Today is

Department of

Dermatology

Photo of  Raymond Boissy, PhD

Raymond Boissy, PhD

Professor

Education/Credentials
  • Bachelor's Degree: University of Massachusetts
  • Master's Degree: University of Massachusetts
  • Doctorate Degree: University of Massachusetts
  • Post-Doc: Yale University School of Medicine

Research/Clinical Interests

Dermatology

Contact Information

Peer Reviewed Publications

Display All

Chalupa, Allison; Koshoffer, Amy; Galan, Emily; Yu, Lan; Liu, Fu-Tong; Boissy, Raymond E 2014. Melanocytic Galectin-3 is Associated with Tyrosinase Related Protein-1 and Pigment Biosynthesis. The Journal of investigative dermatology, ,

Domyan, Eric T; Guernsey, Michael W; Kronenberg, Zev; Krishnan, Shreyas; Boissy, Raymond E; Vickrey, Anna I; Rodgers, Clifford; Cassidy, Pamela; Leachman, Sancy A; Fondon, John W; Yandell, Mark; Shapiro, Michael D 2014. Epistatic and combinatorial effects of pigmentary gene mutations in the domestic pigeon. Current biology : CB, 24 4, 459-64

Mosenson, Jeffrey A; Flood, Kelsey; Klarquist, Jared; Eby, Jonathan M; Koshoffer, Amy; Boissy, Raymond E; Overbeck, Andreas; Tung, Rebecca C; Le Poole, I Caroline 2014. Preferential secretion of inducible HSP70 by vitiligo melanocytes under stress. Pigment cell & melanoma research, 27 2, 209-20

Yoshida, Hiroshi; Taguchi, Hiroyuki; Hachiya, Akira; Kitahara, Takashi; Boissy, Raymond E; Visscher, Marty O 2014. The natural trait of the curvature of human hair is correlated with bending of the hair follicle and hair bulb by a structural disparity in the root sheath. Journal of dermatological science, ,

Abu, Eme A; Su, Shengchang; Sallans, Larry; Boissy, Raymond E; Greatens, Amanda; Heineman, William R; Hassett, Daniel J 2013. Cyclic voltammetric, fluorescence and biological analysis of purified aeruginosin A, a secreted red pigment of Pseudomonas aeruginosa PAO1. Microbiology (Reading, England), 159 Pt 8, 1736-47

Ebanks, Jody P; Koshoffer, Amy; Wickett, R Randall; Hakozaki, Tomohiro; Boissy, Raymond E 2013. Hydrolytic enzymes of the interfollicular epidermis differ in expression and correlate with the phenotypic difference observed between light and dark skin. The Journal of dermatology, 40 1, 27-33

Gilbert, Emily R; Eby, Jonathan M; Hammer, Adam M; Klarquist, Jared; Christensen, David G; Barfuss, Allison J; Boissy, Raymond E; Picken, Maria M; Love, Robert B; Dilling, Daniel F; Le Poole, I Caroline 2013. Positioning ganglioside D3 as an immunotherapeutic target in lymphangioleiomyomatosis. The American journal of pathology, 183 1, 226-34

Hawkes, Jason E; Cassidy, Pamela B; Manga, Prashiela; Boissy, Raymond E; Goldgar, David; Cannon-Albright, Lisa; Florell, Scott R; Leachman, Sancy A 2013. Report of a novel OCA2 gene mutation and an investigation of OCA2 variants on melanoma risk in a familial melanoma pedigree. Journal of dermatological science, 69 1, 30-7

Lakhter, Alexander J; Kanginakudru, Sriramana; Warren, Simon; Touloukian, Christopher E; Boissy, Raymond E; Naidu, Samisubbu R 2013. Impaired PIASy-Tip60 signaling weakens activation of p53 in melanoma. Melanoma research, 23 3, 213-7

Chawla, Smita; Kvalnes, Kalla; deLong, Mitchell A; Wickett, Randall; Manga, Prashiela; Boissy, Raymond E 2012. DeoxyArbutin and its derivatives inhibit tyrosinase activity and melanin synthesis without inducing reactive oxygen species or apoptosis. Journal of drugs in dermatology : JDD, 11 10, e28-34

Boissy, R E; Nordlund, J J 2011. Vitiligo: current medical and scientific understanding. Giornale italiano di dermatologia e venereologia : organo ufficiale, Società italiana di dermatologia e sifilografia, 146 1, 69-75

