Publications

Below are some selected publications since 2010

1. Dong M, Yan S, Chen Y, Niklewski PJ, Sun X, Chenault K & Wang H-S (2010). Role of the transient outward current in regulating myocyte mechanical properties. J Cardiovasc Electrophysiol 21, 697-703. PMID: 20132386
2. Dong M, Niklewski, PJ & Wang H-S (2011). Ionic basis of cellular electrical and mechanical abnormalities in Brugada syndrome. Am J Physiol Heart Circ Physiol 300, H279-H287. PMID: 20935153
3. Wang H-S, Arvanitis D, Dong M, Niklewski PJ, Zhao W, Kranias EG & Sanoudou D (2011). SERCA2a superinhibition by human phospholamban triggers electrical and structural remodelling in mouse hearts. Physiol Genomics 43, 357-364. PMID: 21266500
4. Yan S, Chen Y, Dong M, Song W, Belcher SM & Wang H-S (2011). Bisphenol A and 17β-estradiol promote arrhythmia in the female heart via alteration of calcium handling. PLoS ONE 6(9): e25455. PMID:21980463

   (Recognized as among the top 10% most cited PLoS ONE articles as of June 2017)

5. Belcher SM, Chen Y, Yan S & Wang H-S (2012). Rapid estrogen receptor-mediated mechanisms determine the sexually dimorphic sensitivity of ventricular myocytes to 17b-estradiol and the environmental endocrine disruptor bisphenol A. Endocrinology 153, 712-720. PMID:22166976
6. Yan S, Song W, Chen Y, Hong K, Rubinstein J & Wang H-S (2013). Low-dose bisphenol A and estrogen increase ventricular arrhythmias following ischemia-reperfusion in female rat hearts. Food Chem Toxcol 56, 75-80. PMID: 23429042
7. Gao X, Liang Q, Chen Y & Wang H-S (2013). Molecular mechanisms underlying the rapid arrhythmogenic action of bisphenol A in female rat hearts. Endocrinology 154, 4607-4617. PMID:24140712
8. Liang Q, Gao X, Chen Y, Hong K & Wang H-S (2014). Cellular mechanism of the nonmonotonic dose response of bisphenol A in rat cardiac myocytes. Environ Health Perspect 122, 601-608. PMID:24569941
9. Gao X & Wang H-S (2014). Impact of bisphenol A on the cardiovascular system – Epidemiological and experimental evidence and molecular mechanisms. Int J Environ Res Public Health 11, 8399-8413. PMID:25153468
10. Wang H-S, Chen Y, Vairamani K & Shull GE (2014). Critical role of bicarbonate and bicarbonate transporters in cardiac function. World J Biol Chem 5, 334-345. PMID:25225601
11. Gao X, Ma J, Chen Y & Wang H-S (2015). Rapid responses and mechanism of action for low-dose bisphenol S on ex vivo rat hearts and isolated myocytes: evidence of female-specific proarrhythmic effects. Environ Health Perspect 123, 571-578. PMID: 4455592

    (Featured in News/Science Selections, EHP, http://dx.doi.org/10.1289/ehp.123-A157)

12. Ma J, Hong K & Wang H-S (2017). Progesterone protects against BPA-induced arrhythmias in female rat cardiac myocytes via rapid signaling. Endocrinology 158, 778-790. PMID:28324061
13. Vought V & Wang H-S (2018). Impact of common environmental chemicals bisphenol A and bisphenol S on the physiology of Lumbriculus variegatus. Environ Toxicol Pharmacol 60, 225-229. PMID:29763883
14. Holmes R, Ma J, Andra SS & Wang H-S (2021). Effect of common consumer washing methods on bisphenol A release. Chemosphere 277. 130355. https://doi.org/10.1016/j.chemosphere.2021.130355

Below are some examples of the media coverage of our works. These are lay level articles that can give you an introduction of the works in our lab:

Women’s Health (July 22, 2014), “BPA substitute may pose toxic to heart health”

Science Daily (June 23, 2014), “Common BPA substitute, BPS, disrupts heart rhythms in females”

Consumer Affairs (June 26, 2014), “More research links BPA to health issues”

National News (Aug 9, 2014), “Many BPA-free bottles contain a chemical that causes arrhythmia, hyperactivity and brain changes”

Scientific American (Aug 11, 2014), “BPA-free plastic containers may be just as hazardous”

National Geographic (Feb 26, 2015), “Chemical in BPA-free products linked to irregular heartbeats”

Environ Health Perspect (June, 2015), News/Science Selections – “Comparing BPS and BPA, cardiovascular effects in female rat hearts”, Vol. 123 no. 6 pp. A157

The New York Times (June 15, 2015), “Facing consumer pressure, companies start to seek safe alternatives to BPA”