Cancer Biology Publications

2025

MacMillan, Austin C; Karki, Bibek; Yang, Juechen; Gertz, Karmela R; Zumwalde, Samantha; Czyzyk-Krzeska, Maria F; Meller, Jarek; Cunningham, John T 2025. PRPS activity tunes redox homeostasis in Myc-driven lymphoma. bioRxiv : the preprint server for biology, ,

2024

Bischoff, Megan E; Shamsaei, Behrouz; Yang, Juechen; Secic, Dina; Vemuri, Bhargav; Reisz, Julie A; D'Alessandro, Angelo; Bartolacci, Caterina; Adamczak, Rafal; Schmidt, Lucas; Wang, Jiang; Martines, Amelia; Biesiada, Jacek; Vest, Katherine E; Scaglioni, Pier P; Plas, David R; Patra, Krushna C; Gulati, Shuchi; Figueroa, Julio A Landero; Meller, Jarek; Cunningham, J Tom; Czyzyk-Krzeska, Maria F 2024. Copper drives remodeling of metabolic state and progression of clear cell renal cell carcinoma. bioRxiv : the preprint server for biology, ,

Xue, Meilin; Dong, Lei; Zhang, Honghai; Li, Yangchan; Qiu, Kangqiang; Zhao, Zhicong; Gao, Min; Han, Li; Chan, Anthony K N; Li, Wei; Leung, Keith; Wang, Kitty; Pokharel, Sheela Pangeni; Qing, Ying; Liu, Wei; Wang, Xueer; Ren, Lili; Bi, Hongjie; Yang, Lu; Shen, Chao; Chen, Zhenhua; Melstrom, Laleh; Li, Hongzhi; Timchenko, Nikolai; Deng, Xiaolan; Huang, Wendong; Rosen, Steven T; Tian, Jingyan; Xu, Lin; Diao, Jiajie; Chen, Chun-Wei; Chen, Jianjun; Shen, Baiyong; Chen, Hao; Su, Rui 2024. METTL16 promotes liver cancer stem cell self-renewal via controlling ribosome biogenesis and mRNA translation. Journal of hematology & oncology, 17 1, 7

Diao, Jiajie; Yip, Calvin K; Zhong, Qing 2024. Molecular structures and function of the autophagosome-lysosome fusion machinery. Autophagy reports, 3 1,

Bischoff, Megan E; Shamsaei, Behrouz; Yang, Juechen; Secic, Dina; Vemuri, Bhargav; Reisz, Julie A; D'Alessandro, Angelo; Bartolacci, Caterina; Adamczak, Rafal; Schmidt, Lucas; Wang, Jiang; Martines, Amelia; Venkat, Jahnavi; Toffessi Tcheuyap, Vanina; Biesiada, Jacek; Behrmann, Catherine A; Vest, Katherine E; Brugarolas, James; Scaglioni, Pier Paolo; Plas, David R; Patra, Krushna C; Gulati, Shuchi; Landero Figueroa, Julio A; Meller, Jarek; Cunningham, John T; Czyzyk-Krzeska, Maria F 2024. Copper drives remodeling of metabolic state and progression of clear cell renal cell carcinoma. Cancer discovery, ,

Thorman, Alexander W; Reigle, James; Chutipongtanate, Somchai; Yang, Juechen; Shamsaei, Behrouz; Pilarczyk, Marcin; Fazel-Najafabadi, Mehdi; Adamczak, Rafal; Kouril, Michal; Bhatnagar, Surbhi; Hummel, Sarah; Niu, Wen; Morrow, Ardythe L; Czyzyk-Krzeska, Maria F; McCullumsmith, Robert; Seibel, William; Nassar, Nicolas; Zheng, Yi; Hildeman, David A; Medvedovic, Mario; Herr, Andrew B; Meller, Jarek 2024. Accelerating drug discovery and repurposing by combining transcriptional signature connectivity with docking. Science advances, 10 35, eadj3010

