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Photo of  Hani Kushlaf, MD

Hani Kushlaf, MD

Associate Professor of Clinical

Director of the Neuromuscular Medicine Fellowship, Director of Neuromuscular Research

Neurology and Rehabilitation Medicine | College of Medicine

Education/Credentials
  • Fellowship: Duke University Medical Center (Advanced Neuromuscular Medicine)
  • Fellowship: Mayo Clinic (Peripheral Nerve Disorders)
  • Fellowship: Mayo Clinic (Muscle Disease )
  • Residency: University of Kentucky (Neurology- Chief Resident)
  • Residency: University of Kentucky (Neurology)
  • Internship: University of Kentucky (Internal Medicine)
  • Medical Degree: University of Tripoli School of Medicine
Board Certifications & Licenses

American Board of Electrodiagnostic Medicine (Certification Date: 20130413)
American Board of Psychiatry and Neurology (Neurology) (Certification Date: 20090928) - (Recertification Date: 20191215)
American Board of Psychiatry and Neurology (Neuromuscular Medicine) (Certification Date: 20110815)
United Council for Neurologic Subspecialties (Certification Date: 20150815)

Languages

Arabic

Specialties

Clinical Neuromuscular Pathology
Electrodiagnostic Medicine
Neurology
Neuromuscular Medicine

Contact Information
Research Interests

-Inherited and acquired peripheral neuropathies (including CIDP and other dysimmune neuropathies), plexopathies, myopathies, muscular dystrophies, ALS, motor neuron disorders, and neuromuscular junction disorders (myasthenia gravis and Lambert-Eaton myasthenic syndrome)
-Inclusion body myositis
-Peripheral nerve and muscle ultrasound
-Single fiber EMG and advanced EMG techniques (MUNE, MUP analysis)
-Pathology of nerve and muscle disorders
 

Clinical Interests

Neurology

Acute Inflammatory Demyelinating Polyradiculoneuropathy

Alcoholic Neuropathy

ALS (Lou Gehrig's Disease)

Amyloid Neuropathies

Atrophic Muscular Disorders

Autonomic Neuropathy

Brachial Plexus Injury

Brachial Plexus Neuropathies

Chronic Inflammatory Demyelinating Polyradiculoneuropathy

Congenital Myasthenic Syndromes (CMS)

Diabetic Neuropathies

Distal Myopathies

Duchenne Muscular Dystrophy

Facioscapulohumeral Muscular Dystrophy

Foot Drop

Frontalis Interna Hyperostosis

Hyperkalemic Periodic Paralysis

Hypokalemic Periodic Paralysis

Isaacs Syndrome

Kearns-Sayre Syndrome

Limb-Girdle Muscular Dystrophies

Mad Cow Disease (Creutzfeldt-Jakob disease)

MELAS Syndrome

Memory Disorders

MERRF Syndrome

Metabolic Brain Disease

Mild Cognitive Impairment

Mitochondrial Myopathies

Mononeuropathies

Motor Neuron Disease

Muscle Hypertonia

Muscle Weakness

Muscular Atrophy

Myasthenia Gravis

Myopathy

Myophosphorylase Deficiency (McArdle Disease)

