Basic Science Research

The UC Department of Neurology and Rehabilitation Medicine is not only recognized for providing world-class subspecialty care, but also is considered a leader in translating research from the laboratory to the bedside and back again. Our researchers have played a role in lifesaving medical breakthroughs and continually seek improved treatments and therapies for patients.

The department’s clinical and basic multi-disciplinary research program has been consistently ranked in the top 10 of all departments of neurology in the United States and in the top five of public universities.

Our basic science researchers, whose laboratories are located in exceptional space in the CARE/Crawley Building and The Vontz Center for Molecular Studies, work closely with our physician-researchers to discover cures and develop new treatment approaches.

Our research has revolutionized the treatment and understanding of neurologic diseases. Our translational research program in the laboratory consists of funded scientists in cerebrovascular disease, concussion, growth factor therapies for and effects of stress in neurodegenerative disease, neuroimaging, genetics, neuro-oncology, and novel animal models of neurologic disease.

Basic Science Research Team

Debanjan Bhattacharya, PhD
Instructor of Neurology & Rehabilitation Medicine
Bhattacharya is a scientist with a long-standing research interest in pediatric and adult brain tumors. He has particular interest in application of various murine models to study molecular neuro-oncology and drug efficacy. Bhattacharya works closely with Neurology department colleagues Sengupta and Pomeranz Krummel. He is a member of the Neuro-Oncology laboratory.

LinkedIn: Debanjan Bhattacharya LinkedIn

Joe Clark, PhD
Professor of Neurology
Clark is interested in the vascular mechanisms of cerebral vascular diseases such as stroke, brain hemorrhage and cognitive dysfunction. Recent work has included the study of oxidation products of bilirubin as a cause of cerebral vasospasm and methods to modulate the clotting pathway. He is also part of the University of Cincinnati’s sports concussion team, participating in clinical research with university athletes trying to prevent, diagnose and treat concussion. Search Pub Med for publications (search "Clark-JF after 1989")

Daniel Pomeranz Krummel, PhD
Associate Professor of Neurology & Rehabilitation Medicine
Pomeranz Krummel is a scientist with a long-standing research interest in gene expression mechanisms and collaborates closely in the Neurology department with Sengupta in research on membrane transport proteins in cancer development and as anti-cancer targets. He is a member of the Neuro-Oncology laboratory.

LinkedIn: Daniel Pomeranz Krummel LinkedIn

John Quinlan, MD
Professor of Neurology
Quinlan is interested in clinically oriented treatment studies using the mdx (dystrophin-deficient) mouse. Recent work includes a study of a non-toxic membrane stabilizer to prevent muscle breakdown during running stress. Search Pub Med for publications (search "Quinlan-J")

Soma Sengupta, MD, PhD, FRCP
Associate Professor of Neurology & Rehabilitation Medicine; Medical Director, Division of Neuro-Oncology; Harold C. Schott Endowed Chair of Molecular Therapeutics; Co-Director, Brain Tumor Center, Gardner Neuroscience Institute; Faculty Affiliate, Center for Integrative Health and Wellness
Sengupta is a clinican-scientist. Clinically, she manages adult brain tumors and adult survivors of pediatric brain cancers. She has a strong clinical interest in investigator-initiated trials, to bring much needed new treatments for these patient populations. She has a long-standing research interest in membrane transport proteins and a major part of her lab is studying such proteins as anti-cancer targets as well as their role in development of disparate cancers. She is a member of the Neuro-Oncology laboratory.

LinkedIn: Soma Sengupta LinkedIn

Kim Seroogy, PhD
Professor of Neurology
Seroogy is interested in the detrimental effects of stress-induced depression on the course of Parkinson’s disease. He also studies the organization, plasticity and neuroprotective roles of neurotrophic factors in the normal and injured dopaminergic mesostriatal system and trophic factor therapies in models of Parkinson's disease. Search Pub Med for publications (search "Seroogy-K")

Shari Wade, PhD
Professor of Pediatric PM&R, Cincinnati Children’s Hospital Medical Center
Wade is internationally renowned for her work with family functioning after pediatric TBI. Search Pub Med for publications (search "Wade-S").