Education/CredentialsPh.D.: University of Cincinnati ((ABD)): University of Cincinnati (Molecular Genetics): Ohio University (Experimental Psychology/Zoological and Biomedical Sciences)BA: Ohio University (Psychology, Summa Cum Laude in 3 years) Contact Information Medical Sciences Building 6353 Office 513-558-4831 Email koprasej@ucmail.uc.edu Research InterestsI manage programs across a spectrum of needs including scientific promotion, research program design and implementation, strategic planning, and financial tracking. I have a variety of scientific interests, which is why I decided to pursue a PhD in epidemiology. I have studied a number of disorders including smooth muscle cell proliferation in heart disease, DNA repair in ataxia telangiectasia, second messenger signalling in pancreatic cancer, and protein folding in hereditary pancrea... Peer Reviewed Publications Astrinidis, Aristotelis; Li, Chenggang; Zhang, Erik Y; Zhao, Xueheng; Zhao, Shuyang; Guo, Minzhe; Olatoke, Tasnim; Mattam, Ushodaya; Huang, Rong; Zhang, Alan G; Pitstick, Lori; Kopras, Elizabeth J; Gupta, Nishant; Jandarov, Roman; Smith, Eric P; Fugate, Elizabeth; Lindquist, Diana; Markiewski, Maciej M; Karbowniczek, Magdalena; Wikenheiser-Brokamp, Kathryn A; Setchell, Kenneth D R; McCormack, Francis X; Xu, Yan; Yu, Jane J 2023. Upregulation of acid ceramidase contributes to tumor progression in tuberous sclerosis complex. JCI insight, 8 9, Du, Yina; Guo, Minzhe; Wu, Yixin; Wagner, Andrew; Perl, Anne Karina; Wikenheiser-Brokamp, Kathryn; Yu, Jane; Gupta, Nishant; Kopras, Elizabeth; Krymskaya, Vera; Obraztsova, Kseniya; Tang, Yan; Kwiatkowski, David; Henske, Elizabeth P; McCormack, Francis; Xu, Yan 2023. Lymphangioleiomyomatosis (LAM) Cell Atlas. Thorax, 78 1, 85-87Gupta, Nishant; Zhang, Bin; Zhou, Yuan; McCormack, Francis X; Ingledue, Rebecca; Robbins, Nathan; Kopras, Elizabeth J; McMahan, Susan; Singla, Abhishek; Swigris, Jeffrey; Cole, Adam G; Holz, Marina K 2023. Safety and efficacy of combined resveratrol and sirolimus in lymphangioleiomyomatosis. Chest, , Olatoke, Tasnim; Wagner, Andrew; Astrinidis, Aristotelis; Zhang, Erik Y; Guo, Minzhe; Zhang, Alan G; Mattam, Ushodaya; Kopras, Elizabeth J; Gupta, Nishant; Smith, Eric P; Karbowniczek, Magdalena; Markiewski, Maciej M; Wikenheiser-Brokamp, Kathryn A; Whitsett, Jeffrey A; McCormack, Francis X; Xu, Yan; Yu, Jane J 2023. Single-cell multiomic analysis identifies a HOX-PBX gene network regulating the survival of lymphangioleiomyomatosis cells. Science advances, 9 19, eadf8549Uehara, Yasuaki; Tanaka, Yusuke; Zhao, Shuyang; Nikolaidis, Nikolaos M; Pitstick, Lori B; Wu, Huixing; Yu, Jane J; Zhang, Erik; Hasegawa, Yoshihiro; Noel, John G; Gardner, Jason C; Kopras, Elizabeth J; Haffey, Wendy D; Greis, Kenneth D; Guo, Jinbang; Woods, Jason C; Wikenheiser-Brokamp, Kathryn A; Kyle, Jennifer E; Ansong, Charles; Teitelbaum, Steven L; Inoue, Yoshikazu; Altinişik, Göksel; Xu, Yan; McCormack, Francis X 2023. Insights into pulmonary phosphate homeostasis and osteoclastogenesis emerge from the study of pulmonary alveolar microlithiasis. Nature communications, 14 1, 1205Cortinas, Noella; Liu, Jie; Kopras, Elizabeth; Memon, Humna; Burkes, Robert; Gupta, Nishant 2022. Impact of Age, Menopause, and Sirolimus on Spontaneous Pneumothoraces in Lymphangioleiomyomatosis. Chest, , Hudock, K M; Collins, M S; Imbrogno, M A; Kramer, E L; Brewington, J J; Ziady, A; Zhang, N; Snowball, J; Xu, Y; Carey, B C; Horio, Y; O'Grady, S M; Kopras, E J; Meeker, J; Morgan, H; Ostmann, A J; Skala, E; Siefert, M E; Na, C L; Davidson, C R; Gollomp, K; Mangalmurti, N; Trapnell, B C; Clancy, J P 2022. Alpha-1 antitrypsin limits neutrophil extracellular trap disruption of airway epithelial barrier function. Frontiers in immunology, 13 , 1023553Jose, Arun; Kopras, Elizabeth J; Shah, Shimul A; Elwing, Jean M 2022. Portopulmonary Hypertension Practice Patterns after Liver Transplantation. