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Photo of  Dani S. Zander, MD

Dani S. Zander, MD

Department Chair

MacKenzie Endowed Chair & Professor

Pathology & Laboratory Medicine | College of Medicine

  • Fellow, Executive Leadership in Academic Medicine Program: Drexel University College of Medicine
  • Residency: University of Florida College of Medicine (Anatomic and Clinical Pathology)
  • Internship (Anatomic and Clinical Pathology): New York Hospital
  • Doctor of Medicine: University of Florida
  • Bachelor of Arts: New York University (Chemistry)
Board Certifications & Licenses

American Board of Pathology (Anatomic and Clinical Pathology) (Certification Date: 1991-11-20)
American Board of Pathology (Cytopathology) (Certification Date: 1997-07-15)


Pathology-Anatomic and Clinical

Contact Information
Research Interests

Lung pathology
Lung cancer

Clinical Interests


Peer Reviewed Publications

Shaw, Brian; Borchers, Michael; Zander, Dani; Gupta, Nishant 2020. Pulmonary Langerhans Cell Histiocytosis. Seminars in respiratory and critical care medicine, 41 2, 269-279

Howell, Lydia Pleotis; Markwood, Priscilla S; Zander, Dani S 2019. The Association of Pathology Chairs' Pathology Leadership Academy: Experience From the First 2 Years. Academic pathology, 6 , 2374289519826309

Lorenz, Robin G; Karcher, Donald S; Gautreaux, Michael D; Limson, Melvin; Zander, Dani S 2018. The Pathology Workforce and Clinical Licensure: The Role of the PhD Clinical Laboratorian in the United States. Academic pathology, 5 , 2374289518775948

Balestra, Rick; Selvaraju, Akilan; Benzaquen, Sadia; Zander, Dani S 2017. Pneumonic-type mucinous lung adenocarcinoma diagnosed by transbronchial cryobiopsy. Respirology case reports, 5 3, e00222

Gupta, N; Wikenheiser-Brokamp, K; Zander, D; Balestra, R; Selvaraju, A; Niehaus, K; Benzaquen, S 2017. Successful diagnosis of lymphangioleiomyomatosis with transbronchial lung cryobiopsy. Lymphology, 50 3, 154-157

Liu, Yong-Jun; Kessler, Meghan; Zander, Dani S; Karamchandani, Dipti M 2016. Trends in extramural consultation: comparison between subspecialized and general surgical pathology service models. Annals of diagnostic pathology, 24 , 20-4

Lokhandwala, Parvez M; Abendroth, Catherine S; Wang, Ming; Mani, Haresh; Williams, Nicole C; Walls, Michelle; Zander, Dani S 2016. Assessment of cytotechnologist-cytopathologist interpretative agreement using the Bethesda system for reporting thyroid cytopathology. Diagnostic cytopathology, 44 2, 113-8

Yang, Xuebin; Liu, Yongjun; Mani, Haresh; Olson, Jeffrey; Clawson, Gary; Caruso, Carla; Bruggeman, Richard; Varlotto, John M; Zander, Dani S; Rassaei, Negar 2016. Biologic Evaluation of Diabetes and Local Recurrence in Non-Small Cell Lung Cancer. Pathology oncology research : POR, ,

Mani, Haresh; Zander, Dani S 2014. Response. Chest, 145 6, 1442

Varlotto, John M; Medford-Davis, Laura N; Recht, Abram; Flickinger, John; Yao, Nengliang; Hess, Clayton; Reed, Michael F; Toth, Jennifer; Zander, Dani S; DeCamp, Malcolm M 2013. Identification of stage I non-small cell lung cancer patients at high risk for local recurrence following sublobar resection. Chest, 143 5, 1365-77

Zander, Dani S 2013. Volumetric optical frequency domain imaging: building a new lexicon. Chest, 143 1, 10-2

Mani, Haresh; Zander, Dani S 2012. Immunohistochemistry: applications to the evaluation of lung and pleural neoplasms: part 2. Chest, 142 5, 1324-33

Mani, Haresh; Zander, Dani S 2012. Immunohistochemistry: applications to the evaluation of lung and pleural neoplasms: part 1. Chest, 142 5, 1316-23