Behrmann, Catherine A; Ennis, Kelli N; Sarma, Pranjal; Wetzel, Collin; Clark, Nicholas A; Von Handorf, Kate M; Vallabhapurapu, Subrahmanya; Andreani, Cristina; Reigle, James; Scaglioni, Pier Paolo; Meller, Jarek; Czyzyk-Krzeska, Maria F; Kendler, Ady; Qi, Xiaoyang; Sarkaria, Jann N; Medvedovic, Mario; Sengupta, Soma; Dasgupta, Biplab; Plas, David R 2024. Coordinated Targeting of S6K1/2 and AXL Disrupts Pyrimidine Biosynthesis in PTEN-Deficient Glioblastoma. Cancer research communications, 4 8, 2215-2227

Hao, Mingang; Lu, Peixin; Sotropa, Sarah; Manupati, Kanakaraju; Yeo, Syn Kok; Guan, Jun-Lin 2024. In vivo CRISPR knockout screen identifies p47 as a suppressor of HER2+ breast cancer metastasis by regulating NEMO trafficking and autophagy flux. Cell reports, 43 2, 113780

Sakuma, Chisato; Shizukuishi, Sayaka; Ogawa, Michinaga; Honjo, Yuko; Takeyama, Haruko; Guan, Jun-Lin; Weiser, Jeffery; Sasai, Miwa; Yamamoto, Masahiro; Ohnishi, Makoto; Akeda, Yukihiro 2024. Individual Atg8 paralogs and a bacterial metabolite sequentially promote hierarchical CASM-xenophagy induction and transition. Cell reports, 43 5, 114131

Liu, Han; Su, Peihong; Li, Yuanyuan; Hoover, Alex; Hu, Sophie; King, Sarah A; Zhao, Jing; Guan, Jun-Lin; Chen, Shao-Yu; Zhao, Yingming; Tan, Minjia; Wu, Xiaoyang 2024. VAMP2 controls murine epidermal differentiation and carcinogenesis by regulation of nucleophagy. Developmental cell, ,

Manupati, Kanakaraju; Hao, Mingang; Haas, Michael; Yeo, Syn Kok; Guan, Jun-Lin 2024. Role of NuMA1 in breast cancer stem cells with implications for combination therapy of PIM1 and autophagy inhibition in triple negative breast cancer. Research square, ,

Davis, James C; Waltz, Susan E 2024. The MET Family of Receptor Tyrosine Kinases Promotes a Shift to Pro-Tumor Metabolism. Genes, 15 7,

Hazra, Aditi; Goldstein, Karen M; Waltz, Susan E; Chiba, Akiko; Colonna, Sarah V; Kelley, Michael J; Moss, Haley A; Zullig, Leah L 2024. Summary and Roadmap of Breast Cancer Research in the Veterans Affairs. Military medicine, ,

Korns, Julianna; Wicker, Christina A; Lehn, Maria; Shyamsunder, Shreya; Thompson, Samuel; Lester, Carissa; Wise-Draper, Trisha M; Waltz, Susan E; Takiar, Vinita 2024. Telaglenastat as an alternative to cisplatin as a radiosensitizer in the treatment of head and neck squamous cell carcinoma. Cancer letters, , 217320

Vicente-Muñoz, Sara; Davis, James C; Lane, Adam; Lane, Andrew N; Waltz, Susan E; Wells, Susanne I 2024. Lipid profiling of RON and DEK-dependent signaling in breast cancer guides discovery of gene networks predictive of poor outcomes. Frontiers in oncology, 14 , 1382986

2023

Andreani, Cristina; Bartolacci, Caterina; Persico, Giuseppe; Casciaro, Francesca; Amatori, Stefano; Fanelli, Mirco; Giorgio, Marco; Galié, Mirco; Tomassoni, Daniele; Wang, Junbiao; Zhang, Xiaoting; Bick, Gregory; Coppari, Roberto; Marchini, Cristina; Amici, Augusto 2023. SIRT6 promotes metastasis and relapse in HER2-positive breast cancer. Scientific reports, 13 1, 22000

Yi, Fei; Cai, Chunmiao; Ruan, Banzhan; Hao, Mingang; Yeo, Syn Kok; Haas, Michael; Yang, Fuchun; Zhang, Xiaoting; Guan, Jun-Lin 2023. Regulation of RB1CC1/FIP200 stability and autophagy function by CREBBP-mediated acetylation in an intrinsically disordered region. Autophagy, 19 6, 1662-1677