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, , Shaw, Brian M; Kopras, Elizabeth; Gupta, Nishant 2022. Menstrual Cycle-Related Respiratory Symptom Variability in Patients with Lymphangioleiomyomatosis. Annals of the American Thoracic Society, , Guo, Minzhe; Yu, Jane J; Perl, Anne Karina; Wikenheiser-Brokamp, Kathryn A; Riccetti, Matt; Zhang, Erik Y; Sudha, Parvathi; Adam, Mike; Potter, Andrew; Kopras, Elizabeth J; Giannikou, Krinio; Potter, S Steven; Sherman, Sue; Hammes, Stephen R; Kwiatkowski, David J; Whitsett, Jeffrey A; McCormack, Francis X; Xu, Yan 2020. Single Cell Transcriptomic Analysis Identifies a Unique Pulmonary Lymphangioleiomyomatosis Cell. American journal of respiratory and critical care medicine, , Hudock, Kristin M; Collins, Margaret S; Imbrogno, Michelle; Snowball, John; Kramer, Elizabeth L; Brewington, John J; Gollomp, Kandace; McCarthy, Cormac; Ostmann, Alicia J; Kopras, Elizabeth J; Davidson, Cynthia R; Srdiharan, Anusha; Arumugam, Paritha; Sengupta, Shaon; Xu, Yan; Worthen, G Scott; Trapnell, Bruce C; Clancy, John Paul 2020. Neutrophil extracellular traps activate IL-8 and IL-1 expression in human bronchial epithelia. American journal of physiology. Lung cellular and molecular physiology, , Lu, Yiyang; Liu, Xiaolei; Zhang, Erik; Kopras, Elizabeth J; Smith, Eric P; Astreinidis, Aristotelis; Li, Chenggang; Leung, Yuet-Kin; Ho, Shuk-Mei; Yu, Jane J 2020. Estrogen activates pyruvate kinase M2 and increases the growth of TSC2-deficient cells. PloS one, 15 2, e0228894Jönsson, Åsa Lina M; Bendstrup, Elisabeth; Mogensen, Susie; Kopras, Elizabeth J; McCormack, Francis X; Campo, Ilaria; Mariani, Francesca; Escribano-Montaner, Amparo; Holm, Are M; Del Mar Martinez-Colls, Maria; Pintos-Morell, Guillem; Taillé, Camille; Crestani, Bruno; Hilberg, Ole; Hvarregaard Christensen, Jane; Simonsen, Ulf 2019. Eight novel variants in the SLC34A2 gene in pulmonary alveolar microlithiasis. The European respiratory journal, , Singla, Abhishek; Kopras, Elizabeth J; Gupta, Nishant 2019. Spontaneous pneumothorax and air travel in Pulmonary Langerhans cell histiocytosis: A patient survey. Respiratory investigation, 57 6, 582-589Eckman, Mark H; Kopras, Elizabeth J; Montag-Leifling, Karen; Kirby, Lari P; Burns, Lisa; Indihar, Veronica M; Joseph, Patricia M 2017. Shared Decision-Making Tool for Self-Management of Home Therapies for Patients With Cystic Fibrosis. MDM policy & practice, 2 1, 2381468317715621Gupta, Nishant; Kopras, Elizabeth J; Henske, Elizabeth P; James, Laura E; El-Chemaly, Souheil; Veeraraghavan, Srihari; Drake, Matthew G; McCormack, Francis X 2017. Spontaneous Pneumothoraces in Patients with Birt-Hogg-Dubé Syndrome. Annals of the American Thoracic Society, 14 5, 706-713Li, Chenggang; Liu, Xiaolei; Liu, Yang; Zhang, Erik; Medepalli, Kantha; Masuda, Kohei; Li, Na; Kopras, Elizabeth J; Kwiatkowski, David J; Borchers, Michael T; Wikenheiser-Brokamp, Kathryn A; Osterburg, Andrew; Mays, Maxwell; Sun, Yang; Plas, David R; Sun, Julia L; Franz, David N; Capal, Jamie K; Alayev, Anya; Holz, Marina K; Krueger, Darcy A; Siroky, Brian J; Yu, Jane J 2017. Tuberin