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Department of

Surgery

Photo of  Jason Frischer, MD

Jason Frischer, MD

Associate Professor of Surgery; Director, Peña Colorectal Center, CCHMC

Education/Credentials
  • Bachelor's Degree: Cornell University
  • Medical Degree: SUNY Downstate Medical Center
  • Pediatric Surgery Research/ECMO Fellowship: Columbia University/Children's Hospital of New York
  • General Surgery Residency: Mount Sinai School of Medicine
  • Pediatric Surgery Residency: Columbia University/Children’s Hospital of New York

Board Certifications & Licenses
  • Board Certified Diplomate American Board of Surgery, 2007
  • Board Certified Diplomate American Board of Pediatric Surgery, 2010
  • Medical License State of Ohio, 2008
Contact Information
  • Division of Pediatric Surgery
  • Cincinnati Children's Hospital Medical Center
  • 3333 Burnet Avenue
  • Cincinnati, Ohio 45229
  • Office 513-636-8318
  • Email jason.frischer@cchmc.org

Peer Reviewed Publications

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Bischoff, Andrea; Frischer, Jason; Knod, Jennifer Leslie; Dickie, Belinda; Levitt, Marc A; Holder, Monica; Jackson, Lyndsey; Peña, Alberto 2017. Damaged anal canal as a cause of fecal incontinence after surgical repair for Hirschsprung disease - a preventable and under-reported complication. Journal of pediatric surgery, 52 4, 549-553

Mosiello, Giovanni; Marshall, David; Rolle, Udo; Crétolle, Célia; Santacruz, Bruno G; Frischer, Jason; Benninga, Marc A 2017. Consensus Review of Best Practice of Transanal Irrigation in Children. Journal of pediatric gastroenterology and nutrition, 64 3, 343-352

Cushing, Christopher C; Martinez-Leo, Bruno; Bischoff, Andrea; Hall, Jennifer; Helmrath, Michael; Dickie, Belinda H; Levitt, Marc A; Peña, Alberto; Zeller, Meg H; Frischer, Jason S 2016. Health-Related Quality of Life and Parental Stress in Children With Fecal Incontinence: A Normative Comparison. Journal of pediatric gastroenterology and nutrition, 63 6, 633-636

Frischer, Jason S; Rymeski, Beth 2016. Complications in colorectal surgery. Seminars in pediatric surgery, 25 6, 380-387

Knod, J Leslie; Crawford, Kelly; Dusing, Mary; Collins, Margaret H; Chernoguz, Artur; Frischer, Jason S 2016. Angiogenesis and Vascular Endothelial Growth Factor-A Expression Associated with Inflammation in Pediatric Crohn's Disease. Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 20 3, 624-30

Knod, J Leslie; Holder, Monica; Cortez, Alexander R; Martinez-Leo, Bruno; Kern, Patricia; Saeed, Shehzad; Warner, Brad; Dickie, Belinda; Falcone, Richard A; von Allmen, Daniel; Frischer, Jason S 2016. Surgical outcomes, bowel habits and quality of life in young patients after ileoanal anastomosis for ulcerative colitis. Journal of pediatric surgery, 51 8, 1246-50

Knod, Jennifer Leslie; Crawford, Kelly; Dusing, Mary; Frischer, Jason S 2016. Murine colitis treated with multitargeted tyrosine kinase inhibitors. The Journal of surgical research, 200 2, 501-7

Martinez-Leo, Bruno; Chesley, Patrick; Alam, Shumyle; Frischer, Jason S; Levitt, Marc A; Avansino, Jeffrey; Dickie, Belinda Hsi 2016. The association of the severity of anorectal malformations and intestinal malrotation. Journal of pediatric surgery, 51 8, 1241-5

Schapiro, Andrew H; Lin, Tom K; Frischer, Jason S; Silverman, Ayaka; Trout, Andrew T 2016. Extensive heterotopic gastric mucosa of the small intestine: imaging with (99m)Tc-sodium pertechnetate SPECT/CT enterography. Pediatric radiology, 46 13, 1873-1878

Bischoff, Andrea; Frischer, Jason; Dickie, Belinda H; Peña, Alberto 2014. Anorectal malformation without fistula: a defect with unique characteristics. Pediatric surgery international, 30 8, 763-6

Fernandez, Emilio; Bischoff, Andrea; Dickie, Belinda H; Frischer, Jason; Hall, Jennifer; Peña, Alberto 2014. Esophageal atresia in patients with anorectal malformations. Pediatric surgery international, 30 8, 767-71

