho, Hyunsoo; Kang, Soeun; Bhaskar, Prashanth; Terry, Alexander R; Aissa, Alexandre F; Frolov, Maxim V; Patra, Krushna C; Brooks Robey, R; Hay, Nissim 2022. A non-catalytic scaffolding activity of hexokinase 2 contributes to EMT and metastasis. Nature communications, 13 1, 899

Li, Qianqian; Li, Yutian; Huang, Wei; Wang, Xiaohong; Liu, Zhenling; Chen, Jing; Fan, Yanbo; Peng, Tianqing; Sadayappan, Sakthivel; Wang, Yigang; Fan, Guo-Chang 2022. Loss of Lipocalin 10 Exacerbates Diabetes-Induced Cardiomyopathy via Disruption of Nr4a1-Mediated Anti-Inflammatory Response in Macrophages. Frontiers in immunology, 13 , 930397

Qiu, Kangqiang; Seino, Ryo; Han, Guanqun; Ishiyama, Munetaka; Ueno, Yuichiro; Tian, Zhiqi; Sun, Yujie; Diao, Jiajie 2022. De novo Design of A Membrane-anchored Probe for Multi-dimensional Quantification of Endocytic Dynamics. Advanced healthcare materials, , e2102185

Shannon, Daniel; Gruber, Weston; Lohmueller, Isaac; Hawryschuk, Ethan; Medley, Wyatt; Poetker, Gavin; Diao, JaiJie 2022. The role of FIP200 in Phagophore formation during Autophagy. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 36 Suppl 1 ,

Wang, Lei; Diao, Jiajie 2022. VAMP8 phosphorylation regulates lysosome dynamics during autophagy. Autophagy reports, 1 1, 79-82

Muto, Tomoya; Guillamot, Maria; Yeung, Jennifer; Fang, Jing; Bennett, Joshua; Nadorp, Bettina; Lasry, Audrey; Redondo, Luna Zea; Choi, Kwangmin; Gong, Yixiao; Walker, Callum S; Hueneman, Kathleen; Bolanos, Lyndsey C; Barreyro, Laura; Lee, Lynn H; Greis, Kenneth D; Vasyliev, Nikita; Khodadadi-Jamayran, Alireza; Nudler, Evgeny; Lujambio, Amaia; Lowe, Scott W; Aifantis, Iannis; Starczynowski, Daniel T 2022. TRAF6 functions as a tumor suppressor in myeloid malignancies by directly targeting MYC oncogenic activity. Cell stem cell, ,

Crowther, Rebecca R; Schmidt, Stephanie M; Lange, Shannon M; McKell, Melanie C; Robillard, Michelle C; Zhao, Junfang; Haffey, Wendy D; Wyder, Michael A; Greis, Kenneth D; Setchell, Kenneth D R; Qualls, Joseph E 2022. Cutting Edge: l-Arginine Transfer from Antigen-Presenting Cells Sustains CD4+ T Cell Viability and Proliferation. Journal of immunology (Baltimore, Md. : 1950), 208 4, 793-798

Kirley, Terence L; Norman, Andrew B; Greis, Kenneth D 2022. Oxidation of specific tryptophan residues inhibits high affinity binding of cocaine and its metabolites to a humanized anti-cocaine mAb. The Journal of biological chemistry, , 101689

Barreyro, Laura; Sampson, Avery M; Ishikawa, Chiharu; Hueneman, Kathleen M; Choi, Kwangmin; Pujato, Mario A; Chutipongtanate, Somchai; Wyder, Michael; Haffey, Wendy D; O'Brien, Eric; Wunderlich, Mark; Ramesh, Vighnesh; Kolb, Ellen M; Meydan, Cem; Neelamraju, Yaseswini; Bolanos, Lyndsey C; Christie, Susanne; Smith, Molly A; Niederkorn, Madeline; Muto, Tomoya; Kesari, Santosh; Garrett-Bakelman, Francine E; Bartholdy, Boris; Will, Britta; Weirauch, Matthew T; Mulloy, James C; Gul, Zartash; Medlin, Stephen; Kovall, Rhett A; Melnick, Ari M; Perentesis, John P; Greis, Kenneth D; Nurmemmedov, Elmar; Seibel, William L; Starczynowski, Daniel T 2022. Blocking UBE2N abrogates oncogenic immune signaling in acute myeloid leukemia. Science translational medicine, 14 635, eabb7695