Regulates Prostaglandin Receptor-mediated Viability, via Rheb, in mTORC1-hyperactive Cells. Molecular cancer research : MCR, , Lu, Calvin; Lee, Hye-Seung; Pappas, George P; Dilling, Daniel F; Burger, Charles D; Shifren, Adrian; Veeraraghavan, Srihari; Chapman, Jeffrey T; Parambil, Joseph; Ruoss, Stephen J; Young, Lisa R; Hammes, Stephen R; Kopras, Elizabeth J; Roads, Tammy; Krischer, Jeffrey P; McCormack, Francis X 2017. A Phase II Clinical Trial of an Aromatase Inhibitor for Postmenopausal Women with Lymphangioleiomyomatosis. Annals of the American Thoracic Society, 14 6, 919-928Oster, Robert A; Lindsell, Christopher J; Welty, Leah J; Mazumdar, Madhu; Thurston, Sally W; Rahbar, Mohammad H; Carter, Rickey E; Pollock, Bradley H; Cucchiara, Andrew J; Kopras, Elizabeth J; Jovanovic, Borko D; Enders, Felicity T 2015. Assessing statistical competencies in clinical and translational science education: one size does not fit all. Clinical and translational science, 8 1, 32-42Kopras, Elizabeth; Potluri, Veena; Bermudez, Mei-Ling; Williams, Karin; Belcher, Scott; Kasper, Susan 2014. Actions of endocrine-disrupting chemicals on stem/progenitor cells during development and disease. Endocrine-related cancer, 21 2, T1-12Haynes, Erin N; Beidler, Caroline; Wittberg, Richard; Meloncon, Lisa; Parin, Megan; Kopras, Elizabeth J; Succop, Paul; Dietrich, Kim N 2011. Developing a bidirectional academic-community partnership with an Appalachian-American community for environmental health research and risk communication. Environmental health perspectives, 119 10, 1364-72Dwivedi, Alok Kumar; Dwivedi, Sada Nand; Deo, Suryanarayana; Shukla, Rakesh; Kopras, Elizabeth 2010. Statistical models for predicting number of involved nodes in breast cancer patients. Health, 2 7, 641-651Dixon, Kathleen; Kopras, Elizabeth 2004. Genetic alterations and DNA repair in human carcinogenesis. Seminars in cancer biology, 14 6, 441-8Ulrich, C D; Kopras, E; Wu, Y; Ward, S 2000. Hereditary pancreatitis: epidemiology, molecules, mutations, and models. The Journal of laboratory and clinical medicine, 136 4, 260-74Ulrich, C D; Wood, P; Hadac, E M; Kopras, E; Whitcomb, D C; Miller, L J 1998. Cellular distribution of secretin receptor expression in rat pancreas. The American journal of physiology, 275 6 Pt 1, G1437-44Jiang, S; Kopras, E; McMichael, M; Bell, R H; Ulrich, C D 1997. Vasoactive intestinal peptide (VIP) stimulates in vitro growth of VIP-1 receptor-bearing human pancreatic adenocarcinoma-derived cells. Cancer research, 57 8, 1475-80Katoh, Y; Loukianov, E; Kopras, E; Zilberman, A; Periasamy, M 1994. Identification of functional promoter elements in the rabbit smooth muscle myosin heavy chain gene. The Journal of biological chemistry, 269 48, 30538-45
Research InterestsI manage programs across a spectrum of needs including scientific promotion, research program design and implementation, strategic planning, and financial tracking. I have a variety of scientific interests, which is why I decided to pursue a PhD in epidemiology. I have studied a number of disorders including smooth muscle cell proliferation in heart disease, DNA repair in ataxia telangiectasia, second messenger signalling in pancreatic cancer, and protein folding in hereditary pancrea...
