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Lisa Martin

Research Interests

Dr. Lisa J. Martin is an internationally recognized genetic epidemiologist.  Dr. Martin is currently an Associate Professor of Pediatrics Cincinnati Children’s Hospital Medical Center in the Divisions of Human Genetics and Biostatistics and Epi...

Education/Credentials
  • B.A. : University of Kansas
  • M.A. : University of Kansas
  • Ph.D. : University of Kansas
Contact Information

Peer Reviewed Publications

Baye, T. M.; Butsch Kovacic, M.; Biagini Myers, J. M.; Martin, L. J.; Lindsey, M.; Patterson, T. L.; He, H.; Ericksen, M. B.; Gupta, J.; Tsoras, A. M.; Lindsley, A.; Rothenberg, M. E.; Wills-Karp, M.; Eissa, N. T.; Borish, L.; Khurana Hershey, G. K. 2011. Differences in Candidate Gene Association between European Ancestry and African American Asthmatic Children , 6 2 , e16522

Rieley, M. B.; Stevenson, D. A.; Viskochil, D. H.; Tinkle, B. T.; Martin, L. J.; Schorry, E. K. 2011. Variable expression of neurofibromatosis 1 in monozygotic twins , 21 11 , 1829-33

Benson, D. W.; Martin, L. J. 2010. Complex story of the genetic origins of pediatric heart disease , 121 11 , 1277-9

Blanchard, C.; Stucke, E. M.; Burwinkel, K.; Caldwell, J. M.; Collins, M. H.; Ahrens, A.; Buckmeier, B. K.; Jameson, S. C.; Greenberg, A.; Kaul, A.; Franciosi, J. P.; Kushner, J. P.; Martin, L. J.; Putnam, P. E.; Abonia, J. P.; Wells, S. I.; Rothenberg, M. E. 2010. Coordinate interaction between IL-13 and epithelial differentiation cluster genes in eosinophilic esophagitis , 184 7 , 4033-41

Bollepalli, S.; Dolan, L. M.; Deka, R.; Martin, L. J. 2010. Association of FTO Gene Variants With Adiposity in African-American Adolescents , 184 7 , 4033-41

Doughty Rice, C.; Ruschman, J. G.; Martin, L. J.; Manders, J. B.; Miller, E. 2010. Retrospective comparison of patient outcomes after in-person and telephone results disclosure counseling for BRCA1/2 genetic testing , 9 2 , 203-12

Martin, L. J.; Woo, J. G.; Morrison, J. A. 2010. Evidence of shared genetic effects between pre- and postobesity epidemic BMI levels , 18 7 , 1378-82

Rothenberg, M. E.; Spergel, J. M.; Sherrill, J. D.; Annaiah, K.; Martin, L. J.; Cianferoni, A.; Gober, L.; Kim, C.; Glessner, J.; Frackelton, E.; Thomas, K.; Blanchard, C.; Liacouras, C.; Verma, R.; Aceves, S.; Collins, M. H.; Brown-Whitehorn, T.; Putnam, P. E.; Franciosi, J. P.; Chiavacci, R. M.; Grant, S. F.; Abonia, J. P.; Sleiman, P. M.; Hakonarson, H. 2010. Common variants at 5q22 associate with pediatric eosinophilic esophagitis , 42 4 , 289-91

Sherrill, J. D.; Gao, P. S.; Stucke, E. M.; Blanchard, C.; Collins, M. H.; Putnam, P. E.; Franciosi, J. P.; Kushner, J. P.; Abonia, J. P.; Assa'ad, A. H.; Kovacic, M. B.; Biagini Myers, J. M.; Bochner, B. S.; He, H.; Hershey, G. K.; Martin, L. J.; Rothenberg, M. E. 2010. Variants of thymic stromal lymphopoietin and its receptor associate with eosinophilic esophagitis , 126 1 , 160-5 e3

Smith, E. M.; Zhang, Y.; Baye, T. M.; Gawrieh, S.; Cole, R.; Blangero, J.; Carless, M. A.; Curran, J. E.; Dyer, T. D.; Abraham, L. J.; Moses, E. K.; Kissebah, A. H.; Martin, L. J.; Olivier, M. 2010. INSIG1 influences obesity-related hypertriglyceridemia in humans , 51 4 , 701-8