Chan, Gary K L; Maisel, Samantha; Hwang, Yeonjoo C; Pascual, Bryan C; Wolber, Rebecca R B; Vu, Phuong; Patra, Krushna C; Bouhaddou, Mehdi; Kenerson, Heidi L; Lim, Huat C; Long, Donald; Yeung, Raymond S; Sethupathy, Praveen; Swaney, Danielle L; Krogan, Nevan J; Turnham, Rigney E; Riehle, Kimberly J; Scott, John D; Bardeesy, Nabeel; Gordan, John D 2023. Oncogenic PKA signaling increases c-MYC protein expression through multiple targetable mechanisms. eLife, 12 ,

Shin, Sejeong; Han, Min-Joon; Jedrychowski, Mark P; Zhang, Ziyang; Shokat, Kevan M; Plas, David R; Dephoure, Noah; Yoon, Sang-Oh 2023. mTOR inhibition reprograms cellular proteostasis by regulating eIF3D-mediated selective mRNA translation and promotes cell phenotype switching. Cell reports, 42 8, 112868

Garrett, Matthew C; Albano, Rebecca; Carnwath, Troy; Elahi, Lubayna; Behrmann, Catherine A; Pemberton, Merissa; Woo, Daniel; O'Brien, Eric; VanCauwenbergh, Brett; Perentesis, John; Shah, Sanjit; Hagan, Matthew; Kendler, Ady; Zhao, Chuntao; Paranjpe, Aditi; Roskin, Krishna; Kornblum, Harley; Plas, David R; Lu, Q Richard 2023. HDAC1 and HDAC6 are essential for driving growth in IDH1 mutant glioma. Scientific reports, 13 1, 12433

Verma, Rita; Aggarwal, Parul; Bischoff, Megan E; Reigle, James; Secic, Dina; Wetzel, Collin; VandenHeuvel, Katherine; Biesiada, Jacek; Ehmer, Birgit; Landero Figueroa, Julio A; Plas, David R; Medvedovic, Mario; Meller, Jarek; Czyzyk-Krzeska, Maria F 2023. Microtubule-associated protein MAP1LC3C regulates lysosomal exocytosis and induces zinc reprogramming in renal cancer cells. The Journal of biological chemistry, 299 5, 104663

Ren, Lu; Du, Wa; Song, Dan; Lu, Haocheng; Hamblin, Milton H; Wang, Chenran; Du, Chunying; Fan, Guo-Chang; Becker, Richard C; Fan, Yanbo 2023. Genetic ablation of diabetes-associated gene Ccdc92 reduces obesity and insulin resistance in mice. iScience, 26 1, 105769

Chen, Qixin; Liu, Liu-Yi; Tian, Zhiqi; Fang, Zhou; Wang, Kang-Nan; Shao, Xintian; Zhang, Chengying; Zou, Weiwei; Rowan, Fiona; Qiu, Kangqiang; Ji, Baohua; Guan, Jun-Lin; Li, Dechang; Mao, Zong-Wan; Diao, Jiajie 2023. Mitochondrial nucleoid condensates drive peripheral fission through high membrane curvature. Cell reports, 42 12, 113472

Xu, Xiuqiong; Qiu, Kangqiang; Tian, Zhiqi; Aryal, Chinta; Rowan, Fiona; Chen, Rui; Sun, Yujie; Diao, Jiajie 2023. Probing the dynamic crosstalk of lysosomes and mitochondria with structured illumination microscopy. Trends in analytical chemistry : TRAC, 169 ,

Qiu, Kangqiang; Tian, Zhiqi; Diao, Jiajie 2023. Monitoring lysosomal acidity. Nature chemical biology, 19 12, 1434-1435

Chen, Rui; Qiu, Kangqiang; Leong, Daniel C Y; Kundu, Bidyut Kumar; Zhang, Chengying; Srivastava, Prasenjit; White, Katie E; Li, Guodong; Han, Guanqun; Guo, Ziyuan; Elles, Christopher G; Diao, Jiajie; Sun, Yujie 2023. A general design of pyridinium-based fluorescent probes for enhancing two-photon microscopy. Biosensors & bioelectronics, 239 , 115604

