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Laura Ngwenya, MD, PhD

Asst Professor - Clin

COM Neurosurgery Ngwenya Lab

Education/Credentials
  • Bachelor's Degree: Rutgers University
  • Doctor of Philosophy: Boston University
  • Medical Degree: Boston University
  • Neurological Surgery Residency: The Ohio State University
  • Neurotrauma and Neurocritical Care Fellowship: University of California San Francisco
Board Certifications & Licenses

American Board of Neurological Surgery (Certification Date: 11/02/2019)

Clinical Interest

Neurosurgery
N/A

Specialties

Neurological Surgery

Research Interests

Neurotrauma, Traumatic brain injury, Spinal injury, General Neurosurgery

Dr. Ngwenya has a clinical and research interest in neurotrauma, specifically, traumatic brain injury. Her clinical research involves identifying subsets ...

Contact Information
  • Medical Sciences Building
  • 231 Albert Sabin Way
  • Room 5251
  • Cincinnati, Ohio 45267
  • Office 513-558-0434
  • Email Laura.Ngwenya@uc.edu

Peer Reviewed Publications

Wright, James M; Gerges, Christina; Shammassian, Berje; Labak, Collin M; Herring, Eric Z; Miller, Benjamin; Alkhachroum, Ayham; Kottapally, Mohan; Huang Wright, Christina; Rodgers, Richard B; Sedney, Cara; Ngwenya, Laura B; Stippler, Martina; Sieg, Emily; Babu, Maya A; Hoffer, Alan; Hejal, Rana 2021. Prone Position Ventilation in Neurologically Ill Patients: A Systematic Review and Proposed Protocol. Critical care medicine, ,

Barhorst, Kinsey A; Alfawares, Yara; McGuire, Jennifer L; Danzer, Steve C; Hartings, Jed A; Ngwenya, Laura B 2020. Remote and Persistent Alterations in Glutamate Receptor Subunit Composition Induced by Spreading Depolarizations in Rat Brain. Cellular and molecular neurobiology, ,

Hartings, Jed A; Andaluz, Norberto; Bullock, M Ross; Hinzman, Jason M; Mathern, Bruce; Pahl, Clemens; Puccio, Ava; Shutter, Lori A; Strong, Anthony J; Vagal, Achala; Wilson, J Adam; Dreier, Jens P; Ngwenya, Laura B; Foreman, Brandon; Pahren, Laura; Lingsma, Hester; Okonkwo, David O 2020. Prognostic Value of Spreading Depolarizations in Patients With Severe Traumatic Brain Injury. JAMA neurology, 77 4, 489-499

Le, Diana T; Barhorst, Kinsey A; Castiglione, James; Yang, George L; Shah, Sanjit J; Harlan, Sarah S; Keegan, Shaun P; Jandarov, Roman A; Ngwenya, Laura B; Prestigiacomo, Charles J 2020. Blunt cerebrovascular injury in the geriatric population. Neurosurgical focus, 49 4, E10

Matur, Abhijith V; Ngwenya, Laura B; Prestigiacomo, Charles J 2020. The surgical history of head injury in motor vehicle collision. Journal of neurosurgery, , 1-7

Ngwenya, Laura B 2020. Commentary: Concussion Guidelines Step 2: Evidence for Subtype Classification. Neurosurgery, 86 1, E1

Porter, Zachary R; Mejia-Munne, Juan C; Krueger, Bryan M; Kosty, Jennifer A; Ngwenya, Laura B 2020. Sacral Rheumatoid Nodule: An Unusual Indication for Coccygectomy. Case reports in surgery, 2020 , 2757625

Rath, Kelly; Kreitzer, Natalie; Schlichter, Erika; Lopez, Omar; Ferioli, Simona; Ngwenya, Laura B; Foreman, Brandon 2020. The Experience of a Neurocritical Care Admission and Discharge for Patients and Their Families: A Qualitative Analysis. The Journal of neuroscience nursing : journal of the American Association of Neuroscience Nurses, 52 4, 179-185

Rhame, Katherine; Le, Diana; Horner, Amy; Thomas, Andrea; Foreman, Brandon P; Kreitzer, Natalie P; Ngwenya, Laura B 2020. Implementation of a Neurotrauma Hotline for post-hospital continuity of care. Acta neurologica Scandinavica, 141 4, 351-354