Zarate, Y. A.; Martin, L. J.; Hopkin, R. J.; Bender, P. L.; Zhang, X.; Saal, H. M. 2010. Evaluation of growth in patients with isolated cleft lip and/or cleft palate , 125 3 , e543-9

Zhang, Y.; Smith, E. M.; Baye, T. M.; Eckert, J. V.; Abraham, L. J.; Moses, E. K.; Kissebah, A. H.; Martin, L. J.; Olivier, M. 2010. Serotonin (5-HT) receptor 5A sequence variants affect human plasma triglyceride levels , 149A 8 , 1691-7

Burrow, T. A.; Saal, H. M.; de Alarcon, A.; Martin, L. J.; Cotton, R. T.; Hopkin, R. J. 2009. Characterization of congenital anomalies in individuals with choanal atresia , 135 6 , 543-7

Cupples, L. A.; Beyene, J.; Bickeboller, H.; Daw, E. W.; Fallin, M. D.; Gauderman, W. J.; Ghosh, S.; Goode, E. L.; Hauser, E. R.; Hinrichs, A.; Kent, J. W., Jr.; Martin, L. J.; Martinez, M.; Neuman, R. J.; Province, M.; Szymczak, S.; Wilcox, M. A.; Ziegler, A.; Maccluer, J. W.; Almasy, L. 2009. Genetic Analysis Workshop 16: Strategies for genome-wide association study analyses , 3 Suppl 7 1 , S1

Hinton, R. B.; Martin, L. J.; Rame-Gowda, S.; Tabangin, M. E.; Cripe, L. H.; Benson, D. W. 2009. Hypoplastic left heart syndrome links to chromosomes 10q and 6q and is genetically related to bicuspid aortic valve , 53 12 , 1065-71

Martin, L. J.; Gao, G.; Kang, G.; Fang, Y.; Woo, J. G. 2009. Improving the signal-to-noise ratio in genome-wide association studies , 33 Suppl 1 5 , S29-32

Tabangin, M. E.; Woo, J. G.; Martin, L. J. 2009. The effect of minor allele frequency on the likelihood of obtaining false positives , 3 Suppl 7 Suppl 1 , S41

Urbina, E. M.; Khoury, P.; Martin, L. J.; D'Alessio, D.; Dolan, L. M. 2009. Gender differences in the relationships among obesity, adiponectin and brachial artery distensibility in adolescents and young adults , 33 10 , 1118-25

Woo, J. G.; Guerrero, M. L.; Altaye, M.; Ruiz-Palacios, G. M.; Martin, L. J.; Dubert-Ferrandon, A.; Newburg, D. S.; Morrow, A. L. 2009. Human milk adiponectin is associated with infant growth in two independent cohorts , 4 2 , 101-9

Zarate, Y. A.; Mena, R.; Martin, L. J.; Steele, P.; Tinkle, B. T.; Hopkin, R. J. 2009. Experience with hemihyperplasia and Beckwith-Wiedemann syndrome surveillance protocol , 149A 8 , 1691-7

Zhu, H. Y.; Wang, S. W.; Martin, L. J.; Liu, L.; Li, Y. H.; Chen, R.; Wang, L.; Zhang, M. L.; Benson, D. W. 2009. The role of mitochondrial genome in essential hypertension in a Chinese Han population , 149A 8 , 1691-7

North, K.E.; Martin, L. J. 2008. The Importance of GeneĆ¢??Environment Interaction: Implications for Social Scientists , 37 2 , 164-200

Broderick, P.; Carvajal-Carmona, L.; Pittman, A. M.; Webb, E.; Howarth, K.; Rowan, A.; Lubbe, S.; Spain, S.; Sullivan, K.; Fielding, S.; Jaeger, E.; Vijayakrishnan, J.; Kemp, Z.; Gorman, M.; Chandler, I.; Papaemmanuil, E.; Penegar, S.; Wood, W.; Sellick, G.; Qureshi, M.; Teixeira, A.; Domingo, E.; Barclay, E.; Martin, L.; Sieber, O.; Kerr, D.; Gray, R.; Peto, J.; Cazier, J. B.; Tomlinson, I.; Houlston, R. S. 2007. A genome-wide association study shows that common alleles of SMAD7 influence colorectal cancer risk , 39 11 , 1315-7