Ebanks, Jody P; Koshoffer, Amy; Wickett, R Randall; Schwemberger, Sandy; Babcock, George; Hakozaki, Tomohiro; Boissy, Raymond E 2011. Epidermal keratinocytes from light vs. dark skin exhibit differential degradation of melanosomes. The Journal of investigative dermatology, 131 6, 1226-33

Hariharan, Vidhya; Klarquist, Jared; Reust, Mary J; Koshoffer, Amy; McKee, Mark D; Boissy, Raymond E; Le Poole, I Caroline 2010. Monobenzyl ether of hydroquinone and 4-tertiary butyl phenol activate markedly different physiological responses in melanocytes: relevance to skin depigmentation. The Journal of investigative dermatology, 130 1, 211-20

Kadekaro, Ana Luisa; Leachman, Sancy; Kavanagh, Renny J; Swope, Viki; Cassidy, Pamela; Supp, Dorothy; Sartor, Maureen; Schwemberger, Sandy; Babcock, George; Wakamatsu, Kazumasa; Ito, Shosuke; Koshoffer, Amy; Boissy, Raymond E; Manga, Prashiela; Sturm, Richard A; Abdel-Malek, Zalfa A 2010. Melanocortin 1 receptor genotype: an important determinant of the damage response of melanocytes to ultraviolet radiation. The FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 24 10, 3850-60

Boissy, Raymond E; Spritz, Richard A 2009. Frontiers and controversies in the pathobiology of vitiligo: separating the wheat from the chaff. Experimental dermatology, 18 7, 583-5

Ebanks, Jody P; Wickett, R Randall; Boissy, Raymond E 2009. Mechanisms regulating skin pigmentation: the rise and fall of complexion coloration. International journal of molecular sciences, 10 9, 4066-87

Hachiya, Akira; Sriwiriyanont, Penkanok; Fujimura, Tsutomu; Ohuchi, Atsushi; Kitahara, Takashi; Takema, Yoshinori; Kitzmiller, William J; Visscher, Marty O; Tsuboi, Ryoji; Boissy, Raymond E 2009. Mechanistic effects of long-term ultraviolet B irradiation induce epidermal and dermal changes in human skin xenografts. The American journal of pathology, 174 2, 401-13

Hachiya, Akira; Sriwiriyanont, Penkanok; Kobayashi, Takeshi; Nagasawa, Azumi; Yoshida, Hiroshi; Ohuchi, Atsushi; Kitahara, Takashi; Visscher, Marty O; Takema, Yoshinori; Tsuboi, Ryoji; Boissy, Raymond E 2009. Stem cell factor-KIT signalling plays a pivotal role in regulating pigmentation in mammalian hair. The Journal of pathology, 218 1, 30-9

Klarquist, Jared; Barfuss, Allison; Kandala, Sridhar; Reust, Mary J; Braun, Ruedi K; Hu, Jennifer; Dilling, Daniel F; McKee, Mark D; Boissy, Raymond E; Love, Robert B; Nishimura, Michael I; Le Poole, I Caroline 2009. Melanoma-associated antigen expression in lymphangioleiomyomatosis renders tumor cells susceptible to cytotoxic T cells. The American journal of pathology, 175 6, 2463-72

Chawla, S; deLong, M A; Visscher, M O; Wickett, R R; Manga, P; Boissy, R E 2008. Mechanism of tyrosinase inhibition by deoxyArbutin and its second-generation derivatives. The British journal of dermatology, 159 6, 1267-74

Kasamatsu, Shinya; Hachiya, Akira; Higuchi, Kazuhiko; Ohuchi, Atsushi; Kitahara, Takashi; Boissy, Raymond E 2008. Production of the soluble form of KIT, s-KIT, abolishes stem cell factor-induced melanogenesis in human melanocytes. The Journal of investigative dermatology, 128 7, 1763-72

Hachiya, A; Sriwiriyanont, P; Patel, A; Saito, N; Ohuchi, A; Kitahara, T; Takema, Y; Tsuboi, R; Boissy, R E; Visscher, M O; Wilson, J M; James, W M; Kobinger, G P 2007. Gene transfer in human skin with different pseudotyped HIV-based vectors. Gene therapy, 14 8, 648-56

