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Photo of  Ralph E. Vatner, MD,PhD

Ralph E. Vatner, MD,PhD

Adjunct Assistant Professor

Radiation Oncology | College of Medicine

Education/Credentials
  • Fellowship: Harvard Medical School, Francis H. Burr Proton Center (Pediatric Proton Therapy )
  • Residency: New York University School of Medicine (Radiation Oncology)
  • Intern: Mount Sinai Medical Center (Internal Medicine)
  • Ph.D.: University of Connecticut School of Medicine (Biomedical Science, Immunology)
  • Medical Degree: University of Connecticut School of Medicine (Medicine)
  • Bachelor of Arts: Haverford College (Chemistry)
Board Certifications & Licenses

American Board of Radiology (Radiation Oncology) (Certification Date: 2016-05-17)

Specialties

Radiation Oncology

Contact Information

Clinical Interests

Leukemia

Radiation Oncology

Acute Lymphocytic Leukemia

Acute Myeloid Leukemia

Adenocarcinoma

Adenosquamous Carcinoma

Bone Marrow Cancers

Brain Cancers

Brain Metastases

Brain Stem Tumor

Brain Tumor

Cancer

Central Nervous System Tumors

Cerebellar Cancers

Cerebral Arterial Disease

Cerebral Contusion

Cerebral Hemorrhage

Cerebral Palsy

Cerebral Small Vessel Disease

Cerebral Ventricle Tumor

Chondrosarcoma

Chordoma

Ependymoblastoma

Ewing Sarcoma

Ganglioneuroblastoma

Glioma

Glioneuronal Tumor

Gliosarcoma

Infratentorial Cancers

Leptomeningeal Disease

Malignant Peripheral Nerve Sheath Tumor

Medulloblastoma

Metastasis Cancers

Neoplasm

Nerve Sheath Tumors

Nerve Tumors

Neurilemmoma

Neuroblastoma

Neurocytoma

Neurofibrosarcoma

Olfactory Neuroblastoma (Esthesioneuroblastoma)

Osteogenic Sarcoma (Osteosarcoma)

Pineoblastoma

Plexiform Neurofibroma

Precursor B-Cell Lymphoblastic Leukemia-Lymphoma

Precursor Cell Lymphoblastic Leukemia-Lymphoma

Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

Primary Central Nervous System (CNS) Lymphoma

Primitive Neuroectodermal Tumors

Retinoblastoma

Rhabdomyosarcoma

Skull-Base Tumors

Spinal Cord Cancer

Spinal Tumors

Squamous Cell Carcinoma

Subependymal Glioma

T-cell lymphoma

T-Cell, Cutaneous Lymphoma

T-Cell, Peripheral Lymphoma

Peer Reviewed Publications

Shukla, Samriddhi; Saha, Taniya; Rama, Nihar; Acharya, Anusha; Le, Tien; Bian, Fenghua; Donovan, Johnny; Tan, Lin Abigail; Vatner, Ralph; Kalinichenko, Vladimir; Mascia, Anthony; Perentesis, John P; Kalin, Tanya V 2023. Ultra-high dose-rate proton FLASH improves tumor control. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 186 , 109741

Howell, Jackson; Dandoy, Christopher; Wright, Jordan M; Chow, Lionel; El-Sheikh, Ayman; Dole, Mukund; Vatner, Ralph E; Kamian, Kambiz 2022. Extraneural recurrence of an intracranial nongerminomatous germ cell tumor to cervical lymph nodes in a pediatric patient: Case report. Cancer reports (Hoboken, N.J.), 5 8, e1586

Howell, Jackson; Dandoy, Christopher; Wright, Jordan M; Chow, Lionel; El-Sheikh, Ayman; Dole, Mukund; Vatner, Ralph E; Kamian, Kambiz 2022. Extraneural recurrence of an intracranial nongerminomatous germ cell tumor to cervical lymph nodes in a pediatric patient: Case report. Cancer reports (Hoboken, N.J.), 5 8, e1586