Peer Reviewed Publications Astrinidis, Aristotelis; Li, Chenggang; Zhang, Erik Y; Zhao, Xueheng; Zhao, Shuyang; Guo, Minzhe; Olatoke, Tasnim; Mattam, Ushodaya; Huang, Rong; Zhang, Alan G; Pitstick, Lori; Kopras, Elizabeth J; Gupta, Nishant; Jandarov, Roman; Smith, Eric P; Fugate, Elizabeth; Lindquist, Diana; Markiewski, Maciej M; Karbowniczek, Magdalena; Wikenheiser-Brokamp, Kathryn A; Setchell, Kenneth D R; McCormack, Francis X; Xu, Yan; Yu, Jane J 2023. Upregulation of acid ceramidase contributes to tumor progression in tuberous sclerosis complex. JCI insight, 8 9, Du, Yina; Guo, Minzhe; Wu, Yixin; Wagner, Andrew; Perl, Anne Karina; Wikenheiser-Brokamp, Kathryn; Yu, Jane; Gupta, Nishant; Kopras, Elizabeth; Krymskaya, Vera; Obraztsova, Kseniya; Tang, Yan; Kwiatkowski, David; Henske, Elizabeth P; McCormack, Francis; Xu, Yan 2023. Lymphangioleiomyomatosis (LAM) Cell Atlas. Thorax, 78 1, 85-87Gupta, Nishant; Zhang, Bin; Zhou, Yuan; McCormack, Francis X; Ingledue, Rebecca; Robbins, Nathan; Kopras, Elizabeth J; McMahan, Susan; Singla, Abhishek; Swigris, Jeffrey; Cole, Adam G; Holz, Marina K 2023. Safety and efficacy of combined resveratrol and sirolimus in lymphangioleiomyomatosis. Chest, , Olatoke, Tasnim; Wagner, Andrew; Astrinidis, Aristotelis; Zhang, Erik Y; Guo, Minzhe; Zhang, Alan G; Mattam, Ushodaya; Kopras, Elizabeth J; Gupta, Nishant; Smith, Eric P; Karbowniczek, Magdalena; Markiewski, Maciej M; Wikenheiser-Brokamp, Kathryn A; Whitsett, Jeffrey A; McCormack, Francis X; Xu, Yan; Yu, Jane J 2023. Single-cell multiomic analysis identifies a HOX-PBX gene network regulating the survival of lymphangioleiomyomatosis cells. Science advances, 9 19, eadf8549Uehara, Yasuaki; Tanaka, Yusuke; Zhao, Shuyang; Nikolaidis, Nikolaos M; Pitstick, Lori B; Wu, Huixing; Yu, Jane J; Zhang, Erik; Hasegawa, Yoshihiro; Noel, John G; Gardner, Jason C; Kopras, Elizabeth J; Haffey, Wendy D; Greis, Kenneth D; Guo, Jinbang; Woods, Jason C; Wikenheiser-Brokamp, Kathryn A; Kyle, Jennifer E; Ansong, Charles; Teitelbaum, Steven L; Inoue, Yoshikazu; Altinişik, Göksel; Xu, Yan; McCormack, Francis X 2023. Insights into pulmonary phosphate homeostasis and osteoclastogenesis emerge from the study of pulmonary alveolar microlithiasis. Nature communications, 14 1, 1205Cortinas, Noella; Liu, Jie; Kopras, Elizabeth; Memon, Humna; Burkes, Robert; Gupta, Nishant 2022. Impact of Age, Menopause, and Sirolimus on Spontaneous Pneumothoraces in Lymphangioleiomyomatosis. Chest, , Hudock, K M; Collins, M S; Imbrogno, M A; Kramer, E L; Brewington, J J; Ziady, A; Zhang, N; Snowball, J; Xu, Y; Carey, B C; Horio, Y; O'Grady, S M; Kopras, E J; Meeker, J; Morgan, H; Ostmann, A J; Skala, E; Siefert, M E; Na, C L; Davidson, C R; Gollomp, K; Mangalmurti, N; Trapnell, B C; Clancy, J P 2022. Alpha-1 antitrypsin limits neutrophil extracellular trap disruption of airway epithelial barrier function. Frontiers in immunology, 13 , 1023553Jose, Arun; Kopras, Elizabeth J; Shah, Shimul A; Elwing, Jean M 2022. Portopulmonary Hypertension Practice Patterns after Liver Transplantation. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, , Shaw, Brian M; Kopras, Elizabeth; Gupta, Nishant 2022. Menstrual Cycle-Related Respiratory Symptom Variability in Patients with Lymphangioleiomyomatosis. Annals of the American Thoracic Society, , Guo, Minzhe; Yu, Jane J; Perl, Anne Karina; Wikenheiser-Brokamp, Kathryn A; Riccetti, Matt; Zhang, Erik Y; Sudha, Parvathi; Adam, Mike; Potter, Andrew; Kopras, Elizabeth J; Giannikou, Krinio; Potter, S Steven; Sherman, Sue; Hammes, Stephen R; Kwiatkowski, David J; Whitsett, Jeffrey A; McCormack, Francis X; Xu, Yan 2020. Single Cell Transcriptomic Analysis Identifies a Unique Pulmonary Lymphangioleiomyomatosis Cell. American journal of respiratory