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Eric Hugo, PhD

Education/Credentials
  • B.Sc.: Northern Kentucky University
  • M.S.: The Ohio State University
  • Ph.D.: The Ohio State University
Contact Information

Peer Reviewed Publications

Hugo, Estefanía A; Cassels, Bruce K; Fierro, Angélica 2017. Functional roles of T3.37 and S5.46 in the activation mechanism of the dopamine D1 receptor. Journal of molecular modeling, 23 4, 142

Ben-Jonathan N, Hugo ER 2016. Bisphenols Come in Different Flavors: Is "S" Better Than "A"? Endocrinology, 157 , 1321-1323

Borcherding, D C; Tong, W; Hugo, E R; Barnard, D F; Fox, S; LaSance, K; Shaughnessy, E; Ben-Jonathan, N 2016. Expression and therapeutic targeting of dopamine receptor-1 (D1R) in breast cancer. Oncogene, 35 24, 3103-13

Ben-Jonathan, Nira; Hugo, Eric 2015. Prolactin (PRL) in adipose tissue: regulation and functions. Advances in experimental medicine and biology, 846 , 1-35

Tuttle, Traci R; Hugo, Eric R; Tong, Wilson S; Ben-Jonathan, Nira 2014. Placental lactogen is expressed but is not translated into protein in breast cancer. PloS one, 9 1, e87325

Lo, Yuan-Hung; Ho, Po-Chun; Chen, Min-Shan; Hugo, Eric; Ben-Jonathan, Nira; Wang, Shao-Chun 2013. Phosphorylation at tyrosine 114 of Proliferating Cell Nuclear Antigen (PCNA) is required for adipogenesis in response to high fat diet. Biochemical and biophysical research communications, 430 1, 43-8

Villarroel, Pia; Reyes, Marcela; Fuentes, Cecilia; Segovia, María Pia; Tobar, Nicolás; Villalobos, Elisa; Martínez, Jorge; Hugo, Eric; Ben-Jonathan, Nira; Cifuentes, Mariana 2013. Adipogenic effect of calcium sensing receptor activation. Molecular and cellular biochemistry, 384 1-2, 139-45

Cifuentes, Mariana; Fuentes, Cecilia; Tobar, Nicolas; Acevedo, Ingrid; Villalobos, Elisa; Hugo, Eric; Ben-Jonathan, Nira; Reyes, Marcela 2012. Calcium sensing receptor activation elevates proinflammatory factor expression in human adipose cells and adipose tissue. Molecular and cellular endocrinology, 361 1-2, 24-30

Kendig, Eric L; Buesing, Dana R; Christie, Susie M; Cookman, Clifford J; Gear, Robin B; Hugo, Eric R; Kasper, Susan N; Kendziorski, Jessica A; Ungi, Kevin R; Williams, Karin; Belcher, Scott M 2012. Estrogen-Like Disruptive Effects of Dietary Exposure to Bisphenol A or 17?-Ethinyl Estradiol in CD1 Mice. International journal of toxicology, 31 6, 537-50

Borcherding, Dana C; Hugo, Eric R; Idelman, Gila; De Silva, Anuradha; Richtand, Nathan W; Loftus, Jean; Ben-Jonathan, Nira 2011. Dopamine receptors in human adipocytes: expression and functions. PloS one, 6 9, e25537

Jacobson, Eric M; Hugo, Eric R; Borcherding, Dana C; Ben-Jonathan, Nira 2011. Prolactin in breast and prostate cancer: molecular and genetic perspectives. Discovery medicine, 11 59, 315-24

Cifuentes, Mariana; Fuentes, Cecilia; Mattar, Pamela; Tobar, Nicolas; Hugo, Eric; Ben-Jonathan, Nira; Rojas, Cecilia; Martínez, Jorge 2010. Obesity-associated proinflammatory cytokines increase calcium sensing receptor (CaSR) protein expression in primary human adipocytes and LS14 human adipose cell line. Archives of biochemistry and biophysics, 500 2, 151-6

Jacobson, Eric M; Hugo, Eric R; Tuttle, Traci R; Papoian, Ruben; Ben-Jonathan, Nira 2010. Unexploited therapies in breast and prostate cancer: blockade of the prolactin receptor. Trends in endocrinology and metabolism: TEM, 21 11, 691-8

Ben-Jonathan, N.; Hugo, E. R.; Brandebourg, T. D. 2009. Effects of bisphenol A on adipokine release from human adipose tissue: Implications for the metabolic syndrome Mol Cell Endocrinol, 304 1-2 , 49-54

