Today is

Department of

Medical Education

Photo of Stephan Glasser

Stephan Glasser

Contact Information

Peer Reviewed Publications

Display All

Glasser, Stephan W; Hagood, James S; Wong, Simon; Taype, Carmen A; Madala, Satish K; Hardie, William D 2016. Mechanisms of Lung Fibrosis Resolution. The American journal of pathology, 186 5, 1066-77

Glasser, Stephan W; Maxfield, Melissa D; Ruetschilling, Teah L; Akinbi, Henry T; Baatz, John E; Kitzmiller, Joseph A; Page, Kristen; Xu, Yan; Bao, Erik L; Korfhagen, Thomas R 2013. Persistence of LPS-induced lung inflammation in surfactant protein-C-deficient mice. American journal of respiratory cell and molecular biology, 49 5, 845-54

Glasser, Stephan W; Senft, Albert P; Maxfield, Melissa D; Ruetschilling, Teah L; Baatz, John E; Page, Kristen; Korfhagen, Thomas R 2013. Genetic replacement of surfactant protein-C reduces respiratory syncytial virus induced lung injury. Respiratory research, 14 , 19

Wortham, Brian W; Eppert, Bryan L; Motz, Greg T; Flury, Jennifer L; Orozco-Levi, Mauricio; Hoebe, Kasper; Panos, Ralph J; Maxfield, Melissa; Glasser, Stephan W; Senft, Albert P; Raulet, David H; Borchers, Michael T 2012. NKG2D mediates NK cell hyperresponsiveness and influenza-induced pathologies in a mouse model of chronic obstructive pulmonary disease. Journal of immunology (Baltimore, Md. : 1950), 188 9, 4468-75

Glasser, Stephan W; Senft, Albert P 2011. Use of transgenic mouse models to understand the origins of familial pulmonary fibrosis. Current pharmaceutical biotechnology, 12 9, 1447-54

Madala, Satish K; Maxfield, Melissa D; Davidson, Cynthia R; Schmidt, Stephanie M; Garry, Daniel; Ikegami, Machiko; Hardie, William D; Glasser, Stephan W 2011. Rapamycin Regulates Bleomycin-Induced Lung Damage in SP-C-Deficient Mice. Pulmonary medicine, 2011 , 653524

Glasser, Stephan W; Hardie, William D; Hagood, James S 2010. Pathogenesis of Interstitial Lung Disease in Children and Adults. Pediatric allergy, immunology, and pulmonology, 23 1, 9-14

Glasser, Stephan W; Witt, Teah L; Senft, Albert P; Baatz, John E; Folger, Dusti; Maxfield, Melissa D; Akinbi, Henry T; Newton, Danforth A; Prows, Daniel R; Korfhagen, Thomas R 2009. Surfactant protein C-deficient mice are susceptible to respiratory syncytial virus infection. American journal of physiology. Lung cellular and molecular physiology, 297 1, L64-72

Hardie, William D; Glasser, Stephan W; Hagood, James S 2009. Emerging concepts in the pathogenesis of lung fibrosis. The American journal of pathology, 175 1, 3-16

Glasser, Stephan W; Senft, Albert P; Whitsett, Jeffrey A; Maxfield, Melissa D; Ross, Gary F; Richardson, Theresa R; Prows, Daniel R; Xu, Yan; Korfhagen, Thomas R 2008. Macrophage dysfunction and susceptibility to pulmonary Pseudomonas aeruginosa infection in surfactant protein C-deficient mice. Journal of immunology (Baltimore, Md. : 1950), 181 1, 621-8

Glasser, Stephan W; Nogee, Lawrence M 2006. Genetically engineered mice in understanding the basis of neonatal lung disease. Seminars in perinatology, 30 6, 341-9

Glasser, Stephan W; Eszterhas, Susan K; Detmer, Emily A; Maxfield, Melissa D; Korfhagen, Thomas R 2005. The murine SP-C promoter directs type II cell-specific expression in transgenic mice. American journal of physiology. Lung cellular and molecular physiology, 288 4, L625-32

Lawson, William E; Polosukhin, Vasiliy V; Stathopoulos, Georgios T; Zoia, Ornella; Han, Wei; Lane, Kirk B; Li, Bo; Donnelly, Edwin F; Holburn, George E; Lewis, Kenneth G; Collins, Robert D; Hull, William M; Glasser, Stephan W; Whitsett, Jeffrey A; Blackwell, Timothy S 2005. Increased and prolonged pulmonary fibrosis in surfactant protein C-deficient mice following intratracheal bleomycin. The American journal of pathology, 167 5, 1267-77

