Skip to main content
Photo of  Susan Waltz, PhD

Susan Waltz, PhD

Research Interests

Understanding the cell intrinsic and extrinsic mechanisms of growth factor and receptor tyrosine kinase signaling in the development and progression of hormonally regulated cancers.

Education/Credentials
  • Doctoral Degree: Boonshoft School of Medicine, Wright State University
  • Bachelor's Degree: Youngstown State University
Contact Information
  • Vontz Center for Molecular Studies
  • 3125 Eden Avenue
  • ML 0521
  • Cincinnati, Ohio 45267-0521
  • Office 513-558-8675
  • Email susan.waltz@uc.edu
  • UC Institute Member Seal

Peer Reviewed Publications

Hunt, Brian G; Wicker, Christina A; Bourn, Jennifer R; Lower, Elyse E; Takiar, Vinita; Waltz, Susan E 2020. MST1R (RON) expression is a novel prognostic biomarker for metastatic progression in breast cancer patients. Breast cancer research and treatment, ,

Pease, Nicholas A; Shephard, Miranda S; Sertorio, Mathieu; Waltz, Susan E; Vinnedge, Lisa M Privette 2020. DEK Expression in Breast Cancer Cells Leads to the Alternative Activation of Tumor Associated Macrophages. Cancers, 12 7,

Sullivan, Camille; Brown, Nicholas E; Vasiliauskas, Juozas; Pathrose, Peterson; Starnes, Sandra L; Waltz, Susan E 2020. Prostate Epithelial RON Signaling Promotes M2 Macrophage Activation to Drive Prostate Tumor Growth and Progression. Molecular cancer research : MCR, ,

Babicky, Michele L; Harper, Megan M; Chakedis, Jeffery; Cazes, Alex; Mose, Evangeline S; Jaquish, Dawn V; French, Randall P; Childers, Betzaira; Alakus, Hakan; Schmid, Michael C; Foubert, Phillippe; Miyamoto, Jaclyn; Holman, Patrick J; Walterscheid, Zakkary J; Tang, Chih-Min; Varki, Nissi; Sicklick, Jason K; Messer, Karen; Varner, Judith A; Waltz, Susan E; Lowy, Andrew M 2019. MST1R kinase accelerates pancreatic cancer progression via effects on both epithelial cells and macrophages. Oncogene, ,

Ge, Chunmin; Vilfranc, Chrystelle L; Che, Lixiao; Pandita, Raj K; Hambarde, Shashank; Andreassen, Paul R; Niu, Liang; Olowokure, Olugbenga; Shah, Shimul; Waltz, Susan E; Zou, Lee; Wang, Jiang; Pandita, Tej K; Du, Chunying 2019. The BRUCE-ATR signaling axis is required for accurate DNA replication and suppression of liver cancer development. Hepatology (Baltimore, Md.), ,

Brown, Nicholas E; Paluch, Andrew M; Nashu, Madison A; Komurov, Kakajan; Waltz, Susan E 2018. Tumor Cell Autonomous RON Receptor Expression Promotes Prostate Cancer Growth Under Conditions of Androgen Deprivation. Neoplasia (New York, N.Y.), 20 9, 917-929

Brown, Nicholas E; Sullivan, Camille; Waltz, Susan E 2018. Therapeutic Considerations for Ron Receptor Expression in Prostate Cancer. EMS cancer science journal, 1 1,

Modur, Vishnu; Singh, Navneet; Mohanty, Vakul; Chung, Eunah; Muhammad, Belal; Choi, Kwangmin; Chen, Xiaoting; Chetal, Kashish; Ratner, Nancy; Salomonis, Nathan; Weirauch, Matthew T; Waltz, Susan; Huang, Gang; Privette-Vinnedge, Lisa; Park, Joo-Seop; Janssen, Edith M; Komurov, Kakajan 2018. Defective transcription elongation in a subset of cancers confers immunotherapy resistance. Nature communications, 9 1, 4410

Andrade, Kelsi; Fornetti, Jaime; Zhao, Ling; Miller, Scott C; Randall, R Lor; Anderson, Neysi; Waltz, Susan E; McHale, Mark; Welm, Alana L 2017. RON kinase: A target for treatment of cancer-induced bone destruction and osteoporosis. Science translational medicine, 9 374,

Hunt, Brian G; Wang, Yuan-Liang; Chen, Min-Shan; Wang, Shao-Chun; Waltz, Susan E 2017. Maternal diethylhexyl phthalate exposure affects adiposity and insulin tolerance in offspring in a PCNA-dependent manner. Environmental research, 159 , 588-594

Ruiz-Torres, Sasha J; Benight, Nancy M; Karns, Rebekah A; Lower, Elyse E; Guan, Jun-Lin; Waltz, Susan E 2017. HGFL-mediated RON signaling supports breast cancer stem cell phenotypes via activation of non-canonical ?-catenin signaling. Oncotarget, 8 35, 58918-58933