Myositis

Myotonia

Myotonia Congenita

Myotonic Disorders

Myotonic Dystrophy

Nemaline Myopathies

Nerve Compression Syndromes

Nerve Pain

Nerve Pain Syndromes

Neuritis

Neurofibroma

Neurofibromatosis

Neurofibromatosis II

Neurogenic Inflammation

Neuromuscular Disease

Neuromuscular Disorders

Neuromuscular Junction Disease

Neuromuscular Manifestations

Occupational Neuropathies

Paraneoplastic Polyneuropathy

Peripheral Nerve Disorders

Peripheral Nerve Injury

Peripheral Nervous System Disease

Peripheral Neuropathy

Peroneal Neuropathy

Polyneuropathies

Polyradiculoneuropathy

Polyradiculopathy

Radiculopathies

Radiculopathy

Sarcoglycanopathies

Sciatic Neuropathy

Sciatica

Peer Reviewed Publications

Hafeez, Komal; Kushlaf, Hani; Al-Sultani, Husam; Joseph, Anny-Claude; Zaeem, Zoya; Siddiqi, Zaeem; Laboy, Shannon; Pulley, Michael; Habib, Ali A; Robbins, Nathaniel M; Zadeh, Sean; Hafeez, Muhammad Ubaid; Hussain, Yessar; Melendez-Zaidi, Alexandria; Kassardjian, Charles; Johnson, Kristin; Leonhard, Holly; Biliciler, Suur; Patino Murillas, Jorge E; Shaibani, Aziz I 2022. Patient preference for virtual versus in-person visits in neuromuscular clinical practice. Muscle & nerve, ,

Korb, Manisha; Peck, Allison; Alfano, Lindsay N; Berger, Kenneth I; James, Meredith K; Ghoshal, Nupur; Healzer, Elise; Henchcliffe, Claire; Khan, Shaida; Mammen, Pradeep P A; Patel, Sujata; Pfeffer, Gerald; Ralston, Stuart H; Roy, Bhaskar; Seeley, William W; Swenson, Andrea; Mozaffar, Tahseen; Weihl, Conrad; Kimonis, Virginia 2022. Development of a standard of care for patients with valosin-containing protein associated multisystem proteinopathy. Orphanet journal of rare diseases, 17 1, 23

Kushlaf, Hani 2022. The applicability of the myasthenia gravis patient registry data to disease burden and medication changes in clinical practice. Muscle & nerve, ,

Schiava, Marianela; Ikenaga, Chiseko; Villar-Quiles, Rocío Nur; Caballero-Ávila, Marta; Topf, Ana; Nishino, Ichizo; Kimonis, Virginia; Udd, Bjarne; Schoser, Benedikt; Zanoteli, Edmar; Souza, Paulo Victor Sgobbi; Tasca, Giorgio; Lloyd, Thomas; Lopez-de Munain, Adolfo; Paradas, Carmen; Pegoraro, Elena; Nadaj-Pakleza, Aleksandra; De Bleecker, Jan; Badrising, Umesh; Alonso-Jiménez, Alicia; Kostera-Pruszczyk, Anna; Miralles, Francesc; Shin, Jin-Hong; Bevilacqua, Jorge Alfredo; Olivé, Montse; Vorgerd, Matthias; Kley, Rudi; Brady, Stefen; Williams, Timothy; Domínguez-González, Cristina; Papadimas, George K; Warman, Jodi; Claeys, Kristl G; de Visser, Marianne; Muelas, Nuria; LaForet, Pascal; Malfatti, Edoardo; Alfano, Lindsay N; Nair, Sruthi S; Manousakis, Georgios; Kushlaf, Hani A; Harms, Matthew B; Nance, Christopher; Ramos-Fransi, Alba; Rodolico, Carmelo; Hewamadduma, Channa; Cetin, Hakan; García-García, Jorge; Pál, Endre; Farrugia, Maria Elena; Lamont, Phillipa J; Quinn, Colin; Nedkova-Hristova, Velina; Peric, Stojan; Luo, Sushan; Oldfors, Anders; Taylor, Kate; Ralston, Stuart; Stojkovic, Tanya; Weihl, Conrad; Diaz-Manera, Jordi 2022. Genotype-phenotype correlations in valosin-containing protein disease: a retrospective muticentre study. Journal of neurology, neurosurgery, and psychiatry, ,

Bazrafshan, Sholeh; Kushlaf, Hani; Kakroo, Mashhood; Quinlan, John; Becker, Richard C; Sadayappan, Sakthivel 2021. Genetic Modifiers of Hereditary Neuromuscular Disorders and Cardiomyopathy. Cells, 10 2,