and critical care medicine, , Hudock, Kristin M; Collins, Margaret S; Imbrogno, Michelle; Snowball, John; Kramer, Elizabeth L; Brewington, John J; Gollomp, Kandace; McCarthy, Cormac; Ostmann, Alicia J; Kopras, Elizabeth J; Davidson, Cynthia R; Srdiharan, Anusha; Arumugam, Paritha; Sengupta, Shaon; Xu, Yan; Worthen, G Scott; Trapnell, Bruce C; Clancy, John Paul 2020. Neutrophil extracellular traps activate IL-8 and IL-1 expression in human bronchial epithelia. American journal of physiology. Lung cellular and molecular physiology, , Lu, Yiyang; Liu, Xiaolei; Zhang, Erik; Kopras, Elizabeth J; Smith, Eric P; Astreinidis, Aristotelis; Li, Chenggang; Leung, Yuet-Kin; Ho, Shuk-Mei; Yu, Jane J 2020. Estrogen activates pyruvate kinase M2 and increases the growth of TSC2-deficient cells. PloS one, 15 2, e0228894Jönsson, Åsa Lina M; Bendstrup, Elisabeth; Mogensen, Susie; Kopras, Elizabeth J; McCormack, Francis X; Campo, Ilaria; Mariani, Francesca; Escribano-Montaner, Amparo; Holm, Are M; Del Mar Martinez-Colls, Maria; Pintos-Morell, Guillem; Taillé, Camille; Crestani, Bruno; Hilberg, Ole; Hvarregaard Christensen, Jane; Simonsen, Ulf 2019. Eight novel variants in the SLC34A2 gene in pulmonary alveolar microlithiasis. The European respiratory journal, , Singla, Abhishek; Kopras, Elizabeth J; Gupta, Nishant 2019. Spontaneous pneumothorax and air travel in Pulmonary Langerhans cell histiocytosis: A patient survey. Respiratory investigation, 57 6, 582-589Eckman, Mark H; Kopras, Elizabeth J; Montag-Leifling, Karen; Kirby, Lari P; Burns, Lisa; Indihar, Veronica M; Joseph, Patricia M 2017. Shared Decision-Making Tool for Self-Management of Home Therapies for Patients With Cystic Fibrosis. MDM policy & practice, 2 1, 2381468317715621Gupta, Nishant; Kopras, Elizabeth J; Henske, Elizabeth P; James, Laura E; El-Chemaly, Souheil; Veeraraghavan, Srihari; Drake, Matthew G; McCormack, Francis X 2017. Spontaneous Pneumothoraces in Patients with Birt-Hogg-Dubé Syndrome. Annals of the American Thoracic Society, 14 5, 706-713Li, Chenggang; Liu, Xiaolei; Liu, Yang; Zhang, Erik; Medepalli, Kantha; Masuda, Kohei; Li, Na; Kopras, Elizabeth J; Kwiatkowski, David J; Borchers, Michael T; Wikenheiser-Brokamp, Kathryn A; Osterburg, Andrew; Mays, Maxwell; Sun, Yang; Plas, David R; Sun, Julia L; Franz, David N; Capal, Jamie K; Alayev, Anya; Holz, Marina K; Krueger, Darcy A; Siroky, Brian J; Yu, Jane J 2017. Tuberin Regulates Prostaglandin Receptor-mediated Viability, via Rheb, in mTORC1-hyperactive Cells. Molecular cancer research : MCR, , Lu, Calvin; Lee, Hye-Seung; Pappas, George P; Dilling, Daniel F; Burger, Charles D; Shifren, Adrian; Veeraraghavan, Srihari; Chapman, Jeffrey T; Parambil, Joseph; Ruoss, Stephen J; Young, Lisa R; Hammes, Stephen R; Kopras, Elizabeth J; Roads, Tammy; Krischer, Jeffrey P; McCormack, Francis X 2017. A Phase II Clinical Trial of an Aromatase Inhibitor for Postmenopausal Women with Lymphangioleiomyomatosis. Annals of the American Thoracic Society, 14 6, 919-928Oster, Robert A; Lindsell, Christopher J; Welty, Leah J; Mazumdar, Madhu; Thurston, Sally W; Rahbar, Mohammad H; Carter, Rickey E; Pollock, Bradley H; Cucchiara, Andrew J; Kopras, Elizabeth J; Jovanovic, Borko D; Enders, Felicity T 2015. Assessing statistical competencies in clinical and translational science education: one size does not fit all. Clinical and translational science, 8 1, 32-42Kopras, Elizabeth; Potluri, Veena; Bermudez, Mei-Ling; Williams, Karin; Belcher, Scott; Kasper, Susan 2014. Actions of