2024

Cissé, Ousmane H; Curran, Shelly J; Folco, H Diego; Liu, Yueqin; Bishop, Lisa; Wang, Honghui; Fischer, Elizabeth R; Davis, A Sally; Combs, Christian; Thapar, Sabrina; Dekker, John P; Grewal, Shiv; Cushion, Melanie; Ma, Liang; Kovacs, Joseph A 2024. Regional centromere configuration in the fungal pathogens of the Pneumocystis genus. mBio, , e0318523

Sayson, Steven G; Ashbaugh, Alan; Porollo, Aleksey; Cushion, Melanie T 2024. Pneumocystis murina Promotes Inflammasome Formation and NETosis during Pneumocystis Pneumonia. bioRxiv : the preprint server for biology, ,

Sayson, Steven G; Ashbaugh, Alan; Cushion, Melanie T 2024. Extracellular vesicles from Pneumocystis carinii-infected rats impair fungal viability but are dispensable for macrophage functions. Microbiology spectrum, 12 2, e0365323

2023

Cissé, Ousmane H; Curran, Shelly; Folco, H Diego; Liu, Yueqin; Bishop, Lisa; Wang, Honghui; Fischer, Elizabeth R; Davis, A Sally; Babb-Biernacki, Spenser; Doyle, Vinson P; Richards, Jonathan K; Hassan, Sergio A; Dekker, John P; Khil, Pavel P; Brenchley, Jason M; Grewal, Shiv; Cushion, Melanie; Ma, Liang; Kovacs, Joseph A 2023. The Host Adapted Fungal Pathogens of Pneumocystis Genus Utilize Genic Regional Centromeres. bioRxiv : the preprint server for biology, ,

Wiederhold, Nathan P; Patterson, Thomas F; Rebholz, Sandra; Brennan, James; Patton, Thomas; Barrett, John; Boal, Connell W C; Ehrensberger, Monika; Boyle, Ryan; Cushion, Melanie T 2023. Erratum for Wiederhold et al., "The Antifungal and Anti-Pneumocystis Activities of the Novel Compound A3IS (Mycosinate)". Antimicrobial agents and chemotherapy, 67 2, e0147522

Meier, Caroline S; Pagni, Marco; Richard, Sophie; Mühlethaler, Konrad; Almeida, João M G C F; Nevez, Gilles; Cushion, Melanie T; Calderón, Enrique J; Hauser, Philippe M 2023. Publisher Correction: Fungal antigenic variation using mosaicism and reassortment of subtelomeric genes' repertoires. Nature communications, 14 1, 7928

Meier, Caroline S; Pagni, Marco; Richard, Sophie; Mühlethaler, Konrad; Almeida, João M G C F; Nevez, Gilles; Cushion, Melanie T; Calderón, Enrique J; Hauser, Philippe M 2023. Fungal antigenic variation using mosaicism and reassortment of subtelomeric genes' repertoires. Nature communications, 14 1, 7026

Sayson, Steven G; Ashbaugh, Alan; Cushion, Melanie T 2023. Extracellular Vesicles from Pneumocystis carinii -Infected Rats Impair Fungal Viability but are Dispensable for Macrophage Functions. bioRxiv : the preprint server for biology, ,

2022

Cushion, Melanie T; Ashbaugh, Alan; Sayson, Steven G; Mosley, Christopher; Hauser, Philippe M 2022. Anidulafungin Treatment Blocks the Sexual Cycle of Pneumocystis murina and Prevents Growth and Survival without Rescue by an Alternative Mode of Replication. Microbiology spectrum, 10 6, e0290622

Macioce-Tisdale, Nikeya L; Ashbaugh, Alan; Hendrix, Keeley; Collins, Margaret S; Porollo, Aleksey; Cushion, Melanie T 2022. The Effects of Sex and Strain on Pneumocystis murina Fungal Burdens in Mice. Journal of fungi (Basel, Switzerland), 8 10,

Wiederhold, Nathan P; Patterson, Thomas F; Rebholz, Sandra; Boal, Connell W C; Ehrensberger, Monika; Boyle, Ryan; Cushion, Melanie T 2022. The Antifungal and Anti-Pneumocystis Activities of the Novel Compound A3IS (Mycosinate). Antimicrobial agents and chemotherapy, 66 8, e0052122

2021

Cushion, Melanie T; Ashbaugh, Alan 2021. The Long-Acting Echinocandin, Rezafungin, Prevents Pneumocystis Pneumonia and Eliminates Pneumocystis from the Lungs in Prophylaxis and Murine Treatment Models. Journal of fungi (Basel, Switzerland), 7 9,

Miesel, Lynn; Cushion, Melanie T; Ashbaugh, Alan; Lopez, Santiago R; Ong, Voon 2021. Efficacy of Rezafungin in Prophylactic Mouse Models of Invasive Candidiasis, Aspergillosis, and Pneumocystis Pneumonia. Antimicrobial agents and chemotherapy, 65 3,