Diaz-Manera, Jordi; Kishnani, Priya S; Kushlaf, Hani; Ladha, Shafeeq; Mozaffar, Tahseen; Straub, Volker; Toscano, Antonio; van der Ploeg, Ans T; Berger, Kenneth I; Clemens, Paula R; Chien, Yin-Hsiu; Day, John W; Illarioshkin, Sergey; Roberts, Mark; Attarian, Shahram; Borges, Joao Lindolfo; Bouhour, Francoise; Choi, Young Chul; Erdem-Ozdamar, Sevim; Goker-Alpan, Ozlem; Kostera-Pruszczyk, Anna; Haack, Kristina An; Hug, Christopher; Huynh-Ba, Olivier; Johnson, Judith; Thibault, Nathan; Zhou, Tianyue; Dimachkie, Mazen M; Schoser, Benedikt 2021. Safety and efficacy of avalglucosidase alfa versus alglucosidase alfa in patients with late-onset Pompe disease (COMET): a phase 3, randomised, multicentre trial. The Lancet. Neurology, 20 12, 1012-1026

Kushlaf, Hani 2021. Immune Profiling Beyond Antibodies in Double Seronegative and Acetylcholine Receptor Antibody Positive Myasthenia Gravis: What do we Learn? Muscle & nerve, ,

Kushlaf, Hani; Ezzat, Kariem 2021. Extracellular amyloid deposition in sporadic inclusion body myositis: Further insights. Muscle & nerve, 64 5, 517-519

Kushlaf, Hani; Li, Yuebing 2021. How does rituximab fit in the treatment algorithm of myasthenia gravis? Muscle & nerve, 64 6, 635-636

Sandrone, Stefano; Albert, Dara Vf; Dunham, S Richard; Kraker, Jessica; Noviawaty, Ika; Palm, Michael; Kushlaf, Hani 2021. Training in Neurology: How Lessons Learned on Teaching, Well-being and Telemedicine During the COVID-19 Pandemic Can Shape the Future of Neurology Education. Neurology, ,

Schoser, Benedikt; Roberts, Mark; Byrne, Barry J; Sitaraman, Sheela; Jiang, Hai; Laforêt, Pascal; Toscano, Antonio; Castelli, Jeff; Díaz-Manera, Jordi; Goldman, Mitchell; van der Ploeg, Ans T; Bratkovic, Drago; Kuchipudi, Srilakshmi; Mozaffar, Tahseen; Kishnani, Priya S 2021. Safety and efficacy of cipaglucosidase alfa plus miglustat versus alglucosidase alfa plus placebo in late-onset Pompe disease (PROPEL): an international, randomised, double-blind, parallel-group, phase 3 trial. The Lancet. Neurology, 20 12, 1027-1037

Barohn, Richard J; Gajewski, Byron; Pasnoor, Mamatha; Brown, Alexandra; Herbelin, Laura L; Kimminau, Kim S; Mudaranthakam, Dinesh Pal; Jawdat, Omar; Dimachkie, Mazen M ; Iyadurai, Stanley; Stino, Amro; Kissel, John; Pascuzzi, Robert; Brannagan, Thomas; Wicklund, Matthew; Ahmed, Aiesha; Walk, David; Smith, Gordon; Quan, Dianna; Heitzman, Darryl; Tobon, Alejandro; Ladha, Shafeeq; Wolfe, Gil; Pulley, Michael; Hayat, Ghazala; Li, Yuebing; Thaisetthawatkul, Pariwat; Lewis, Richard; Biliciler, Suur; Sharma, Khema; Salajegheh, Kian; Trivedi, Jaya; Mallonee, William; Burns, Ted; Jacoby, Mark; Bril, Vera; Vu, Tuan; Ramchandren, Sindhu; Bazant, Mark; Austin, Sara; Karam, Chafic; Hussain, Yessar; Kutz, Christen; Twydell, Paul; Scelsa, Stephen; Kushlaf, Hani; Wymer, James; Hehir, Michael; Kolb, Noah; Ralph, Jeffrey; Barboi, Alexandru; Verma, Navin; Ahmed, Moiz; Memon, Anza; Saperstein, David; Lou, Jau-Shin; Swenson, Andrea; Cash, Tiyonnoh 2020. Patient Assisted Intervention for Neuropathy: Comparison of Treatment in Real Life Situations (PAIN-CONTRoLS): Bayesian Adaptive Comparative Effectiveness Randomized Trial. JAMA neurology, ,

Janecek, Jacqueline; Kushlaf, Hani 2020. Toxin-Induced Channelopathies, Neuromuscular Junction Disorders, and Myopathy. Neurologic clinics, 38 4, 765-780

