Contact Information Hoxworth Center (4-5) 5072 Office 513-558-1450 Email wang4xf@ucmail.uc.edu Peer Reviewed Publications J. Austin, Y. Tu, K. Pal and X. Wang 2023. Vinculin transmits high-level integrin tensions which are dispensable for focal adhesion formation Biophysical Journal, , K. Pal, Y. Tu and X. Wang 2022. Single-molecule force imaging reveals that podosome formation requires no extracellular integrin-ligand tensions or interactions ACS Nano, , Y. Tu, K. Pal, J. Austin and X. Wang 2022. Filopodial adhesive force in discrete nodes revealed by integrin molecular tension imaging Current Biology, , K. Pal, Y. Zhao, Y. Wang and X. Wang 2021. Ubiquitous membrane-bound DNase activity in podosomes and invadopodia Journal of Cell Biology, , S. Mao, A. Sarkar, Y. Wang, C. Song, D. N. LeVine, X. Wang and L. Que 2021. Microfluidic chip grafted with integrin tension sensors for evaluating the effects of flowing shear stress and ROCK inhibitor on platelets Lab on a chip, , Y. Tu and X. Wang 2021. Tracking cell migration by cellular force footprint recorded with a mechano-optical biosensor Biosensors and Bioelectronics, , A. Sarkar, D. N. LeVine, N. Kuzmina, Y. Zhao and X. Wang 2020. Cell migration driven by self-generated integrin ligand gradient on ligand-labile surfaces Current Biology, , Y. Tu and X. Wang 2020. Recent Advances in Cell Adhesive Force Microscopy Sensors, , Y. Zhao, A. Sarkar and X. Wang 2020. Peptide nucleic acid based tension sensor for cellular force imaging with strong DNase resistance Biosensors and Bioelectronics, , Y. Zhao, K. Pal, Y. Tu and X. Wang 2020. Cellular force nanoscopy with 50 nm resolution based on integrin molecular tension imaging and localization Journal of the American Chemical Society, , 12. Y. Wang, Y. Zhao, A. Sarkar, X. Wang 2019. Optical sensor revealed abnormal nuclease spatial activity on cancer cell membrane Journal of Biophotonics, , Y. Zhao, N. Wetter and X. Wang 2019. Imaging integrin tension and cellular force at submicron resolution with integrative tension sensor Journal of Visualized Experiments, , A. Sarkar, Y. Zhao, Y. Wang and X. Wang 2018. Force-activatable coating enables high-resolution cellular force imaging directly on regular cell culture surfaces Physical Biology, , X. Wang, S. Park, L. Zeng, A. Jain and T. Ha 2018. Towards single-cell single-molecule pull-down Biophysical Journal, , Y. Wang, D. N. LeVine, M. Gannon, Y. Zhao, A. Sarkar, B. Hoch and X. Wang 2018. Force-activatable biosensor enables single platelet force mapping directly by fluorescence imaging Biosensors and Bioelectronics, , Y. Zhao, Y. Wang, A. Sarkar and X. Wang 2018. Keratocytes Generate High Integrin Tension at the Trailing Edge to Mediate Rear De-adhesion during Rapid Cell Migration iScience, , Y. Wang and X. Wang 2016. Integrins outside focal adhesions transmit tensions during stable cell adhesion Scientific Reports, , X. Wang and T. Ha 2013. Defining Single Molecular Forces Required to Activate Integrin and Notch Signaling Science, ,
Peer Reviewed Publications J. Austin, Y. Tu, K. Pal and X. Wang 2023. Vinculin transmits high-level integrin tensions which are dispensable for focal adhesion formation Biophysical Journal, , K. Pal, Y. Tu and X. Wang 2022. Single-molecule force imaging reveals that podosome formation requires no extracellular integrin-ligand tensions or interactions ACS Nano, , Y. Tu, K. Pal, J. Austin and X. Wang 2022. Filopodial adhesive force in discrete nodes revealed by integrin molecular tension imaging Current Biology, , K. Pal, Y. Zhao, Y. Wang and X. Wang 2021. Ubiquitous membrane-bound DNase activity in podosomes and invadopodia Journal of Cell Biology, , S. Mao, A. Sarkar, Y. Wang, C. Song, D. N. LeVine, X. Wang and L. Que 2021. Microfluidic chip grafted with integrin tension sensors for evaluating the effects of flowing shear stress and ROCK inhibitor on platelets Lab on a chip, , Y. Tu and X. Wang 2021. Tracking cell migration by cellular force footprint recorded with a mechano-optical biosensor Biosensors and Bioelectronics, , A. Sarkar, D. N. LeVine, N. Kuzmina, Y. Zhao and X. Wang 2020. Cell migration driven by self-generated integrin ligand gradient on ligand-labile surfaces Current Biology, , Y. Tu and X. Wang 2020. Recent Advances in Cell Adhesive Force Microscopy Sensors, , Y. Zhao, A. Sarkar and X. Wang 2020. Peptide nucleic acid based tension sensor for cellular force imaging