Lai, Ying; Zhao, Chunyu; Tian, Zhiqi; Wang, Chuchu; Fan, Jiaqi; Hu, Xiao; Tu, Jia; Li, Tihui; Leitz, Jeremy; Pfuetzner, Richard A; Liu, Zhengtao; Zhang, Shengnan; Su, Zhaoming; Burré, Jacqueline; Li, Dan; Südhof, Thomas C; Zhu, Zheng-Jiang; Liu, Cong; Brunger, Axel T; Diao, Jiajie 2023. Neutral lysophosphatidylcholine mediates α-synuclein-induced synaptic vesicle clustering. Proceedings of the National Academy of Sciences of the United States of America, 120 44, e2310174120

Tyoe, Owen; Aryal, Chinta; Diao, Jiajie 2023. Docosahexaenoic acid promotes vesicle clustering mediated by alpha-Synuclein via electrostatic interaction. The European physical journal. E, Soft matter, 46 10, 96

Chen, Rui; Qiu, Kangqiang; Han, Guanqun; Kundu, Bidyut Kumar; Ding, Guodong; Sun, Yujie; Diao, Jiajie 2023. Quantifying cell viability through organelle ratiometric probing. Chemical science, 14 37, 10236-10248

Wang, Yuxin; Chan, Yun-Sheng; Chae, Matthew; Shi, Donglu; Lee, Chen-Yi; Diao, Jiajie 2023. Programmable Digital-Microfluidic Biochips for SARS-CoV-2 Detection. Bioengineering (Basel, Switzerland), 10 8,

Zhang, Chengying; Tian, Zhiqi; Chen, Rui; Rowan, Fiona; Qiu, Kangqiang; Sun, Yujie; Guan, Jun-Lin; Diao, Jiajie 2023. Advanced imaging techniques for tracking drug dynamics at the subcellular level. Advanced drug delivery reviews, 199 , 114978

Bu, Bing; Tian, Zhiqi; Li, Dechang; Zhang, Kai; Chen, Wei; Ji, Baohua; Diao, Jiajie 2023. Double-Transmembrane Domain of SNAREs Decelerates the Fusion by Increasing the Protein-Lipid Mismatch. Journal of molecular biology, 435 13, 168089

Chen, Rui; Wang, Lei; Ding, Guodong; Han, Guanqun; Qiu, Kangqiang; Sun, Yujie; Diao, Jiajie 2023. Constant Conversion Rate of Endolysosomes Revealed by a pH-Sensitive Fluorescent Probe. ACS sensors, 8 5, 2068-2078

Qiu, Kangqiang; Zou, Weiwei; Fang, Zhou; Wang, Yuxin; Bell, Sam; Zhang, Xiang; Tian, Zhiqi; Xu, Xiuqiong; Ji, Baohua; Li, Dechang; Huang, Taosheng; Diao, Jiajie 2023. 2D MoS2 and BN Nanosheets Damage Mitochondria through Membrane Penetration. ACS nano, 17 5, 4716-4728

Li, Dechang; Diao, Jiajie 2023. Protein-Membrane Interaction at the Pre-Synapse. Journal of molecular biology, 435 1, 167905

Fang, Hongbao; Hu, Lianting; Chen, Qixin; Geng, Shanshan; Qiu, Kangqiang; Wang, Chengjun; Hao, Mingang; Tian, Zhiqi; Chen, Huimin; Liu, Lei; Guan, Jun-Lin; Chen, Yuncong; Dong, Lei; Guo, Zijian; He, Weijiang; Diao, Jiajie 2023. An ER-targeted "reserve-release" fluorogen for topological quantification of reticulophagy. Biomaterials, 292 , 121929

Dean, Sarai T; Ishikawa, Chiharu; Zhu, Xiaoqin; Walulik, Sean; Nixon, Timothy; Jordan, Jessica K; Henderson, Samantha; Wyder, Michael; Salomonis, Nathan; Wunderlich, Mark; Greis, Kenneth D; Starczynowski, Daniel T; Volk, Andrew G 2023. Repression of TRIM13 by chromatin assembly factor CHAF1B is critical for AML development. Blood advances, ,