Kirley, Terence L; Greis, Kenneth D; Norman, Andrew B 2022. Tyrosine nitration of a humanized anti-cocaine mAb differentially affects ligand binding of cocaine and its metabolites. Biochemistry and biophysics reports, 30 , 101278

Curry, Erin; Philpott, Megan E; Wojtusik, Jessye; Haffey, Wendy D; Wyder, Michael A; Greis, Kenneth D; Roth, Terri L 2022. Label-Free Quantification (LFQ) of Fecal Proteins for Potential Pregnancy Detection in Polar Bears. Life (Basel, Switzerland), 12 6,

Manupati, Kanakaraju; Paul, Ritama; Hao, Mingang; Haas, Michael; Bian, Zhaoqun Christine; Holm, Tammy M; Guan, Jun-Lin; Yeo, Syn Kok 2022. Biglycan Promotes Cancer Stem Cell Properties, NFĸB Signaling and Metastatic Potential in Breast Cancer Cells. Cancers, 14 2,

Yang, Yang; Gomez, Maria; Marsh, Timothy; Poillet-Perez, Laura; Sawant, Akshada; Chen, Lei; Park, Noel R; Jackson, S RaElle; Hu, Zhixian; Alon, Noa; Liu, Chen; Debnath, Jayanta; Guan, Jun-Lin; Davidson, Shawn; Verzi, Michael; White, Eileen 2022. Autophagy in PDGFR?+ mesenchymal cells is essential for intestinal stem cell survival. Proceedings of the National Academy of Sciences of the United States of America, 119 21, e2202016119

Yang, Yi; Zhu, Yifu; Zhou, Shuai; Tang, Peipei; Xu, Ran; Zhang, Yuwei; Wei, Dongping; Wen, Jian; Thorne, Rick F; Zhang, Xu Dong; Guan, Jun-Lin; Liu, Lianxin; Wu, Mian; Chen, Song 2022. TRIM27 cooperates with STK38L to inhibit ULK1-mediated autophagy and promote tumorigenesis. The EMBO journal, , e109777

Qiu, Kangqiang; Zou, Weiwei; Fang, Hongbao; Hao, Mingang; Mehta, Kritika; Tian, Zhiqi; Guan, Jun-Lin; Zhang, Kai; Huang, Taosheng; Diao, Jiajie 2022. Light-activated mitochondrial fission through optogenetic control of mitochondria-lysosome contacts. Nature communications, 13 1, 4303

Holm, Tammy M; Yeo, Syn; Turner, Kevin M; Guan, Jun-Lin 2022. Targeting Autophagy in Thyroid Cancer: EMT, Apoptosis, and Cancer Stem Cells. Frontiers in cell and developmental biology, 10 , 821855

Yi, Fei; Cai, Chunmiao; Ruan, Banzhan; Hao, Mingang; Yeo, Syn Kok; Haas, Michael; Yang, Fuchun; Zhang, Xiaoting; Guan, Jun-Lin 2022. Regulation of RB1CC1/FIP200 stability and autophagy function by CREBBP-mediated acetylation in an intrinsically disordered region. Autophagy, , 1-16

Shimanaka, Yuta; Matsumoto, Keiko; Tanaka, Yuki; Ishino, Yuki; Ni, Shenwei; Guan, Jun-Lin; Arai, Hiroyuki; Kono, Nozomu 2022. Supercritical fluid chromatography-mass spectrometry enables simultaneous measurement of all phosphoinositide regioisomers. Communications chemistry, 5 1, 61