Rhame, Katherine; Le, Diana; Ventura, Amanda; Horner, Amy; Andaluz, Norberto; Miller, Christopher; Stolz, Uwe; Ngwenya, Laura B; Adeoye, Opeolu; Kreitzer, Natalie 2020. Management of the mild traumatic brain injured patient using a multidisciplinary observation unit protocol. The American journal of emergency medicine, ,

Robinson, David; Pyle, Logan; Foreman, Brandon; Ngwenya, Laura B; Adeoye, Opeolu; Woo, Daniel; Kreitzer, Natalie 2020. Factors Associated with Early versus Delayed Expansion of Acute Subdural Hematomas Initially Managed Conservatively. Journal of neurotrauma, ,

Shah, Sanjit; Yang, George L; Le, Diana T; Gerges, Christina; Wright, James M; Parr, Ann M; Cheng, Joseph S; Ngwenya, Laura B 2020. Examining the Emergency Medical Treatment and Active Labor Act: impact on telemedicine for neurotrauma. Neurosurgical focus, 49 5, E8

Burke, John F; Yue, John K; Ngwenya, Laura B; Winkler, Ethan A; Talbott, Jason F; Pan, Jonathan Z; Ferguson, Adam R; Beattie, Michael S; Bresnahan, Jacqueline C; Haefeli, Jenny; Whetstone, William D; Suen, Catherine G; Huang, Michael C; Manley, Geoffrey T; Tarapore, Phiroz E; Dhall, Sanjay S 2019. In Reply: Ultra-Early (<12 Hours) Surgery Correlates With Higher Rate of American Spinal Injury Association Impairment Scale Conversion After Cervical Spinal Cord Injury. Neurosurgery, 85 2, E401-E402

Burke, John F; Yue, John K; Ngwenya, Laura B; Winkler, Ethan A; Talbott, Jason F; Pan, Jonathan Z; Ferguson, Adam R; Beattie, Michael S; Bresnahan, Jacqueline C; Haefeli, Jenny; Whetstone, William D; Suen, Catherine G; Huang, Michael C; Manley, Geoffrey T; Tarapore, Phiroz E; Dhall, Sanjay S 2019. Ultra-Early (<12 Hours) Surgery Correlates With Higher Rate of American Spinal Injury Association Impairment Scale Conversion After Cervical Spinal Cord Injury. Neurosurgery, 85 2, 199-203

Dossani, Rimal H; Terrell, Danielle; Kosty, Jennifer A; Ross, Robert C; Demand, Audrey; Wild, Elizabeth; Peterson, Racheal; Ngwenya, Laura B; Benzil, Deborah L; Notarianni, Christina 2019. Gender disparities in academic rank achievement in neurosurgery: a critical assessment. Journal of neurosurgery, , 1-6

Foreman, Brandon; Cass, Daryn; Forbes, Jonathan; Ngwenya, Laura B 2019. A Bedside, Single Burr Hole Approach to Multimodality Monitoring in Severe Brain Injury. Journal of visualized experiments : JoVE, 145,

Foreman, Brandon; Ngwenya, Laura B 2019. The Sustainability of Applied Intracranial Multimodality Neuromonitoring after Severe Brain Injury. World neurosurgery, ,

Khalid, Fatima; Yang, George L; McGuire, Jennifer L; Robson, Matthew J; Foreman, Brandon; Ngwenya, Laura B; Lorenz, John N 2019. Autonomic dysfunction following traumatic brain injury: translational insights. Neurosurgical focus, 47 5, E8

Lee, Hyunjo; Mizrahi, Moshe A; Hartings, Jed A; Sharma, Sameer; Pahren, Laura; Ngwenya, Laura B; Moseley, Brian D; Privitera, Michael; Tortella, Frank C; Foreman, Brandon 2019. Continuous Electroencephalography After Moderate to Severe Traumatic Brain Injury. Critical care medicine, 47 4, 574-582

McGuire, Jennifer L; Correll, Erika A; Lowery, Alexandra C; Rhame, Katherine; Anwar, Fatima N; McCullumsmith, Robert E; Ngwenya, Laura B 2019. Pioglitazone improves working memory performance when administered in chronic TBI. Neurobiology of disease, 132 , 104611

McGuire, Jennifer L; Ngwenya, Laura B; McCullumsmith, Robert E 2019. Neurotransmitter changes after traumatic brain injury: an update for new treatment strategies. Molecular psychiatry, 24 7, 995-1012