Bennett, Joshua Ruina; Ishikawa, Chiharu; Agarwal, Puneet; Yeung, Jennifer; Sampson, Avery; Uible, Emma; Vick, Eric; Bolanos, Lyndsey; Hueneman, Kathleen M; Wunderlich, Mark; Kolt, Amal; Choi, Kwangmin; Volk, Andrew G; Greis, Kenneth D; Rosenbaum, Jan S; Hoyt, Scott; Thomas, Craig J; Starczynowski, Daniel T 2023. Paralog-specific signaling by IRAK1/4 maintains MyD88-independent functions in MDS/AML. Blood, ,

Uehara, Yasuaki; Tanaka, Yusuke; Zhao, Shuyang; Nikolaidis, Nikolaos M; Pitstick, Lori B; Wu, Huixing; Yu, Jane J; Zhang, Erik; Hasegawa, Yoshihiro; Noel, John G; Gardner, Jason C; Kopras, Elizabeth J; Haffey, Wendy D; Greis, Kenneth D; Guo, Jinbang; Woods, Jason C; Wikenheiser-Brokamp, Kathryn A; Kyle, Jennifer E; Ansong, Charles; Teitelbaum, Steven L; Inoue, Yoshikazu; Altinişik, Göksel; Xu, Yan; McCormack, Francis X 2023. Insights into pulmonary phosphate homeostasis and osteoclastogenesis emerge from the study of pulmonary alveolar microlithiasis. Nature communications, 14 1, 1205

Yang, Fuchun; Kalantari, Shiva; Ruan, Banzhan; Sun, Shaogang; Bian, Zhaoqun; Guan, Jun-Lin 2023. Autophagy inhibition prevents lymphatic malformation progression to lymphangiosarcoma by decreasing osteopontin and Stat3 signaling. Nature communications, 14 1, 978

Yang, Fuchun; Guan, Jun-Lin 2023. Autophagy-dependent expression of osteopontin and its downstream Stat3 signaling contributes to lymphatic malformation progression to lymphangiosarcoma. Autophagy, , 1-2

Yeo, Syn Kok; Haas, Michael; Manupati, Kanakaraju; Hao, Mingang; Yang, Fuchun; Chen, Song; Guan, Jun-Lin 2023. AZI2 mediates TBK1 activation at unresolved selective autophagy cargo receptor complexes with implications for CD8 T-cell infiltration in breast cancer. Autophagy, , 1-16

Hunt, Brian G; Fox, Levi H; Davis, James C; Jones, Angelle; Lu, Zhixin; Waltz, Susan E 2023. An Introduction and Overview of RON Receptor Tyrosine Kinase Signaling. Genes, 14 2,

Oropeza, Elena; Seker, Sinem; Carrel, Sabrina; Mazumder, Aloran; Lozano, Daniel; Jimenez, Athena; VandenHeuvel, Sabrina N; Noltensmeyer, Dillon A; Punturi, Nindo B; Lei, Jonathan T; Lim, Bora; Waltz, Susan E; Raghavan, Shreya A; Bainbridge, Matthew N; Haricharan, Svasti 2023. Molecular portraits of cell cycle checkpoint kinases in cancer evolution, progression, and treatment responsiveness. Science advances, 9 26, eadf2860

Hunt, Brian G; Davis, James C; Fox, Levi H; Vicente-Muñoz, Sara; Lester, Carissa; Wells, Susanne I; Waltz, Susan E 2023. RON-augmented cholesterol biosynthesis in breast cancer metastatic progression and recurrence. Oncogene, 42 21, 1716-1727

2022

Bick, Gregory; Zhang, Jasmine; Lower, Elyse E; Zhang, Xiaoting 2022. Transcriptional coactivator MED1 in the interface of anti-estrogen and anti-HER2 therapeutic resistance. Cancer drug resistance (Alhambra, Calif.), 5 2, 498-510

Blaha, Catherine S; Ramakrishnan, Gopalakrishnan; Jeon, Sang-Min; Nogueira, Veronique; Rho, Hyunsoo; Kang, Soeun; Bhaskar, Prashanth; Terry, Alexander R; Aissa, Alexandre F; Frolov, Maxim V; Patra, Krushna C; Brooks Robey, R; Hay, Nissim 2022. A non-catalytic scaffolding activity of hexokinase 2 contributes to EMT and metastasis. Nature communications, 13 1, 899