with strong DNase resistance Biosensors and Bioelectronics, , Y. Zhao, K. Pal, Y. Tu and X. Wang 2020. Cellular force nanoscopy with 50 nm resolution based on integrin molecular tension imaging and localization Journal of the American Chemical Society, , 12. Y. Wang, Y. Zhao, A. Sarkar, X. Wang 2019. Optical sensor revealed abnormal nuclease spatial activity on cancer cell membrane Journal of Biophotonics, , Y. Zhao, N. Wetter and X. Wang 2019. Imaging integrin tension and cellular force at submicron resolution with integrative tension sensor Journal of Visualized Experiments, , A. Sarkar, Y. Zhao, Y. Wang and X. Wang 2018. Force-activatable coating enables high-resolution cellular force imaging directly on regular cell culture surfaces Physical Biology, , X. Wang, S. Park, L. Zeng, A. Jain and T. Ha 2018. Towards single-cell single-molecule pull-down Biophysical Journal, , Y. Wang, D. N. LeVine, M. Gannon, Y. Zhao, A. Sarkar, B. Hoch and X. Wang 2018. Force-activatable biosensor enables single platelet force mapping directly by fluorescence imaging Biosensors and Bioelectronics, , Y. Zhao, Y. Wang, A. Sarkar and X. Wang 2018. Keratocytes Generate High Integrin Tension at the Trailing Edge to Mediate Rear De-adhesion during Rapid Cell Migration iScience, , Y. Wang and X. Wang 2016. Integrins outside focal adhesions transmit tensions during stable cell adhesion Scientific Reports, , X. Wang and T. Ha 2013. Defining Single Molecular Forces Required to Activate Integrin and Notch Signaling Science, ,
J. Austin, Y. Tu, K. Pal and X. Wang 2023. Vinculin transmits high-level integrin tensions which are dispensable for focal adhesion formation Biophysical Journal, , K. Pal, Y. Tu and X. Wang 2022. Single-molecule force imaging reveals that podosome formation requires no extracellular integrin-ligand tensions or interactions ACS Nano, , Y. Tu, K. Pal, J. Austin and X. Wang 2022. Filopodial adhesive force in discrete nodes revealed by integrin molecular tension imaging Current Biology, , K. Pal, Y. Zhao, Y. Wang and X. Wang 2021. Ubiquitous membrane-bound DNase activity in podosomes and invadopodia Journal of Cell Biology, , S. Mao, A. Sarkar, Y. Wang, C. Song, D. N. LeVine, X. Wang and L. Que 2021. Microfluidic chip grafted with integrin tension sensors for evaluating the effects of flowing shear stress and ROCK inhibitor on platelets Lab on a chip, , Y. Tu and X. Wang 2021. Tracking cell migration by cellular force footprint recorded with a mechano-optical biosensor Biosensors and Bioelectronics, , A. Sarkar, D. N. LeVine, N. Kuzmina, Y. Zhao and X. Wang 2020. Cell migration driven by self-generated integrin ligand gradient on ligand-labile surfaces Current Biology, , Y. Tu and X. Wang 2020. Recent Advances in Cell Adhesive Force Microscopy Sensors, , Y. Zhao, A. Sarkar and X. Wang 2020. Peptide nucleic acid based tension sensor for cellular force imaging with strong DNase resistance Biosensors and Bioelectronics, , Y. Zhao, K. Pal, Y. Tu and X. Wang 2020. Cellular force nanoscopy with 50 nm resolution based on integrin molecular tension imaging and localization Journal of the American Chemical Society, , 12. Y. Wang, Y. Zhao, A. Sarkar, X. Wang 2019. Optical sensor revealed abnormal nuclease spatial activity on cancer cell membrane Journal of Biophotonics, , Y. Zhao, N. Wetter and X. Wang 2019. Imaging integrin tension and cellular force at submicron resolution with integrative tension sensor Journal of Visualized Experiments, , A. Sarkar, Y. Zhao, Y. Wang and X. Wang 2018. Force-activatable coating enables high-resolution cellular force imaging directly on regular cell culture surfaces Physical Biology, , X. Wang, S. Park, L. Zeng, A. Jain and T. Ha 2018. Towards single-cell single-molecule pull-down Biophysical Journal, , Y. Wang, D. N. LeVine, M. Gannon, Y. Zhao, A. Sarkar, B. Hoch and X. Wang 2018. Force-activatable biosensor enables single platelet force mapping directly by fluorescence imaging Biosensors and Bioelectronics, , Y. Zhao, Y. Wang, A. Sarkar and X. Wang 2018. Keratocytes Generate High Integrin Tension at the Trailing Edge to Mediate Rear De-adhesion during Rapid Cell Migration iScience, , Y. Wang and X. Wang 2016. Integrins outside focal adhesions transmit tensions during stable cell adhesion Scientific Reports, , X. Wang and T. Ha 2013. Defining Single Molecular Forces Required to Activate Integrin and Notch Signaling Science, ,