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Photo of  Helen Jones, PhD

Helen Jones, PhD

Assistant Professor of Surgery

  • Bachelor's Degree: University of St. Andrews - Scotland
  • Doctoral Degree: University of Aberdeen - Scotland
Contact Information
  • Cincinnati Children's Hospital Medical Center
  • Department of Pediatric Surgery
  • 3333 Burnet Avenue
  • Cincinnati, Ohio 45229
  • Office 513-636-6259
  • Email

Peer Reviewed Publications

Abd Ellah NH, Taylor L, Ayres N, Elmahdy MM, Fetih GN, Jones HN, Ibrahim EA, Pauletti GM 2016. NF-κB decoy polyplexes decrease P-glycoprotein-mediated multidrug resistance in colorectal cancer cells Cancer Gene Therapy, 23 5, 149-55

Chaturvedi, Vandana; Ertelt, James M; Jiang, Tony T; Kinder, Jeremy M; Xin, Lijun; Owens, Kathryn J; Jones, Helen N; Way, Sing Sing 2015. CXCR3 blockade protects against Listeria monocytogenes infection-induced fetal wastage. The Journal of clinical investigation, 125 4, 1713-25

Jones, Helen N; Olbrych, Stephanie K; Smith, Kathleen L; Cnota, James F; Habli, Mounira; Ramos-Gonzales, Osniel; Owens, Kathryn J; Hinton, Andrea C; Polzin, William J; Muglia, Louis J; Hinton, Robert B 2015. Hypoplastic left heart syndrome is associated with structural and vascular placental abnormalities and leptin dysregulation. Placenta, 36 10, 1078-86

Troja, Weston; Kil, Kicheol; Klanke, Charles; Jones, Helen N 2014. Interaction between human placental microvascular endothelial cells and a model of human trophoblasts: effects on growth cycle and angiogenic profile. Physiological reports, 2 3, e00244

Jansson, Nina; Rosario, Fredrick J; Gaccioli, Francesca; Lager, Susanne; Jones, Helen N; Roos, Sara; Jansson, Thomas; Powell, Theresa L 2013. Activation of placental mTOR signaling and amino acid transporters in obese women giving birth to large babies. The Journal of clinical endocrinology and metabolism, 98 1, 105-13

Jones, Helen N; Crombleholme, Timothy; Habli, Mounira 2013. Adenoviral-mediated placental gene transfer of IGF-1 corrects placental insufficiency via enhanced placental glucose transport mechanisms. PloS one, 8 9, e74632

Lager, Susanne; Gaccioli, Francesca; Ramirez, Vanessa I; Jones, Helen N; Jansson, Thomas; Powell, Theresa L 2013. Oleic acid stimulates system A amino acid transport in primary human trophoblast cells mediated by toll-like receptor 4. Journal of lipid research, 54 3, 725-33

Keswani, Sundeep G; Balaji, Swathi; Le, Louis; Leung, Alice; Katz, Anna B; Lim, Foong-Yen; Habli, Mounira; Jones, Helen N; Wilson, James M; Crombleholme, Timothy M 2012. Pseudotyped AAV vector-mediated gene transfer in a human fetal trachea xenograft model: implications for in utero gene therapy for cystic fibrosis. PloS one, 7 8, e43633

Wang, Kang; Dong, Hai-Qing; Wen, Hui-Yun; Xu, Meng; Li, Cao; Li, Yong-Yong; Jones, Helen N; Shi, Dong-Lu; Zhang, Xian-Zheng 2011. Novel vesicles self-assembled from amphiphilic star-armed PEG/polypeptide hybrid copolymers for drug delivery. Macromolecular bioscience, 11 1, 65-71

Jones, Helen N; Jansson, Thomas; Powell, Theresa L 2010. Full-length adiponectin attenuates insulin signaling and inhibits insulin-stimulated amino Acid transport in human primary trophoblast cells. Diabetes, 59 5, 1161-70

Jones, H N; Jansson, T; Powell, T L 2009. IL-6 stimulates system A amino acid transporter activity in trophoblast cells through STAT3 and increased expression of SNAT2. American journal of physiology. Cell physiology, 297 5, C1228-35

Jones, Helen N; Woollett, Laura A; Barbour, Nicolette; Prasad, Puttur D; Powell, Theresa L; Jansson, Thomas 2009. High-fat diet before and during pregnancy causes marked up-regulation of placental nutrient transport and fetal overgrowth in C57/BL6 mice. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 23 1, 271-8

Jones, H N; Ashworth, C J; Page, K R; McArdle, H J 2006. Expression and adaptive regulation of amino acid transport system A in a placental cell line under amino acid restriction. Reproduction (Cambridge, England), 131 5, 951-60

Jones, Helen N; Ashworth, Cheryl J; Page, Ken R; McArdle, Harry J 2006. Cortisol stimulates system A amino acid transport and SNAT2 expression in a human placental cell line (BeWo). American journal of physiology. Endocrinology and metabolism, 291 3, E596-603

Jones, H N; Powell, T L; Jansson, T . Regulation of placental nutrient transport--a review. Placenta, 28 8-9, 763-74

Keswani, Sundeep G; Balaji, Swathi; Le, Louis; Leung, Alice; Lim, Foong-Yen; Habli, Mounira; Jones, Helen N; Wilson, James M; Crombleholme, Timothy M . Pseudotyped adeno-associated viral vector tropism and transduction efficiencies in murine wound healing. Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society, 20 4, 592-600