Cordell, H. J.; de Andrade, M.; Babron, M. C.; Bartlett, C. W.; Beyene, J.; Bickeboller, H.; Culverhouse, R.; Cupples, L. A.; Daw, E. W.; Dupuis, J.; Falk, C. T.; Ghosh, S.; Goddard, K. A.; Goode, E. L.; Hauser, E. R.; Martin, L. J.; Martinez, M.; North, K. E.; Saccone, N. L.; Schmidt, S.; Tapper, W.; Thomas, D.; Tritchler, D.; Vieland, V. J.; Wijsman, E. M.; Wilcox, M. A.; Witte, J. S.; Yang, Q.; Ziegler, A.; Almasy, L.; Maccluer, J. W. 2007. Genetic Analysis Workshop 15: gene expression analysis and approaches to detecting multiple functional loci , 1 Suppl 1 1 , S1

Crimmins, N. A.; Dolan, L. M.; Martin, L. J.; Bean, J. A.; Daniels, S. R.; Lawson, M. L.; Goodman, E.; Woo, J. G. 2007. Stability of adolescent body mass index during three years of follow-up , 151 4 , 383-7

Crimmins, N. A.; Martin, L. J. 2007. Polymorphisms in adiponectin receptor genes ADIPOR1 and ADIPOR2 and insulin resistance , 8 5 , 419-423

Crimmins, N. A.; Woo, J. G.; Kaushal, R. D.; Deka, R.; Dolan, L. M.; Martin, L. J. 2007. Adiponectin receptor 1 variants associated with lower insulin resistance in African Americans , 15 8 , 1903-7

Hinton, R. B., Jr.; Martin, L. J.; Tabangin, M. E.; Mazwi, M. L.; Cripe, L. H.; Benson, D. W. 2007. Hypoplastic left heart syndrome is heritable , 50 16 , 1590-5

Martin, L. J.; Ramachandran, V.; Cripe, L. H.; Hinton, R. B.; Andelfinger, G.; Tabangin, M.; Shooner, K.; Keddache, M.; Benson, D. W. 2007. Evidence in favor of linkage to human chromosomal regions 18q, 5q and 13q for bicuspid aortic valve and associated cardiovascular malformations , 121 2 , 275-284

Martin, L.J.; Woo, J.G.; Avery, C.L.; Chen, H-S; North, K. E. 2007. Multiple testing in the genomics era: Findings from GAW15, Group 15. , 121 2 , 275-284

Saunders, C. L.; Chiodini, B. D.; Sham, P.; Lewis, C. M.; Abkevich, V.; Adeyemo, A. A.; de Andrade, M.; Arya, R.; Berenson, G. S.; Blangero, J.; Boehnke, M.; Borecki, I. B.; Chagnon, Y. C.; Chen, W.; Comuzzie, A. G.; Deng, H. W.; Duggirala, R.; Feitosa, M. F.; Froguel, P.; Hanson, R. L.; Hebebrand, J.; Huezo-Dias, P.; Kissebah, A. H.; Li, W.; Luke, A.; Martin, L. J.; Nash, M.; Ohman, M.; Palmer, L. J.; Peltonen, L.; Perola, M.; Price, R. A.; Redline, S.; Srinivasan, S. R.; Stern, M. P.; Stone, S.; Stringham, H.; Turner, S.; Wijmenga, C.; A. Collier D 2007. Meta-analysis of genome-wide linkage studies in BMI and obesity , 15 9 , 2263-75

Tabangin, M.E.; Woo, J. G.; Lui, C.; Nick, T.G.; Martin, L.J. 2007. Comparison of FDR for Genome-wide and Fine Mapping Regions , 1 Suppl 1 , SX

Woo, J. G.; Sun, G.; Haverbusch, M.; Indugula, S.; Martin, L. J.; Broderick, J. P.; Deka, R.; Woo, D. 2007. Quality assessment of buccal versus blood genomic DNA using the Affymetrix 500 K GeneChip , 8 2 , 79

Broeckel, U.; Maresso, K.; Martin, L. J. 2006. Linkage analysis for complex diseases using variance component analysis: SOLAR , 128 2 , 91-100

Martin, L.J. ; Woo, J.G. ; Geraghty, S.R. ; Altaye, M. ; Davidson, B.S. ; Banach, W. ; Dolan, L.M. ; Ruiz-Palacios, G.M. ; Morrow, A.L. 2006. Adiponectin Is Present in Human Milk and Associated with Maternal Factors. , 83 Suppl 1 , 1106-1111