Williams, Michael T; Sugimoto, Chiho; Regan, Samantha L; Pitzer, Emily M; Fritz, Adam L; Sertorio, Mathieu; Mascia, Anthony E; Vatner, Ralph E; Perentesis, John P; Vorhees, Charles V 2022. Cognitive and behavioral effects of whole brain conventional or high dose rate (FLASH) proton irradiation in a neonatal Sprague Dawley rat model. PloS one, 17 9, e0274007

Williams, Michael T; Sugimoto, Chiho; Regan, Samantha L; Pitzer, Emily M; Fritz, Adam L; Sertorio, Mathieu; Mascia, Anthony E; Vatner, Ralph E; Perentesis, John P; Vorhees, Charles V 2022. Cognitive and behavioral effects of whole brain conventional or high dose rate (FLASH) proton irradiation in a neonatal Sprague Dawley rat model. PloS one, 17 9, e0274007

Eaton, Bree R; Claude, Line; Indelicato, Daniel J; Vatner, Ralph; Yeh, Brian; Schwarz, Rudolf; Laack, Nadia 2021. Ewing sarcoma. Pediatric blood & cancer, 68 Suppl 2 , e28355

Eaton, Bree R; Claude, Line; Indelicato, Daniel J; Vatner, Ralph; Yeh, Brian; Schwarz, Rudolf; Laack, Nadia 2021. Ewing sarcoma. Pediatric blood & cancer, 68 Suppl 2 , e28355

Vorhees, C V; Vatner, R E; Williams, M T 2021. Review of Conventional and High Dose Rate Brain Radiation (FLASH): Neurobehavioural, Neurocognitive and Assessment Issues in Rodent Models. Clinical oncology (Royal College of Radiologists (Great Britain)), 33 11, e482-e491

Vorhees, C V; Vatner, R E; Williams, M T 2021. Review of Conventional and High Dose Rate Brain Radiation (FLASH): Neurobehavioural, Neurocognitive and Assessment Issues in Rodent Models. Clinical oncology (Royal College of Radiologists (Great Britain)), 33 11, e482-e491

Eaton, Bree R; Schwarz, Rudolf; Vatner, Ralph; Yeh, Brian; Claude, Line; Indelicato, Daniel J; Laack, Nadia 2020. Osteosarcoma. Pediatric blood & cancer, , e28352

Lawell, Miranda P; Indelicato, Daniel J; Paulino, Arnold C; Hartsell, William; Laack, Nadia N; Ermoian, Ralph P; Perentesis, John P; Vatner, Ralph; Perkins, Stephanie; Mangona, Victor S; Hill-Kayser, Christine E; Wolden, Suzanne L; Kwok, Young; Chang, John Han-Chih; Wilkinson, J Ben; MacEwan, Iain; Chang, Andrew L; Eaton, Bree R; Ladra, Matthew M; Gallotto, Sara L; Weyman, Elizabeth A; Bajaj, Benjamin V M; Baliga, Sujith; Yeap, Beow Y; Berrington de Gonzalez, Amy; Yock, Torunn I 2020. An open invitation to join the Pediatric Proton/Photon Consortium Registry to standardize data collection in pediatric radiation oncology. The British journal of radiology, 93 1107, 20190673

Sabulski, Anthony; Bartlett, Allison L; Koch, Bernadette L; Vatner, Ralph; Mizukawa, Benjamin; Phillips, Christine L 2020. Hyperdiploid Precursor B-acute Lymphoblastic Leukemia Presenting as a Cavernous Sinus Mass in a 4-Year-old Male. Journal of pediatric hematology/oncology, ,

Vatner, Ralph; James, Charles D; Sathiaseelan, Vythialingam; Bondra, Kathryn M; Kalapurakal, John A; Houghton, Peter J 2020. Radiation therapy and molecular-targeted agents in preclinical testing for immunotherapy, brain tumors, and sarcomas: Opportunities and challenges. Pediatric blood & cancer, , e28439