Ben-Jonathan, Nira; Hugo, Eric R; Brandebourg, Terry D 2009. Effects of bisphenol A on adipokine release from human adipose tissue: Implications for the metabolic syndrome. Molecular and cellular endocrinology, 304 1-2, 49-54

Hugo, E. R.; Borcherding, D. C.; Gersin, K. S.; Loftus, J.; Ben-Jonathan, N. 2008. Prolactin release by adipose explants, primary adipocytes, and LS14 adipocytes J Clin Endocrinol Metab, 93 10 , 4006-12

Hugo, E. R.; Brandebourg, T. D.; Woo, J. G.; Loftus, J.; Alexander, J. W.; Ben-Jonathan, N. 2008. Bisphenol A at environmentally relevant doses inhibits adiponectin release from human adipose tissue explants and adipocytes Environ Health Perspect, 116 12 , 1642-7

Hugo, Eric R; Borcherding, Dana C; Gersin, Keith S; Loftus, Jean; Ben-Jonathan, Nira 2008. Prolactin release by adipose explants, primary adipocytes, and LS14 adipocytes. The Journal of clinical endocrinology and metabolism, 93 10, 4006-12

Hugo, Eric R; Brandebourg, Terry D; Woo, Jessica G; Loftus, Jean; Alexander, J Wesley; Ben-Jonathan, Nira 2008. Bisphenol A at environmentally relevant doses inhibits adiponectin release from human adipose tissue explants and adipocytes. Environmental health perspectives, 116 12, 1642-7

LaPensee, C. R.; Hugo, E. R.; Ben-Jonathan, N. 2008. Insulin stimulates interleukin-6 expression and release in LS14 human adipocytes through multiple signaling pathways Endocrinology, 149 11 , 5415-22

LaPensee, Christopher R; Hugo, Eric R; Ben-Jonathan, Nira 2008. Insulin stimulates interleukin-6 expression and release in LS14 human adipocytes through multiple signaling pathways. Endocrinology, 149 11, 5415-22

Brandebourg, T.; Hugo, E.; Ben-Jonathan, N. 2007. Adipocyte prolactin: regulation of release and putative functions Diabetes Obes Metab, 9 4 , 464-76

Brandebourg, T; Hugo, E; Ben-Jonathan, N 2007. Adipocyte prolactin: regulation of release and putative functions. Diabetes, obesity & metabolism, 9 4, 464-76

LaPensee, E. W.; Reddy, S. P.; Hugo, E. R.; Schwemberger, S. J.; Ben-Jonathan, N. 2007. LS14 cells: a model for chemoresistance in liposarcoma Cancer Biol Ther, 6 4 , 519-24

LaPensee, Elizabeth W; Reddy, Shamantha P; Hugo, Eric R; Schwemberger, Sandy J; Ben-Jonathan, Nira 2007. LS14 cells: a model for chemoresistance in liposarcoma. Cancer biology & therapy, 6 4, 519-24

Ben-Jonathan, N.; Hugo, E. R.; Brandebourg, T. D.; LaPensee, C. R. 2006. Focus on prolactin as a metabolic hormone Trends Endocrinol Metab, 17 3 , 110-6

Ben-Jonathan, Nira; Hugo, Eric R; Brandebourg, Terry D; LaPensee, Christopher R 2006. Focus on prolactin as a metabolic hormone. Trends in endocrinology and metabolism: TEM, 17 3, 110-6

Hugo, E. R.; Brandebourg, T. D.; Comstock, C. E.; Gersin, K. S.; Sussman, J. J.; Ben-Jonathan, N. 2006. LS14: a novel human adipocyte cell line that produces prolactin Endocrinology, 147 1 , 306-13

Hugo, Eric R; Brandebourg, Terry D; Comstock, Clay E S; Gersin, Keith S; Sussman, Jeffrey J; Ben-Jonathan, Nira 2006. LS14: a novel human adipocyte cell line that produces prolactin. Endocrinology, 147 1, 306-13

LaPensee, C. R.; Horseman, N. D.; Tso, P.; Brandebourg, T. D.; Hugo, E. R.; Ben-Jonathan, N. 2006. The prolactin-deficient mouse has an unaltered metabolic phenotype Endocrinology, 147 10 , 4638-45

LaPensee, Christopher R; Horseman, Nelson D; Tso, Patrick; Brandebourg, Terry D; Hugo, Eric R; Ben-Jonathan, Nira 2006. The prolactin-deficient mouse has an unaltered metabolic phenotype. Endocrinology, 147 10, 4638-45