Woo, J. G.; Dolan, L. M.; Deka, R.; Kaushal, R. D.; Shen, Y.; Pal, P.; Daniels, S. R.; Martin, L. J. 2006. Interactions between noncontiguous haplotypes in the adiponectin gene ACDC are associated with plasma adiponectin , 55 2 , 523-9

Avery, C. L.; Martin, L. J.; Williams, J. T.; North, K. E. 2005. Accuracy of haplotype estimation in a region of low linkage disequilibrium , 6 Suppl 1 , S80

Martin, L. J.; Woo, J. G.; Daniels, S. R.; Goodman, E.; Dolan, L. M. 2005. The Relationships of Adiponectin with Insulin and Lipids Are Strengthened with Increasing Adiposity , 90 7 , 4255-4259

Martin, L. J.; Avery, C. L.; Williams, J. T.; North, K. E. 2005. Quantitative trait locus-specific genotype x alcoholism interaction on linkage for evoked electroencephalogram oscillations , 6 Suppl 1 7 , S123

Martin, L.J.; Woo, J. G.; Deka, R; Goodman, E; Daniels, S. R.; Dolan, L. M. 2005. The effect of adiponectin gene variants on insulin resistance is a function of adiposity , 54 Suppl 1 , A282

Molloy, C. A.; Keddache, M.; Martin, L. J. 2005. Evidence for linkage on 21q and 7q in a subset of autism characterized by developmental regression , 18 7 , 1378-82

Mosher, M. J.; Martin, L. J.; Cupples, L. A.; Yang, Q.; Dyer, T. D.; Williams, J. T.; North, K. E. 2005. Genotype-by-sex interaction in the regulation of high-density lipoprotein: the Framingham Heart Study , 77 6 , 773-93

North, K. E.; Miller, M. B.; Coon, H.; Martin, L. J.; Peacock, J. M.; Arnett, D.; Zhang, B.; Province, M.; Oberman, A.; Blangero, J.; Almasy, L.; Ellison, R. C.; Heiss, G. 2005. Evidence for a gene influencing fasting LDL cholesterol and triglyceride levels on chromosome 21q , 179 1 , 119-25

Woo, J. G.; Dolan, L. M.; Daniels, S. R.; Goodman, E.; Martin, L. J. 2005. Adolescent sex differences in adiponectin are conditional on pubertal development and adiposity , 13 12 , 2095-101

Woo, J.G.; Dolan, L.M.; Deka, R; Goodman, E; Daniels, S. R.; Martin, L.J. 2005. Adiponectin gene-adiposity interactions affect high-density lipoprotein (HDL) , 54 Suppl 1 , A282

Cripe, L.; Andelfinger, G.; Martin, L. J.; Shooner, K.; Benson, D. W. 2004. Bicuspid aortic valve is heritable , 44 1 , 138-43

Fairbanks, L. A.; Newman, T. K.; Bailey, J. N.; Jorgensen, M. J.; Breidenthal, S. E.; Ophoff, R. A.; Comuzzie, A. G.; Martin, L. J.; Rogers, J. 2004. Genetic contributions to social impulsivity and aggressiveness in vervet monkeys , 55 6 , 642-7

Martin, L. J.; Cianflone, K.; Zakarian, R.; Nagrani, G.; Almasy, L.; Rainwater, D. L.; Cole, S.; Hixson, J. E.; MacCluer, J. W.; Blangero, J.; Comuzzie, A. G. 2004. Bivariate linkage between acylation-stimulating protein and BMI and high-density lipoproteins , 12 4 , 669-78

Martin, L. J.; Comuzzie, A. G.; Sonnenberg, G. E.; Myklebust, J.; James, R.; Marks, J.; Blangero, J.; Kissebah, A. H. 2004. Major quantitative trait locus for resting heart rate maps to a region on chromosome 4 , 43 5 , 1146-51

Martin, L.J.; Banach, W.; Dolan, L.M.; Davidson, B.S; Geraghty, S.R; Morrow, A.L. 2004. Presence of adiponectin and leptin in human milk , 55 4 Part 2, Suppl S , 36A