Karve, Aniruddha S; Desai, Janki M; Dave, Nimita; Wise-Draper, Trisha M; Gudelsky, Gary A; Phoenix, Timothy N; DasGupta, Biplab; Sengupta, Soma; Plas, David R; Desai, Pankaj B 2022. Potentiation of temozolomide activity against glioblastoma cells by aromatase inhibitor letrozole. Cancer chemotherapy and pharmacology, 90 4, 345-356

Garrett, Matthew C; Albano, Rebecca; Carnwath, Troy; Shah, Sanjit; Woo, Daniel; Lamba, Michael; Plas, David R; Paranjpe, Aditi; Roskin, Krishna; Zhao, Chuntao; Lu, Richard 2022. Chromatin structure predicts survival in glioma patients. Scientific reports, 12 1, 8221

Qiu, Kangqiang; Seino, Ryo; Han, Guanqun; Ishiyama, Munetaka; Ueno, Yuichiro; Tian, Zhiqi; Sun, Yujie; Diao, Jiajie 2022. De novo Design of A Membrane-anchored Probe for Multi-dimensional Quantification of Endocytic Dynamics. Advanced healthcare materials, , e2102185

Shannon, Daniel; Gruber, Weston; Lohmueller, Isaac; Hawryschuk, Ethan; Medley, Wyatt; Poetker, Gavin; Diao, JaiJie 2022. The role of FIP200 in Phagophore formation during Autophagy. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 36 Suppl 1 ,

Wang, Lei; Diao, Jiajie 2022. VAMP8 phosphorylation regulates lysosome dynamics during autophagy. Autophagy reports, 1 1, 79-82

Wu, Kai; Sun, Wuxuepeng; Li, Dechang; Diao, Jiajie; Xiu, Peng 2022. Inhibition of Amyloid Nucleation by Steric Hindrance. The journal of physical chemistry. B, 126 48, 10045-10054

Gamage, Dilani G; Melikov, Kamran; Munoz-Tello, Paola; Wherley, Tanner J; Focke, Leah C; Leikina, Evgenia; Huffman, Elliana; Diao, Jiajie; Kojetin, Douglas J; Prasad, Vikram; Chernomordik, Leonid V; Millay, Douglas P 2022. Phosphatidylserine orchestrates Myomerger membrane insertions to drive myoblast fusion. Proceedings of the National Academy of Sciences of the United States of America, 119 38, e2202490119

Fang, Guiqian; Chen, Huimin; Shao, Xintian; Wang, Han; Zhan, Dongxue; Wang, Ran; Meng, Peng; Fang, Hongbao; Liu, Fei; Ling, Peixue; Wu, Zhongyu; Diao, Jiajie; Yao, Qingqiang; Chen, Qixin 2022. Single Image Capture of Bioactive Ion Crosstalk within Inter-Organelle Membrane Contacts at Nanometer Resolution. Small methods, 6 8, e2200321

Qiu, Kangqiang; Zou, Weiwei; Fang, Hongbao; Hao, Mingang; Mehta, Kritika; Tian, Zhiqi; Guan, Jun-Lin; Zhang, Kai; Huang, Taosheng; Diao, Jiajie 2022. Light-activated mitochondrial fission through optogenetic control of mitochondria-lysosome contacts. Nature communications, 13 1, 4303

Wang, Lei; Chen, Rui; Han, Guanqun; Liu, Xuan; Huang, Taosheng; Diao, Jiajie; Sun, Yujie 2022. Super-resolution analyzing spatial organization of lysosomes with an organic fluorescent probe. Exploration (Beijing, China), 2 3,

Muto, Tomoya; Guillamot, Maria; Yeung, Jennifer; Fang, Jing; Bennett, Joshua; Nadorp, Bettina; Lasry, Audrey; Redondo, Luna Zea; Choi, Kwangmin; Gong, Yixiao; Walker, Callum S; Hueneman, Kathleen; Bolanos, Lyndsey C; Barreyro, Laura; Lee, Lynn H; Greis, Kenneth D; Vasyliev, Nikita; Khodadadi-Jamayran, Alireza; Nudler, Evgeny; Lujambio, Amaia; Lowe, Scott W; Aifantis, Iannis; Starczynowski, Daniel T 2022. TRAF6 functions as a tumor suppressor in myeloid malignancies by directly targeting MYC oncogenic activity. Cell stem cell, ,