Ruiz-Torres, Sasha J; Benight, Nancy M; Karns, Rebekah A; Lower, Elyse E; Guan, Jun-Lin; Waltz, Susan E 2017. HGFL-mediated RON signaling supports breast cancer stem cell phenotypes via activation of non-canonical β-catenin signaling. Oncotarget, 8 35, 58918-58933

Zhou, Zilan; Jafari, Mina; Sriram, Vishnu; Kim, Jinsoo; Lee, Joo-Youp; Ruiz-Torres, Sasha J; Waltz, Susan E 2017. Delayed Sequential Co-Delivery of Gefitinib and Doxorubicin for Targeted Combination Chemotherapy. Molecular pharmaceutics, 14 12, 4551-4559

Zhou, Zilan; Kennell, Carly; Jafari, Mina; Lee, Joo-Youp; Ruiz-Torres, Sasha J; Waltz, Susan E; Lee, Jing-Huei 2017. Sequential Delivery of Erlotinib and Doxorubicin for Enhanced Triple Negative Breast Cancer Treatment Using Polymeric Nanoparticle. International journal of pharmaceutics, ,

Benight, Nancy M; Wagh, Purnima K; Zinser, Glendon M; Peace, Belinda E; Stuart, William D; Vasiliauskas, Juozas; Pathrose, Peterson; Starnes, Sandra L; Waltz, Susan E 2015. HGFL supports mammary tumorigenesis by enhancing tumor cell intrinsic survival and influencing macrophage and T-cell responses. Oncotarget, 6 19, 17445-61

Johnson, Abby L; Zinser, Glendon M; Waltz, Susan E 2015. Vitamin D3-dependent VDR signaling delays ron-mediated breast tumorigenesis through suppression of Beta-catenin activity Oncotarget, 6 18, 16304-20

Stuart, William D; Brown, Nicholas E; Paluch, Andrew M; Waltz, Susan E 2015. Loss of Ron receptor signaling leads to reduced obesity, diabetic phenotypes and hepatic steatosis in response to high fat diet in mice. American journal of physiology. Endocrinology and metabolism, 308 7, E562-72

Gurusamy, Devikala; Ruiz-Torres, Sasha J; Johnson, Abby L; Smith, Dana A; Waltz, Susan E 2014. Hepatocyte growth factor-like protein is a positive regulator of early mammary gland ductal morphogenesis. Mechanisms of development, 133 , 11-22

Johnson, Abby L; Zinser, Glendon M; Waltz, Susan E 2014. Loss of vitamin D receptor signaling from the mammary epithelium or adipose tissue alters pubertal glandular development. American journal of physiology. Endocrinology and metabolism, 307 8, E674-85

Kulkarni, Rishikesh M; Stuart, William D; Gurusamy, Devikala; Waltz, Susan E 2014. Ron receptor signaling is protective against DSS-induced colitis in mice. American journal of physiology. Gastrointestinal and liver physiology, 306 12, G1065-74

Kulkarni, Rishikesh M; Stuart, William D; Waltz, Susan E 2014. Ron receptor-dependent gene regulation of Kupffer cells during endotoxemia. Hepatobiliary & pancreatic diseases international : HBPD INT, 13 3, 281-92

Privette Vinnedge, L M; Benight, N M; Wagh, P K; Pease, N A; Nashu, M A; Serrano-Lopez, J; Adams, A K; Cancelas, J A; Waltz, S E; Wells, S I 2014. The DEK oncogene promotes cellular proliferation through paracrine Wnt signaling in Ron receptor-positive breast cancers. Oncogene, 34 18, 2325-36

Vasiliauskas, Juozas; Nashu, Madison A; Pathrose, Peterson; Starnes, Sandra L; Waltz, Susan E 2014. Hepatocyte growth factor-like protein is required for prostate tumor growth in the TRAMP mouse model. Oncotarget, 5 14, 5547-58

Zhao H., Chen MS, Lo Y-H, Waltz SE, Wang J, Ho P-C, Vasiliauskas J, Plattner R, Wang YL, Wang SC 2014. The RON receptor tyrosine kinase activates c-ABL to promote cell proliferation through tyrosine phosphorylation of PCNA in breast cancer Oncogene, 33 11, 1429-37

Cai, Yuqi; Balli, David; Ustiyan, Vladimir; Fulford, Logan; Hiller, Andrea; Misetic, Vinko; Zhang, Yufang; Paluch, Andrew M; Waltz, Susan E; Kasper, Susan; Kalin, Tanya V 2013. Foxm1 expression in prostate epithelial cells is essential for prostate carcinogenesis. The Journal of biological chemistry, 288 31, 22527-41

Eyob, Henok; Ekiz, Huseyin Atakan; Derose, Yoko S; Waltz, Susan E; Williams, Matthew A; Welm, Alana L 2013. Inhibition of ron kinase blocks conversion of micrometastases to overt metastases by boosting antitumor immunity. Cancer discovery, 3 7, 751-60

