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Medical Sciences Baccalaureate Program

Fundamentals of Molecular Genetics

MEDS 3021  |  3 credit hours

Fall Semester  | Syllabus (PDF)

MWF 1:30 – 2:25 PM

Anil Menon, PhD  |  anil.menon@uc.edu  |  513-558-5534
David Wieczorek, PhD  |  david.wieczorek@uc.edu  |  513-558-0058



Fundamentals of Molecular Genetics is designed for upper level undergraduates (along with graduate students, and aspiring and current medical professionals) with an interest in human genetic disease and its etiology at the molecular level. We emphasize five core areas:

  • Molecular Mechanisms—Including transcription, DNA replication, translation, DNA variation and gene environment interactions
  • Methods and Techniques—An introduction to understanding and using methods for molecular analysis and disease diagnostics
  • DNA Forensics—The fundamentals of using DNA variation in humans for forensic applications
  • Animal Models—The use of gene targeting and transgenic approaches to generating animal models for human disease
  • Gene Therapy—Modern applications in the treatment of disease using gene delivery vectors and stem cells.

This course also provides preparation for students taking nationally administered exams such as GRE, MCAT and PCAT.

 

Molecular Visualizations of DNA

Watch the YouTube video Molecular Visualizations of DNA by Drew Berry of The Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia:

 

Textbooks

Benjamin Pierce (2014) Genetics: A Conceptual Approach, 5th edition, W.H. Freeman, New York
Hardback ISBN: 978-1-4641-0946-1

Jung H Choi, Mark E McCallum (2014) Solutions and Problem-Solving Manual (to Accompany Genetics: A Conceptual Approach), 5th edition, W.H. Freeman, New York
ISBN: 978-1-4641-5092-0

Test tubes in a research lab.