McFarland-Mancini, M.; Hugo, E.; Loftus, J.; Ben-Jonathan, N. 2006. Induction of prolactin expression and release in human preadipocytes by cAMP activating ligands Biochem Biophys Res Commun, 344 1 , 9-16

McFarland-Mancini, Molly; Hugo, Eric; Loftus, Jean; Ben-Jonathan, Nira 2006. Induction of prolactin expression and release in human preadipocytes by cAMP activating ligands. Biochemical and biophysical research communications, 344 1, 9-16

Clark, A C; Hugo, E; Frieden, C 1996. Determination of regions in the dihydrofolate reductase structure that interact with the molecular chaperonin GroEL. Biochemistry, 35 18, 5893-901

Clark, A. C.; Hugo, E.; Frieden, C. 1996. Determination of regions in the dihydrofolate reductase structure that interact with the molecular chaperonin GroEL Biochemistry, 35 18 , 5893-901

Hugo, E R; Byers, T J 1993. S-adenosyl-L-methionine decarboxylase of Acanthamoeba castellanii (Neff): purification and properties. The Biochemical journal, 295 ( Pt 1) , 203-9

Hugo, E. R.; Byers, T. J. 1993. S-adenosyl-L-methionine decarboxylase of Acanthamoeba castellanii (Neff): purification and properties Biochem J, 295 ( Pt 1) 18 , 203-9

Byers, T. J.; Kim, B. G.; King, L. E.; Hugo, E. R. 1991. Molecular aspects of the cell cycle and encystment of Acanthamoeba Rev Infect Dis, 13 Suppl 5 3 , S373-84

Hugo, E R; McLaughlin, W R; Oh, K H; Tuovinen, O H 1991. Quantitative enumeration of acanthamoeba for evaluation of cyst inactivation in contact lens care solutions. Investigative ophthalmology & visual science, 32 3, 655-7

Hugo, E. R.; McLaughlin, W. R.; Oh, K. H.; Tuovinen, O. H. 1991. Quantitative enumeration of acanthamoeba for evaluation of cyst inactivation in contact lens care solutions Invest Ophthalmol Vis Sci, 32 3 , 655-7

Byers, T. J.; Hugo, E. R.; Stewart, V. J. 1990. Genes of Acanthamoeba: DNA, RNA and protein sequences (a review) J Protozool, 37 4 , 17S-25S

Byers, T J; Hugo, E R; Stewart, V J . Genes of Acanthamoeba: DNA, RNA and protein sequences (a review). The Journal of protozoology, 37 4, 17S-25S

Byers, T J; Kim, B G; King, L E; Hugo, E R . Molecular aspects of the cell cycle and encystment of Acanthamoeba. Reviews of infectious diseases, 13 Suppl 5 , S373-84

Abstract Publications

Carter, JH, Richmond, R, Hugo, E, Chen, T, Bhatt, TR, Douglass, L, Nesnow, S Deangelo, A. 2002. Apoptosis and proliferation during dichloroacetic acid (DCA) induced hepatocellular carcinogenesis in the F344 male rat. Proceedings of the American Association for Cancer Research Annual Meeting , 43 , 1046


Carter JH, Hugo ER, Douglass LE, Richmond RE, Hurst BM, DeAngelo AB, and Nesnow AB. 2001. Dichloroacetic Acid (DCA) Inhibits Proliferation and Apoptosis in Normal Hepatocytes of Male F344 Rats. Proc. Amer. Assoc. Cancer Res. , 42 , 602


Carter, JH, Hugo ER, Holden T, Porco M and Fritz D. 2001. Cysteine Protease and Cysteine Protease Inhibitor Expression in Prostate Cancer Cell Lines. Proc. Amer. Assoc. Cancer Res. , 42 , 403


Carter, JH, Hugo, ER Douglass, LE, Richmond, RE Hurst, BM, DeAngelo, AB and Nesnow, S. 2001. Dichloroacetic acid (DCA) inhibits proliferation and apoptosis in normal hepatocytes of male F344 rats. Proceedings of the American Association for Cancer Research Annual Meeting , 42 , 602


Holden, T, Fritz, DW, Porco, MA, Hurst, BM, Hugo, ER, and Carter, JH. 2000. The Development and Characterization of a Human Peritoneal-derived Malignant Mesothelioma Cell Line. Proc KY Acad. Sci, ,