Gurusamy, Devikala; Gray, Jerilyn K; Pathrose, Peterson; Kulkarni, Rishikesh M; Finkleman, Fred D; Waltz, Susan E 2013. Myeloid-specific expression of Ron receptor kinase promotes prostate tumor growth. Cancer research, 73 6, 1752-63

Zhao, H; Chen, M-S; Lo, Y-H; Waltz, S E; Wang, J; Ho, P-C; Vasiliauskas, J; Plattner, R; Wang, Y-L; Wang, S-C 2013. The Ron receptor tyrosine kinase activates c-Abl to promote cell proliferation through tyrosine phosphorylation of PCNA in breast cancer. Oncogene, 33 11, 1429-37

Benight, Nancy M; Waltz, Susan E 2012. Ron receptor tyrosine kinase signaling as a therapeutic target. Expert opinion on therapeutic targets, 16 9, 921-31

Gray, Jerilyn K; Paluch, Andrew M; Stuart, William D; Waltz, Susan E 2012. Ron receptor overexpression in the murine prostate induces prostate intraepithelial neoplasia. Cancer letters, 314 1, 92-101

Huitema, Leonie F A; Renn, Jörg; Logister, Ive; Gray, Jerilyn K; Waltz, Susan E; Flik, Gert; Schulte-Merker, Stefan 2012. Macrophage-stimulating protein and calcium homeostasis in zebrafish. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 26 10, 4092-4101

Kulkarni, Rishikesh M; Kutcher, Louis W; Stuart, William D; Carson, Daniel J; Leonis, Mike A; Waltz, Susan E 2012. Ron receptor-dependent gene regulation in a mouse model of endotoxin-induced acute liver failure. Hepatobiliary & pancreatic diseases international : HBPD INT, 11 4, 383-92

Marshall, Aaron M; McClaine, Rebecca J; Gurusamy, Devikala; Gray, Jerilyn K; Lewnard, Kara E; Khan, Sohaib A; Waltz, Susan E 2012. Estrogen receptor alpha deletion enhances the metastatic phenotype of Ron overexpressing mammary tumors in mice. Molecular cancer, 11 , 2

Wagh, Purnima K; Zinser, Glendon M; Gray, Jerilyn K; Shrestha, Archana; Waltz, Susan E 2012. Conditional deletion of ?-catenin in mammary epithelial cells of Ron receptor, Mst1r, overexpressing mice alters mammary tumorigenesis. Endocrinology, 153 6, 2735-46

Nikolaidis, Nikolaos M; Kulkarni, Rishikesh M; Gray, Jerilyn K; Collins, Margaret H; Waltz, Susan E 2011. Ron receptor deficient alveolar myeloid cells exacerbate LPS-induced acute lung injury in the murine lung. Innate immunity, 17 6, 499-507

Privette Vinnedge, L M; McClaine, R; Wagh, P K; Wikenheiser-Brokamp, K A; Waltz, S E; Wells, S I 2011. The human DEK oncogene stimulates ?-catenin signaling, invasion and mammosphere formation in breast cancer. Oncogene, 30 24, 2741-52

Stuart, William D; Kulkarni, Rishikesh M; Gray, Jerilyn K; Vasiliauskas, Juozas; Leonis, Mike A; Waltz, Susan E 2011. Ron receptor regulates Kupffer cell-dependent cytokine production and hepatocyte survival following endotoxin exposure in mice. Hepatology (Baltimore, Md.), 53 5, 1618-28

Thobe, M N; Gray, J K; Gurusamy, D; Paluch, A M; Wagh, P K; Pathrose, P; Lentsch, A B; Waltz, S E 2011. The Ron receptor promotes prostate tumor growth in the TRAMP mouse model. Oncogene, 30 50, 4990-8

Wagh, P K; Gray, J K; Zinser, G M; Vasiliauskas, J; James, L; Monga, S P; Waltz, S E 2011. β-Catenin is required for Ron receptor-induced mammary tumorigenesis. Oncogene, 30 34, 3694-704

Welsh, JoEllen; Zinser, Lindsay N; Mianecki-Morton, Laurel; Martin, Jamie; Waltz, Susan E; James, Howard; Zinser, Glendon M 2011. Age-related changes in the epithelial and stromal compartments of the mammary gland in normocalcemic mice lacking the vitamin D3 receptor. PloS one, 6 1, e16479

Zhao, Huajun; Lo, Yuan-Hung; Ma, Li; Waltz, Susan E; Gray, Jerilyn K; Hung, Mien-Chie; Wang, Shao-Chun 2011. Targeting tyrosine phosphorylation of PCNA inhibits prostate cancer growth. Molecular cancer therapeutics, 10 1, 29-36