Helip-Wooley, Amanda; Westbroek, Wendy; Dorward, Heidi M; Koshoffer, Amy; Huizing, Marjan; Boissy, Raymond E; Gahl, William A 2007. Improper trafficking of melanocyte-specific proteins in Hermansky-Pudlak syndrome type-5. The Journal of investigative dermatology, 127 6, 1471-8

Westbroek, Wendy; Adams, David; Huizing, Marjan; Koshoffer, Amy; Dorward, Heidi; Tinloy, Bradford; Parkes, Jennifer; Helip-Wooley, Amanda; Kleta, Robert; Tsilou, Ekaterina; Duvernay, Patrice; Digre, Kathleen B; Creel, Donnell J; White, James G; Boissy, Raymond E; Gahl, William A 2007. Cellular defects in Chediak-Higashi syndrome correlate with the molecular genotype and clinical phenotype. The Journal of investigative dermatology, 127 11, 2674-7

Yoshida, Yasuko; Hachiya, Akira; Sriwiriyanont, Penkanok; Ohuchi, Atsushi; Kitahara, Takashi; Takema, Yoshinori; Visscher, Marty O; Boissy, Raymond E 2007. Functional analysis of keratinocytes in skin color using a human skin substitute model composed of cells derived from different skin pigmentation types. The FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 21 11, 2829-39

Li, Li; Hu, Dan-Ning; Zhao, Huiquan; McCormick, Steven A; Nordlund, James J; Boissy, Raymond E 2006. Uveal melanocytes do not respond to or express receptors for alpha-melanocyte-stimulating hormone. Investigative ophthalmology & visual science, 47 10, 4507-12

Manga, Prashiela; Sheyn, David; Yang, Fan; Sarangarajan, Rangaprasad; Boissy, Raymond E 2006. A role for tyrosinase-related protein 1 in 4-tert-butylphenol-induced toxicity in melanocytes: Implications for vitiligo. The American journal of pathology, 169 5, 1652-62

Sriwiriyanont, Penkanok; Ohuchi, Atsushi; Hachiya, Akira; Visscher, Marty O; Boissy, Raymond E 2006. Interaction between stem cell factor and endothelin-1: effects on melanogenesis in human skin xenografts. Laboratory investigation; a journal of technical methods and pathology, 86 11, 1115-25

Wang, Runsheng; Tang, Phuong; Wang, Pei; Boissy, Raymond E; Zheng, Hui 2006. Regulation of tyrosinase trafficking and processing by presenilins: partial loss of function by familial Alzheimer's disease mutation. Proceedings of the National Academy of Sciences of the United States of America, 103 2, 353-8

Boissy, Raymond E; Richmond, Bonnie; Huizing, Marjan; Helip-Wooley, Amanda; Zhao, Yang; Koshoffer, Amy; Gahl, William A 2005. Melanocyte-specific proteins are aberrantly trafficked in melanocytes of Hermansky-Pudlak syndrome-type 3. The American journal of pathology, 166 1, 231-40

Boissy, Raymond E; Visscher, Marty; DeLong, Mitchell A 2005. DeoxyArbutin: a novel reversible tyrosinase inhibitor with effective in vivo skin lightening potency. Experimental dermatology, 14 8, 601-8

Greatens, Amanda; Hakozaki, Tomohiro; Koshoffer, Amy; Epstein, Howard; Schwemberger, Sandy; Babcock, George; Bissett, Donald; Takiwaki, Hirotsugu; Arase, Seiji; Wickett, R Randall; Boissy, Raymond E 2005. Effective inhibition of melanosome transfer to keratinocytes by lectins and niacinamide is reversible. Experimental dermatology, 14 7, 498-508

Helip-Wooley, Amanda; Westbroek, Wendy; Dorward, Heidi; Mommaas, Mieke; Boissy, Raymond E; Gahl, William A; Huizing, Marjan 2005. Association of the Hermansky-Pudlak syndrome type-3 protein with clathrin. BMC cell biology, 6 , 33

Kroll, Tara M; Bommiasamy, Hemamalini; Boissy, Raymond E; Hernandez, Claudia; Nickoloff, Brian J; Mestril, Ruben; Caroline Le Poole, I 2005. 4-Tertiary butyl phenol exposure sensitizes human melanocytes to dendritic cell-mediated killing: relevance to vitiligo. The Journal of investigative dermatology, 124 4, 798-806