Rogers, J.; Martin, L. J.; Comuzzie, A. G.; Mann, J. J.; Manuck, S. B.; Leland, M.; Kaplan, J. R. 2004. Genetics of monoamine metabolites in baboons: overlapping sets of genes influence levels of 5-hydroxyindolacetic acid, 3-hydroxy-4-methoxyphenylglycol, and homovanillic acid , 55 7 , 739-44

Sonnenberg, G. E.; Krakower, G. R.; Martin, L. J.; Olivier, M.; Kwitek, A. E.; Comuzzie, A. G.; Blangero, J.; Kissebah, A. H. 2004. Genetic determinants of obesity-related lipid traits , 45 4 , 610-5

Woo, J. G.; Deka, R.; Dolan, L. M.; Martin, L.J. 2004. Adiponectin variant-11391 interacts with adiposity race to influence adiponectin levels in adolescents. , 159 11 , S24

Woo, J. G.; Dolan, L. M.; Goodman, E; Daniels, S. R.; Martin, L.J. 2004. Gender difference in plasma adiponectin develops during puberty , 53 Suppl 2 , A46

Cole, S. A.; Martin, L. J.; Peebles, K. W.; Leland, M. M.; Rice, K.; VandeBerg, J. L.; Blangero, J.; Comuzzie, A. G. 2003. Genetics of leptin expression in baboons , 27 7 , 778-83

Comuzzie, A. G.; Cole, S. A.; Martin, L.; Carey, K. D.; Mahaney, M. C.; Blangero, J.; VandeBerg, J. L. 2003. The baboon as a nonhuman primate model for the study of the genetics of obesity , 11 1 , 75-80

Dick, E. J., Jr.; Hubbard, G. B.; Martin, L. J.; Leland, M. M. 2003. Record review of baboons with histologically confirmed endometriosis in a large established colony , 32 1 , 39-47

Goldin, L. R.; Camp, N. J.; Keen, K. J.; Martin, L. J.; Moslehi, R.; Ghosh, S.; North, K. E.; Wyszynski, D. F.; Blacker, D. 2003. Analysis of metabolic syndrome phenotypes in Framingham Heart Study families from Genetic Analysis Workshop 13 , 25 Suppl 1 6 , S78-89

Martin, L. J.; Carey, K. D.; Comuzzie, A. G. 2003. Variation in menstrual cycle length and cessation of menstruation in captive raised baboons , 124 8-9 , 865-71

Martin, L. J.; Kissebah, A. H.; Sonnenberg, G. E.; Blangero, J.; Comuzzie, A. G. 2003. Genotype-by-smoking interaction for leptin levels in the Metabolic Risk Complications of Obesity Genes project , 27 3 , 334-40

Martin, L. J.; North, K. E.; Dyer, T.; Blangero, J.; Comuzzie, A. G.; Williams, J. 2003. Phenotypic, genetic, and genome-wide structure in the metabolic syndrome , 4 Suppl 1 11 , S95

North, K. E.; Martin, L. J.; Dyer, T.; Comuzzie, A. G.; Williams, J. T. 2003. HDL cholesterol in females in the Framingham Heart Study is linked to a region of chromosome 2q , 4 Suppl 1 2 , S98

Broeckel, U.; Hengstenberg, C.; Mayer, B.; Holmer, S.; Martin, L. J.; Comuzzie, A. G.; Blangero, J.; Nurnberg, P.; Reis, A.; Riegger, G. A.; Jacob, H. J.; Schunkert, H. 2002. A comprehensive linkage analysis for myocardial infarction and its related risk factors , 30 2 , 210-4

Comuzzie, A.G. ; Martin, L.J.; Bacino, C.; Puyau, M. ; Adolph, A.; Vohra, F. ; Cole, S.A. ; Ellis, K. J.; Butte, N. 2002. Genetic Contribution To Obesity-Related Phenotypes In Hispanic Children: Initial Results From The Viva La Familia Study , 86 9 , 4321-5

Martin, L. J.; Cole, S. A.; Hixson, J. E.; Mahaney, M. C.; Czerwinski, S. A.; Almasy, L.; Blangero, J.; Comuzzie, A. G. 2002. Genotype by smoking interaction for leptin levels in the San Antonio Family Heart Study , 22 2 , 105-15