Jiang, Pingping; Hu, Qiuping; Ito, Mitsuhiro; Meyer, Sara; Waltz, Susan; Khan, Sohaib; Roeder, Robert G; Zhang, Xiaoting 2010. Key roles for MED1 LxxLL motifs in pubertal mammary gland development and luminal-cell differentiation. Proceedings of the National Academy of Sciences of the United States of America, 107 15, 6765-70

Logan-Collins, Jocelyn; Thomas, Ryan M; Yu, Peter; Jaquish, Dawn; Mose, Evangeline; French, Randall; Stuart, William; McClaine, Rebecca; Aronow, Bruce; Hoffman, Robert M; Waltz, Susan E; Lowy, Andrew M 2010. Silencing of RON receptor signaling promotes apoptosis and gemcitabine sensitivity in pancreatic cancers. Cancer research, 70 3, 1130-40

McClaine, Rebecca J; Marshall, Aaron M; Wagh, Purnima K; Waltz, Susan E 2010. Ron receptor tyrosine kinase activation confers resistance to tamoxifen in breast cancer cell lines. Neoplasia (New York, N.Y.), 12 8, 650-8

Meyer, Sara E; Peace, Belinda E; Bahassi, El Mustapha; Kavanaugh, Gina M; Wagh, Purnima K; Robbins, Susan B; Yin, Moying; Wells, Susanne I; Zinser, Glendon M; Stambrook, Peter J; Waltz, Susan E 2010. Chk2*1100delC Acts in synergy with the Ron receptor tyrosine kinase to accelerate mammary tumorigenesis in mice. Cancer letters, 296 2, 186-93

Nikolaidis, Nikolaos M; Gray, Jerilyn K; Gurusamy, Devikala; Fox, William; Stuart, William D; Huber, Nathan; Waltz, Susan E 2010. Ron receptor tyrosine kinase negatively regulates TNFalpha production in alveolar macrophages by inhibiting NF-kappaB activity and Adam17 production. Shock (Augusta, Ga.), 33 2, 197-204

Thobe, M N; Gurusamy, D; Pathrose, P; Waltz, S E 2010. The Ron receptor tyrosine kinase positively regulates angiogenic chemokine production in prostate cancer cells. Oncogene, 29 2, 214-26

Zhao, Huajun; Ou-Yang, Fu; Chen, I-Fen; Hou, Ming-Feng; Yuan, Shyng-Shiou F; Chang, Hsueh-Ling; Lee, Yi-Chen; Plattner, Rina; Waltz, Susan E; Ho, Shuk-Mei; Sims, Jonathan; Wang, Shao-Chun 2010. Enhanced resistance to tamoxifen by the c-ABL proto-oncogene in breast cancer. Neoplasia (New York, N.Y.), 12 3, 214-23

Meyer, Sara E; Waltz, Susan E; Goss, Kathleen H 2009. The Ron receptor tyrosine kinase is not required for adenoma formation in Apc(Min/+) mice. Molecular carcinogenesis, 48 11, 995-1004

Meyer, Sara E; Zinser, Glendon M; Stuart, William D; Pathrose, Peterson; Waltz, Susan E 2009. The Ron receptor tyrosine kinase negatively regulates mammary gland branching morphogenesis. Developmental biology, 333 1, 173-85

Caldwell, Charles C; Martignoni, Andre; Leonis, Mike A; Ondiveeran, Hari Kumar; Fox-Robichaud, Alison E; Waltz, Susan E 2008. Ron receptor tyrosine kinase-dependent hepatic neutrophil recruitment and survival benefit in a murine model of bacterial peritonitis. Critical care medicine, 36 5, 1585-93

Wagh, Purnima K; Peace, Belinda E; Waltz, Susan E 2008. Met-related receptor tyrosine kinase Ron in tumor growth and metastasis. Advances in cancer research, 100 , 1-33

Chan, E. L.; Peace, B. E.; Toney, K.; Kader, S. A.; Pathrose, P.; Collins, M. H.; Waltz, S. E. 2007. Homozygous K5Cre transgenic mice have wavy hair and accelerated malignant progression in a murine model of skin carcinogenesis Mol Carcinog, 46 1 , 49-59

Chan, Edward L; Peace, Belinda E; Toney, Kenya; Kader, Sarah A; Pathrose, Peterson; Collins, Margaret H; Waltz, Susan E 2007. Homozygous K5Cre transgenic mice have wavy hair and accelerated malignant progression in a murine model of skin carcinogenesis. Molecular carcinogenesis, 46 1, 49-59

Lentsch, A. B.; Pathrose, P.; Kader, S.; Kuboki, S.; Collins, M. H.; Waltz, S. E. 2007. The Ron receptor tyrosine kinase regulates acute lung injury and suppresses nuclear factor kappaB activation Shock, 27 3 , 274-80

Lentsch, Alex B; Pathrose, Peterson; Kader, Sarah; Kuboki, Satoshi; Collins, Margaret H; Waltz, Susan E 2007. The Ron receptor tyrosine kinase regulates acute lung injury and suppresses nuclear factor kappaB activation. Shock (Augusta, Ga.), 27 3, 274-80