2021

Bourn, Jennifer R; Ruiz-Torres, Sasha J; Hunt, Brian G; Benight, Nancy M; Waltz, Susan E 2021. Tumor cell intrinsic RON signaling suppresses innate immune responses in breast cancer through inhibition of IRAK4 signaling. Cancer letters, 503 , 75-90

Wicker, Christina A; Hunt, Brian G; Krishnan, Sunil; Aziz, Kathryn; Parajuli, Shobha; Palackdharry, Sarah; Elaban, William R; Wise-Draper, Trisha M; Mills, Gordon B; Waltz, Susan E; Takiar, Vinita 2021. Glutaminase inhibition with telaglenastat (CB-839) improves treatment response in combination with ionizing radiation in head and neck squamous cell carcinoma models. Cancer letters, 502 , 180-188

Vilfranc, Chrystelle L; Che, Li-Xiao; Patra, Krushna C; Niu, Liang; Olowokure, Olugbenga; Wang, Jiang; Shah, Shimul A; Du, Chun-Ying 2021. BIR repeat-containing ubiquitin conjugating enzyme (BRUCE) regulation of ?-catenin signaling in the progression of drug-induced hepatic fibrosis and carcinogenesis. World journal of hepatology, 13 3, 343-361

Czyzyk-Krzeska, Maria F; Landero Figueroa, Julio A; Gulati, Shuchi; Cunningham, John T; Meller, Jarek; ShamsaeI, Behrouz; Vemuri, Bhargav; Plas, David R 2021. Molecular and Metabolic Subtypes in Sporadic and Inherited Clear Cell Renal Cell Carcinoma. Genes, 12 3,

Czyzyk-Krzeska, Maria F; Meller, Jarek; Landero Figueroa, Julio A; Plas, David R; Cunningham, John T 2021. Metabolic subtypes of clear cell renal cell carcinoma defined by tobacco smoking. Molecular & cellular oncology, 8 2, 1859917

Reigle, James; Secic, Dina; Biesiada, Jacek; Wetzel, Collin; Shamsaei, Behrouz; Chu, Johnson; Zang, Yuanwei; Zhang, Xiang; Talbot, Nicholas J; Bischoff, Megan E; Zhang, Yongzhen; Thakar, Charuhas V; Gaitonde, Krishnanath; Sidana, Abhinav; Bui, Hai; Cunningham, John T; Zhang, Qing; Schmidt, Laura S; Linehan, W Marston; Medvedovic, Mario; Plas, David R; Figueroa, Julio A Landero; Meller, Jarek; Czyzyk-Krzeska, Maria F 2021. Tobacco smoking induces metabolic reprogramming of renal cell carcinoma. The Journal of clinical investigation, 131 1,

Wang, Chenran; Haas, Michael A; Yeo, Syn Kok; Paul, Ritama; Yang, Fuchun; Vallabhapurapu, Subrahmanya; Qi, Xiaoyang; Plas, David R; Guan, Jun-Lin 2021. Autophagy mediated lipid catabolism facilitates glioma progression to overcome bioenergetic crisis. British journal of cancer, ,

Qing, Ying; Dong, Lei; Gao, Lei; Li, Chenying; Li, Yangchan; Han, Li; Prince, Emily; Tan, Brandon; Deng, Xiaolan; Wetzel, Collin; Shen, Chao; Gao, Min; Chen, Zhenhua; Li, Wei; Zhang, Bin; Braas, Daniel; Ten Hoeve, Johanna; Sanchez, Gerardo Javier; Chen, Huiying; Chan, Lai N; Chen, Chun-Wei; Ann, David; Jiang, Lei; Müschen, Markus; Marcucci, Guido; Plas, David R; Li, Zejuan; Su, Rui; Chen, Jianjun 2021. R-2-hydroxyglutarate attenuates aerobic glycolysis in leukemia by targeting the FTO/m6A/PFKP/LDHB axis. Molecular cell, 81 5, 922-939.e9