Foreman, Brandon; Ngwenya, Laura B; Stoddard, Erica; Hinzman, Jason M; Andaluz, Norberto; Hartings, Jed A 2018. Safety and Reliability of Bedside, Single Burr Hole Technique for Intracranial Multimodality Monitoring in Severe Traumatic Brain Injury. Neurocritical care, ,

Hartings, Jed A; Ngwenya, Laura B; Carroll, Christopher P; Foreman, Brandon 2018. Letter to the Editor. Ketamine sedation for the suppression of spreading depolarizations. Journal of neurosurgery, , 1-2

Hartings, Jed A; Ngwenya, Laura B; Watanabe, Tomas; Foreman, Brandon 2018. Commentary: Detecting Cortical Spreading Depolarization with Full Band Scalp Electroencephalography: An Illusion? Frontiers in systems neuroscience, 12 , 19

McGuire, Jennifer L; DePasquale, Erica A K; Watanabe, Miki; Anwar, Fatima; Ngwenya, Laura B; Atluri, Gowtham; Romick-Rosendale, Lindsey E; McCullumsmith, Robert E; Evanson, Nathan K 2018. Chronic Dysregulation of Cortical and Subcortical Metabolism After Experimental Traumatic Brain Injury. Molecular neurobiology, ,

Ngwenya, Laura B; Danzer, Steve C 2018. Impact of Traumatic Brain Injury on Neurogenesis. Frontiers in neuroscience, 12 , 1014

Ngwenya, Laura B; Gardner, Raquel C; Yue, John K; Burke, John F; Ferguson, Adam R; Huang, Michael C; Winkler, Ethan A; Pirracchio, Romain; Satris, Gabriela G; Yuh, Esther L; Mukherjee, Pratik; Valadka, Alex B; Okonkwo, David O; Manley, Geoffrey T 2018. Concordance of common data elements for assessment of subjective cognitive complaints after mild-traumatic brain injury: a TRACK-TBI Pilot Study. Brain injury, 32 9, 1071-1078

Ngwenya, Laura B; Mazumder, Sarmistha; Porter, Zachary R; Minnema, Amy; Oswald, Duane J; Farhadi, H Francis 2018. Implantation of Neuronal Stem Cells Enhances Object Recognition without Increasing Neurogenesis after Lateral Fluid Percussion Injury in Mice. Stem cells international, 2018 , 4209821

Estrada, Larissa I; Robinson, Amy A; Amaral, Ana C; Giannaris, Eustathia L; Heyworth, Nadine C; Mortazavi, Farzad; Ngwenya, Laura B; Roberts, Debra E; Cabral, Howard J; Killiany, Ronald J; Rosene, Douglas L 2017. Evaluation of Long-Term Cryostorage of Brain Tissue Sections for Quantitative Histochemistry. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 65 3, 153-171

Martin, Grace E; Carroll, Christopher P; Plummer, Zach J; Millar, D A; Pritts, Timothy A; Makley, Amy T; Joseph, Bellal A; Ngwenya, Laura B; Goodman, Michael D 2017. Safety and Efficacy of Brain Injury Guidelines at a Level III Trauma Center. The journal of trauma and acute care surgery, ,

Ngwenya, Laura B; Suen, Catherine G; Tarapore, Phiroz E; Manley, Geoffrey T; Huang, Michael C 2017. Safety and cost efficiency of a restrictive transfusion protocol in patients with traumatic brain injury. Journal of neurosurgery, , 1-8

Yue, John K; Burke, John F; Upadhyayula, Pavan S; Winkler, Ethan A; Deng, Hansen; Robinson, Caitlin K; Pirracchio, Romain; Suen, Catherine G; Sharma, Sourabh; Ferguson, Adam R; Ngwenya, Laura B; Stein, Murray B; Manley, Geoffrey T; Tarapore, Phiroz E 2017. Selective Serotonin Reuptake Inhibitors for Treating Neurocognitive and Neuropsychiatric Disorders Following Traumatic Brain Injury: An Evaluation of Current Evidence. Brain sciences, 7 8,

Yue, John K; Ngwenya, Laura B; Upadhyayula, Pavan S; Deng, Hansen; Winkler, Ethan A; Burke, John F; Lee, Young M; Robinson, Caitlin K; Ferguson, Adam R; Lingsma, Hester F; Cnossen, Maryse C; Pirracchio, Romain; Korley, Frederick K; Vassar, Mary J; Yuh, Esther L; Mukherjee, Pratik; Gordon, Wayne A; Valadka, Alex B; Okonkwo, David O; Manley, Geoffrey T 2017. Emergency department blood alcohol level associates with injury factors and six-month outcome after uncomplicated mild traumatic brain injury. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, ,