Leonis, M. A.; Thobe, M. N.; Waltz, S. E. 2007. Ron-receptor tyrosine kinase in tumorigenesis and metastasis Future Oncol, 3 4 , 441-8

Leonis, Mike A; Thobe, Megan N; Waltz, Susan E 2007. Ron-receptor tyrosine kinase in tumorigenesis and metastasis. Future oncology (London, England), 3 4, 441-8

Thomas, R. M.; Toney, K.; Fenoglio-Preiser, C.; Revelo-Penafiel, M. P.; Hingorani, S. R.; Tuveson, D. A.; Waltz, S. E.; Lowy, A. M. 2007. The RON receptor tyrosine kinase mediates oncogenic phenotypes in pancreatic cancer cells and is increasingly expressed during pancreatic cancer progression Cancer Res, 67 13 , 6075-82

Thomas, Ryan M; Toney, Kenya; Fenoglio-Preiser, Cecilia; Revelo-Penafiel, Monica P; Hingorani, Sunil R; Tuveson, David A; Waltz, Susan E; Lowy, Andrew M 2007. The RON receptor tyrosine kinase mediates oncogenic phenotypes in pancreatic cancer cells and is increasingly expressed during pancreatic cancer progression. Cancer research, 67 13, 6075-82

Wetzel, C. C.; Leonis, M. A.; Dent, A.; Olson, M. A.; Longmeier, A. M.; Ney, P. A.; Boivin, G. P.; Kader, S. A.; Caldwell, C. C.; Degen, S. J.; Waltz, S. E. 2007. Short-form Ron receptor is required for normal IFN-gamma production in concanavalin A-induced acute liver injury Am J Physiol Gastrointest Liver Physiol, 292 1 , G253-61

Wetzel, Cynthia C; Leonis, Mike A; Dent, Arlene; Olson, Meredith A; Longmeier, Angela M; Ney, Paul A; Boivin, Greg P; Kader, Sarah A; Caldwell, Charles C; Degen, Sandra J F; Waltz, Susan E 2007. Short-form Ron receptor is required for normal IFN-gamma production in concanavalin A-induced acute liver injury. American journal of physiology. Gastrointestinal and liver physiology, 292 1, G253-61

Mallakin, A.; Kutcher, L. W.; McDowell, S. A.; Kong, S.; Schuster, R.; Lentsch, A. B.; Aronow, B. J.; Leikauf, G. D.; Waltz, S. E. 2006. Gene expression profiles of Mst1r-deficient mice during nickel-induced acute lung injury Am J Respir Cell Mol Biol, 34 1 , 15-27

Mallakin, Ali; Kutcher, Louis W; McDowell, Susan A; Kong, Sue; Schuster, Rebecca; Lentsch, Alex B; Aronow, Bruce J; Leikauf, George D; Waltz, Susan E 2006. Gene expression profiles of Mst1r-deficient mice during nickel-induced acute lung injury. American journal of respiratory cell and molecular biology, 34 1, 15-27

O'Toole, J. M.; Rabenau, K. E.; Burns, K.; Lu, D.; Mangalampalli, V.; Balderes, P.; Covino, N.; Bassi, R.; Prewett, M.; Gottfredsen, K. J.; Thobe, M. N.; Cheng, Y.; Li, Y.; Hicklin, D. J.; Zhu, Z.; Waltz, S. E.; Hayman, M. J.; Ludwig, D. L.; Pereira, D. S. 2006. Therapeutic implications of a human neutralizing antibody to the macrophage-stimulating protein receptor tyrosine kinase (RON), a c-MET family member Cancer Res, 66 18 , 9162-70

O'Toole, Jennifer M; Rabenau, Karen E; Burns, Kerri; Lu, Dan; Mangalampalli, Venkat; Balderes, Paul; Covino, Nicole; Bassi, Rajiv; Prewett, Marie; Gottfredsen, Kimberly J; Thobe, Megan N; Cheng, Yuan; Li, Yiwen; Hicklin, Daniel J; Zhu, Zhenping; Waltz, Susan E; Hayman, Michael J; Ludwig, Dale L; Pereira, Daniel S 2006. Therapeutic implications of a human neutralizing antibody to the macrophage-stimulating protein receptor tyrosine kinase (RON), a c-MET family member. Cancer research, 66 18, 9162-70

Shen, H.; Schuster, R.; Lu, B.; Waltz, S. E.; Lentsch, A. B. 2006. Critical and opposing roles of the chemokine receptors CXCR2 and CXCR3 in prostate tumor growth Prostate, 66 16 , 1721-8

Shen, H.; Schuster, R.; Stringer, K. F.; Waltz, S. E.; Lentsch, A. B. 2006. The Duffy antigen/receptor for chemokines (DARC) regulates prostate tumor growth FASEB J, 20 1 , 59-64