Crowther, Rebecca R; Schmidt, Stephanie M; Lange, Shannon M; McKell, Melanie C; Robillard, Michelle C; Zhao, Junfang; Haffey, Wendy D; Wyder, Michael A; Greis, Kenneth D; Setchell, Kenneth D R; Qualls, Joseph E 2022. Cutting Edge: l-Arginine Transfer from Antigen-Presenting Cells Sustains CD4+ T Cell Viability and Proliferation. Journal of immunology (Baltimore, Md. : 1950), 208 4, 793-798

Kirley, Terence L; Norman, Andrew B; Greis, Kenneth D 2022. Oxidation of specific tryptophan residues inhibits high affinity binding of cocaine and its metabolites to a humanized anti-cocaine mAb. The Journal of biological chemistry, , 101689

Barreyro, Laura; Sampson, Avery M; Ishikawa, Chiharu; Hueneman, Kathleen M; Choi, Kwangmin; Pujato, Mario A; Chutipongtanate, Somchai; Wyder, Michael; Haffey, Wendy D; O'Brien, Eric; Wunderlich, Mark; Ramesh, Vighnesh; Kolb, Ellen M; Meydan, Cem; Neelamraju, Yaseswini; Bolanos, Lyndsey C; Christie, Susanne; Smith, Molly A; Niederkorn, Madeline; Muto, Tomoya; Kesari, Santosh; Garrett-Bakelman, Francine E; Bartholdy, Boris; Will, Britta; Weirauch, Matthew T; Mulloy, James C; Gul, Zartash; Medlin, Stephen; Kovall, Rhett A; Melnick, Ari M; Perentesis, John P; Greis, Kenneth D; Nurmemmedov, Elmar; Seibel, William L; Starczynowski, Daniel T 2022. Blocking UBE2N abrogates oncogenic immune signaling in acute myeloid leukemia. Science translational medicine, 14 635, eabb7695

Kirley, Terence L; Greis, Kenneth D; Norman, Andrew B 2022. Tyrosine nitration of a humanized anti-cocaine mAb differentially affects ligand binding of cocaine and its metabolites. Biochemistry and biophysics reports, 30 , 101278

Curry, Erin; Philpott, Megan E; Wojtusik, Jessye; Haffey, Wendy D; Wyder, Michael A; Greis, Kenneth D; Roth, Terri L 2022. Label-Free Quantification (LFQ) of Fecal Proteins for Potential Pregnancy Detection in Polar Bears. Life (Basel, Switzerland), 12 6,

Manupati, Kanakaraju; Paul, Ritama; Hao, Mingang; Haas, Michael; Bian, Zhaoqun Christine; Holm, Tammy M; Guan, Jun-Lin; Yeo, Syn Kok 2022. Biglycan Promotes Cancer Stem Cell Properties, NFĸB Signaling and Metastatic Potential in Breast Cancer Cells. Cancers, 14 2,

Yang, Yang; Gomez, Maria; Marsh, Timothy; Poillet-Perez, Laura; Sawant, Akshada; Chen, Lei; Park, Noel R; Jackson, S RaElle; Hu, Zhixian; Alon, Noa; Liu, Chen; Debnath, Jayanta; Guan, Jun-Lin; Davidson, Shawn; Verzi, Michael; White, Eileen 2022. Autophagy in PDGFR?+ mesenchymal cells is essential for intestinal stem cell survival. Proceedings of the National Academy of Sciences of the United States of America, 119 21, e2202016119

Yang, Yi; Zhu, Yifu; Zhou, Shuai; Tang, Peipei; Xu, Ran; Zhang, Yuwei; Wei, Dongping; Wen, Jian; Thorne, Rick F; Zhang, Xu Dong; Guan, Jun-Lin; Liu, Lianxin; Wu, Mian; Chen, Song 2022. TRIM27 cooperates with STK38L to inhibit ULK1-mediated autophagy and promote tumorigenesis. The EMBO journal, , e109777

Holm, Tammy M; Yeo, Syn; Turner, Kevin M; Guan, Jun-Lin 2022. Targeting Autophagy in Thyroid Cancer: EMT, Apoptosis, and Cancer Stem Cells. Frontiers in cell and developmental biology, 10 , 821855

