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Department of

Psychiatry and Behavioral Neuroscience

Stephen Benoit, PhD, MA, LPC

Associate Professor of Psychiatry and Behavioral Neuroscience, Director of Continuing Medical Education

Contact Information
  • Stetson Building
  • 260 Stetson Street
  • Cincinnati, Ohio 45219
  • Office 513-558-7700
  • Email stephen.benoit@uc.edu

Peer Reviewed Publications

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Ivezaj, V; Stoeckel, L E; Avena, N M; Benoit, S C; Conason, A; Davis, J F; Gearhardt, A N; Goldman, R; Mitchell, J E; Ochner, C N; Saules, K K; Steffen, K J; Stice, E; Sogg, S 2017. Obesity and addiction: can a complication of surgery help us understand the connection? Obesity reviews : an official journal of the International Association for the Study of Obesity, ,

Smith, Brittany L; Lyons, Carey E; Correa, Fernanda Guilhaume; Benoit, Stephen C; Myers, Brent; Solomon, Matia B; Herman, James P 2017. Behavioral and physiological consequences of enrichment loss in rats. Psychoneuroendocrinology, 77 , 37-46

Sirohi, Sunil; Schurdak, Jennifer D; Seeley, Randy J; Benoit, Stephen C; Davis, Jon F 2016. Central & peripheral glucagon-like peptide-1 receptor signaling differentially regulate addictive behaviors. Physiology & behavior, 161 , 140-4

Tracy, Andrea L; Schurdak, Jennifer D; Chambers, James B; Benoit, Stephen C 2016. Aversion learning can reduce meal size without taste avoidance in rats. Obesity (Silver Spring, Md.), 24 3, 606-14

Inge, Thomas H; Prigeon, Ronald L; Elder, Deborah A; Jenkins, Todd M; Cohen, Robert M; Xanthakos, Stavra A; Benoit, Stephen C; Dolan, Lawrence M; Daniels, Stephen R; D'Alessio, David A 2015. Insulin Sensitivity and ?-Cell Function Improve after Gastric Bypass in Severely Obese Adolescents. The Journal of pediatrics, 167 5, 1042-8.e1

Jury, Nicholas J; McCormick, Betsy A; Horseman, Nelson D; Benoit, Stephen C; Gregerson, Karen A 2015. Enhanced responsiveness to selective serotonin reuptake inhibitors during lactation. PloS one, 10 2, e0117339

Müller, T D; Nogueiras, R; Andermann, M L; Andrews, Z B; Anker, S D; Argente, J; Batterham, R L; Benoit, S C; Bowers, C Y; Broglio, F; Casanueva, F F; D'Alessio, D; Depoortere, I; Geliebter, A; Ghigo, E; Cole, P A; Cowley, M; Cummings, D E; Dagher, A; Diano, S; Dickson, S L; Diéguez, C; Granata, R; Grill, H J; Grove, K; Habegger, K M; Heppner, K; Heiman, M L; Holsen, L; Holst, B; Inui, A; Jansson, J O; Kirchner, H; Korbonits, M; Laferrère, B; LeRoux, C W; Lopez, M; Morin, S; Nakazato, M; Nass, R; Perez-Tilve, D; Pfluger, P T; Schwartz, T W; Seeley, R J; Sleeman, M; Sun, Y; Sussel, L; Tong, J; Thorner, M O; van der Lely, A J; van der Ploeg, L H T; Zigman, J M; Kojima, M; Kangawa, K; Smith, R G; Horvath, T; Tschöp, M H 2015. Ghrelin. Molecular metabolism, 4 6, 437-60

Benoit, Stephen C; Hunter, Tina D; Francis, Diane M; De La Cruz-Munoz, Nestor 2014. Use of Bariatric Outcomes Longitudinal Database (BOLD) to Study Variability in Patient Success After Bariatric Surgery. Obesity surgery, ,

Grayson, Bernadette E; Hakala-Finch, Andrew P; Kekulawala, Melani; Laub, Holly; Egan, Ann E; Ressler, Ilana B; Woods, Stephen C; Herman, James P; Seeley, Randy J; Benoit, Stephen C; Ulrich-Lai, Yvonne M 2014. Weight loss by calorie restriction versus bariatric surgery differentially regulates the hypothalamo-pituitary-adrenocortical axis in male rats. Stress (Amsterdam, Netherlands), 17 6, 484-93