Glasser, Stephan W; Detmer, Emily A; Ikegami, Machiko; Na, Cheng-Lun; Stahlman, Mildred T; Whitsett, Jeffrey A 2003. Pneumonitis and emphysema in sp-C gene targeted mice. The Journal of biological chemistry, 278 16, 14291-8

Ikegami, Machiko; Weaver, Timothy E; Conkright, Juliana J; Sly, Peter D; Ross, Gary F; Whitsett, Jeffrey A; Glasser, Stephan W 2002. Deficiency of SP-B reveals protective role of SP-C during oxygen lung injury. Journal of applied physiology (Bethesda, Md. : 1985), 92 2, 519-26

Liu, Cong; Glasser, Stephan W; Wan, Huajing; Whitsett, Jeffrey A 2002. GATA-6 and thyroid transcription factor-1 directly interact and regulate surfactant protein-C gene expression. The Journal of biological chemistry, 277 6, 4519-25

Conkright, J J; Bridges, J P; Na, C L; Voorhout, W F; Trapnell, B; Glasser, S W; Weaver, T E 2001. Secretion of surfactant protein C, an integral membrane protein, requires the N-terminal propeptide. The Journal of biological chemistry, 276 18, 14658-64

Glasser, S W; Burhans, M S; Korfhagen, T R; Na, C L; Sly, P D; Ross, G F; Ikegami, M; Whitsett, J A 2001. Altered stability of pulmonary surfactant in SP-C-deficient mice. Proceedings of the National Academy of Sciences of the United States of America, 98 11, 6366-71

Whitsett, J A; Glasser, S W; Tichelaar, J W; Perl, A K; Clark, J C; Wert, S E 2001. Transgenic models for study of lung morphogenesis and repair: Parker B. Francis lecture. Chest, 120 1 Suppl, 27S-30S

Glasser, S W; Burhans, M S; Eszterhas, S K; Bruno, M D; Korfhagen, T R 2000. Human SP-C gene sequences that confer lung epithelium-specific expression in transgenic mice. American journal of physiology. Lung cellular and molecular physiology, 278 5, L933-45

Whitsett, J A; Glasser, S W 1998. Regulation of surfactant protein gene transcription. Biochimica et biophysica acta, 1408 2-3, 303-11

Bachurski, C J; Kelly, S E; Glasser, S W; Currier, T A 1997. Nuclear factor I family members regulate the transcription of surfactant protein-C. The Journal of biological chemistry, 272 52, 32759-66

Hardie, W D; Kerlakian, C B; Bruno, M D; Huelsman, K M; Wert, S E; Glasser, S W; Whitsett, J A; Korfhagen, T R 1996. Reversal of lung lesions in transgenic transforming growth factor alpha mice by expression of mutant epidermal growth factor receptor. American journal of respiratory cell and molecular biology, 15 4, 499-508

Kelly, S E; Bachurski, C J; Burhans, M S; Glasser, S W 1996. Transcription of the lung-specific surfactant protein C gene is mediated by thyroid transcription factor 1. The Journal of biological chemistry, 271 12, 6881-8

Korfhagen, T R; Bruno, M D; Ross, G F; Huelsman, K M; Ikegami, M; Jobe, A H; Wert, S E; Stripp, B R; Morris, R E; Glasser, S W; Bachurski, C J; Iwamoto, H S; Whitsett, J A 1996. Altered surfactant function and structure in SP-A gene targeted mice. Proceedings of the National Academy of Sciences of the United States of America, 93 18, 9594-9

Bachurski, C J; Pryhuber, G S; Glasser, S W; Kelly, S E; Whitsett, J A 1995. Tumor necrosis factor-alpha inhibits surfactant protein C gene transcription. The Journal of biological chemistry, 270 33, 19402-7

Baatz, J E; Bruno, M D; Ciraolo, P J; Glasser, S W; Stripp, B R; Smyth, K L; Korfhagen, T R 1994. Utilization of modified surfactant-associated protein B for delivery of DNA to airway cells in culture. Proceedings of the National Academy of Sciences of the United States of America, 91 7, 2547-51

Glasser, S W; Korfhagen, T R; Wert, S E; Whitsett, J A 1994. Transgenic models for study of pulmonary development and disease. The American journal of physiology, 267 5 Pt 1, L489-97