Mukhopadhyay, Sanjay; Farver, Carol F; Vaszar, Laszlo T; Dempsey, Owen J; Popper, Helmut H; Mani, Haresh; Capelozzi, Vera L; Fukuoka, Junya; Kerr, Keith M; Zeren, E Handan; Iyer, Venkateswaran K; Tanaka, Tomonori; Narde, Ivy; Nomikos, Angheliki; Gumurdulu, Derya; Arava, Sudheer; Zander, Dani S; Tazelaar, Henry D 2012. Causes of pulmonary granulomas: a retrospective study of 500 cases from seven countries. Journal of clinical pathology, 65 1, 51-7

Qi, Ji; Rice, Shawn J; Salzberg, Anna C; Runkle, E Aaron; Liao, Jason; Zander, Dani S; Mu, David 2012. MiR-365 regulates lung cancer and developmental gene thyroid transcription factor 1. Cell cycle (Georgetown, Tex.), 11 1, 177-86

Anani, Waseem; Bruggeman, Richard; Zander, Dani S 2011. ?-catenin expression in benign and malignant pleural disorders. International journal of clinical and experimental pathology, 4 8, 742-7

Varlotto, John M; Medford-Davis, Laura Nyshel; Recht, Abram; Flickinger, John C; Schaefer, Eric; Zander, Dani S; DeCamp, Malcolm M 2011. Should large cell neuroendocrine lung carcinoma be classified and treated as a small cell lung cancer or with other large cell carcinomas? Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 6 6, 1050-8

Weiss, Ronald L; McKenna, Barbara J; Lord-Toof, Melissa; Thompson, Nancie Noie 2011. A consensus curriculum for laboratory management training for pathology residents. American journal of clinical pathology, 136 5, 671-8

Liang, John J; Zhu, Shaobo; Bruggeman, Richard; Zaino, Richard J; Evans, Douglas B; Fleming, Jason B; Gomez, Henry F; Zander, Dani S; Wang, Huamin 2010. High levels of expression of human stromal cell-derived factor-1 are associated with worse prognosis in patients with stage II pancreatic ductal adenocarcinoma. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 19 10, 2598-604

Todd, William U; Drabick, Joseph J; Benninghoff, Michael G; Frauenhoffer, Elizabeth E; Zander, Dani S 2010. Pulmonary crystal-storing histiocytosis diagnosed by computed tomography-guided fine-needle aspiration. Diagnostic cytopathology, 38 4, 274-8

Zander, Dani S 2010. Primary vs metastatic pulmonary adenocarcinoma: toward a fuller understanding of truth. Chest, 137 1, 3-4

Mercer, Robyn R; Lucas, Natalie C; Simmons, Alicia N; Zander, Dani S; Tsongalis, Gregory J; Funkhouser, William K; Coleman, William B 2009. Molecular discrimination of multiple primary versus metastatic squamous cell cancers of the head/neck and lung. Experimental and molecular pathology, 86 1, 1-9

Chiosea, Simion; Krasinskas, Alyssa; Cagle, Philip T; Mitchell, Kisha A; Zander, Dani S; Dacic, Sanja 2008. Diagnostic importance of 9p21 homozygous deletion in malignant mesotheliomas. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 21 6, 742-7

Patel, Miten; Lu, Li; Zander, Dani S; Sreerama, Lakshmaiah; Coco, Dominique; Moreb, Jan S 2008. ALDH1A1 and ALDH3A1 expression in lung cancers: correlation with histologic type and potential precursors. Lung cancer (Amsterdam, Netherlands), 59 3, 340-9

Tan, Dongfeng; Zander, Dani S 2008. Immunohistochemistry for assessment of pulmonary and pleural neoplasms: a review and update. International journal of clinical and experimental pathology, 1 1, 19-31

Allen, Timothy C; Granville, Laura A; Cagle, Philip T; Haque, Abida; Zander, Dani S; Barrios, Roberto 2007. Expression of glutathione S-transferase pi and glutathione synthase correlates with survival in early stage non-small cell carcinomas of the lung. Human pathology, 38 2, 220-7

Kwon, Kun Y; Ro, Jae Y; Singhal, Nicholas; Killen, Deanna E; Sienko, Anna; Allen, Timothy C; Zander, Dani S; Barrios, Roberto; Haque, Abida; Cagle, Philip T 2007. MUC4 expression in non-small cell lung carcinomas: relationship to tumor histology and patient survival. Archives of pathology & laboratory medicine, 131 4, 593-8