endocrine-disrupting chemicals on stem/progenitor cells during development and disease. Endocrine-related cancer, 21 2, T1-12Haynes, Erin N; Beidler, Caroline; Wittberg, Richard; Meloncon, Lisa; Parin, Megan; Kopras, Elizabeth J; Succop, Paul; Dietrich, Kim N 2011. Developing a bidirectional academic-community partnership with an Appalachian-American community for environmental health research and risk communication. Environmental health perspectives, 119 10, 1364-72Dwivedi, Alok Kumar; Dwivedi, Sada Nand; Deo, Suryanarayana; Shukla, Rakesh; Kopras, Elizabeth 2010. Statistical models for predicting number of involved nodes in breast cancer patients. Health, 2 7, 641-651Dixon, Kathleen; Kopras, Elizabeth 2004. Genetic alterations and DNA repair in human carcinogenesis. Seminars in cancer biology, 14 6, 441-8Ulrich, C D; Kopras, E; Wu, Y; Ward, S 2000. Hereditary pancreatitis: epidemiology, molecules, mutations, and models. The Journal of laboratory and clinical medicine, 136 4, 260-74Ulrich, C D; Wood, P; Hadac, E M; Kopras, E; Whitcomb, D C; Miller, L J 1998. Cellular distribution of secretin receptor expression in rat pancreas. The American journal of physiology, 275 6 Pt 1, G1437-44Jiang, S; Kopras, E; McMichael, M; Bell, R H; Ulrich, C D 1997. Vasoactive intestinal peptide (VIP) stimulates in vitro growth of VIP-1 receptor-bearing human pancreatic adenocarcinoma-derived cells. Cancer research, 57 8, 1475-80Katoh, Y; Loukianov, E; Kopras, E; Zilberman, A; Periasamy, M 1994. Identification of functional promoter elements in the rabbit smooth muscle myosin heavy chain gene. The Journal of biological chemistry, 269 48, 30538-45
Astrinidis, Aristotelis; Li, Chenggang; Zhang, Erik Y; Zhao, Xueheng; Zhao, Shuyang; Guo, Minzhe; Olatoke, Tasnim; Mattam, Ushodaya; Huang, Rong; Zhang, Alan G; Pitstick, Lori; Kopras, Elizabeth J; Gupta, Nishant; Jandarov, Roman; Smith, Eric P; Fugate, Elizabeth; Lindquist, Diana; Markiewski, Maciej M; Karbowniczek, Magdalena; Wikenheiser-Brokamp, Kathryn A; Setchell, Kenneth D R; McCormack, Francis X; Xu, Yan; Yu, Jane J 2023. Upregulation of acid ceramidase contributes to tumor progression in tuberous sclerosis complex. JCI insight, 8 9, Du, Yina; Guo, Minzhe; Wu, Yixin; Wagner, Andrew; Perl, Anne Karina; Wikenheiser-Brokamp, Kathryn; Yu, Jane; Gupta, Nishant; Kopras, Elizabeth; Krymskaya, Vera; Obraztsova, Kseniya; Tang, Yan; Kwiatkowski, David; Henske, Elizabeth P; McCormack, Francis; Xu, Yan 2023. Lymphangioleiomyomatosis (LAM) Cell Atlas. Thorax, 78 1, 85-87Gupta, Nishant; Zhang, Bin; Zhou, Yuan; McCormack, Francis X; Ingledue, Rebecca; Robbins, Nathan; Kopras, Elizabeth J; McMahan, Susan; Singla, Abhishek; Swigris, Jeffrey; Cole, Adam G; Holz, Marina K 2023. Safety and efficacy of combined resveratrol and sirolimus in lymphangioleiomyomatosis. Chest, , Olatoke, Tasnim; Wagner, Andrew; Astrinidis, Aristotelis; Zhang, Erik Y; Guo, Minzhe; Zhang, Alan G; Mattam, Ushodaya; Kopras, Elizabeth J; Gupta, Nishant; Smith, Eric P; Karbowniczek, Magdalena; Markiewski, Maciej M; Wikenheiser-Brokamp, Kathryn A; Whitsett, Jeffrey A; McCormack, Francis X; Xu, Yan; Yu, Jane J 2023. Single-cell multiomic analysis identifies a HOX-PBX gene network regulating the survival of lymphangioleiomyomatosis cells. Science advances, 9 19, eadf8549Uehara, Yasuaki; Tanaka, Yusuke; Zhao, Shuyang; Nikolaidis, Nikolaos M; Pitstick, Lori B; Wu, Huixing; Yu, Jane J; Zhang, Erik; Hasegawa, Yoshihiro; Noel, John G; Gardner, Jason C; Kopras, Elizabeth J; Haffey, Wendy