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Li Zhang

Associate Professor

Environmental and Public Health Sciences | College of Medicine

  • PHD: University of North Carolina at Chapel Hill (Computational Structural Biology; Bioinformatics.)
  • Master of Science: Tsinghua University (Biophysics)
  • Bachelor Degree: Wuhan University (Physics)
Contact Information
Research Interests

Research interests: Bioinformatics, particularly in the field of cancer genomics using deep learning and systems biology. Development of analytical pipelines that process genomic sequencing data to extract genetic, epi-genetic and transcriptomic information for cancer research. Current projects include: (1) Pattern recognition in massive genomic data using deep learning; (2) Data analysis and visualization of single cell RNAseq data; (3) Integrative genomic analysis of bl...

Peer Reviewed Publications

Guo, Charles C; Bondaruk, Jolanta; Yao, Hui; Wang, Ziqiao; Zhang, Li; Lee, Sangkyou; Lee, June-Goo; Cogdell, David; Zhang, Miao; Yang, Guoliang; Dadhania, Vipulkumar; Choi, Woonyoung; Wei, Peng; Gao, Jianjun; Theodorescu, Dan; Logothetis, Christopher; Dinney, Colin; Kimmel, Marek; Weinstein, John N; McConkey, David J; Czerniak, Bogdan 2020. Assessment of Luminal and Basal Phenotypes in Bladder Cancer. Scientific reports, 10 1, 9743

Guo, Charles C; Majewski, Tadeusz; Zhang, Li; Yao, Hui; Bondaruk, Jolanta; Wang, Yan; Zhang, Shizhen; Wang, Ziqiao; Lee, June Goo; Lee, Sangkyou; Cogdell, David; Zhang, Miao; Wei, Peng; Grossman, H Barton; Kamat, Ashish; Duplisea, Jonathan James; Ferguson, James Edward; Huang, He; Dadhania, Vipulkumar; Gao, Jianjun; Dinney, Colin; Weinstein, John N; Baggerly, Keith; McConkey, David; Czerniak, Bogdan 2019. Dysregulation of EMT Drives the Progression to Clinically Aggressive Sarcomatoid Bladder Cancer. Cell reports, 27 6, 1781-1793.e4

Fox, Melanie D; Xiao, Li; Zhang, Miao; Kamat, Ashish M; Siefker-Radtke, Arlene; Zhang, Li; Dinney, Colin P; Czerniak, Bogdan; Guo, Charles C 2017. Plasmacytoid Urothelial Carcinoma of the Urinary Bladder: A Clinicopathologic and Immunohistochemical Analysis of 49 Cases. American journal of clinical pathology, 147 5, 500-506

Mobley, Aaron; Zhang, Shizhen; Bondaruk, Jolanta; Wang, Yan; Majewski, Tadeusz; Caraway, Nancy P; Huang, Li; Shoshan, Einav; Velazquez-Torres, Guermarie; Nitti, Giovanni; Lee, Sangkyou; Lee, June Goo; Fuentes-Mattei, Enrique; Willis, Daniel; Zhang, Li; Guo, Charles C; Yao, Hui; Baggerly, Keith; Lotan, Yair; Lerner, Seth P; Dinney, Colin; McConkey, David; Bar-Eli, Menashe; Czerniak, Bogdan 2017. Aurora Kinase A is a Biomarker for Bladder Cancer Detection and Contributes to its Aggressive Behavior. Scientific reports, 7 , 40714

Dadhania, Vipulkumar; Zhang, Miao; Zhang, Li; Bondaruk, Jolanta; Majewski, Tadeusz; Siefker-Radtke, Arlene; Guo, Charles C; Dinney, Colin; Cogdell, David E; Zhang, Shizhen; Lee, Sangkyou; Lee, June G; Weinstein, John N; Baggerly, Keith; McConkey, David; Czerniak, Bogdan 2016. Meta-Analysis of the Luminal and Basal Subtypes of Bladder Cancer and the Identification of Signature Immunohistochemical Markers for Clinical Use. EBioMedicine, 12 , 105-117

Guo, Charles Chuanhai; Dadhania, Vipulkumar; Zhang, Li; Majewski, Tadeusz; Bondaruk, Jolanta; Sykulski, Maciej; Wronowska, Weronika; Gambin, Anna; Wang, Yan; Zhang, Shizhen; Fuentes-Mattei, Enrique; Kamat, Ashish Madhav; Dinney, Colin; Siefker-Radtke, Arlene; Choi, Woonyoung; Baggerly, Keith A; McConkey, David; Weinstein, John N; Czerniak, Bogdan 2016. Gene Expression Profile of the Clinically Aggressive Micropapillary Variant of Bladder Cancer. European urology, 70 4, 611-620

Tetzlaff, Michael T; Singh, Rajesh R; Seviour, Elena G; Curry, Jonathan L; Hudgens, Courtney W; Bell, Diana; Wimmer, Daniel A; Ning, Jing; Czerniak, Bogdan A; Zhang, Li; Davies, Michael A; Prieto, Victor G; Broaddus, Russell R; Ram, Prahlad; Luthra, Rajyalakshmi; Esmaeli, Bita 2016. Next-generation sequencing identifies high frequency of mutations in potentially clinically actionable genes in sebaceous carcinoma. The Journal of pathology, 240 1, 84-95