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Photo of  Bryan C. Hambley, MD,MPH

Bryan C. Hambley, MD,MPH

Assistant Professor of Clinical

Internal Medicine | College of Medicine

  • Fellowship: Johns Hopkins Hospital (Hematology)
  • Fellowship: Johns Hopkins Hospital (Hematology)
  • Fellowship: Case Western Reserve University (Critical Care)
  • Chief Resident: Case Western Reserve University
  • Internship: Case Western Reserve University (Internal Medicine)
  • Master's Degree: Tulane University School of Public Health (Medicine and Health Systems Mangement)
  • Medical Degree: Tulane University School of Medicine
  • Bachelor's Degree: University of Notre Dame (Pre-Professional Studies and Political Science)
Board Certifications & Licenses

American Board of Internal Medicine (Critical Care Medicine) (Certification Date: 2020-12-15)
American Board of Internal Medicine (Hematology) (Certification Date: 2019-10-25)
American Board of Internal Medicine (Certification Date: 2015-08-11)


Critical Care Medicine
Internal Medicine

Contact Information

Clinical Interests

Critical Care Medicine

Hematology and Oncology


Acute Lymphocytic Leukemia

Acute Myeloid Leukemia


Castleman Disease

Chronic Lymphocytic Leukemia

Chronic Myelogenous Leukemia



M Protein


Mediastinal Adenopathy

Monoclonal gammopathy

Monoclonal protein


Mycosis Fugoides

Myelodysplastic Syndrome


Myeloproliferative Disorder


Plasma Cell Disorder

Plasminogen Activator Inhibitor 1

Polycythemia vera


Sideroblastic anemia

T-cell lymphoma

Peer Reviewed Publications

Coriu, Daniel; Dirzu, Noemi; Zimta, Alina-Andreea; Hambley, Bryan C; Liu, Xiaojing; Nemes, Laszlo; Ghiaur, Gabriel; Mahlangu, Johny; Tomuleasa, Ciprian 2022. Editorial: Modern Approaches to Hemophilia Management: Gene Therapy and Beyond. Frontiers in medicine, 9 , 859710

Murdock, H Moses; Kim, Haesook T; Denlinger, Nathan; Vachhani, Pankit; Hambley, Bryan; Manning, Bryan S; Gier, Shannon; Cho, Christina; Tsai, Harrison K; McCurdy, Shannon; Ho, Vincent T; Koreth, John; Soiffer, Robert J; Ritz, Jerome; Carroll, Martin P; Vasu, Sumithira; Perales, Miguel-Angel; Wang, Eunice S; Gondek, Lukasz P; Devine, Steven; Alyea, Edwin P; Lindsley, R Coleman; Gibson, Christopher J 2022. Impact of diagnostic genetics on remission MRD and transplantation outcomes in older patients with AML. Blood, 139 24, 3546-3557

VanDommelen, Kyle; Omer, Zulfa; Hambley, Bryan C; Stefaniuk, Catherine M 2022. Reversal of life-threatening bleeding with protamine sulfate in a patient with plasma cell leukemia. Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 33 7, 425-428

Hambley, Bryan C; Tomuleasa, Ciprian; Ghiaur, Gabriel 2021. Coagulopathy in Acute Promyelocytic Leukemia: Can We Go Beyond Supportive Care? Frontiers in medicine, 8 , 722614

Safi, Salahuddin; Shanbhag, Satish; Hambley, Bryan C; Merrill, Samuel A 2021. Systems controls are needed to reduce mistaken tests for hemophagocytic lymphohistiocytosis, results of a prospective quality-improvement cohort study. Medicine, 100 26, e26509

Trybula, Marcus; Wang, Diping; Baumann, Lauren; Pritts, Timothy A; Hambley, Bryan C 2021. Rhizopus microsporus typhlitis in a patient with acute myelogenous leukemia. Clinical case reports, 9 6, e04290

Alex Ambinder, Bryan Hambley, Satish Shanbhag, and Sam Merrill 2019. Ibrutinib-associated hemophagocytic lymphohistiocytosis: A case series from Johns Hopkins American Journal of Hematology, ,

Bryan Hambley, Kelly Norsworthy, Jagar Jasem, Jacquelyn Zimmerman et al. 2019. Fibrinogen consumption and use of heparin are risk factors for delayed bleeding during acute promyelocytic leukemia induction Leukemia Research, ,

Eric Gehrie et al. 2019. One-unit compared to two-unit platelet transfusions for adult oncology outpatients Vox Sanguinis, ,

Bryan Hambley, Paolo Caimi, and Basem William 2016. Bortezomib for the treatment of mantle cell lymphoma: an update Therapeutic Advances in Hematology, ,