Zander, Dani S 2007. Transbronchial fine-needle aspiration, epidermal growth factor receptor mutations, and the scorpion's touch. Chest, 131 6, 1619-20

Andino, Lizmarie; Cagle, Philip T; Murer, Bruno; Lu, Li; Popper, Helmut H; Galateau-Salle, Francoise; Sienko, Anna E; Barrios, Roberto; Zander, Dani S 2006. Pleuropulmonary desmoid tumors: immunohistochemical comparison with solitary fibrous tumors and assessment of beta-catenin and cyclin D1 expression. Archives of pathology & laboratory medicine, 130 10, 1503-9

Butnor, Kelly J; Nicholson, Andrew G; Allred, D Craig; Zander, Dani S; Henderson, Douglas W; Barrios, Roberto; Haque, Abida K; Allen, Timothy C; Killen, Deanna E; Cagle, Philip T 2006. Expression of renal cell carcinoma-associated markers erythropoietin, CD10, and renal cell carcinoma marker in diffuse malignant mesothelioma and metastatic renal cell carcinoma. Archives of pathology & laboratory medicine, 130 6, 823-7

Kalhor, Neda; Zander, Dani S; Liu, Jing 2006. TTF-1 and p63 for distinguishing pulmonary small-cell carcinoma from poorly differentiated squamous cell carcinoma in previously pap-stained cytologic material. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 19 8, 1117-23

Zander, Dani S 2006. Bronchoscopic cytology: Expanding the menu. Chest, 130 3, 634-5

Zander, Dani S; Cogle, Christopher R; Theise, Neil D; Crawford, James M 2006. Donor-derived type II pneumocytes are rare in the lungs of allogeneic hematopoietic cell transplant recipients. Annals of clinical and laboratory science, 36 1, 47-52

Allen, Timothy Craig; Bag, Remzi; Zander, Dani S; Cagle, Philip T 2005. Cytomegalovirus infection masquerading as carcinoma in a lung transplant patient. Archives of pathology & laboratory medicine, 129 1, e1-3

Granville, Laura; Laga, Alvaro C; Allen, Timothy Craig; Dishop, Megan; Roggli, Victor L; Churg, Andrew; Zander, Dani S; Cagle, Philip T 2005. Review and update of uncommon primary pleural tumors: a practical approach to diagnosis. Archives of pathology & laboratory medicine, 129 11, 1428-43

Laga, Alvaro C; Zander, Dani S; Cagle, Philip T 2005. Prognostic significance of cyclooxygenase 2 expression in 259 cases of non-small cell lung cancer. Archives of pathology & laboratory medicine, 129 9, 1113-7

Sienko, Anna; Allen, Timothy Craig; Zander, Dani S; Cagle, Philip T 2005. Frozen section of lung specimens. Archives of pathology & laboratory medicine, 129 12, 1602-9

Stevens, Tobey A; Brown, Jubilee; Zander, Dani S; Bevers, Michael W; Gershenson, David M; Ramondetta, Lois M 2005. Adult granulosa cell tumors of the ovary in two first-degree relatives. Gynecologic oncology, 98 3, 502-5

Zander, Dani S 2005. Allergic bronchopulmonary aspergillosis: an overview. Archives of pathology & laboratory medicine, 129 7, 924-8

Zander, Dani S; Baz, Maher A; Cogle, Christopher R; Visner, Gary A; Theise, Neil D; Crawford, James M 2005. Bone marrow-derived stem-cell repopulation contributes minimally to the Type II pneumocyte pool in transplanted human lungs. Transplantation, 80 2, 206-12

Zhang, Hong; Liu, Jing; Cagle, Philip T; Allen, Timothy C; Laga, Alvaro C; Zander, Dani S 2005. Distinction of pulmonary small cell carcinoma from poorly differentiated squamous cell carcinoma: an immunohistochemical approach. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 18 1, 111-8

Zhou, Hailan; Latham, Christopher W; Zander, Dani S; Margolin, Solomon B; Visner, Gary A 2005. Pirfenidone inhibits obliterative airway disease in mouse tracheal allografts. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 24 10, 1577-85