Koehler, Abigail; Karve, Aniruddha; Desai, Pankaj; Arbiser, Jack; Plas, David R; Qi, Xiaoyang; Read, Renee D; Sasaki, Atsuo T; Gawali, Vaibhavkumar S; Toukam, Donatien K; Bhattacharya, Debanjan; Kallay, Laura; Pomeranz Krummel, Daniel A; Sengupta, Soma 2021. Reuse of Molecules for Glioblastoma Therapy. Pharmaceuticals (Basel, Switzerland), 14 2,

Bischoff, Megan E; Zang, Yuanwei; Chu, Johnson; Price, Adam D; Ehmer, Birgit; Talbot, Nicholas J; Newbold, Michael J; Paul, Anurag; Guan, Jun-Lin; Plas, David R; Meller, Jarek; Czyzyk-Krzeska, Maria F 2021. Selective MAP1LC3C (LC3C) autophagy requires noncanonical regulators and the C-terminal peptide. The Journal of cell biology, 220 7,

Zhao, Guizhen; Chang, Ziyi; Zhao, Yang; Guo, Yanhong; Lu, Haocheng; Liang, Wenying; Rom, Oren; Wang, Huilun; Sun, Jinjian; Zhu, Tianqing; Fan, Yanbo; Chang, Lin; Yang, Bo; Garcia-Barrio, Minerva T; Chen, Y Eugene; Zhang, Jifeng 2021. KLF11 protects against abdominal aortic aneurysm through inhibition of endothelial cell dysfunction. JCI insight, 6 5,

Lu, Haocheng; Sun, Jinjian; Hamblin, Milton H; Chen, Y Eugene; Fan, Yanbo 2021. Transcription factor EB regulates cardiovascular homeostasis. EBioMedicine, 63 , 103207

Liu, Yuhao; Zhao, Ying; Shukha, Yousef; Lu, Haocheng; Wang, Lu; Liu, Zhipeng; Liu, Cai; Zhao, Yang; Wang, Huilun; Zhao, Guizhen; Liang, Wenying; Fan, Yanbo; Chang, Lin; Yurdagul, Arif; Pattillo, Christopher B; Orr, A Wayne; Aviram, Michael; Wen, Bo; Garcia-Barrio, Minerva T; Zhang, Jifeng; Liu, Wanqing; Sun, Duxin; Hayek, Tony; Chen, Y Eugene; Rom, Oren 2021. Dysregulated oxalate metabolism is a driver and therapeutic target in atherosclerosis. Cell reports, 36 4, 109420

Du, Wa; Ren, Lu; Hamblin, Milton H; Fan, Yanbo 2021. Endothelial Cell Glucose Metabolism and Angiogenesis. Biomedicines, 9 2,

Lu, Haocheng; Du, Wa; Ren, Lu; Hamblin, Milton H; Becker, Richard C; Chen, Y Eugene; Fan, Yanbo 2021. Vascular Smooth Muscle Cells in Aortic Aneurysm: From Genetics to Mechanisms. Journal of the American Heart Association, , e023601

Fan, Yanbo; Wolford, Brooke N; Lu, Haocheng; Liang, Wenying; Sun, Jinjian; Zhou, Wei; Rom, Oren; Mahajan, Anubha; Surakka, Ida; Graham, Sarah E; Liu, Zhipeng; Kim, Hyunbae; Ramdas, Shweta; Fritsche, Lars G; Nielsen, Jonas B; Gabrielsen, Maiken Elvestad; Hveem, Kristian; Yang, Dongshan; Song, Jun; Garcia-Barrio, Minerva T; Zhang, Jifeng; Liu, Wanqing; Zhang, Kezhong; Willer, Cristen J; Chen, Y Eugene 2021. Type 2 diabetes sex-specific effects associated with E167K coding variant in TM6SF2. iScience, 24 11, 103196

Liang, Wenying; Lu, Haocheng; Sun, Jinjian; Zhao, Guizhen; Wang, Huilun; Guo, Yanhong; Eitzman, Daniel; Chen, Y Eugene; Fan, Yanbo; Zhang, Jifeng 2021. KLF11 Protects against Venous Thrombosis via Suppressing Tissue Factor Expression. Thrombosis and haemostasis, ,