Habegger, Kirk M; Heppner, Kristy M; Amburgy, Sarah E; Ottaway, Nickki; Holland, Jenna; Raver, Christine; Bartley, Erin; Müller, Timo D; Pfluger, Paul T; Berger, Jose; Toure, Mouhamadoul; Benoit, Stephen C; Dimarchi, Richard D; Perez-Tilve, Diego; D'Alessio, David A; Seeley, Randy J; Tschöp, Matthias H 2014. GLP-1R Responsiveness Predicts Individual Gastric Bypass Efficacy on Glucose Tolerance in Rats. Diabetes, 63 2, 505-13

Picard, Alexandre; Rouch, Claude; Kassis, Nadim; Moullé, Valentine S; Croizier, Sophie; Denis, Raphaël G; Castel, Julien; Coant, Nicolas; Davis, Kathryn; Clegg, Deborah J; Benoit, Stephen C; Prévot, Vincent; Bouret, Sébastien; Luquet, Serge; Le Stunff, Hervé; Cruciani-Guglielmacci, Céline; Magnan, Christophe 2014. Hippocampal lipoprotein lipase regulates energy balance in rodents. Molecular metabolism, 3 2, 167-76

Tong, Jenny; Davis, Harold W; Summer, Suzanne; Benoit, Stephen C; Haque, Ahrar; Bidlingmaier, Martin; Tschöp, Matthias H; D'Alessio, David 2014. Acute Administration of Unacylated Ghrelin Has No Effect on Basal or Stimulated Insulin Secretion in Healthy Humans. Diabetes, ,

Davis, Jon F; Benoit, Stephen C 2013. Response to Hajnal et al. Obesity surgery, 23 8, 1318

Davis, Jon F; Tracy, Andrea L; Schurdak, Jennifer D; Magrisso, Irwin J; Grayson, Bernadette E; Seeley, Randy J; Benoit, Stephen C 2013. Roux en Y gastric bypass increases ethanol intake in the rat. Obesity surgery, 23 7, 920-30

Figlewicz, Dianne P; Jay, Jennifer L; Acheson, Molly A; Magrisso, Irwin J; West, Constance H; Zavosh, Aryana; Benoit, Stephen C; Davis, Jon F 2013. Moderate high fat diet increases sucrose self-administration in young rats. Appetite, 61 1, 19-29

Grayson, B E; Fitzgerald, M F; Hakala-Finch, A P; Ferris, V M; Begg, D P; Tong, J; Woods, S C; Seeley, R J; Davidson, T L; Benoit, S C 2013. Improvements in hippocampal-dependent memory and microglial infiltration with calorie restriction and gastric bypass surgery, but not with vertical sleeve gastrectomy. International journal of obesity (2005), ,

Isom, Amanda M; Gudelsky, Gary A; Benoit, Stephen C; Richtand, Neil M 2013. Antipsychotic medications, glutamate, and cell death: a hidden, but common medication side effect? Medical hypotheses, 80 3, 252-8

Wilson-Pérez, H E; Chambers, A P; Sandoval, D A; Stefater, M A; Woods, S C; Benoit, S C; Seeley, R J 2013. The effect of vertical sleeve gastrectomy on food choice in rats. International journal of obesity (2005), 37 2, 288-95

Castañeda, Tamara R; Abplanalp, William; Um, Sung Hee; Pfluger, Paul T; Schrott, Brigitte; Brown, Kimberly; Grant, Erin; Carnevalli, Larissa; Benoit, Stephen C; Morgan, Donald A; Gilham, Dean; Hui, David Y; Rahmouni, Kamal; Thomas, George; Kozma, Sara C; Clegg, Deborah J; Tschöp, Matthias H 2012. Metabolic control by S6 kinases depends on dietary lipids. PloS one, 7 3, e32631

Choi, D L; Davis, J F; Magrisso, I J; Fitzgerald, M E; Lipton, J W; Benoit, S C 2012. Orexin signaling in the paraventricular thalamic nucleus modulates mesolimbic dopamine and hedonic feeding in the rat. Neuroscience, 210 , 243-8

Davis, J F; Perello, M; Choi, D L; Magrisso, I J; Kirchner, H; Pfluger, P T; Tschoep, M; Zigman, J M; Benoit, S C 2012. GOAT induced ghrelin acylation regulates hedonic feeding. Hormones and behavior, 62 5, 598-604

Davis, Jon F; Schurdak, Jennifer D; Magrisso, Irwin J; Mul, Joram D; Grayson, Bernadette E; Pfluger, Paul T; Tschöp, Mathias H; Seeley, Randy J; Benoit, Stephen C 2012. Gastric bypass surgery attenuates ethanol consumption in ethanol-preferring rats. Biological psychiatry, 72 5, 354-60