Yue, John K; Robinson, Caitlin K; Winkler, Ethan A; Upadhyayula, Pavan S; Burke, John F; Pirracchio, Romain; Suen, Catherine G; Deng, Hansen; Ngwenya, Laura B; Dhall, Sanjay S; Manley, Geoffrey T; Tarapore, Phiroz E 2017. Circadian variability of the initial Glasgow Coma Scale score in traumatic brain injury patients. Neurobiology of sleep and circadian rhythms, 2 , 85-93

Burke, John Frederick; Yue, John K; Ngwenya, Laura Benjamin; Winkler, Ethan A; Talbott, Jason; Pan, Jonathan; Ferguson, Adam; Beattie, Michael; Bresnahan, Jacqueline; Haefeli, Jenny; Whetstone, William; Suen, Catherine; Huang, Michael C; Manley, Geoffrey T; Tarapore, Phiroz E; Dhall, Sanjay S 2016. 182?Ultra-Early (<12 Hours) Decompression Improves Recovery After Spinal Cord Injury Compared to Early (12-24 Hours) Decompression. Neurosurgery, 63 Suppl 1 , 172

Ngwenya, Laura B; Burke, John F; Manley, Geoffrey T 2016. Brain Tissue Oxygen Monitoring and the Intersection of Brain and Lung: A Comprehensive Review. Respiratory care, 61 9, 1232-44

Ngwenya, Laura B; Prevedello, Luciano M; Youssef, Patrick P 2016. Concomitant epidural and subdural spinal abscess: a case report. The spine journal : official journal of the North American Spine Society, 16 4, e275-82

Ngwenya, Laura B; Heyworth, Nadine C; Shwe, Yamin; Moore, Tara L; Rosene, Douglas L 2015. Age-related changes in dentate gyrus cell numbers, neurogenesis, and associations with cognitive impairments in the rhesus monkey. Frontiers in systems neuroscience, 9 , 102

Ngwenya, Laura B; Chiocca, E Antonio 2013. Editorial: postoperative ischemia. Journal of neurosurgery, 118 4, 799-800; discussion

Ngwenya, Laura B; Chiocca, E Antonio 2012. Editorial: meningioma and radiotherapy. Journal of neurosurgery, 117 4, 666-8

Ngwenya, Laura B; Chiocca, E Antonio 2011. Extent of resection. Journal of neurosurgery, 115 1, 1-2; discussion 2

Ngwenya, Laura B; Rosene, Douglas L; Peters, Alan 2008. An ultrastructural characterization of the newly generated cells in the adult monkey dentate gyrus. Hippocampus, 18 2, 210-20

Ngwenya, Laura B; Peters, Alan; Rosene, Douglas L 2006. Maturational sequence of newly generated neurons in the dentate gyrus of the young adult rhesus monkey. The Journal of comparative neurology, 498 2, 204-16

Ngwenya, Laura B; Peters, Alan; Rosene, Douglas L 2005. Light and electron microscopic immunohistochemical detection of bromodeoxyuridine-labeled cells in the brain: different fixation and processing protocols. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 53 7, 821-32

Kreitzer, Natalie; Ancona, Rachel; McCullumsmith, Cheryl; Kurowski, Brad G; Foreman, Brandon; Ngwenya, Laura B; Adeoye, Opeolu . The Effect of Antidepressants on Depression After Traumatic Brain Injury: A Meta-analysis. The Journal of head trauma rehabilitation, 34 3, E47-E54

Kreitzer, Natalie; Bakas, Tamilyn; Kurowski, Brad; Lindsell, Christopher J; Ferioli, Simona; Foreman, Brandon; Ngwenya, Laura B; Thomas, Stephanie; Keegan, Sara; Adeoye, Opeolu . The Experience of Caregivers Following a Moderate to Severe Traumatic Brain Injury Requiring ICU Admission. The Journal of head trauma rehabilitation, 35 3, E299-E309

Ngwenya, Laura B; Chiocca, E Antonio . Do meningioma patients benefit from antiepileptic drug treatment? World neurosurgery, 79 3-4, 433-4

Ngwenya, Laura B; Chiocca, E Antonio . Treatment for paragangliomas: passing the test of time. World neurosurgery, 77 5-6, 639-41