Tang, Xin; Angst, Gabrielle; Haas, Michael; Yang, Fuchun; Wang, Chenran 2021. The Characterization of a Subependymal Giant Astrocytoma-Like Cell Line from Murine Astrocyte with mTORC1 Hyperactivation. International journal of molecular sciences, 22 8,

Wang, Chenran; Haas, Michael; Yeo, Syn Kok; Sebti, Salwa; Fernández, Álvaro F; Zou, Zhongju; Levine, Beth; Guan, Jun-Lin 2021. Enhanced autophagy in Becn1F121A/F121A knockin mice counteracts aging-related neural stem cell exhaustion and dysfunction. Autophagy, , 1-14

Liu, Hang; Wang, Chenran; Yi, Fei; Yeo, Syn; Haas, Michael; Tang, Xin; Guan, Jun-Lin 2021. Non-canonical function of FIP200 is required for neural stem cell maintenance and differentiation by limiting TBK1 activation and p62 aggregate formation. Scientific reports, 11 1, 23907

Zheng, Xiaoqiang; Yan, Jin; You, Weiming; Li, Fanni; Diao, Jiajie; He, Wangxiao; Yao, Yu 2021. De Novo Nano-Erythrocyte Structurally Braced by Biomimetic Au(I)-peptide Skeleton for MDM2/MDMX Predation toward Augmented Pulmonary Adenocarcinoma Immunotherapy. Small (Weinheim an der Bergstrasse, Germany), , e2100394

Lerner, Eitan; Barth, Anders; Hendrix, Jelle; Ambrose, Benjamin; Birkedal, Victoria; Blanchard, Scott C; Börner, Richard; Sung Chung, Hoi; Cordes, Thorben; Craggs, Timothy D; Deniz, Ashok A; Diao, Jiajie; Fei, Jingyi; Gonzalez, Ruben L; Gopich, Irina V; Ha, Taekjip; Hanke, Christian A; Haran, Gilad; Hatzakis, Nikos S; Hohng, Sungchul; Hong, Seok-Cheol; Hugel, Thorsten; Ingargiola, Antonino; Joo, Chirlmin; Kapanidis, Achillefs N; Kim, Harold D; Laurence, Ted; Lee, Nam Ki; Lee, Tae-Hee; Lemke, Edward A; Margeat, Emmanuel; Michaelis, Jens; Michalet, Xavier; Myong, Sua; Nettels, Daniel; Peulen, Thomas-Otavio; Ploetz, Evelyn; Razvag, Yair; Robb, Nicole C; Schuler, Benjamin; Soleimaninejad, Hamid; Tang, Chun; Vafabakhsh, Reza; Lamb, Don C; Seidel, Claus Am; Weiss, Shimon 2021. FRET-based dynamic structural biology: Challenges, perspectives and an appeal for open-science practices. eLife, 10 ,

Tao, Youqi; Xie, Jingfei; Zhong, Qinglu; Wang, Yongyao; Zhang, Shengnan; Luo, Feng; Wen, Fengcai; Xie, Jingjing; Zhao, Jiawei; Sun, Xiaoou; Long, Houfang; Ma, Junfeng; Zhang, Qian; Long, Jiangang; Fang, Xianyang; Lu, Ying; Li, Dan; Li, Ming; Zhu, Jidong; Sun, Bo; Li, Guohui; Diao, Jiajie; Liu, Cong 2021. A novel partially-open state of SHP2 points to a "multiple gear" regulation mechanism. The Journal of biological chemistry, , 100538

Fang, Hongbao; Geng, Shanshan; Hao, Mingang; Chen, Qixin; Liu, Minglun; Liu, Chunyan; Tian, Zhiqi; Wang, Chengjun; Takebe, Takanori; Guan, Jun-Lin; Chen, Yuncong; Guo, Zijian; He, Weijiang; Diao, Jiajie 2021. Simultaneous Zn2+ tracking in multiple organelles using super-resolution morphology-correlated organelle identification in living cells. Nature communications, 12 1, 109