Richmond, Bonnie; Huizing, Marjan; Knapp, Jill; Koshoffer, Amy; Zhao, Yang; Gahl, William A; Boissy, Raymond E 2005. Melanocytes derived from patients with Hermansky-Pudlak Syndrome types 1, 2, and 3 have distinct defects in cargo trafficking. The Journal of investigative dermatology, 124 2, 420-7

Smith, Justin W; Koshoffer, Amy; Morris, Randal E; Boissy, Raymond E 2005. Membranous complexes characteristic of melanocytes derived from patients with Hermansky-Pudlak syndrome type 1 are macroautophagosomal entities of the lysosomal compartment. Pigment cell research / sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society, 18 6, 417-26

Boissy, Raymond E; Manga, Prashiela 2004. On the etiology of contact/occupational vitiligo. Pigment cell research / sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society, 17 3, 208-14

Boissy, Raymond E 2003. Melanosome transfer to and translocation in the keratinocyte. Experimental dermatology, 12 Suppl 2 , 5-12

Thong, H-Y; Jee, S-H; Sun, C-C; Boissy, R E 2003. The patterns of melanosome distribution in keratinocytes of human skin as one determining factor of skin colour. The British journal of dermatology, 149 3, 498-505

Abdalkhani, Arman; Sellers, Rani; Gent, Justin; Wulitich, Heather; Childress, Sue; Stein, Barry; Boissy, Raymond E; Wysolmerski, John J; Foley, John 2002. Nipple connective tissue and its development: insights from the K14-PTHrP mouse. Mechanisms of development, 115 1-2, 63-77

Hakozaki, T; Minwalla, L; Zhuang, J; Chhoa, M; Matsubara, A; Miyamoto, K; Greatens, A; Hillebrand, G G; Bissett, D L; Boissy, R E 2002. The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer. The British journal of dermatology, 147 1, 20-31

Huizing, Marjan; Boissy, Raymond E; Gahl, William A 2002. Hermansky-Pudlak syndrome: vesicle formation from yeast to man. Pigment cell research / sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society, 15 6, 405-19

Rizvi, Tilat A; Huang, Yuan; Sidani, Amer; Atit, Radhika; Largaespada, David A; Boissy, Raymond E; Ratner, Nancy 2002. A novel cytokine pathway suppresses glial cell melanogenesis after injury to adult nerve. The Journal of neuroscience : the official journal of the Society for Neuroscience, 22 22, 9831-40

Huizing, M; Sarangarajan, R; Strovel, E; Zhao, Y; Gahl, W A; Boissy, R E 2001. AP-3 mediates tyrosinase but not TRP-1 trafficking in human melanocytes. Molecular biology of the cell, 12 7, 2075-85

Le Poole, I C; Sarangarajan, R; Zhao, Y; Stennett, L S; Brown, T L; Sheth, P; Miki, T; Boissy, R E 2001. 'VIT1', a novel gene associated with vitiligo. Pigment cell research / sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society, 14 6, 475-84

Manga, P; Boissy, R E; Pifko-Hirst, S; Zhou, B K; Orlow, S J 2001. Mislocalization of melanosomal proteins in melanocytes from mice with oculocutaneous albinism type 2. Experimental eye research, 72 6, 695-710

Minwalla, L; Zhao, Y; Cornelius, J; Babcock, G F; Wickett, R R; Le Poole, I C; Boissy, R E 2001. Inhibition of melanosome transfer from melanocytes to keratinocytes by lectins and neoglycoproteins in an in vitro model system. Pigment cell research / sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society, 14 3, 185-94

Minwalla, L; Zhao, Y; Le Poole, I C; Wickett, R R; Boissy, R E 2001. Keratinocytes play a role in regulating distribution patterns of recipient melanosomes in vitro. The Journal of investigative dermatology, 117 2, 341-7

Sarangarajan, R; Boissy, R E 2001. Tyrp1 and oculocutaneous albinism type 3. Pigment cell research / sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society, 14 6, 437-44

Sarangarajan, R; Budev, A; Zhao, Y; Gahl, W A; Boissy, R E 2001. Abnormal translocation of tyrosinase and tyrosinase-related protein 1 in cutaneous melanocytes of Hermansky-Pudlak Syndrome and in melanoma cells transfected with anti-sense HPS1 cDNA. The Journal of investigative dermatology, 117 3, 641-6