Kurosawa, Yuko; Degrauw, Ton J; Lindquist, Diana M; Blanco, Victor M; Pyne-Geithman, Gail J; Daikoku, Takiko; Chambers, James B; Benoit, Stephen C; Clark, Joseph F 2012. Cyclocreatine treatment improves cognition in mice with creatine transporter deficiency. The Journal of clinical investigation, 122 8, 2837-46

McNamara, Robert K; Magrisso, I Jack; Hofacer, Rylon; Jandacek, Ronald; Rider, Therese; Tso, Patrick; Benoit, Stephen C 2012. Omega-3 fatty acid deficiency augments risperidone-induced hepatic steatosis in rats: positive association with stearoyl-CoA desaturase. Pharmacological research : the official journal of the Italian Pharmacological Society, 66 4, 283-91

Yi, Chun-Xia; Heppner, Kristy M; Kirchner, Henriette; Tong, Jenny; Bielohuby, Maximillian; Gaylinn, Bruce D; Müller, Timo D; Bartley, Erin; Davis, Harold W; Zhao, Yongmei; Joseph, Anupama; Kruthaupt, Traci; Ottaway, Nickki; Kabra, Dhiraj; Habegger, Kirk M; Benoit, Stephen C; Bidlingmaier, Martin; Thorner, Michael O; Perez-Tilve, Diego; Tschöp, Matthias H; Pfluger, Paul T 2012. The GOAT-ghrelin system is not essential for hypoglycemia prevention during prolonged calorie restriction. PloS one, 7 2, e32100

Clegg, Deborah J; Gotoh, Koro; Kemp, Christopher; Wortman, Matthew D; Benoit, Stephen C; Brown, Lynda M; D'Alessio, David; Tso, Patrick; Seeley, Randy J; Woods, Stephen C 2011. Consumption of a high-fat diet induces central insulin resistance independent of adiposity. Physiology & behavior, 103 1, 10-6

Davis, Jon F; Choi, Derrick L; Clegg, Deborah J; Benoit, Stephen C 2011. Signaling through the ghrelin receptor modulates hippocampal function and meal anticipation in mice. Physiology & behavior, 103 1, 39-43

Davis, Jon F; Choi, Derrick L; Schurdak, Jennifer D; Fitzgerald, Maureen F; Clegg, Deborah J; Lipton, Jack W; Figlewicz, Dianne P; Benoit, Stephen C 2011. Leptin regulates energy balance and motivation through action at distinct neural circuits. Biological psychiatry, 69 7, 668-74

Davis, Jon F; Choi, Derrick L; Shurdak, Jennifer D; Krause, Eric G; Fitzgerald, Maureen F; Lipton, Jack W; Sakai, Randall R; Benoit, Stephen C 2011. Central melanocortins modulate mesocorticolimbic activity and food seeking behavior in the rat. Physiology & behavior, 102 5, 491-5

Hofacer, Rylon; Jack Magrisso, I; Jandacek, Ronald; Rider, Therese; Tso, Patrick; Benoit, Stephen C; McNamara, Robert K 2011. Omega-3 fatty acid deficiency increases stearoyl-CoA desaturase expression and activity indices in rat liver: Positive association with non-fasting plasma triglyceride levels. Prostaglandins, leukotrienes, and essential fatty acids, ,

Hofacer, Rylon; Jandacek, Ronald; Rider, Therese; Tso, Patrick; Magrisso, I Jack; Benoit, Stephen C; McNamara, Robert K 2011. Omega-3 fatty acid deficiency selectively up-regulates delta6-desaturase expression and activity indices in rat liver: prevention by normalization of omega-3 fatty acid status. Nutrition research (New York, N.Y.), 31 9, 715-22

Irani, Boman G; Xiang, Zhimin; Yarandi, Hossein N; Holder, Jerry R; Moore, Marcus C; Bauzo, Rayna M; Proneth, Bettina; Shaw, Amanda M; Millard, William J; Chambers, James B; Benoit, Stephen C; Clegg, Deborah J; Haskell-Luevano, Carrie 2011. Implication of the melanocortin-3 receptor in the regulation of food intake. European journal of pharmacology, 660 1, 80-7

Krawczewski Carhuatanta, Kimberly A; Demuro, Giovanna; Tschöp, Matthias H; Pfluger, Paul T; Benoit, Stephen C; Obici, Silvana 2011. Voluntary exercise improves high-fat diet-induced leptin resistance independent of adiposity. Endocrinology, 152 7, 2655-64