Zou, Weiwei; Chen, Qixin; Slone, Jesse; Yang, Li; Lou, Xiaoting; Diao, Jiajie; Huang, Taosheng 2021. Nanoscopic quantification of sub-mitochondrial morphology, mitophagy and mitochondrial dynamics in living cells derived from patients with mitochondrial diseases. Journal of nanobiotechnology, 19 1, 136

Chen, Qixin; Hao, Mingang; Wang, Lei; Li, Linsen; Chen, Yang; Shao, Xintian; Tian, Zhiqi; Pfuetzner, Richard A; Zhong, Qing; Brunger, Axel T; Guan, Jun-Lin; Diao, Jiajie 2021. Prefused lysosomes cluster on autophagosomes regulated by VAMP8. Cell death & disease, 12 10, 939

Yan, Jin; Wang, Yang; Li, Xiao; Guo, Dongnan; Zhou, Zhengjun; Bai, Ge; Li, Jianhui; Huang, Na; Diao, Jiajie; Li, Yong; He, Wangxiao; Liu, Wenjia; Tao, Kaishan 2021. A Bionic Nano-Band-Aid Constructed by the Three-Stage Self-Assembly of Peptides for Rapid Liver Hemostasis. Nano letters, 21 17, 7166-7174

Wang, Kang-Nan; Shao, Xintian; Tian, Zhiqi; Liu, Liu-Yi; Zhang, Chengying; Tan, Cai-Ping; Zhang, Jie; Ling, Peixue; Liu, Fei; Chen, Qixin; Diao, Jiajie; Mao, Zong-Wan 2021. A Continuous Add-On Probe Reveals the Nonlinear Enlargement of Mitochondria in Light-Activated Oncosis. Advanced science (Weinheim, Baden-Wurttemberg, Germany), 8 17, e2004566

Du, Yang; Lai, Ying; Liu, Ji-Yan; Diao, Jiajie 2021. Epigenetic Quantification of DNA 5-Hydroxymethylcytosine Using DNA Hybridization-Based Single-Molecule Immunofluorescent Imaging. Small methods, 5 5, e2100061

Aryal, Chinta Mani; Tyoe, Owen; Diao, Jiajie 2021. Lipid Species Dependent Vesicles Clustering Caused by alpha-Synuclein as Revealed by Single-Vesicle Imaging with Total Internal Reflection Fluorescence Microscopy. Biophysics reports, 7 6, 437-448

Hao, Mingang; Yeo, Syn Kok; Turner, Kevin; Harold, Alexis; Yang, Yongguang; Zhang, Xiaoting; Guan, Jun-Lin 2021. Autophagy Blockade Limits HER2+ Breast Cancer Tumorigenesis by Perturbing HER2 Trafficking and Promoting Release Via Small Extracellular Vesicles. Developmental cell, 56 3, 341-355.e5

Yang, Yongguang; Leonard, Marissa; Luo, Zhenhua; Yeo, Syn; Bick, Gregory; Hao, Mingang; Cai, Chunmiao; Charif, Mahmoud; Wang, Jiang; Guan, Jun-Lin; Lower, Elyse E; Zhang, Xiaoting 2021. Functional cooperation between co-amplified genes promotes aggressive phenotypes of HER2-positive breast cancer. Cell reports, 34 10, 108822

Cai, Chunmiao; Bi, Dexi; Bick, Gregory; Wei, Qing; Liu, Hu; Lu, Ling; Zhang, Xiaoting; Qin, Huanlong 2021. Hepatocyte nuclear factor HNF1A is a potential regulator in shaping the super-enhancer landscape in colorectal cancer liver metastasis. FEBS letters, ,