Shen, Hui; Schuster, Rebecca; Lu, Bao; Waltz, Susan E; Lentsch, Alex B 2006. Critical and opposing roles of the chemokine receptors CXCR2 and CXCR3 in prostate tumor growth. The Prostate, 66 16, 1721-8

Shen, Hui; Schuster, Rebecca; Stringer, Keith F; Waltz, Susan E; Lentsch, Alex B 2006. The Duffy antigen/receptor for chemokines (DARC) regulates prostate tumor growth. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 20 1, 59-64

Zinser, G. M.; Leonis, M. A.; Toney, K.; Pathrose, P.; Thobe, M.; Kader, S. A.; Peace, B. E.; Beauman, S. R.; Collins, M. H.; Waltz, S. E. 2006. Mammary-specific Ron receptor overexpression induces highly metastatic mammary tumors associated with beta-catenin activation Cancer Res, 66 24 , 11967-74

Zinser, Glendon M; Leonis, Mike A; Toney, Kenya; Pathrose, Peterson; Thobe, Megan; Kader, Sarah A; Peace, Belinda E; Beauman, Shirelyn R; Collins, Margaret H; Waltz, Susan E 2006. Mammary-specific Ron receptor overexpression induces highly metastatic mammary tumors associated with beta-catenin activation. Cancer research, 66 24, 11967-74

Chan, E. L.; Peace, B. E.; Collins, M. H.; Toney-Earley, K.; Waltz, S. E. 2005. Ron tyrosine kinase receptor regulates papilloma growth and malignant conversion in a murine model of skin carcinogenesis Oncogene, 24 3 , 479-88

Chan, Edward L; Peace, Belinda E; Collins, Margaret H; Toney-Earley, Kenya; Waltz, Susan E 2005. Ron tyrosine kinase receptor regulates papilloma growth and malignant conversion in a murine model of skin carcinogenesis. Oncogene, 24 3, 479-88

Peace, B. E.; Toney-Earley, K.; Collins, M. H.; Waltz, S. E. 2005. Ron receptor signaling augments mammary tumor formation and metastasis in a murine model of breast cancer Cancer Res, 65 4 , 1285-93

Peace, Belinda E; Toney-Earley, Kenya; Collins, Margaret H; Waltz, Susan E 2005. Ron receptor signaling augments mammary tumor formation and metastasis in a murine model of breast cancer. Cancer research, 65 4, 1285-93

Tsutsui, S.; Noorbakhsh, F.; Sullivan, A.; Henderson, A. J.; Warren, K.; Toney-Earley, K.; Waltz, S. E.; Power, C. 2005. RON-regulated innate immunity is protective in an animal model of multiple sclerosis Ann Neurol, 57 6 , 883-95

Tsutsui, Shigeki; Noorbakhsh, Farshid; Sullivan, Andrea; Henderson, Andrew J; Warren, Kenneth; Toney-Earley, Kenya; Waltz, Susan E; Power, Christopher 2005. RON-regulated innate immunity is protective in an animal model of multiple sclerosis. Annals of neurology, 57 6, 883-95

van den Akker, E.; van Dijk, T.; Parren-van Amelsvoort, M.; Grossmann, K. S.; Schaeper, U.; Toney-Earley, K.; Waltz, S. E.; Lowenberg, B.; von Lindern, M. 2004. Tyrosine kinase receptor RON functions downstream of the erythropoietin receptor to induce expansion of erythroid progenitors Blood, 103 12 , 4457-65

van den Akker, Emile; van Dijk, Thamar; Parren-van Amelsvoort, Martine; Grossmann, Katja S; Schaeper, Ute; Toney-Earley, Kenya; Waltz, Susan E; Löwenberg, Bob; von Lindern, Marieke 2004. Tyrosine kinase receptor RON functions downstream of the erythropoietin receptor to induce expansion of erythroid progenitors. Blood, 103 12, 4457-65

Hess, K. A.; Waltz, S. E.; Chan, E. L.; Degen, S. J. 2003. Receptor tyrosine kinase Ron is expressed in mouse reproductive tissues during embryo implantation and is important in trophoblast cell function Biol Reprod, 68 4 , 1267-75

Hess, K. A.; Waltz, S. E.; Toney-Earley, K.; Degen, S. J. 2003. The receptor tyrosine kinase Ron is expressed in the mouse ovary and regulates inducible nitric oxide synthase levels and ovulation Fertil Steril, 80 Suppl 2 2 , 747-54

Hess, Karla Ann; Waltz, Susan E; Chan, Edward L; Degen, Sandra J F 2003. Receptor tyrosine kinase Ron is expressed in mouse reproductive tissues during embryo implantation and is important in trophoblast cell function. Biology of reproduction, 68 4, 1267-75

Hess, Karla Ann; Waltz, Susan E; Toney-Earley, Kenya; Degen, Sandra J F 2003. The receptor tyrosine kinase Ron is expressed in the mouse ovary and regulates inducible nitric oxide synthase levels and ovulation. Fertility and sterility, 80 Suppl 2 , 747-54