Summer, Suzanne S; Brehm, Bonnie J; Benoit, Stephen C; D'Alessio, David A 2011. Adiponectin changes in relation to the macronutrient composition of a weight-loss diet. Obesity (Silver Spring, Md.), 19 11, 2198-204

Benoit, Stephen C; Davis, Jon F; Davidson, T L 2010. Learned and cognitive controls of food intake. Brain research, 1350 , 71-6

Choi, D L; Davis, J F; Fitzgerald, M E; Benoit, S C 2010. The role of orexin-A in food motivation, reward-based feeding behavior and food-induced neuronal activation in rats. Neuroscience, 167 1, 11-20

Davidson, Terry L; Kanoski, Scott E; Chan, Kinho; Clegg, Deborah J; Benoit, Stephen C; Jarrard, Leonard E 2010. Hippocampal lesions impair retention of discriminative responding based on energy state cues. Behavioral neuroscience, 124 1, 97-105

Davis, Jon F; Choi, Derrick L; Benoit, Stephen C 2010. Insulin, leptin and reward. Trends in endocrinology and metabolism: TEM, 21 2, 68-74

Krikorian, Robert; Shidler, Marcelle D; Dangelo, Krista; Couch, Sarah C; Benoit, Stephen C; Clegg, Deborah J 2010. Dietary ketosis enhances memory in mild cognitive impairment. Neurobiology of aging, ,

Perez-Tilve, Diego; Hofmann, Susanna M; Basford, Joshua; Nogueiras, Ruben; Pfluger, Paul T; Patterson, James T; Grant, Erin; Wilson-Perez, Hilary E; Granholm, Norman A; Arnold, Myrtha; Trevaskis, James L; Butler, Andrew A; Davidson, William S; Woods, Stephen C; Benoit, Stephen C; Sleeman, Mark W; DiMarchi, Richard D; Hui, David Y; Tschöp, Matthias H 2010. Melanocortin signaling in the CNS directly regulates circulating cholesterol. Nature neuroscience, 13 7, 877-82

Zheng, Q; Zhu, J; Shanabrough, M; Borok, E; Benoit, S C; Horvath, T L; Clegg, D J; Reizes, O 2010. Enhanced anorexigenic signaling in lean obesity resistant syndecan-3 null mice. Neuroscience, 171 4, 1032-40

Benoit, Stephen C; Kemp, Christopher J; Elias, Carol F; Abplanalp, William; Herman, James P; Migrenne, Stephanie; Lefevre, Anne-Laure; Cruciani-Guglielmacci, Céline; Magnan, Christophe; Yu, Fang; Niswender, Kevin; Irani, Boman G; Holland, William L; Clegg, Deborah J 2009. Palmitic acid mediates hypothalamic insulin resistance by altering PKC-theta subcellular localization in rodents. The Journal of clinical investigation, 119 9, 2577-89

Davidson, Terry L; Chan, Kinho; Jarrard, Leonard E; Kanoski, Scott E; Clegg, Deborah J; Benoit, Stephen C 2009. Contributions of the hippocampus and medial prefrontal cortex to energy and body weight regulation. Hippocampus, 19 3, 235-52

Davis, J F; Krause, E G; Melhorn, S J; Sakai, R R; Benoit, S C 2009. Dominant rats are natural risk takers and display increased motivation for food reward. Neuroscience, 162 1, 23-30

Figlewicz, Dianne P; Benoit, Stephen C 2009. Insulin, leptin, and food reward: update 2008. American journal of physiology. Regulatory, integrative and comparative physiology, 296 1, R9-R19

Thaler, Joshua P; Choi, Sun Ju; Sajan, Mini P; Ogimoto, Kayoko; Nguyen, Hong T; Matsen, Miles; Benoit, Stephen C; Wisse, Brent E; Farese, Robert V; Schwartz, Michael W 2009. Atypical protein kinase C activity in the hypothalamus is required for lipopolysaccharide-mediated sickness responses. Endocrinology, 150 12, 5362-72

Thompson, Valerie B; Heiman, Justin; Chambers, James B; Benoit, Stephen C; Buesing, William R; Norman, Mantana K; Norman, Andrew B; Lipton, Jack W 2009. Long-term behavioral consequences of prenatal MDMA exposure. Physiology & behavior, 96 4-5, 593-601

Benoit, Stephen C; Tracy, Andrea L 2008. Behavioral controls of food intake. Peptides, 29 1, 139-47