Williams, Michael T; Sugimoto, Chiho; Regan, Samantha L; Pitzer, Emily M; Fritz, Adam L; Mascia, Anthony E; Sertorio, Mathieu; Vatner, Ralph E; Perentesis, John P; Vorhees, Charles V 2020. Whole brain proton irradiation in adult Sprague Dawley rats produces dose dependent and non-dependent cognitive, behavioral, and dopaminergic effects. Scientific reports, 10 1, 21584

Williams, Michael T; Sugimoto, Chiho; Regan, Samantha L; Pitzer, Emily M; Fritz, Adam L; Mascia, Anthony E; Sertorio, Mathieu; Vatner, Ralph E; Perentesis, John P; Vorhees, Charles V 2020. Whole brain proton irradiation in adult Sprague Dawley rats produces dose dependent and non-dependent cognitive, behavioral, and dopaminergic effects. Scientific reports, 10 1, 21584

Medek, Sara; De, Brian; Pater, Luke; Breneman, John; Mahajan, Anita; Wolden, Suzanne; Vatner, Ralph E 2019. Practice patterns among radiation oncologists treating pediatric patients with proton craniospinal irradiation. Practical radiation oncology, ,

Turpin, Brian; Pressey, Joseph G; Nagarajan, Rajaram; Weiss, Brian D; Trout, Andrew T; Gelfand, Michael J; Pater, Luke; Vatner, Ralph E; Breneman, John C; Dasgupta, Roshni 2019. Sentinel lymph node biopsy in head and neck rhabdomyosarcoma. Pediatric blood & cancer, 66 3, e27532

Vatner, Ralph E; Janssen, Edith M 2019. STING, DCs and the link between innate and adaptive tumor immunity. Molecular immunology, 110 , 13-23

4. Sertorio M, Perentesis JP, Vatner RE, Mascia AE, Zheng Y, Wells SI. 2018. Cancer cell metabolism: implications for X-ray and particle radiation therapy. Cancer cell metabolism: implications for X-ray and particle radiation therapy. International Journal of Particle Therapy, 5 1,

Sertorio, Mathieu; Perentesis, John P; Vatner, Ralph E; Mascia, Anthony E; Zheng, Yi; Wells, Susanne I 2018. Cancer Cell Metabolism: Implications for X-ray and Particle Radiation Therapy. International journal of particle therapy, 5 1, 40-48

Vatner, Ralph E; Niemierko, Andrzej; Misra, Madhusmita; Weyman, Elizabeth A; Goebel, Claire P; Ebb, David H; Jones, Robin M; Huang, Mary S; Mahajan, Anita; Grosshans, David R; Paulino, Arnold C; Stanley, Takara; MacDonald, Shannon M; Tarbell, Nancy J; Yock, Torunn I 2018. Endocrine Deficiency As a Function of Radiation Dose to the Hypothalamus and Pituitary in Pediatric and Young Adult Patients With Brain Tumors. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 36 28, 2854-2862

Shin SM, Vatner RE, Tam M, Golfinos JG, Narayana A, Kondziolka D, Silverman JS 2015. Resection Followed by Involved-Field Fractionated Radiotherapy in the Management of Single Brain Metastasis. Front Oncol. , 5 206,

Vatner RE and Formenti SC 2015. Myeloid Derived Cells in Tumors: Effects of Radiation Semin Radiat Oncol, 25 1, 18

Vatner RE, Cooper BT, Vanpouille-Box C, Demaria S, Formenti SC. 2014. Combinations of Immunotherapy and Radiation in Cancer Therapy. Front Oncol. , 4 325,

Vatner RE, Srivastava PK 2010. The tailless complex polypeptide-1 ring complex of the heat shock protein 60 family facilitates cross-priming of CD8 responses specific for chaperoned peptides J Immunol, 185 11, 6765