Cushion, Melanie T; Tisdale-Macioce, Nikeya; Sayson, Steven G; Porollo, Aleksey 2021. The Persistent Challenge of Pneumocystis Growth Outside the Mammalian Lung: Past and Future Approaches. Frontiers in microbiology, 12 , 681474

Cissé, Ousmane H; Ma, Liang; Dekker, John P; Khil, Pavel P; Youn, Jung-Ho; Brenchley, Jason M; Blair, Robert; Pahar, Bapi; Chabé, Magali; Van Rompay, Koen K A; Keesler, Rebekah; Sukura, Antti; Hirsch, Vanessa; Kutty, Geetha; Liu, Yueqin; Peng, Li; Chen, Jie; Song, Jun; Weissenbacher-Lang, Christiane; Xu, Jie; Upham, Nathan S; Stajich, Jason E; Cuomo, Christina A; Cushion, Melanie T; Kovacs, Joseph A 2021. Genomic insights into the host specific adaptation of the Pneumocystis genus. Communications biology, 4 1, 305

Tisdale-Macioce, Nikeya; Green, Jenna; Perl, Anne-Karina T; Ashbaugh, Alan; Wiederhold, Nathan P; Patterson, Thomas F; Cushion, Melanie T 2021. The Promise of Lung Organoids for Growth and Investigation of Pneumocystis Species. Frontiers in fungal biology, 2 , 740845

2020

Ma, Liang; Chen, Zehua; Huang, Da Wei; Cissé, Ousmane H; Rothenburger, Jamie L; Latinne, Alice; Bishop, Lisa; Blair, Robert; Brenchley, Jason M; Chabé, Magali; Deng, Xilong; Hirsch, Vanessa; Keesler, Rebekah; Kutty, Geetha; Liu, Yueqin; Margolis, Daniel; Morand, Serge; Pahar, Bapi; Peng, Li; Van Rompay, Koen K A; Song, Xiaohong; Song, Jun; Sukura, Antti; Thapar, Sabrina; Wang, Honghui; Weissenbacher-Lang, Christiane; Xu, Jie; Lee, Chao-Hung; Jardine, Claire; Lempicki, Richard A; Cushion, Melanie T; Cuomo, Christina A; Kovacs, Joseph A 2020. Diversity and Complexity of the Large Surface Protein Family in the Compacted Genomes of Multiple Pneumocystis Species. mBio, 11 2,

Cushion, Melanie T; Kumar, Parag; Lu, Ruying; Ashbaugh, Alan; Adeojo, Lilian W; Alfaro, Raul; Mannino, Raphael; Tramont, Edmund; Kovacs, Joseph A 2020. A Novel Encochleated Formulation Improves Atovaquone Activity in a Murine Model of Pneumocystis Pneumonia. The Journal of infectious diseases, ,

2019

Luraschi, A; Richard, S; Almeida, J M G C F; Pagni, M; Cushion, M T; Hauser, P M 2019. Expression and Immunostaining Analyses Suggest that Pneumocystis Primary Homothallism Involves Trophic Cells Displaying Both Plus and Minus Pheromone Receptors. mBio, 10 4,

Liu, Guan-Sheng; Ballweg, Richard; Ashbaugh, Alan; Zhang, Yin; Facciolo, Joseph; Cushion, Melanie T; Zhang, Tongli 2019. Correction to: A quantitative systems pharmacology (QSP) model for Pneumocystis treatment in mice. BMC systems biology, 13 1, 40

2018

Hauser, Philippe M; Cushion, Melanie T 2018. Is sex necessary for the proliferation and transmission of Pneumocystis? PLoS pathogens, 14 12, e1007409

Cushion, Melanie T; Limper, Andrew H; Porollo, Aleksey; Saper, Vivian E; Sinai, Anthony P; Weiss, Louis M 2018. The 14th International Workshops on Opportunistic Protists (IWOP 14). The Journal of eukaryotic microbiology, 65 6, 934-939

Gomes, Ana; Ferraz, Ricardo; Ficker, Lauren; Collins, Margaret S; Prudêncio, Cristina; Cushion, Melanie T; Teixeira, Cátia; Gomes, Paula 2018. Chloroquine Analogues as Leads against Pneumocystis Lung Pathogens. Antimicrobial agents and chemotherapy, 62 11,

Cushion, Melanie T 2018. Reply to Nevez et al., "The Fascinating Echinocandin-Treated Mouse Model of Pneumocystis murina To Understand Pneumocystis jirovecii". Antimicrobial agents and chemotherapy, 62 8,

Liu, Guan-Sheng; Ballweg, Richard; Ashbaugh, Alan; Zhang, Yin; Facciolo, Joseph; Cushion, Melanie T; Zhang, Tongli 2018. A quantitative systems pharmacology (QSP) model for Pneumocystis treatment in mice. BMC systems biology, 12 1, 77