Bonnell, Mark R; Visner, Gary A; Zander, Dani S; Mandalapu, Subbarao; Kazemfar, Kristy; Spears, Linnea; Beaver, Thomas M 2004. Heme-oxygenase-1 expression correlates with severity of acute cellular rejection in lung transplantation. Journal of the American College of Surgeons, 198 6, 945-52

Cogle, Christopher R; Yachnis, Anthony T; Laywell, Eric D; Zander, Dani S; Wingard, John R; Steindler, Dennis A; Scott, Edward W 2004. Bone marrow transdifferentiation in brain after transplantation: a retrospective study. Lancet (London, England), 363 9419, 1432-7

Visner, Gary A; Faro, Albert; Zander, Dani S 2004. Role of transbronchial biopsies in pediatric lung diseases. Chest, 126 1, 273-80

Zander, Dani S 2004. Core roll preparations and the pathologist as consultant. Chest, 126 3, 664-6

Zander, Dani S 2004. Idiopathic interstitial pneumonias and the concept of the trump card. Chest, 125 2, 359-60

Zhou, Hailan; Lu, Fuhua; Latham, Christopher; Zander, Dani S; Visner, Gary A 2004. Heme oxygenase-1 expression in human lungs with cystic fibrosis and cytoprotective effects against Pseudomonas aeruginosa in vitro. American journal of respiratory and critical care medicine, 170 6, 633-40

Dennery, Phyllis A; Visner, Gary; Weng, Y i-Hao; Nguyen, Xuandai; Lu, Fuhua; Zander, Dani; Yang, Guang 2003. Resistance to hyperoxia with heme oxygenase-1 disruption: role of iron. Free radical biology & medicine, 34 1, 124-33

Foster, Runi A; Zander, Dani S; Mergo, Patricia J; Valentine, John F 2003. Mesalamine-related lung disease: clinical, radiographic, and pathologic manifestations. Inflammatory bowel diseases, 9 5, 308-15

Visner, Gary A; Lu, Fuhua; Zhou, Hailan; Latham, Christopher; Agarwal, Anupam; Zander, Dani S 2003. Graft protective effects of heme oxygenase 1 in mouse tracheal transplant-related obliterative bronchiolitis. Transplantation, 76 4, 650-6

Iczkowski, Kenneth A; Katz, Giora; Zander, Dani S; Clapp, William L 2002. Malignant mesothelioma of tunica vaginalis testis: a fatal case with liver metastasis. The Journal of urology, 167 2 Pt 1, 645-6

Lu, Fuhua; Zander, Dani S; Visner, Gary A 2002. Increased expression of heme oxygenase-1 in human lung transplantation. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 21 10, 1120-6

Look, D C; Walter, M J; Williamson, M R; Pang, L; You, Y; Sreshta, J N; Johnson, J E; Zander, D S; Brody, S L 2001. Effects of paramyxoviral infection on airway epithelial cell Foxj1 expression, ciliogenesis, and mucociliary function. The American journal of pathology, 159 6, 2055-69

Palmer, S M; Baz, M A; Sanders, L; Miralles, A P; Lawrence, C M; Rea, J B; Zander, D S; Edwards, L J; Staples, E D; Tapson, V F; Davis, R D 2001. Results of a randomized, prospective, multicenter trial of mycophenolate mofetil versus azathioprine in the prevention of acute lung allograft rejection. Transplantation, 71 12, 1772-6

Zander, D S; Baz, M A; Visner, G A; Staples, E D; Donnelly, W H; Faro, A; Scornik, J C 2001. Analysis of early deaths after isolated lung transplantation. Chest, 120 1, 225-32

Bavry, A A; Li, D; Zander, D S; Phillips, M I; Mehta, J L 2000. Inhibition of arterial thrombogenesis by quinapril but not losartan. Journal of cardiovascular pharmacology and therapeutics, 5 2, 121-7

Mainwaring, M G; Poor, C; Zander, D S; Harman, E 2000. Complete remission of pulmonary spindle cell carcinoma after treatment with oral germanium sesquioxide. Chest, 117 2, 591-3

Zander, D S; Cicale, M J; Mergo, P 2000. Durable cure of mucormycosis involving allograft and native lungs. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 19 6, 615-8

Kinsely, B L; Mastey, L A; Mergo, P J; Voytovich, M C; Zander, D; Almasri, N M; Collins, J; Kuhlman, J E 1999. Pulmonary mucosa-associated lymphoid tissue lymphoma: CT and pathologic findings. AJR. American journal of roentgenology, 172 5, 1321-6