Terasawa, Kazue; Kato, Yuji; Ikami, Yuta; Sakamoto, Kensaku; Ohtake, Kazumasa; Kusano, Seisuke; Tomabechi, Yuri; Kukimoto-Niino, Mutsuko; Shirouzu, Mikako; Guan, Jun-Lin; Kobayashi, Toshihide; Iwata, Takanori; Watabe, Tetsuro; Yokoyama, Shigeyuki; Hara-Yokoyama, Miki 2021. Direct homophilic interaction of LAMP2A with the two-domain architecture revealed by site-directed photo-crosslinks and steric hindrances in mammalian cells. Autophagy, , 1-19

Hao, Mingang; Yeo, Syn Kok; Guan, Jun-Lin 2021. Autophagy inhibition perturbs ERBB2 trafficking and abolishes tumorigenesis in ERBB2-driven breast cancer. Autophagy, 17 4, 1059-1060

Yi, Fei; Zhang, Ying; Wang, Zhijun; Wang, Zhuo; Li, Ziwei; Zhou, Tingting; Xu, Hongde; Liu, Jingwei; Jiang, Bo; Li, Xiaoman; Wang, Liang; Bai, Ning; Guo, Qiqiang; Guan, Yi; Feng, Yanling; Mao, Zhiyong; Fan, Guangjian; Zhang, Shengping; Wang, Chuangui; Cao, Longyue; O'Rourke, Brian P; Wang, Yang; Wu, Yanmei; Wu, Boquan; You, Shilong; Zhang, Naijin; Guan, Junlin; Song, Xiaoyu; Sun, Yingxian; Wei, Shi; Cao, Liu 2021. The deacetylation-phosphorylation regulation of SIRT2-SMC1A axis as a mechanism of antimitotic catastrophe in early tumorigenesis. Science advances, 7 9,

Turner, Kevin M; Yeo, Syn Kok; Holm, Tammy M; Shaughnessy, Elizabeth; Guan, Jun-Lin 2021. Heterogeneity Within Molecular Subtypes of Breast Cancer. American journal of physiology. Cell physiology, ,

Wang, Lingyan; Song, Kun; Hao, Wenzhuo; Wu, Yakun; Patil, Girish; Hua, Fang; Sun, Yiwen; Huang, Chaoqun; Ritchey, Jerry; Jones, Clinton; Liu, Lin; Guan, Jun-Lin; Li, Shitao 2021. FIP200 restricts RNA virus infection by facilitating RIG-I activation. Communications biology, 4 1, 921

Holm, Tammy M; Bian, Z Christine; Manupati, Kanakaraju; Guan, Jun-Lin 2021. Inhibition of autophagy mitigates cell migration and invasion in thyroid cancer. Surgery, ,

Poillet-Perez, Laura; Sharp, Daniel W; Yang, Yang; Laddha, Saurabh V; Ibrahim, Maria; Bommareddy, Praveen K; Hu, Zhixian Sherrie; Vieth, Joshua; Haas, Michael; Bosenberg, Marcus W; Rabinowitz, Joshua D; Cao, Jian; Guan, Jun-Lin; Ganesan, Shridar; Chan, Chang S; Mehnert, Janice M; Lattime, Edmund C; White, Eileen 2021. Publisher Correction: Autophagy promotes growth of tumors with high mutational burden by inhibiting a T-cell immune response. Nature cancer, 2 9, 994

2020

Hunt, Brian G; Wicker, Christina A; Bourn, Jennifer R; Lower, Elyse E; Takiar, Vinita; Waltz, Susan E 2020. MST1R (RON) expression is a novel prognostic biomarker for metastatic progression in breast cancer patients. Breast cancer research and treatment, ,

Sullivan, Camille; Brown, Nicholas E; Vasiliauskas, Juozas; Pathrose, Peterson; Starnes, Sandra L; Waltz, Susan E 2020. Prostate Epithelial RON Signaling Promotes M2 Macrophage Activation to Drive Prostate Tumor Growth and Progression. Molecular cancer research : MCR, ,