Knod, Jennifer Leslie; Crawford, Kelly; Dusing, Mary; Frischer, Jason S 2014. Mouse strain influences angiogenic response to dextran sodium sulfate-induced colitis. The Journal of surgical research, 190 1, 47-54

Currier, Mark A; Eshun, Francis K; Sholl, Allyson; Chernoguz, Artur; Crawford, Kelly; Divanovic, Senad; Boon, Louis; Goins, William F; Frischer, Jason S; Collins, Margaret H; Leddon, Jennifer L; Baird, William H; Haseley, Amy; Streby, Keri A; Wang, Pin-Yi; Hendrickson, Brett W; Brekken, Rolf A; Kaur, Balveen; Hildeman, David; Cripe, Timothy P 2013. VEGF blockade enables oncolytic cancer virotherapy in part by modulating intratumoral myeloid cells. Molecular therapy : the journal of the American Society of Gene Therapy, 21 5, 1014-23

Eradi, Balgopal; Hamrick, Miller; Bischoff, Andrea; Frischer, Jason S; Helmrath, Michael; Hall, Jennifer; Peña, Alberto; Levitt, Marc A 2013. The role of a colon resection in combination with a Malone appendicostomy as part of a bowel management program for the treatment of fecal incontinence. Journal of pediatric surgery, 48 11, 2296-300

Knod, J Leslie; Garrison, Aaron P; Frischer, Jason S; Dickie, Belinda 2013. Foregut duplication cyst associated with esophageal atresia and tracheoesophageal fistula: a case report and literature review. Journal of pediatric surgery, 48 5, E5-7

Knod, Leslie; Donovan, Eileen C; Chernoguz, Artur; Crawford, Kelly M; Dusing, Mary R; Frischer, Jason S 2013. Vascular endothelial growth factor receptor-2 inhibition in experimental murine colitis. The Journal of surgical research, 184 1, 101-7

Landis, Melissa W; Butler, Dawn; Lim, Foong Yen; Keswani, Sundeep; Frischer, Jason; Haberman, Beth; Kingma, Paul S 2013. Octreotide for chylous effusions in congenital diaphragmatic hernia. Journal of pediatric surgery, 48 11, 2226-9

Merrow, Arnold C; Frischer, Jason S; Lucky, Anne W 2013. Pyloric atresia with epidermolysis bullosa: fetal MRI diagnosis with postnatal correlation. Pediatric radiology, 43 12, 1656-61

Barnett, Sean J; Frischer, Jason S; Gaskey, John A; Ryckman, Frederick C; von Allmen, Daniel 2012. Pediatric hernia repair: 1-stop shopping. Journal of pediatric surgery, 47 1, 213-6

Chernoguz, Artur; Crawford, Kelly; Donovan, Eileen; Vandersall, Abbey; Berglund, Caroline; Cripe, Timothy P; Frischer, Jason S 2012. EGFR inhibition fails to suppress vascular proliferation and tumor growth in a Ewing's sarcoma model. The Journal of surgical research, 173 1, 1-9

Chernoguz, Artur; Crawford, Kelly; Vandersall, Abbey; Rao, Marepalli; Willson, Tara; Denson, Lee A; Frischer, Jason S 2012. Pretreatment with anti-VEGF therapy may exacerbate inflammation in experimental acute colitis. Journal of pediatric surgery, 47 2, 347-54

Le, Louis D; Keswani, Sundeep G; Biesiada, Jacek; Lim, Foong-Yen; Kingma, Paul S; Haberman, Beth E; Frischer, Jason; Habli, Mounira; Crombleholme, Timothy M 2012. The congenital diaphragmatic hernia composite prognostic index correlates with survival in left-sided congenital diaphragmatic hernia. Journal of pediatric surgery, 47 1, 57-62

Browne, Andrew W; Leddon, Jennifer L; Currier, Mark A; Williams, Jon P; Frischer, Jason S; Collins, Margaret H; Ahn, Chong H; Cripe, Timothy P 2011. Cancer screening by systemic administration of a gene delivery vector encoding tumor-selective secretable biomarker expression. PloS one, 6 5, e19530

Keswani, Sundeep G; Le, Louis D; Morris, Lee M; Lim, Foong-Yen; Katz, Anna B; Ghobril, Nabil; Habli, Mounira; Frischer, Jason S; Crombleholme, Timothy M 2011. Submucosal gland development in the human fetal trachea xenograft model: implications for fetal gene therapy. Journal of pediatric surgery, 46 1, 33-8

Lawal, Taiwo A; Falcone, Richard A; von Allmen, Daniel; Denson, Lee A; Levitt, Marc A; Warner, Brad W; Frischer, Jason S 2011. The utility of routine pouchogram before ileostomy reversal in children and adolescents following ileal pouch anal anastomosis. Journal of pediatric surgery, 46 6, 1222-5