D; Greis, Kenneth D; Guo, Jinbang; Woods, Jason C; Wikenheiser-Brokamp, Kathryn A; Kyle, Jennifer E; Ansong, Charles; Teitelbaum, Steven L; Inoue, Yoshikazu; Altinişik, Göksel; Xu, Yan; McCormack, Francis X 2023. Insights into pulmonary phosphate homeostasis and osteoclastogenesis emerge from the study of pulmonary alveolar microlithiasis. Nature communications, 14 1, 1205Cortinas, Noella; Liu, Jie; Kopras, Elizabeth; Memon, Humna; Burkes, Robert; Gupta, Nishant 2022. Impact of Age, Menopause, and Sirolimus on Spontaneous Pneumothoraces in Lymphangioleiomyomatosis. Chest, , Hudock, K M; Collins, M S; Imbrogno, M A; Kramer, E L; Brewington, J J; Ziady, A; Zhang, N; Snowball, J; Xu, Y; Carey, B C; Horio, Y; O'Grady, S M; Kopras, E J; Meeker, J; Morgan, H; Ostmann, A J; Skala, E; Siefert, M E; Na, C L; Davidson, C R; Gollomp, K; Mangalmurti, N; Trapnell, B C; Clancy, J P 2022. Alpha-1 antitrypsin limits neutrophil extracellular trap disruption of airway epithelial barrier function. Frontiers in immunology, 13 , 1023553Jose, Arun; Kopras, Elizabeth J; Shah, Shimul A; Elwing, Jean M 2022. Portopulmonary Hypertension Practice Patterns after Liver Transplantation. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, , Shaw, Brian M; Kopras, Elizabeth; Gupta, Nishant 2022. Menstrual Cycle-Related Respiratory Symptom Variability in Patients with Lymphangioleiomyomatosis. Annals of the American Thoracic Society, , Guo, Minzhe; Yu, Jane J; Perl, Anne Karina; Wikenheiser-Brokamp, Kathryn A; Riccetti, Matt; Zhang, Erik Y; Sudha, Parvathi; Adam, Mike; Potter, Andrew; Kopras, Elizabeth J; Giannikou, Krinio; Potter, S Steven; Sherman, Sue; Hammes, Stephen R; Kwiatkowski, David J; Whitsett, Jeffrey A; McCormack, Francis X; Xu, Yan 2020. Single Cell Transcriptomic Analysis Identifies a Unique Pulmonary Lymphangioleiomyomatosis Cell. American journal of respiratory and critical care medicine, , Hudock, Kristin M; Collins, Margaret S; Imbrogno, Michelle; Snowball, John; Kramer, Elizabeth L; Brewington, John J; Gollomp, Kandace; McCarthy, Cormac; Ostmann, Alicia J; Kopras, Elizabeth J; Davidson, Cynthia R; Srdiharan, Anusha; Arumugam, Paritha; Sengupta, Shaon; Xu, Yan; Worthen, G Scott; Trapnell, Bruce C; Clancy, John Paul 2020. Neutrophil extracellular traps activate IL-8 and IL-1 expression in human bronchial epithelia. American journal of physiology. Lung cellular and molecular physiology, , Lu, Yiyang; Liu, Xiaolei; Zhang, Erik; Kopras, Elizabeth J; Smith, Eric P; Astreinidis, Aristotelis; Li, Chenggang; Leung, Yuet-Kin; Ho, Shuk-Mei; Yu, Jane J 2020. Estrogen activates pyruvate kinase M2 and increases the growth of TSC2-deficient cells. PloS one, 15 2, e0228894Jönsson, Åsa Lina M; Bendstrup, Elisabeth; Mogensen, Susie; Kopras, Elizabeth J; McCormack, Francis X; Campo, Ilaria; Mariani, Francesca; Escribano-Montaner, Amparo; Holm, Are M; Del Mar Martinez-Colls, Maria; Pintos-Morell, Guillem; Taillé, Camille; Crestani, Bruno; Hilberg, Ole; Hvarregaard Christensen, Jane; Simonsen, Ulf 2019. Eight novel variants in the SLC34A2 gene in pulmonary alveolar microlithiasis. The European respiratory journal, , Singla, Abhishek; Kopras, Elizabeth J; Gupta, Nishant 2019. Spontaneous pneumothorax and air travel in Pulmonary Langerhans cell histiocytosis: A patient survey. Respiratory investigation, 57 6, 582-589Eckman, Mark H; Kopras, Elizabeth J; Montag-Leifling, Karen; Kirby, Lari P; Burns, Lisa; Indihar, Veronica M; Joseph, Patricia M 2017. Shared Decision-Making Tool for Self-Management of