Pease, Nicholas A; Shephard, Miranda S; Sertorio, Mathieu; Waltz, Susan E; Vinnedge, Lisa M Privette 2020. DEK Expression in Breast Cancer Cells Leads to the Alternative Activation of Tumor Associated Macrophages. Cancers, 12 7,

Qiao, Shuxi; Koh, Siang-Boon; Vivekanandan, Varunika; Salunke, Devika; Patra, Krushna Chandra; Zaganjor, Elma; Ross, Kenneth; Mizukami, Yusuke; Jeanfavre, Sarah; Chen, Athena; Mino-Kenudson, Mari; Ramaswamy, Sridhar; Clish, Clary; Haigis, Marcia; Bardeesy, Nabeel; Ellisen, Leif W 2020. REDD1 loss reprograms lipid metabolism to drive progression of RAS mutant tumors. Genes & development, ,

Ren, Yan; Sivaganesan, Siva; Clark, Nicholas A; Zhang, Lixia; Biesiada, Jacek; Niu, Wen; Plas, David R; Medvedovic, Mario 2020. Predicting mechanism of action of cellular perturbations with pathway activity signatures. Bioinformatics (Oxford, England), ,

Sarma, Pranjal; Plas, David R 2020. Choreography of methylation: KDM4C histone demethylation enables ALKBH5 m6A RNA demethylation to sustain AML stem cells. Blood science (Baltimore, Md.), 2 4, 144-145

Che, Lixiao; Alavattam, Kris G; Stambrook, Peter J; Namekawa, Satoshi H; Du, Chunying 2020. BRUCE preserves genomic stability in the male germline of mice. Cell death and differentiation, ,

Zhao, Yang; Chang, Ziyi; Zhao, Guizhen; Lu, Haocheng; Xiong, Wenhao; Liang, Wenying; Wang, Huilun; Villacorta, Luis; Garcia-Barrio, Minerva T; Zhu, Tianqing; Guo, Yanhong; Fan, Yanbo; Chang, Lin; Schopfer, Francisco J; Freeman, Bruce A; Zhang, Jifeng; Chen, Y Eugene 2020. Suppression of Vascular Macrophage Activation by Nitro-Oleic Acid and its Implication for Abdominal Aortic Aneurysm Therapy. Cardiovascular drugs and therapy, ,

Lu, Haocheng; Sun, Jinjian; Liang, Wenying; Chang, Ziyi; Rom, Oren; Zhao, Yang; Zhao, Guizhen; Xiong, Wenhao; Wang, Huilun; Zhu, Tianqing; Guo, Yanhong; Chang, Lin; Garcia-Barrio, Minerva T; Zhang, Jifeng; Chen, Y Eugene; Fan, Yanbo 2020. Cyclodextrin Prevents Abdominal Aortic Aneurysm via Activation of Vascular Smooth Muscle Cell TFEB. Circulation, ,

Sun, Yifang; Venugopal, Jessica; Guo, Chiao; Fan, Yanbo; Li, Jianping; Gong, Yanjun; Chen, Y Eugene; Zhang, Haoming; Eitzman, Daniel T 2020. Clopidogrel Resistance in a Murine Model of Diet-Induced Obesity Is Mediated by the Interleukin-1 Receptor and Overcome With DT-678. Arteriosclerosis, thrombosis, and vascular biology, , ATVBAHA120314146

Chang, Ziyi; Zhao, Guizhen; Zhao, Yang; Lu, Haocheng; Xiong, Wenhao; Liang, Wenying; Sun, Jinjian; Wang, Huilun; Zhu, Tianqing; Rom, Oren; Guo, Yanhong; Fan, Yanbo; Chang, Lin; Yang, Bo; Garcia-Barrio, Minerva T; Lin, Jiandie D; Chen, Y Eugene; Zhang, Jifeng 2020. BAF60a Deficiency in Vascular Smooth Muscle Cells Prevents Abdominal Aortic Aneurysm by Reducing Inflammation and Extracellular Matrix Degradation. Arteriosclerosis, thrombosis, and vascular biology, 40 10, 2494-2507

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