Lazzarini, Cristina; Haranahalli, Krupanandan; Rieger, Robert; Ananthula, Hari Krishna; Desai, Pankaj B; Ashbaugh, Alan; Linke, Michael J; Cushion, Melanie T; Ruzsicska, Bela; Haley, John; Ojima, Iwao; Del Poeta, Maurizio 2018. Acylhydrazones as Antifungal Agents Targeting the Synthesis of Fungal Sphingolipids. Antimicrobial agents and chemotherapy, 62 5,

Cushion, Melanie T; Ashbaugh, Alan; Hendrix, Keeley; Linke, Michael J; Tisdale, Nikeya; Sayson, Steven G; Porollo, Aleksey 2018. Gene Expression of Pneumocystis murina after Treatment with Anidulafungin Results in Strong Signals for Sexual Reproduction, Cell Wall Integrity, and Cell Cycle Arrest, Indicating a Requirement for Ascus Formation for Proliferation. Antimicrobial agents and chemotherapy, 62 5,

Mor, Visesato; Rella, Antonella; Farnoud, Amir M; Singh, Ashutosh; Munshi, Mansa; Bryan, Arielle; Naseem, Shamoon; Konopka, James B; Ojima, Iwao; Bullesbach, Erika; Ashbaugh, Alan; Linke, Michael J; Cushion, Melanie; Collins, Margaret; Ananthula, Hari Krishna; Sallans, Larry; Desai, Pankaj B; Wiederhold, Nathan P; Fothergill, Annette W; Kirkpatrick, William R; Patterson, Thomas; Wong, Lai Hong; Sinha, Sunita; Giaever, Guri; Nislow, Corey; Flaherty, Patrick; Pan, Xuewen; Cesar, Gabriele Vargas; de Melo Tavares, Patricia; Frases, Susana; Miranda, Kildare; Rodrigues, Marcio L; Luberto, Chiara; Nimrichter, Leonardo; Del Poeta, Maurizio 2018. Erratum for Mor et al., "Identification of a New Class of Antifungals Targeting the Synthesis of Fungal Sphingolipids". mBio, 9 2,

2017

Maciejewska, D; Zabinski, J; Rezler, M; Kazmierczak, P; Collins, M S; Ficker, L; Cushion, M T 2017. Correction: Development of highly active anti-Pneumocystis bisbenzamidines: insight into the influence of selected substituents on the in vitro activity. MedChemComm, 8 11, 2164

Maciejewska, D; Zabinski, J; Rezler, M; Kazmierczak, P; Collins, M S; Ficker, L; Cushion, M T 2017. Development of highly active anti-Pneumocystis bisbenzamidines: insight into the influence of selected substituents on the in vitro activity. MedChemComm, 8 10, 2003-2011

2016

Cushion, Melanie T; Collins, Margaret S; Sesterhenn, Thomas; Porollo, Aleksey; Vadukoot, Anish Kizhakkekkara; Merino, Edward J 2016. Functional Characterization of Pneumocystis carinii Inositol Transporter 1. mBio, 7 6,

Baker, Frazier N; Cushion, Melanie T; Porollo, Aleksey 2016. A Quantitative Model to Estimate Drug Resistance in Pathogens. Journal of fungi (Basel, Switzerland), 2 4,

Koselny, Kristy; Green, Julianne; DiDone, Louis; Halterman, Justin P; Fothergill, Annette W; Wiederhold, Nathan P; Patterson, Thomas F; Cushion, Melanie T; Rappelye, Chad; Wellington, Melanie; Krysan, Damian J 2016. The Celecoxib Derivative AR-12 Has Broad-Spectrum Antifungal Activity In Vitro and Improves the Activity of Fluconazole in a Murine Model of Cryptococcosis. Antimicrobial agents and chemotherapy, 60 12, 7115-7127

2015

Calderon, Enrique J; Cushion, Melanie T; Xiao, Lihua; Lorenzo-Morales, Jacob; Matos, Olga; Kaneshiro, Edna S; Weiss, Louis M 2015. The 13th International Workshops on Opportunistic Protists (IWOP13). The Journal of eukaryotic microbiology, 62 5, 701-9

Mor, Visesato; Rella, Antonella; Farnoud, Amir M; Singh, Ashutosh; Munshi, Mansa; Bryan, Arielle; Naseem, Shamoon; Konopka, James B; Ojima, Iwao; Bullesbach, Erika; Ashbaugh, Alan; Linke, Michael J; Cushion, Melanie; Collins, Margaret; Ananthula, Hari Krishna; Sallans, Larry; Desai, Pankaj B; Wiederhold, Nathan P; Fothergill, Annette W; Kirkpatrick, William R; Patterson, Thomas; Wong, Lai Hong; Sinha, Sunita; Giaever, Guri; Nislow, Corey; Flaherty, Patrick; Pan, Xuewen; Cesar, Gabriele Vargas; de Melo Tavares, Patricia; Frases, Susana; Miranda, Kildare; Rodrigues, Marcio L; Luberto, Chiara; Nimrichter, Leonardo; Del Poeta, Maurizio 2015. Identification of a New Class of Antifungals Targeting the Synthesis of Fungal Sphingolipids. mBio, 6 3, e00647