Benoit, Stephen C; Tracy, Andrea L; Davis, Jon F; Choi, Derrick; Clegg, Deborah J 2008. Novel functions of orexigenic hypothalamic peptides: from genes to behavior. Nutrition (Burbank, Los Angeles County, Calif.), 24 9, 843-7

Davis, Jon F; Tracy, Andrea L; Schurdak, Jennifer D; Tschöp, Matthias H; Lipton, Jack W; Clegg, Deborah J; Benoit, Stephen C 2008. Exposure to elevated levels of dietary fat attenuates psychostimulant reward and mesolimbic dopamine turnover in the rat. Behavioral neuroscience, 122 6, 1257-63

Eric Hu, X; Wos, John A; Dowty, Martin E; Suchanek, Paula M; Ji, Wei; Chambers, James B; Benoit, Stephen C; Clegg, Deborah J; Reizes, Ofer 2008. Small-molecule melanin-concentrating hormone-1 receptor antagonists require brain penetration for inhibition of food intake and reduction in body weight. The Journal of pharmacology and experimental therapeutics, 324 1, 206-13

Kemp, Christopher J; D'Alessio, David A; Scott, Robert O; Kelm, Gary R; Meller, Stephen T; Barrera, Jason G; Seeley, Randy J; Clegg, Deborah J; Benoit, Stephen C 2008. Voluntary consumption of ethyl oleate reduces food intake and body weight in rats. Physiology & behavior, 93 4-5, 912-8

Krause, Eric G; Melhorn, Susan J; Davis, Jon F; Scott, Karen A; Ma, Li Y; de Kloet, Annette D; Benoit, Stephen C; Woods, Stephen C; Sakai, Randall R 2008. Angiotensin type 1 receptors in the subfornical organ mediate the drinking and hypothalamic-pituitary-adrenal response to systemic isoproterenol. Endocrinology, 149 12, 6416-24

Lo, Chun-Min; Samuelson, Linda C; Chambers, James Brad; King, Alexandra; Heiman, Justin; Jandacek, Ronald J; Sakai, Randall R; Benoit, Stephen C; Raybould, Helen E; Woods, Stephen C; Tso, Patrick 2008. Characterization of mice lacking the gene for cholecystokinin. American journal of physiology. Regulatory, integrative and comparative physiology, 294 3, R803-10

Nogueiras, Ruben; López, Miguel; Lage, Ricardo; Perez-Tilve, Diego; Pfluger, Paul; Mendieta-Zerón, Hugo; Sakkou, Maria; Wiedmer, Petra; Benoit, Stephen C; Datta, Rakesh; Dong, Jesse Z; Culler, Michael; Sleeman, Mark; Vidal-Puig, Antonio; Horvath, Tamas; Treier, Mathias; Diéguez, Carlos; Tschöp, Matthias H 2008. Bsx, a novel hypothalamic factor linking feeding with locomotor activity, is regulated by energy availability. Endocrinology, 149 6, 3009-15

Pfluger, Paul T; Kirchner, Henriette; Günnel, Susanne; Schrott, Brigitte; Perez-Tilve, Diego; Fu, Sheng; Benoit, Stephen C; Horvath, Tamas; Joost, Hans-Georg; Wortley, Katherine E; Sleeman, Mark W; Tschöp, Matthias H 2008. Simultaneous deletion of ghrelin and its receptor increases motor activity and energy expenditure. American journal of physiology. Gastrointestinal and liver physiology, 294 3, G610-8

Reed, Jacquelyn A; Benoit, Stephen C; Pfluger, Paul T; Tschöp, Matthias H; D'Alessio, David A; Seeley, Randy J 2008. Mice with chronically increased circulating ghrelin develop age-related glucose intolerance. American journal of physiology. Endocrinology and metabolism, 294 4, E752-60

Reizes, Ofer; Benoit, Stephen C; Clegg, Deborah J 2008. The role of syndecans in the regulation of body weight and synaptic plasticity. The international journal of biochemistry & cell biology, 40 1, 28-45

Tracy, Andrea L; Clegg, Deborah J; Johnson, Jeffrey D; Davidson, T L; Benoit, Stephen C 2008. The melanocortin antagonist AgRP (83-132) increases appetitive responding for a fat, but not a carbohydrate, reinforcer. Pharmacology, biochemistry, and behavior, 89 3, 263-71

Brown, Lynda M; Benoit, Stephen C; Woods, Stephen C; Clegg, Deborah J 2007. Intraventricular (i3vt) ghrelin increases food intake in fatty Zucker rats. Peptides, 28 3, 612-6