Kushlaf, Hani 2020. DIVING INTO THE HETEROGENEITY OF INCLUSION BODY MYOSITIS. Muscle & nerve, ,

Kushlaf, Hani 2020. COVID-19 in muscle-specific kinase myasthenia gravis: A case report. Muscle & nerve, ,

Kushlaf, Hani 2020. Cystinosis myopathy: Searching for optimal clinical outcome measures. Muscle & nerve, ,

Kushlaf, Hani 2019. Peripheral Neuropathy and the Ceruloplasmin Gene. Annals of internal medicine, 170 4, 282

Kushlaf, Hani; Li, Yuebing 2019. The evidence is stacked against thymectomy in MuSK myasthenia gravis. Muscle & nerve, ,

Sandrone, Stefano; Berthaud, Jimmy V; Chuquilin, Miguel; Cios, Jacquelyne; Ghosh, Pritha; Gottlieb-Smith, Rachel J; Kushlaf, Hani; Mantri, Sneha; Masangkay, Neil; Menkes, Daniel L; Nevel, Kathryn S; Sarva, Harini; Schneider, Logan D 2019. Neurologic and neuroscience education: Mitigating neurophobia to mentor health care providers. Neurology, 92 4, 174-179

Davalos, Long; Kushlaf, Hani 2018. New onset of seropositive generalized myasthenia gravis following intravesical Bacille Calmette-Guerin treatment for bladder cancer: A case study. Muscle & nerve, ,

Lee, Ikjae; Kushlaf, Hani 2018. Needle electromyography practice patterns in patients taking novel oral anticoagulants: A survey-based study. Muscle & nerve, ,

Kushlaf, Hani A; Massey, E Wayne; Hobson-Webb, Lisa 2014. Proximal Median Neuropathy caused by Surgical Manipulation of Masson Tumor. Muscle & nerve, ,

Erra, Carmen; Granata, Giuseppe; Liotta, Giovanna; Podnar, Simon; Giannini, Mauro; Kushlaf, Hani; Hobson-Webb, Lisa D; Leversedge, Fraser J; Martinoli, Carlo; Padua, Luca 2013. Ultrasound diagnosis of bony nerve entrapment: case series and literature review. Muscle & nerve, 48 3, 445-50

Kushlaf, Hani A 2013. Emerging toxic neuropathies and myopathies. The Psychiatric clinics of North America, 36 2, 209-18

Kushlaf, Hani A 2011. Emerging toxic neuropathies and myopathies. Neurologic clinics, 29 3, 679-87

Kushlaf H. 12-01-2009. Toxic myopathies Clinical Neurotoxicology: Syndromes, Substances, Environments, , 159-173

Kushlaf H. 08-01-2021. Update on the Diagnostic and Therapeutic Landscape of Sporadic Inclusion Body Myositis Current Treatment Options in Neurology, 23 8,

Kushlaf H.A. 06-18-2009. Toxic Myopathies Clinical Neurotoxicology: Syndromes, Substances, Environments, Expert Consult - Online and Print, , 159-173

Abstract Publications

Hani Kushlaf, Vern Juel, Lisa Hobson-Webb 10-2012. Sonographically-measured nerve size and intra-nerve size variability in inflammatory polyneueropathy Muscle&Nerve and Clinical Neurophysiology, ,


Hani Kushlaf, Vern Juel, Lisa Hobson-Webb 10-2012. Do ultrasound characteristics correlate with electrodiagnostic findings in inflammatory neuropathies? Muscle&Nerve and Clinical Neurophysiology, ,


David Clark, Hani Kushlaf 10-16-2013. Macroglossia in Duchenne Muscular Dystrophy Muscle&Nerve and Clinical Neurophysiology, ,


Julia Zhu, Hani Kushlaf 03-16-2014. Camptocormia as the Initial Prominent Manifestation of Myotonic Dystrophy Type I , ,


Jonas Vanags, Hani Kushlaf, Vern Juel 02-2012. Post-irradiation hypoglossal and accessory neuropathies with myokymic discharges North Carolina Neurological society annual meeting, ,