Sarangarajan, R; Shumaker, H; Soleimani, M; Le Poole, C; Boissy, R E 2001. Molecular and functional characterization of sodium--hydrogen exchanger in skin as well as cultured keratinocytes and melanocytes. Biochimica et biophysica acta, 1511 1, 181-92

Le Poole, I C; Boissy, R E; Sarangarajan, R; Chen, J; Forristal, J J; Sheth, P; Westerhof, W; Babcock, G; Das, P K; Saelinger, C B 2000. PIG3V, an immortalized human vitiligo melanocyte cell line, expresses dilated endoplasmic reticulum. In vitro cellular & developmental biology. Animal, 36 5, 309-19

Pickens, W L; Warner, R R; Boissy, Y L; Boissy, R E; Hoath, S B 2000. Characterization of vernix caseosa: water content, morphology, and elemental analysis. The Journal of investigative dermatology, 115 5, 875-81

Sarangarajan, R; Zhao, Y; Babcock, G; Cornelius, J; Lamoreux, M L; Boissy, R E 2000. Mutant alleles at the brown locus encoding tyrosinase-related protein-1 (TRP-1) affect proliferation of mouse melanocytes in culture. Pigment cell research / sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society, 13 5, 337-44

Yang, F; Sarangarajan, R; Le Poole, I C; Medrano, E E; Boissy, R E 2000. The cytotoxicity and apoptosis induced by 4-tertiary butylphenol in human melanocytes are independent of tyrosinase activity. The Journal of investigative dermatology, 114 1, 157-64

Introne, W; Boissy, R E; Gahl, W A 1999. Clinical, molecular, and cell biological aspects of Chediak-Higashi syndrome. Molecular genetics and metabolism, 68 2, 283-303

Le Poole, I C; Yang, F; Brown, T L; Cornelius, J; Babcock, G F; Das, P K; Boissy, R E 1999. Altered gene expression in melanocytes exposed to 4-tertiary butyl phenol (4-TBP): upregulation of the A2b adenosine receptor 1. The Journal of investigative dermatology, 113 5, 725-31

Tripathi, R K; Flanders, D J; Young, T L; Oetting, W S; Ramaiah, A; King, R A; Boissy, R E; Nordlund, J J 1999. Microphthalmia-associated transcription factor (MITF) locus lacks linkage to human vitiligo or osteopetrosis: an evaluation. Pigment cell research / sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society, 12 3, 187-92

Wood, J M; Jimbow, K; Boissy, R E; Slominski, A; Plonka, P M; Slawinski, J; Wortsman, J; Tosk, J 1999. What's the use of generating melanin? Experimental dermatology, 8 2, 153-64

Yang, F; Boissy, R E 1999. Effects of 4-tertiary butylphenol on the tyrosinase activity in human melanocytes. Pigment cell research / sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society, 12 4, 237-45

Boissy, R E; Sakai, C; Zhao, H; Kobayashi, T; Hearing, V J 1998. Human tyrosinase related protein-1 (TRP-1) does not function as a DHICA oxidase activity in contrast to murine TRP-1. Experimental dermatology, 7 4, 198-204

Boissy, R E; Zhao, Y; Gahl, W A 1998. Altered protein localization in melanocytes from Hermansky-Pudlak syndrome: support for the role of the HPS gene product in intracellular trafficking. Laboratory investigation; a journal of technical methods and pathology, 78 9, 1037-48

Carden, S M; Boissy, R E; Schoettker, P J; Good, W V 1998. Albinism: modern molecular diagnosis. The British journal of ophthalmology, 82 2, 189-95

Collawn, S S; Boissy, R E; Gamboa, M; Vasconez, L O 1998. Ultrastructural study of the skin after facial chemical peels and the effect of moisturization on wound healing. Plastic and reconstructive surgery, 101 5, 1374-9; discussion 1

Collawn, S S; Boissy, R E; Vasconez, L O 1998. Skin ultrastructure after CO2 laser resurfacing. Plastic and reconstructive surgery, 102 2, 509-15