Clegg, Deborah J; Brown, Lynda M; Zigman, Jeffrey M; Kemp, Christopher J; Strader, April D; Benoit, Stephen C; Woods, Stephen C; Mangiaracina, Michela; Geary, Nori 2007. Estradiol-dependent decrease in the orexigenic potency of ghrelin in female rats. Diabetes, 56 4, 1051-8

Davidson, Terry L; Kanoski, Scott E; Schier, Lindsey A; Clegg, Deborah J; Benoit, Stephen C 2007. A potential role for the hippocampus in energy intake and body weight regulation. Current opinion in pharmacology, 7 6, 613-6

Davis, Jon F; Melhorn, Susan J; Shurdak, Jennifer D; Heiman, Justin U; Tschöp, Matthias H; Clegg, Deborah J; Benoit, Stephen C 2007. Comparison of hydrogenated vegetable shortening and nutritionally complete high-fat diet on limited access-binge behavior in rats. Physiology & behavior, 92 5, 924-30

Nogueiras, Ruben; Wiedmer, Petra; Perez-Tilve, Diego; Veyrat-Durebex, Christelle; Keogh, Julia M; Sutton, Gregory M; Pfluger, Paul T; Castaneda, Tamara R; Neschen, Susanne; Hofmann, Susanna M; Howles, Philip N; Morgan, Donald A; Benoit, Stephen C; Szanto, Ildiko; Schrott, Brigitte; Schürmann, Annette; Joost, Hans-Georg; Hammond, Craig; Hui, David Y; Woods, Stephen C; Rahmouni, Kamal; Butler, Andrew A; Farooqi, I Sadaf; O'Rahilly, Stephen; Rohner-Jeanrenaud, Françoise; Tschöp, Matthias H 2007. The central melanocortin system directly controls peripheral lipid metabolism. The Journal of clinical investigation, 117 11, 3475-88

Pfluger, P T; Kampe, J; Castaneda, T R; Vahl, T; D'Alessio, D A; Kruthaupt, T; Benoit, S C; Cuntz, U; Rochlitz, H J; Moehlig, M; Pfeiffer, A F H; Koebnick, C; Weickert, M O; Otto, B; Spranger, J; Tschöp, M H 2007. Effect of human body weight changes on circulating levels of peptide YY and peptide YY3-36. The Journal of clinical endocrinology and metabolism, 92 2, 583-8

Brown, Lynda M; Clegg, Deborah J; Benoit, Stephen C; Woods, Stephen C 2006. Intraventricular insulin and leptin reduce food intake and body weight in C57BL/6J mice. Physiology & behavior, 89 5, 687-91

Clegg, Deborah J; Brown, Lynda M; Woods, Stephen C; Benoit, Stephen C 2006. Gonadal hormones determine sensitivity to central leptin and insulin. Diabetes, 55 4, 978-87

Davis, Jon F; McQuade, John-Andrews M; Drazen, Deborah L; Woods, Stephen C; Seeley, Randy J; Benoit, Stephen C 2006. Role for dopamine-3 receptor in the hyperphagia of an unanticipated high-fat meal in rats. Pharmacology, biochemistry, and behavior, 85 1, 190-7

Diano, Sabrina; Farr, Susan A; Benoit, Stephen C; McNay, Ewan C; da Silva, Ivaldo; Horvath, Balazs; Gaskin, F Spencer; Nonaka, Naoko; Jaeger, Laura B; Banks, William A; Morley, John E; Pinto, Shirly; Sherwin, Robert S; Xu, Lin; Yamada, Kelvin A; Sleeman, Mark W; Tschöp, Matthias H; Horvath, Tamas L 2006. Ghrelin controls hippocampal spine synapse density and memory performance. Nature neuroscience, 9 3, 381-8

Duncan, Elizabeth A; Rider, Therese R; Jandacek, Ronald J; Clegg, Deborah J; Benoit, Stephen C; Tso, Patrick; Woods, Stephen C 2006. The regulation of alcohol intake by melanin-concentrating hormone in rats. Pharmacology, biochemistry, and behavior, 85 4, 728-35

Gotoh, Koro; Liu, Min; Benoit, Stephen C; Clegg, Deborah J; Davidson, W Sean; D'Alessio, David; Seeley, Randy J; Tso, Patrick; Woods, Stephen C 2006. Apolipoprotein A-IV interacts synergistically with melanocortins to reduce food intake. American journal of physiology. Regulatory, integrative and comparative physiology, 290 1, R202-7