Martin, L. J.; Comuzzie, A. G.; Dupont, S.; Vionnet, N.; Dina, C.; Gallina, S.; Houari, M.; Blangero, J.; Froguel, P. 2002. A quantitative trait locus influencing type 2 diabetes susceptibility maps to a region on 5q in an extended French family , 51 12 , 3568-72

Martin, L. J.; Mahaney, M. C.; Almasy, L.; MacCluer, J. W.; Blangero, J.; Jaquish, C. E.; Comuzzie, A. G. 2002. Leptin's sexual dimorphism results from genotype by sex interactions mediated by testosterone , 10 1 , 14-21

Martin, L. J.; Mahaney, M. C.; Bronikowski, A. M.; Dee Carey, K.; Dyke, B.; Comuzzie, A. G. 2002. Lifespan in captive baboons is heritable , 123 11 , 1461-7

Martin, L. J.; Mahaney, M. C.; Almasy, L.; Hixson, J. E.; Cole, S. A.; MacCluer, J. W.; Jaquish, C. E.; Blangero, J.; Comuzzie, A. G. 2002. A quantitative trait locus on chromosome 22 for serum leptin levels adjusted for serum testosterone , 10 7 , 602-7

Nakeeb, A.; Comuzzie, A. G.; Martin, L.; Sonnenberg, G. E.; Swartz-Basile, D.; Kissebah, A. H.; Pitt, H. A. 2002. Gallstones: genetics versus environment , 235 6 , 842-9

Comuzzie, A. G.; Funahashi, T.; Sonnenberg, G.; Martin, L. J.; Jacob, H. J.; Black, A. E.; Maas, D.; Takahashi, M.; Kihara, S.; Tanaka, S.; Matsuzawa, Y.; Blangero, J.; Cohen, D.; Kissebah, A. 2001. The genetic basis of plasma variation in adiponectin, a global endophenotype for obesity and the metabolic syndrome , 86 9 , 4321-5

Comuzzie, A. G.; Williams, J. T.; Martin, L. J.; Blangero, J. 2001. Searching for genes underlying normal variation in human adiposity , 79 1 , 57-70

Luke, A.; Guo, X.; Adeyemo, A. A.; Wilks, R.; Forrester, T.; Lowe, W., Jr.; Comuzzie, A. G.; Martin, L. J.; Zhu, X.; Rotimi, C. N.; Cooper, R. S. 2001. Heritability of obesity-related traits among Nigerians, Jamaicans and US black people , 25 7 , 1034-41

Martin, L. J.; Blangero, J.; Rogers, J.; Mahaney, M. C.; Hixson, J. E.; Carey, K. D.; Comuzzie, A. G. 2001. A quantitative trait locus influencing activin-to-estrogen ratio in pedigreed baboons maps to a region homologous to human chromosome 19 , 73 6 , 787-800

Martin, L. J.; Blangero, J.; Rogers, J.; Mahaney, M. C.; Hixson, J. E.; Carey, K. D.; Morin, P. A.; Comuzzie, A. G. 2001. A quantitative trait locus influencing estrogen levels maps to a region homologous to human chromosome 20 , 5 2 , 75-80

Martin, L. J.; Comuzzie, A. G.; North, K. E.; Williams, J. T.; Blangero, J. 2001. The utility of Bayesian model averaging for detecting known oligogenic effects , 21 Suppl 1 12 , S789-93

Rainwater, D. L.; Martin, L. J.; Comuzzie, A. G. 2001. Genetic control of coordinated changes in HDL and LDL size phenotypes , 21 11 , 1829-33

Treuth, M. S.; Butte, N. F.; Ellis, K. J.; Martin, L. J.; Comuzzie, A. G. 2001. Familial resemblance of body composition in prepubertal girls and their biological parents , 74 4 , 529-33

Williams, J. T.; North, K. E.; Martin, L. J.; Comuzzie, A. G.; Goring, H. H.; Blangero, J. 2001. Distribution of lod scores in oligogenic linkage analysis , 21 Suppl 1 10 , S805-10

Kissebah, A. H.; Sonnenberg, G. E.; Myklebust, J.; Goldstein, M.; Broman, K.; James, R. G.; Marks, J. A.; Krakower, G. R.; Jacob, H. J.; Weber, J.; Martin, L.; Blangero, J.; Comuzzie, A. G. 2000. Quantitative trait loci on chromosomes 3 and 17 influence phenotypes of the metabolic syndrome , 97 26 , 14478-83