Cieszka, K; Hill, H Z; Xin, P; Azure, M; Hill, G J; Meyenhofer, M F; Boissy, R E; Mitchell, D L 1997. Survival of Cloudman mouse melanoma cells after irradiation by solar wavelengths of light. Pigment cell research / sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society, 10 4, 193-200

Hill, H Z; Hill, G J; Cieszka, K; Plonka, P M; Mitchell, D L; Meyenhofer, M F; Xin, P; Boissy, R E 1997. Comparative action spectrum for ultraviolet light killing of mouse melanocytes from different genetic coat color backgrounds. Photochemistry and photobiology, 65 6, 983-9

Le Poole, C; Boissy, R E 1997. Vitiligo. Seminars in cutaneous medicine and surgery, 16 1, 3-14

Boissy, R E; Zhao, H; Oetting, W S; Austin, L M; Wildenberg, S C; Boissy, Y L; Zhao, Y; Sturm, R A; Hearing, V J; King, R A; Nordlund, J J 1996. Mutation in and lack of expression of tyrosinase-related protein-1 (TRP-1) in melanocytes from an individual with brown oculocutaneous albinism: a new subtype of albinism classified as "OCA3". American journal of human genetics, 58 6, 1145-56

Donatien, P D; Diment, S L; Boissy, R E; Orlow, S J 1996. Melanosomal and lysosomal alterations in murine melanocytes following transfection with the v-rasHa oncogene. International journal of cancer. Journal international du cancer, 66 4, 557-63

Nagle, D L; Karim, M A; Woolf, E A; Holmgren, L; Bork, P; Misumi, D J; McGrail, S H; Dussault, B J; Perou, C M; Boissy, R E; Duyk, G M; Spritz, R A; Moore, K J 1996. Identification and mutation analysis of the complete gene for Chediak-Higashi syndrome. Nature genetics, 14 3, 307-11

Zhao, H; Eling, D J; Medrano, E E; Boissy, R E 1996. Retroviral infection with human tyrosinase-related protein-1 (TRP-1) cDNA upregulates tyrosinase activity and melanin synthesis in a TRP-1-deficient melanoma cell line. The Journal of investigative dermatology, 106 4, 744-52

Austin, L M; Boissy, R E 1995. Mammalian tyrosinase-related protein-1 is recognized by autoantibodies from vitiliginous Smyth chickens. An avian model for human vitiligo. The American journal of pathology, 146 6, 1529-41

Beermann, F; Orlow, S J; Boissy, R E; Schmidt, A; Boissy, Y L; Lamoreux, M L 1995. Misrouting of tyrosinase with a truncated cytoplasmic tail as a result of the murine platinum (cp) mutation. Experimental eye research, 61 5, 599-607

Boissy, R E; Lamoreux, M L 1995. In vivo and in vitro morphological analysis of melanocytes homozygous for the misp allele at the murine microphthalmia locus. Pigment cell research / sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society, 8 6, 294-301

Farooqui, J Z; Medrano, E E; Boissy, R E; Tigelaar, R E; Nordlund, J J 1995. Thy-1+ dendritic cells express truncated form of POMC mRNA. Experimental dermatology, 4 5, 297-301

Zhao, H; Boissy, R E 1994. Distinguishing between the catalytic potential and apparent expression of tyrosinase activities. The American journal of the medical sciences, 308 6, 322-30

Zhao, H; Boissy, Y L; Abdel-Malek, Z; King, R A; Nordlund, J J; Boissy, R E 1994. On the analysis of the pathophysiology of Chediak-Higashi syndrome. Defects expressed by cultured melanocytes. Laboratory investigation; a journal of technical methods and pathology, 71 1, 25-34

Zhao, H; Zhao, Y; Nordlund, J J; Boissy, R E 1994. Human TRP-1 has tyrosine hydroxylase but no dopa oxidase activity. Pigment cell research / sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society, 7 3, 131-40

Boissy, R E; Boissy, Y L; Krakowsky, J M; Lamoreux, M L; Lingrel, J B; Nordlund, J J 1993. Ocular pathology in mice with a transgenic insertion at the microphthalmia locus. Journal of submicroscopic cytology and pathology, 25 3, 319-32

Farooqui, J Z; Auclair, B W; Robb, E; Sarkisian, E; Cooper, C; Alexander, J W; Warden, G; Boissy, R E; Norlund, J 1993. Histological, biochemical, and ultrastructural studies on hyperpigmented human skin xenografts. Pigment cell research / sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society, 6 4 Pt 1, 226-33