Shimanaka, Yuta; Matsumoto, Keiko; Tanaka, Yuki; Ishino, Yuki; Ni, Shenwei; Guan, Jun-Lin; Arai, Hiroyuki; Kono, Nozomu 2022. Supercritical fluid chromatography-mass spectrometry enables simultaneous measurement of all phosphoinositide regioisomers. Communications chemistry, 5 1, 61

Ruiz-Torres, Sasha J; Bourn, Jennifer R; Benight, Nancy M; Hunt, Brian G; Lester, Carissa; Waltz, Susan E 2022. Macrophage-mediated RON signaling supports breast cancer growth and progression through modulation of IL-35. Oncogene, 41(3) Jan, 321-333

Hunt, Brian G; Jones, Angelle; Lester, Carissa; Davis, James C; Benight, Nancy M; Waltz, Susan E 2022. RON (MST1R) and HGFL (MST1) Co-Overexpression Supports Breast Tumorigenesis through Autocrine and Paracrine Cellular Crosstalk. Cancers, 14 10,

Brown, Nicholas E; Jones, Angelle; Hunt, Brian G; Waltz, Susan E 2022. Prostate tumor RON receptor signaling mediates macrophage recruitment to drive androgen deprivation therapy resistance through Gas6-mediated Axl and RON signaling. The Prostate, ,

Vicente-Muñoz, Sara; Hunt, Brian G; Lange, Taylor E; Wells, Susanne I; Waltz, Susan E 2022. NMR-based metabolomic analysis identifies RON-DEK-?-catenin dependent metabolic pathways and a gene signature that stratifies breast cancer patient survival. PloS one, 17 9, e0274128

2021

Yang Y, Leonard M, Luo Q, Yeo S, Bick G, Hao M, Cai C, Charif M, Wang J, Guan J, Lower EE and Zhang X. 2021. Functional cooperation between Co-amplfied Genes Promotes Aggressive Phenotypes of HER2+ breast cancer Cell Reports , ,

Hao, Mingang; Yeo, Syn Kok; Turner, Kevin; Harold, Alexis; Yang, Yongguang; Zhang, Xiaoting; Guan, Jun-Lin 2021. Autophagy Blockade Limits HER2+ Breast Cancer Tumorigenesis by Perturbing HER2 Trafficking and Promoting Release Via Small Extracellular Vesicles. Developmental cell, 56 3, 341-355.e5

Yang, Yongguang; Leonard, Marissa; Luo, Zhenhua; Yeo, Syn; Bick, Gregory; Hao, Mingang; Cai, Chunmiao; Charif, Mahmoud; Wang, Jiang; Guan, Jun-Lin; Lower, Elyse E; Zhang, Xiaoting 2021. Functional cooperation between co-amplified genes promotes aggressive phenotypes of HER2-positive breast cancer. Cell reports, 34 10, 108822

Cai, Chunmiao; Bi, Dexi; Bick, Gregory; Wei, Qing; Liu, Hu; Lu, Ling; Zhang, Xiaoting; Qin, Huanlong 2021. Hepatocyte nuclear factor HNF1A is a potential regulator in shaping the super-enhancer landscape in colorectal cancer liver metastasis. FEBS letters, ,

Vilfranc, Chrystelle L; Che, Li-Xiao; Patra, Krushna C; Niu, Liang; Olowokure, Olugbenga; Wang, Jiang; Shah, Shimul A; Du, Chun-Ying 2021. BIR repeat-containing ubiquitin conjugating enzyme (BRUCE) regulation of ?-catenin signaling in the progression of drug-induced hepatic fibrosis and carcinogenesis. World journal of hepatology, 13 3, 343-361

Czyzyk-Krzeska, Maria F; Landero Figueroa, Julio A; Gulati, Shuchi; Cunningham, John T; Meller, Jarek; ShamsaeI, Behrouz; Vemuri, Bhargav; Plas, David R 2021. Molecular and Metabolic Subtypes in Sporadic and Inherited Clear Cell Renal Cell Carcinoma. Genes, 12 3,

Czyzyk-Krzeska, Maria F; Meller, Jarek; Landero Figueroa, Julio A; Plas, David R; Cunningham, John T 2021. Metabolic subtypes of clear cell renal cell carcinoma defined by tobacco smoking. Molecular & cellular oncology, 8 2, 1859917

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