Peace, B. E.; Hill, K. J.; Degen, S. J.; Waltz, S. E. 2003. Cross-talk between the receptor tyrosine kinases Ron and epidermal growth factor receptor Exp Cell Res, 289 2 , 317-25

Peace, Belinda E; Hill, Kara J; Degen, Sandra J F; Waltz, Susan E 2003. Cross-talk between the receptor tyrosine kinases Ron and epidermal growth factor receptor. Experimental cell research, 289 2, 317-25

Wetzel, C. C.; Degen, S. J.; Waltz, S. E. 2003. Cis-acting elements in the hepatocyte growth factor-like protein gene regulate kidney and liver-specific expression in mice DNA Cell Biol, 22 5 , 293-301

Wetzel, Cynthia C; Degen, Sandra J F; Waltz, Susan E 2003. Cis-acting elements in the hepatocyte growth factor-like protein gene regulate kidney and liver-specific expression in mice. DNA and cell biology, 22 5, 293-301

Leonis, M. A.; Toney-Earley, K.; Degen, S. J.; Waltz, S. E. 2002. Deletion of the Ron receptor tyrosine kinase domain in mice provides protection from endotoxin-induced acute liver failure Hepatology, 36 5 , 1053-60

Leonis, Mike A; Toney-Earley, Kenya; Degen, Sandra J F; Waltz, Susan E 2002. Deletion of the Ron receptor tyrosine kinase domain in mice provides protection from endotoxin-induced acute liver failure. Hepatology (Baltimore, Md.), 36 5, 1053-60

McDowell, S. A.; Mallakin, A.; Bachurski, C. J.; Toney-Earley, K.; Prows, D. R.; Bruno, T.; Kaestner, K. H.; Witte, D. P.; Melin-Aldana, H.; Degen, S. J.; Leikauf, G. D.; Waltz, S. E. 2002. The role of the receptor tyrosine kinase Ron in nickel-induced acute lung injury Am J Respir Cell Mol Biol, 26 1 , 99-104

McDowell, Susan A; Mallakin, Ali; Bachurski, Cindy J; Toney-Earley, Kenya; Prows, Daniel R; Bruno, Theresa; Kaestner, Klaus H; Witte, David P; Melin-Aldana, Hector; Degen, Sandra J F; Leikauf, George D; Waltz, Susan E 2002. The role of the receptor tyrosine kinase Ron in nickel-induced acute lung injury. American journal of respiratory cell and molecular biology, 26 1, 99-104

Peace, B E; Hughes, M J; Degen, S J; Waltz, S E 2001. Point mutations and overexpression of Ron induce transformation, tumor formation, and metastasis. Oncogene, 20 43, 6142-51

Peace, B. E.; Hughes, M. J.; Degen, S. J.; Waltz, S. E. 2001. Point mutations and overexpression of Ron induce transformation, tumor formation, and metastasis Oncogene, 20 43 , 6142-51

Waltz, S E; Eaton, L; Toney-Earley, K; Hess, K A; Peace, B E; Ihlendorf, J R; Wang, M H; Kaestner, K H; Degen, S J 2001. Ron-mediated cytoplasmic signaling is dispensable for viability but is required to limit inflammatory responses. The Journal of clinical investigation, 108 4, 567-76

Waltz, S. E.; Eaton, L.; Toney-Earley, K.; Hess, K. A.; Peace, B. E.; Ihlendorf, J. R.; Wang, M. H.; Kaestner, K. H.; Degen, S. J. 2001. Ron-mediated cytoplasmic signaling is dispensable for viability but is required to limit inflammatory responses J Clin Invest, 108 4 , 567-76

Waltz, S.; Stephani, U. 2000. Inheritance of photosensitivity Neuropediatrics, 31 2 , 82-5

Muraoka, R S; Sun, W Y; Colbert, M C; Waltz, S E; Witte, D P; Degen, J L; Friezner Degen, S J 1999. The Ron/STK receptor tyrosine kinase is essential for peri-implantation development in the mouse. The Journal of clinical investigation, 103 9, 1277-85

Muraoka, R S; Waltz, S E; Degen, S J 1999. Expression of hepatocyte growth factor-like protein is repressed by retinoic acid and enhanced by cyclic adenosine 3',5'-monophosphate response element-binding protein (CREB)-binding protein (CBP). Endocrinology, 140 1, 187-96

Muraoka, R. S.; Sun, W. Y.; Colbert, M. C.; Waltz, S. E.; Witte, D. P.; Degen, J. L.; Friezner Degen, S. J. 1999. The Ron/STK receptor tyrosine kinase is essential for peri-implantation development in the mouse J Clin Invest, 103 9 , 1277-85