Perez-Tilve, Diego; Nogueiras, Ruben; Mallo, Federico; Benoit, Stephen C; Tschoep, Matthias 2006. Gut hormones ghrelin, PYY, and GLP-1 in the regulation of energy balance [corrected] and metabolism. Endocrine, 29 1, 61-71

Reizes, Ofer; Clegg, Deborah J; Strader, April D; Benoit, Stephen C 2006. A role for syndecan-3 in the melanocortin regulation of energy balance. Peptides, 27 2, 274-80

Sanna, Bastiano; Brandt, Eric B; Kaiser, Robert A; Pfluger, Paul; Witt, Sandy A; Kimball, Thomas R; van Rooij, Eva; De Windt, Leon J; Rothenberg, Marc E; Tschop, Matthias H; Benoit, Stephen C; Molkentin, Jeffery D 2006. Modulatory calcineurin-interacting proteins 1 and 2 function as calcineurin facilitators in vivo. Proceedings of the National Academy of Sciences of the United States of America, 103 19, 7327-32

Benoit, Stephen C; Clegg, Deborah J; Woods, Stephen C; Seeley, Randy J 2005. The role of previous exposure in the appetitive and consummatory effects of orexigenic neuropeptides. Peptides, 26 5, 751-7

Benoit, Stephen C; Tschöp, Matthias H 2005. PYY3-36 "monkeys around" with energy balance. American journal of physiology. Regulatory, integrative and comparative physiology, 288 2, R358-9

Boggiano, M M; Chandler, P C; Oswald, K D; Rodgers, R J; Blundell, J E; Ishii, Y; Beattie, A H; Holch, P; Allison, D B; Schindler, M; Arndt, K; Rudolf, K; Mark, M; Schoelch, C; Joost, H G; Klaus, S; Thöne-Reineke, C; Benoit, S C; Seeley, R J; Beck-Sickinger, A G; Koglin, N; Raun, K; Madsen, K; Wulff, B S; Stidsen, C E; Birringer, M; Kreuzer, O J; Deng, X Y; Whitcomb, D C; Halem, H; Taylor, J; Dong, J; Datta, R; Culler, M; Ortmann, S; Castañeda, T R; Tschöp, M 2005. PYY3-36 as an anti-obesity drug target. Obesity reviews : an official journal of the International Association for the Study of Obesity, 6 4, 307-22

Clegg, Deborah J; Benoit, Stephen C; Reed, Jacquelyn A; Woods, Stephen C; Dunn-Meynell, Ambrose; Levin, Barry E 2005. Reduced anorexic effects of insulin in obesity-prone rats fed a moderate-fat diet. American journal of physiology. Regulatory, integrative and comparative physiology, 288 4, R981-6

Davidson, T L; Kanoski, Scott E; Tracy, Andrea L; Walls, Elwood K; Clegg, Debbie; Benoit, Stephen C 2005. The interoceptive cue properties of ghrelin generalize to cues produced by food deprivation. Peptides, 26 9, 1602-10

Otto, Bärbel; Spranger, Jochen; Benoit, Stephen C; Clegg, Debbie J; Tschöp, Matthias H 2005. The many faces of ghrelin: new perspectives for nutrition research? The British journal of nutrition, 93 6, 765-71

Benoit, Stephen C; Clegg, Deborah J; Seeley, Randy J; Woods, Stephen C 2004. Insulin and leptin as adiposity signals. Recent progress in hormone research, 59 , 267-85

Figlewicz, Dianne P; Bennett, Jennifer; Evans, Scott B; Kaiyala, Karl; Sipols, Alfred J; Benoit, Stephen C 2004. Intraventricular insulin and leptin reverse place preference conditioned with high-fat diet in rats. Behavioral neuroscience, 118 3, 479-87

McQuade, John-Andrews; Benoit, Stephen C; Xu, Ming; Woods, Stephen C; Seeley, Randy J 2004. High-fat diet induced adiposity in mice with targeted disruption of the dopamine-3 receptor gene. Behavioural brain research, 151 1-2, 313-9

Strader, April D; Reizes, Ofer; Woods, Stephen C; Benoit, Stephen C; Seeley, Randy J 2004. Mice lacking the syndecan-3 gene are resistant to diet-induced obesity. The Journal of clinical investigation, 114 9, 1354-60