Li, D; Weng, S; Yang, B; Zander, D S; Saldeen, T; Nichols, W W; Khan, S; Mehta, J L 1999. Inhibition of arterial thrombus formation by ApoA1 Milano. Arteriosclerosis, thrombosis, and vascular biology, 19 2, 378-83

Scornik, J C; Zander, D S; Baz, M A; Donnelly, W H; Staples, E D 1999. Susceptibility of lung transplants to preformed donor-specific HLA antibodies as detected by flow cytometry. Transplantation, 68 10, 1542-6

Yang, B C; Zander, D S; Mehta, J L 1999. Hypoxia-reoxygenation-induced apoptosis in cultured adult rat myocytes and the protective effect of platelets and transforming growth factor-beta(1). The Journal of pharmacology and experimental therapeutics, 291 2, 733-8

Zander, D S; Baz, M A; Massey, J K 1999. Patterns and significance of CD44 expression in lung allografts. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 18 7, 646-53

Collins, J; Müller, N L; Leung, A N; McGuinness, G; Mergo, P J; Flint, J D; Warner, T F; Poirier, C; Theodore, J; Zander, D; Yee, H T 1998. Epstein-Barr-virus-associated lymphoproliferative disease of the lung: CT and histologic findings. Radiology, 208 3, 749-59

Kostense, S; Sun, W H; Cottey, R; Taylor, S F; Harmeling, S; Zander, D; Small, P A; Bender, B S 1998. Interleukin 12 administration enhances Th1 activity but delays recovery from influenza A virus infection in mice. Antiviral research, 38 2, 117-30

Zaer, F S; Braylan, R C; Zander, D S; Iturraspe, J A; Almasri, N M 1998. Multiparametric flow cytometry in the diagnosis and characterization of low-grade pulmonary mucosa-associated lymphoid tissue lymphomas. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 11 6, 525-32

Engles, R E; Huber, T S; Zander, D S; Hess, P J; Welborn, M B; Moldawer, L L; Seeger, J M 1997. Exogenous human recombinant interleukin-10 attenuates hindlimb ischemia-reperfusion injury. The Journal of surgical research, 69 2, 425-8

Taylor, S F; Cottey, R J; Zander, D S; Bender, B S 1997. Influenza infection of beta 2-microglobulin-deficient (beta 2m-/-) mice reveals a loss of CD4+ T cell functions with aging. Journal of immunology (Baltimore, Md. : 1950), 159 7, 3453-9

Bender, B S; Taylor, S F; Zander, D S; Cottey, R 1995. Pulmonary immune response of young and aged mice after influenza challenge. The Journal of laboratory and clinical medicine, 126 2, 169-77

Gonzalez-Rothi, R J; Zander, D S; Ros, P R 1995. Fluoxetine hydrochloride (Prozac)-induced pulmonary disease. Chest, 107 6, 1763-5

Medina, R; Faecher, R S; Stafford, D S; Zander, D S; Baughman, R A 1994. Systemic mastocytosis involving the mandible. Oral surgery, oral medicine, and oral pathology, 78 1, 28-35

Visner, G A; Staples, E D; Chesrown, S E; Block, E R; Zander, D S; Nick, H S 1994. Isolation and maintenance of human pulmonary artery endothelial cells in culture isolated from transplant donors. The American journal of physiology, 267 4 Pt 1, L406-13

Zander, D S; Iturraspe, J A; Everett, E T; Massey, J K; Braylan, R C 1994. Flow cytometry. In vitro assessment of its potential application for diagnosis and classification of lymphoid processes in cytologic preparations from fine-needle aspirates. American journal of clinical pathology, 101 5, 577-86

Haught, W H; Steinbach, J; Zander, D S; Wingo, C S 1993. Case report: bacillary angiomatosis with massive visceral lymphadenopathy. The American journal of the medical sciences, 306 4, 236-40

Oblon, D J; Parsons, J T; Zander, D S; Wajsman, Z 1993. Bladder preservation and durable complete remission of small cell carcinoma of the bladder with systemic chemotherapy and adjuvant radiation therapy. Cancer, 71 8, 2581-4

Steinbach, B G; Steinbach, J J; Zander, D S 1993. Bilateral breast masses in a man. Military medicine, 158 5, 356-7