Lee, Timothy C; Lim, Foong Y; Keswani, Sundeep G; Frischer, Jason S; Haberman, Beth; Kingma, Paul S; Habli, Mounira; Jaekle, Ronald K; Sharp, Gina; Kline-Fath, Beth; Rubio, Eva I; Calvo, Maria; Guimaraes, Carolina; Crombleholme, Timothy M 2011. Late gestation fetal magnetic resonance imaging-derived total lung volume predicts postnatal survival and need for extracorporeal membrane oxygenation support in isolated congenital diaphragmatic hernia. Journal of pediatric surgery, 46 6, 1165-71

Bischoff, Andrea; Gupta, Anita; D'Mello, Sharon; Mezoff, Adam; Podberesky, Daniel; Barnett, Sean; Keswani, Sundeep; Frischer, Jason S 2010. Crohn's disease limited to the appendix: a case report in a pediatric patient. Pediatric surgery international, 26 11, 1125-8

Dauplaise, Derrick J N; Barnett, Sean J; Frischer, Jason S; Wong, Hector R 2010. Decompressive abdominal laparotomy for abdominal compartment syndrome in an unengrafted bone marrow recipient with septic shock. Critical care research and practice, 2010 ,

Lawal, Taiwo A; Frischer, Jason S; Falcone, Richard A; Chatoorgoon, Kaveer; Denson, Lee A; Levitt, Marc A 2010. The transanal approach with laparoscopy or laparotomy for the treatment of rectal strictures in Crohn's disease. Journal of laparoendoscopic & advanced surgical techniques. Part A, 20 9, 791-5

Vuletin, Jose F; Lim, Foong-Yen; Cnota, James; Kline-Fath, Beth; Salisbury, Shelia; Haberman, Beth; Kingma, Paul; Frischer, Jason; Crombleholme, Timothy 2010. Prenatal pulmonary hypertension index: novel prenatal predictor of severe postnatal pulmonary artery hypertension in antenatally diagnosed congenital diaphragmatic hernia. Journal of pediatric surgery, 45 4, 703-8

Ruiz-Elizalde, Alejandro R; Frischer, Jason S; Cowles, Robert A 2009. Button-loop feeding jejunostomy. Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 13 7, 1376-8

Ruiz-Elizalde, Alejandro R; Haley, Mary Jo; Fisher, Jason C; Frischer, Jason S; Zitsman, Jeffrey L 2009. Gastric tube-pericardial fistula: a remote complication of esophageal replacement for long gap esophageal atresia. Journal of pediatric surgery, 44 7, 1440-2

Kadenhe-Chiweshe, Angela; Papa, Joey; McCrudden, Kimberly W; Frischer, Jason; Bae, Jae-O; Huang, Jianzhong; Fisher, Jason; Lefkowitch, Jay H; Feirt, Nikki; Rudge, John; Holash, Jocelyn; Yancopoulos, George D; Kandel, Jessica J; Yamashiro, Darrell J 2008. Sustained VEGF blockade results in microenvironmental sequestration of VEGF by tumors and persistent VEGF receptor-2 activation. Molecular cancer research : MCR, 6 1, 1-9

Lee, Alice; Frischer, Jason; Serur, Anna; Huang, Jianzhong; Bae, Jae-O; Kornfield, Zev Noah; Eljuga, Lucy; Shawber, Carrie J; Feirt, Nikki; Mansukhani, Mahesh; Stempak, Diana; Baruchel, Sylvain; Glade Bender, Julia; Kandel, Jessica J; Yamashiro, Darrell J 2006. Inhibition of cyclooxygenase-2 disrupts tumor vascular mural cell recruitment and survival signaling. Cancer research, 66 8, 4378-84

Bae, Jae-O; Frischer, Jason S; Waich, Margarita; Addonizio, Linda J; Lazar, Eric L; Stolar, Charles J H 2005. Extracorporeal membrane oxygenation in pediatric cardiac transplantation. Journal of pediatric surgery, 40 6, 1051-6; discussion 1

Frischer, Jason S; Huang, Jianzhong; Serur, Anna; Kadenhe, Angela; Yamashiro, Darrell J; Kandel, Jessica J 2004. Biomolecular markers and involution of hemangiomas. Journal of pediatric surgery, 39 3, 400-4