Muraoka, R. S.; Waltz, S. E.; Degen, S. J. 1999. Expression of hepatocyte growth factor-like protein is repressed by retinoic acid and enhanced by cyclic adenosine 3',5'-monophosphate response element-binding protein (CREB)-binding protein (CBP) Endocrinology, 140 1 , 187-96

Waltz, S.; Pohlmann-Eden, B. 1999. [Anticonvulsant drug therapy in children and adults. Practical guide for single and multiple dosage] Fortschr Neurol Psychiatr, 67 3 , 122-30

Degen, S J; McDowell, S A; Waltz, S E; Gould, F; Stuart, L A; Carritt, B 1998. Structure of the human D1F15S1A locus: a chromosome 1 locus with 97% identity to the chromosome 3 gene coding for hepatocyte growth factor-like protein. DNA sequence : the journal of DNA sequencing and mapping, 8 6, 409-13

Degen, S. J.; McDowell, S. A.; Waltz, S. E.; Gould, F.; Stuart, L. A.; Carritt, B. 1998. Structure of the human D1F15S1A locus: a chromosome 1 locus with 97% identity to the chromosome 3 gene coding for hepatocyte growth factor-like protein DNA Seq, 8 6 , 409-13

Trivedi, A.; Waltz, S. E.; Kamath, S.; Leffak, M. 1998. Multiple initiations in the c-myc replication origin independent of chromosomal location DNA Cell Biol, 17 10 , 885-96

Trivedi, A; Waltz, S E; Kamath, S; Leffak, M 1998. Multiple initiations in the c-myc replication origin independent of chromosomal location. DNA and cell biology, 17 10, 885-96

Waltz, S E; Toms, C L; McDowell, S A; Clay, L A; Muraoka, R S; Air, E L; Sun, W Y; Thomas, M B; Degen, S J 1998. Characterization of the mouse Ron/Stk receptor tyrosine kinase gene. Oncogene, 16 1, 27-42

Waltz, S. E.; Toms, C. L.; McDowell, S. A.; Clay, L. A.; Muraoka, R. S.; Air, E. L.; Sun, W. Y.; Thomas, M. B.; Degen, S. J. 1998. Characterization of the mouse Ron/Stk receptor tyrosine kinase gene Oncogene, 16 1 , 27-42

Waltz, S E; McDowell, S A; Muraoka, R S; Air, E L; Flick, L M; Chen, Y Q; Wang, M H; Degen, S J 1997. Functional characterization of domains contained in hepatocyte growth factor-like protein. The Journal of biological chemistry, 272 48, 30526-37

Waltz, S. E.; McDowell, S. A.; Muraoka, R. S.; Air, E. L.; Flick, L. M.; Chen, Y. Q.; Wang, M. H.; Degen, S. J. 1997. Functional characterization of domains contained in hepatocyte growth factor-like protein J Biol Chem, 272 48 , 30526-37

Waltz, S E; Gould, F K; Air, E L; McDowell, S A; Degen, S J 1996. Hepatocyte nuclear factor-4 is responsible for the liver-specific expression of the gene coding for hepatocyte growth factor-like protein. The Journal of biological chemistry, 271 15, 9024-32

Waltz, S E; Trivedi, A A; Leffak, M 1996. DNA replication initiates non-randomly at multiple sites near the c-myc gene in HeLa cells. Nucleic acids research, 24 10, 1887-94

Waltz, S. E.; Trivedi, A. A.; Leffak, M. 1996. DNA replication initiates non-randomly at multiple sites near the c-myc gene in HeLa cells Nucleic Acids Res, 24 10 , 1887-94

Waltz, S. E.; Gould, F. K.; Air, E. L.; McDowell, S. A.; Degen, S. J. 1996. Hepatocyte nuclear factor-4 is responsible for the liver-specific expression of the gene coding for hepatocyte growth factor-like protein J Biol Chem, 271 15 , 9024-32

McWhinney, C; Waltz, S E; Leffak, M 1995. Cis-acting effects of sequences within 2.4-kb upstream of the human c-myc gene on autonomous plasmid replication in HeLa cells. DNA and cell biology, 14 7, 565-79

Ruiz-Torres S.;Benight N.;Karns R.;Lower E.;Guan J.;Waltz S. 01-01-2017. HGFL-mediated RON signaling supports breast cancer stem cell phenotypes via activation of non-canoni Oncotarget, 8 35, 58918-58933

McClaine R.;Marshall A.;Wagh P.;Waltz S. 01-01-2010. Ron receptor tyrosine kinase activation confers resistance to tamoxifen in breast cancer cell lines Neoplasia, 12 8, 650-658

Zhao H.;Ou-Yang F.;Chen I.F.;Hou M.F.;Yuan S.S.F.;Chang H.L.;Lee Y.C.;Plattner R.;Waltz S.E.;Ho S.M.;Sims J.;Wang S.C. 01-01-2010. Enhanced resistance to tamoxifen by the c-ABL proto-oncogene in breast cancer Neoplasia, 12 3, 214-223