Home Therapies for Patients With Cystic Fibrosis. MDM policy & practice, 2 1, 2381468317715621Gupta, Nishant; Kopras, Elizabeth J; Henske, Elizabeth P; James, Laura E; El-Chemaly, Souheil; Veeraraghavan, Srihari; Drake, Matthew G; McCormack, Francis X 2017. Spontaneous Pneumothoraces in Patients with Birt-Hogg-Dubé Syndrome. Annals of the American Thoracic Society, 14 5, 706-713Li, Chenggang; Liu, Xiaolei; Liu, Yang; Zhang, Erik; Medepalli, Kantha; Masuda, Kohei; Li, Na; Kopras, Elizabeth J; Kwiatkowski, David J; Borchers, Michael T; Wikenheiser-Brokamp, Kathryn A; Osterburg, Andrew; Mays, Maxwell; Sun, Yang; Plas, David R; Sun, Julia L; Franz, David N; Capal, Jamie K; Alayev, Anya; Holz, Marina K; Krueger, Darcy A; Siroky, Brian J; Yu, Jane J 2017. Tuberin Regulates Prostaglandin Receptor-mediated Viability, via Rheb, in mTORC1-hyperactive Cells. Molecular cancer research : MCR, , Lu, Calvin; Lee, Hye-Seung; Pappas, George P; Dilling, Daniel F; Burger, Charles D; Shifren, Adrian; Veeraraghavan, Srihari; Chapman, Jeffrey T; Parambil, Joseph; Ruoss, Stephen J; Young, Lisa R; Hammes, Stephen R; Kopras, Elizabeth J; Roads, Tammy; Krischer, Jeffrey P; McCormack, Francis X 2017. A Phase II Clinical Trial of an Aromatase Inhibitor for Postmenopausal Women with Lymphangioleiomyomatosis. Annals of the American Thoracic Society, 14 6, 919-928Oster, Robert A; Lindsell, Christopher J; Welty, Leah J; Mazumdar, Madhu; Thurston, Sally W; Rahbar, Mohammad H; Carter, Rickey E; Pollock, Bradley H; Cucchiara, Andrew J; Kopras, Elizabeth J; Jovanovic, Borko D; Enders, Felicity T 2015. Assessing statistical competencies in clinical and translational science education: one size does not fit all. Clinical and translational science, 8 1, 32-42Kopras, Elizabeth; Potluri, Veena; Bermudez, Mei-Ling; Williams, Karin; Belcher, Scott; Kasper, Susan 2014. Actions of endocrine-disrupting chemicals on stem/progenitor cells during development and disease. Endocrine-related cancer, 21 2, T1-12Haynes, Erin N; Beidler, Caroline; Wittberg, Richard; Meloncon, Lisa; Parin, Megan; Kopras, Elizabeth J; Succop, Paul; Dietrich, Kim N 2011. Developing a bidirectional academic-community partnership with an Appalachian-American community for environmental health research and risk communication. Environmental health perspectives, 119 10, 1364-72Dwivedi, Alok Kumar; Dwivedi, Sada Nand; Deo, Suryanarayana; Shukla, Rakesh; Kopras, Elizabeth 2010. Statistical models for predicting number of involved nodes in breast cancer patients. Health, 2 7, 641-651Dixon, Kathleen; Kopras, Elizabeth 2004. Genetic alterations and DNA repair in human carcinogenesis. Seminars in cancer biology, 14 6, 441-8Ulrich, C D; Kopras, E; Wu, Y; Ward, S 2000. Hereditary pancreatitis: epidemiology, molecules, mutations, and models. The Journal of laboratory and clinical medicine, 136 4, 260-74Ulrich, C D; Wood, P; Hadac, E M; Kopras, E; Whitcomb, D C; Miller, L J 1998. Cellular distribution of secretin receptor expression in rat pancreas. The American journal of physiology, 275 6 Pt 1, G1437-44Jiang, S; Kopras, E; McMichael, M; Bell, R H; Ulrich, C D 1997. Vasoactive intestinal peptide (VIP) stimulates in vitro growth of VIP-1 receptor-bearing human pancreatic adenocarcinoma-derived cells. Cancer research, 57 8, 1475-80Katoh, Y; Loukianov, E; Kopras, E; Zilberman, A; Periasamy, M 1994. Identification of functional promoter elements in the rabbit smooth muscle myosin heavy chain gene. The Journal of biological chemistry, 269 48, 30538-45