Frischer, Jason S; Huang, Jianzhong; Serur, Anna; Kadenhe-Chiweshe, Angela; McCrudden, Kimberly W; O'Toole, Kathleen; Holash, Jocelyn; Yancopoulos, George D; Yamashiro, Darrell J; Kandel, Jessica J 2004. Effects of potent VEGF blockade on experimental Wilms tumor and its persisting vasculature. International journal of oncology, 25 3, 549-53

Huang, Jianzhong; Frischer, Jason S; New, Tamara; Kim, Eugene S; Serur, Anna; Lee, Alice; Kadenhe-Chiwishe, Angela; Pollyea, Daniel A; Yokoi, Akiko; Holash, Jocelyn; Yancopoulos, George D; Kandel, Jessica J; Yamashiro, Darrell J 2004. TNP-470 promotes initial vascular sprouting in xenograft tumors. Molecular cancer therapeutics, 3 3, 335-43

Huang, Jianzhong; Frischer, Jason S; Serur, Anna; Kadenhe, Angela; Yokoi, Akiko; McCrudden, Kimberly W; New, Tamara; O'Toole, Kathleen; Zabski, Stephanie; Rudge, John S; Holash, Jocelyn; Yancopoulos, George D; Yamashiro, Darrell J; Kandel, Jessica J 2003. Regression of established tumors and metastases by potent vascular endothelial growth factor blockade. Proceedings of the National Academy of Sciences of the United States of America, 100 13, 7785-90

Kaicker, Shipra; McCrudden, Kimberly W; Beck, Leal; New, Tamara; Huang, Jianzhong; Frischer, Jason S; Serur, Anna; Kadenhe-Chiweshe, Angela; Yokoi, Akiko; Kandel, Jessica J; Yamashiro, Darrell J 2003. Thalidomide is anti-angiogenic in a xenograft model of neuroblastoma. International journal of oncology, 23 6, 1651-5

McCrudden, Kimberly W; Hopkins, Benjamin; Frischer, Jason; Novikov, Anna; Huang, Jianzhong; Kadenhe, Angela; New, Tamara; Yokoi, Akiko; Yamashiro, Darrell J; Kandel, Jessica J; Middlesworth, William 2003. Anti-VEGF antibody in experimental hepatoblastoma: suppression of tumor growth and altered angiogenesis. Journal of pediatric surgery, 38 3, 308-14; discussion 3

Yokoi, Akiko; McCrudden, Kimberly W; Huang, Jianzhong; Kim, Eugene S; Soffer, Samuel Z; Frischer, Jason S; Serur, Anna; New, Tamara; Yuan, Jenny; Mansukhani, Mahesh; O'toole, Kathleen; Yamashiro, Darrell J; Kandel, Jessica J 2003. Human epidermal growth factor receptor signaling contributes to tumor growth via angiogenesis in her2/neu-expressing experimental Wilms' tumor. Journal of pediatric surgery, 38 11, 1569-73

Kim, Eugene S; Serur, Anna; Huang, Jianzhong; Manley, Christina A; McCrudden, Kimberly W; Frischer, Jason S; Soffer, Samuel Z; Ring, Laurence; New, Tamara; Zabski, Stephanie; Rudge, John S; Holash, Jocelyn; Yancopoulos, George D; Kandel, Jessica J; Yamashiro, Darrell J 2002. Potent VEGF blockade causes regression of coopted vessels in a model of neuroblastoma. Proceedings of the National Academy of Sciences of the United States of America, 99 17, 11399-404

Roayaie, Sasan; Frischer, Jason S; Emre, Sukru H; Fishbein, Thomas M; Sheiner, Patricia A; Sung, Max; Miller, Charles M; Schwartz, Myron E 2002. Long-term results with multimodal adjuvant therapy and liver transplantation for the treatment of hepatocellular carcinomas larger than 5 centimeters. Annals of surgery, 235 4, 533-9

Keswani, Sundeep G; Balaji, Swathi; Le, Louis D; Leung, Alice; Parvadia, Jignesh K; Frischer, Jason; Yamano, Seiichi; Taichman, Norton; Crombleholme, Timothy M . Role of salivary vascular endothelial growth factor (VEGF) in palatal mucosal wound healing. Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society, 21 4, 554-62

Yokoi, Akiko; McCrudden, Kimberly W; Huang, Jianzhong; Kim, Eugene S; Soffer, Samuel Z; Frischer, Jason S; Serur, Anna; New, Tamara; Yuan, Jenny; Mansukhani, Mahesh; O'Toole, Kathleen; Yamashiro, Darrell J; Kandel, Jessica J . Blockade of her2/neu decreases VEGF expression but does not alter HIF-1 distribution in experimental Wilms tumor. Oncology reports, 10 5, 1271-4