Krakowsky, J M; Boissy, R E; Neumann, J C; Lingrel, J B 1993. A DNA insertional mutation results in microphthalmia in transgenic mice. Transgenic research, 2 1, 14-20

Medrano, E E; Farooqui, J Z; Boissy, R E; Boissy, Y L; Akadiri, B; Nordlund, J J 1993. Chronic growth stimulation of human adult melanocytes by inflammatory mediators in vitro: implications for nevus formation and initial steps in melanocyte oncogenesis. Proceedings of the National Academy of Sciences of the United States of America, 90 5, 1790-4

Orlow, S J; Boissy, R E; Moran, D J; Pifko-Hirst, S 1993. Subcellular distribution of tyrosinase and tyrosinase-related protein-1: implications for melanosomal biogenesis. The Journal of investigative dermatology, 100 1, 55-64

Orlow, S J; Zhou, B K; Boissy, R E; Pifko-Hirst, S 1993. Identification of a mammalian melanosomal matrix glycoprotein. The Journal of investigative dermatology, 101 2, 141-4

Searle, E A; Austin, L M; Boissy, Y L; Zhao, H; Nordlund, J J; Boissy, R E 1993. Smyth chicken melanocyte autoantibodies: cross-species recognition, in vivo binding, and plasma membrane reactivity of the antiserum. Pigment cell research / sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society, 6 3, 145-57

Zhou, B K; Boissy, R E; Pifko-Hirst, S; Moran, D J; Orlow, S J 1993. Lysosome-associated membrane protein-1 (LAMP-1) is the melanocyte vesicular membrane glycoprotein band II. The Journal of investigative dermatology, 100 2, 110-4

Austin, L M; Boissy, R E; Jacobson, B S; Smyth, J R 1992. The detection of melanocyte autoantibodies in the Smyth chicken model for vitiligo. Clinical immunology and immunopathology, 64 2, 112-20

Chetty, B V; Boissy, R E; Warden, G D; Nordlund, J J 1992. Basement membrane and fibroblast aberration in blisters at the donor, graft, and spontaneously healed sites in patients with burns. Archives of dermatology, 128 2, 181-6

Boissy, R E; Beato, K E; Nordlund, J J 1991. Dilated rough endoplasmic reticulum and premature death in melanocytes cultured from the vitiligo mouse. The American journal of pathology, 138 6, 1511-25

Boissy, R E; Liu, Y Y; Medrano, E E; Nordlund, J J 1991. Structural aberration of the rough endoplasmic reticulum and melanosome compartmentalization in long-term cultures of melanocytes from vitiligo patients. The Journal of investigative dermatology, 97 3, 395-404

Boissy, R E; Trinkle, L S; Nordlund, J J 1990. Neural-tube-derived melanocyte subsets undergo commitment to their distinct lineages in culture. Cell differentiation and development : the official journal of the International Society of Developmental Biologists, 30 2, 129-45

Hoath, S B; Donnelly, M M; Boissy, R E 1990. Sensory transduction and the mammalian epidermis. Biosensors & bioelectronics, 5 5, 351-66

Hoath, S B; Pickens, W L; Sells, S F; Boissy, R E 1990. Epidermal development in the growth retarded fetal rat. Journal of developmental physiology, 13 1, 41-50

Orlow, S J; Chakraborty, A K; Boissy, R E; Pawelek, J M 1990. Inhibition of induced melanogenesis in Cloudman melanoma cells by four phenotypic modifiers. Experimental cell research, 191 2, 209-18

Boissy, R E; Trinkle, L S; Nordlund, J J 1989. Separation of pigmented and albino melanocytes and the concomitant evaluation of endogenous peroxide content using flow cytometry. Cytometry, 10 6, 779-87

Nordlund, J J; Abdel-Malek, Z A; Boissy, R E; Rheins, L A 1989. Pigment cell biology: an historical review. The Journal of investigative dermatology, 92 4 Suppl, 53S-60S

Abdel-Malek, Z A; Swope, V B; Trinkle, L S; Ferroni, E N; Boissy, R E; Nordlund, J J 1988. Alteration of the Cloudman melanoma cell cycle by prostaglandins E1 and E2 determined by using a 5-bromo-2'-deoxyuridine method of DNA analysis. Journal of cellular physiology, 136 2, 247-56