Korfhagen, T R; Glasser, S W; Stripp, B R 1994. Regulation of gene expression in the lung. Current opinion in pediatrics, 6 3, 255-61

Korfhagen, T R; Swantz, R J; Wert, S E; McCarty, J M; Kerlakian, C B; Glasser, S W; Whitsett, J A 1994. Respiratory epithelial cell expression of human transforming growth factor-alpha induces lung fibrosis in transgenic mice. The Journal of clinical investigation, 93 4, 1691-9

Wert, S E; Glasser, S W; Korfhagen, T R; Whitsett, J A 1993. Transcriptional elements from the human SP-C gene direct expression in the primordial respiratory epithelium of transgenic mice. Developmental biology, 156 2, 426-43

Korfhagen, T R; Bruno, M D; Glasser, S W; Ciraolo, P J; Whitsett, J A; Lattier, D L; Wikenheiser, K A; Clark, J C 1992. Murine pulmonary surfactant SP-A gene: cloning, sequence, and transcriptional activity. The American journal of physiology, 263 5 Pt 1, L546-54

Moore, K J; D'Amore-Bruno, M A; Korfhagen, T R; Glasser, S W; Whitsett, J A; Jenkins, N A; Copeland, N G 1992. Chromosomal localization of three pulmonary surfactant protein genes in the mouse. Genomics, 12 2, 388-93

Wispé, J R; Warner, B B; Clark, J C; Dey, C R; Neuman, J; Glasser, S W; Crapo, J D; Chang, L Y; Whitsett, J A 1992. Human Mn-superoxide dismutase in pulmonary epithelial cells of transgenic mice confers protection from oxygen injury. The Journal of biological chemistry, 267 33, 23937-41

Glasser, S W; Korfhagen, T R; Wert, S E; Bruno, M D; McWilliams, K M; Vorbroker, D K; Whitsett, J A 1991. Genetic element from human surfactant protein SP-C gene confers bronchiolar-alveolar cell specificity in transgenic mice. The American journal of physiology, 261 4 Pt 1, L349-56

Korfhagen, T R; Glasser, S W; Bruno, M D; McMahan, M J; Whitsett, J A 1991. A portion of the human surfactant protein A (SP-A) gene locus consists of a pseudogene. American journal of respiratory cell and molecular biology, 4 5, 463-9

Glasser, S W; Korfhagen, T R; Bruno, M D; Dey, C; Whitsett, J A 1990. Structure and expression of the pulmonary surfactant protein SP-C gene in the mouse. The Journal of biological chemistry, 265 35, 21986-91

Korfhagen, T R; Glasser, S W; Wert, S E; Bruno, M D; Daugherty, C C; McNeish, J D; Stock, J L; Potter, S S; Whitsett, J A 1990. Cis-acting sequences from a human surfactant protein gene confer pulmonary-specific gene expression in transgenic mice. Proceedings of the National Academy of Sciences of the United States of America, 87 16, 6122-6

Pilot-Matias, T J; Kister, S E; Fox, J L; Kropp, K; Glasser, S W; Whitsett, J A 1989. Structure and organization of the gene encoding human pulmonary surfactant proteolipid SP-B. DNA (Mary Ann Liebert, Inc.), 8 2, 75-86

Glasser, S W; Korfhagen, T R; Perme, C M; Pilot-Matias, T J; Kister, S E; Whitsett, J A 1988. Two SP-C genes encoding human pulmonary surfactant proteolipid. The Journal of biological chemistry, 263 21, 10326-31

Glasser, S W; Korfhagen, T R; Weaver, T E; Clark, J C; Pilot-Matias, T; Meuth, J; Fox, J L; Whitsett, J A 1988. cDNA, deduced polypeptide structure and chromosomal assignment of human pulmonary surfactant proteolipid, SPL(pVal). The Journal of biological chemistry, 263 1, 9-12

Glasser, S W; Korfhagen, T R; Weaver, T; Pilot-Matias, T; Fox, J L; Whitsett, J A 1987. cDNA and deduced amino acid sequence of human pulmonary surfactant-associated proteolipid SPL(Phe). Proceedings of the National Academy of Sciences of the United States of America, 84 12, 4007-11

Whitsett, J A; Weaver, T E; Clark, J C; Sawtell, N; Glasser, S W; Korfhagen, T R; Hull, W M 1987. Glucocorticoid enhances surfactant proteolipid Phe and pVal synthesis and RNA in fetal lung. The Journal of biological chemistry, 262 32, 15618-23