Boissy, R E 1988. The melanocyte. Its structure, function, and subpopulations in skin, eyes, and hair. Dermatologic clinics, 6 2, 161-73

Boissy, R E; Gecks, S; Smyth, J R; Nordlund, J J 1988. Ocular pathology in the minimally depigmented subline of the vitiliginous Smyth chicken. Pigment cell research / sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society, 1 5, 303-14

Boissy, R E; Lamoreux, M L 1988. Animal models of an acquired pigmentary disorder--vitiligo. Progress in clinical and biological research, 256 , 207-18

Boissy, R E; Moellmann, G E; Halaban, R 1987. Tyrosinase and acid phosphatase activities in melanocytes from avian albinos. The Journal of investigative dermatology, 88 3, 292-300

Boissy, R E; Moellmann, G E; Lerner, A B 1987. Morphology of melanocytes in hair bulbs and eyes of vitiligo mice. The American journal of pathology, 127 2, 380-8

Boissy, R E; Moellmann, G; Trainer, A T; Smyth, J R; Lerner, A B 1986. Delayed-amelanotic (DAM or Smyth) chicken: melanocyte dysfunction in vivo and in vitro. The Journal of investigative dermatology, 86 2, 149-56

Lerner, A B; Shiohara, T; Boissy, R E; Jacobson, K A; Lamoreux, M L; Moellmann, G E 1986. A mouse model for vitiligo. The Journal of investigative dermatology, 87 3, 299-304

Boissy, R E; Halaban, R 1985. Establishment of proliferative, pure cultures of pigmented chicken melanocytes from neural tubes. The Journal of investigative dermatology, 84 2, 158-61

Boissy, R E; Lamont, S J; Smyth, J R 1984. Persistence of abnormal melanocytes in immunosuppressed chickens of the autoimmune "DAM" line. Cell and tissue research, 235 3, 663-8

Boissy, R E; Smyth, J R; Fite, K V 1983. Progressive cytologic changes during the development of delayed feather amelanosis and associated choroidal defects in the DAM chicken line. A vitiligo model. The American journal of pathology, 111 2, 197-212

Lamont, S J; Boissy, R E; Smyth, J R 1982. Humoral immune response and expression of spontaneous postnatal amelanosis in DAM line chickens. Immunological communications, 11 2, 121-7

Smyth, J R; Boissy, R E; Fite, K V; Albert, D M 1981. Retinal dystrophy associated with a postnatal amelanosis in the chicken. Investigative ophthalmology & visual science, 20 6, 799-803

Boissy, R E; Nordlund, J J . Molecular basis of congenital hypopigmentary disorders in humans: a review. Pigment cell research / sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society, 10 1-2, 12-24

Boissy, Raymond E; Dell'Anna, Maria Lucia; Picardo, Mauro . On the pathophysiology of vitiligo: possible treatment options. Indian journal of dermatology, venereology and leprology, 78 1, 24-9

Hamed, Saja H; Sriwiriyanont, Penkanok; deLong, Mitchell A; Visscher, Marty O; Wickett, R Randall; Boissy, Raymond E . Comparative efficacy and safety of deoxyarbutin, a new tyrosinase-inhibiting agent. Journal of cosmetic science, 57 4, 291-308

Kitzmiller, W John; Stanton, Ryan A; Wickett, R Randall; Tolia, Gaurva; Boissy, Raymond E; Visscher, Marty O . Noninvasive skin measurements after CO(2) and erbium laser resurfacing. Aesthetic surgery journal / the American Society for Aesthetic Plastic surgery, 23 1, 20-7

Lamoreux, M L; Boissy, R E; Womack, J E; Nordlund, J J . The vit gene maps to the mi (microphthalmia) locus of the laboratory mouse. The Journal of heredity, 83 6, 435-9

Smyth, J R; Boissy, R E; Fite, K V . The DAM chicken: a model for spontaneous postnatal cutaneous and ocular amelanosis. The Journal of heredity, 72 3, 150-6

Yang, F; Abdel-Malek, Z; Boissy, R E . Effects of commonly used mitogens on the cytotoxicity of 4-tertiary butylphenol to human melanocytes. In vitro cellular & developmental biology. Animal, 35 10, 566-70