Tschöp, M; Castañeda, T R; Joost, H G; Thöne-Reineke, C; Ortmann, S; Klaus, S; Hagan, M M; Chandler, P C; Oswald, K D; Benoit, S C; Seeley, R J; Kinzig, K P; Moran, T H; Beck-sickinger, A G; Koglin, N; Rodgers, R J; Blundell, J E; Ishii, Y; Beattie, A H; Holch, P; Allison, D B; Raun, K; Madsen, K; Wulff, B S; Stidsen, C E; Birringer, M; Kreuzer, O J; Schindler, M; Arndt, K; Rudolf, K; Mark, M; Deng, X Y; Whitcomb, D C; Halem, H; Taylor, J; Dong, J; Datta, R; Culler, M; Craney, S; Flora, D; Smiley, D; Heiman, M L; Withcomb, D C 2004. Physiology: does gut hormone PYY3-36 decrease food intake in rodents? Nature, 430 6996, 1 p following 165; d

Woods, Stephen C; Benoit, Stephen C; Clegg, Deborah J; Seeley, Randy J 2004. Clinical endocrinology and metabolism. Regulation of energy homeostasis by peripheral signals. Best practice & research. Clinical endocrinology & metabolism, 18 4, 497-515

Woods, Stephen C; D'Alessio, David A; Tso, Patrick; Rushing, Paul A; Clegg, Deborah J; Benoit, Stephen C; Gotoh, Koro; Liu, Min; Seeley, Randy J 2004. Consumption of a high-fat diet alters the homeostatic regulation of energy balance. Physiology & behavior, 83 4, 573-8

Benoit, S C; Sheldon, R J; Air, E L; Messerschmidt, P; Wilmer, K A; Hodge, K M B; Jones, M B; Eckstein, D M M; McOsker, C C; Woods, S C; Seeley, R J 2003. Assessment of the aversive consequences of acute and chronic administration of the melanocortin agonist, MTII. International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity, 27 5, 550-6

Benoit, Stephen C; Air, Ellen L; Wilmer, Kihmberly; Messerschmidt, Patrick; Hodge, Karen M B; Jones, Melissa B; Eckstein, Dawn M M; McOsker, Charles C; Seeley, Randy J; Woods, Stephen C; Sheldon, Russell J 2003. Two novel paradigms for the simultaneous assessment of conditioned taste aversion and food intake effects of anorexic agents. Physiology & behavior, 79 4-5, 761-6

Benoit, Stephen C; Clegg, Deborah J; Barrera, Jason G; Seeley, Randy J; Woods, Stephen C 2003. Learned meal initiation attenuates the anorexic effects of the melanocortin agonist MTII. Diabetes, 52 11, 2684-8

Benoit, Stephen C; McQuade, John-Andrews; Clegg, Deborah J; Xu, Ming; Rushing, Paul A; Woods, Stephen C; Seeley, Randy J 2003. Altered feeding responses in mice with targeted disruption of the dopamine-3 receptor gene. Behavioral neuroscience, 117 1, 46-54

Clegg, Deborah J; Air, Ellen L; Benoit, Stephen C; Sakai, Randall S; Seeley, Randy J; Woods, Stephen C 2003. Intraventricular melanin-concentrating hormone stimulates water intake independent of food intake. American journal of physiology. Regulatory, integrative and comparative physiology, 284 2, R494-9

Clegg, Deborah J; Benoit, Stephen C; Air, Ellen L; Jackman, Alana; Tso, Patrick; D'Alessio, David; Woods, Stephen C; Seeley, Randy J 2003. Increased dietary fat attenuates the anorexic effects of intracerebroventricular injections of MTII. Endocrinology, 144 7, 2941-6

Clegg, Deborah J; Riedy, Christine A; Smith, Kathleen A Blake; Benoit, Stephen C; Woods, Stephen C 2003. Differential sensitivity to central leptin and insulin in male and female rats. Diabetes, 52 3, 682-7

McQuade, John-Andrews M; Benoit, Stephen C; Woods, Stephen C; Seeley, Randy J 2003. 7-OH-DPAT selectively reduces intake of both chow and high fat diets in different food intake regimens. Pharmacology, biochemistry, and behavior, 76 3-4, 517-23

McQuade, John-Andrews; Xu, Ming; Woods, Stephen C; Seeley, Randy J; Benoit, Stephen C 2003. Ethanol consumption in mice with a targeted disruption of the dopamine-3 receptor gene. Addiction biology, 8 3, 295-303

Reizes, Ofer; Benoit, Stephen C; Strader, April D; Clegg, Deborah J; Akunuru, Shailaja; Seeley, Randy J 2003. Syndecan-3 modulates food intake by interacting with the melanocortin/AgRP pathway. Annals of the New York Academy of Sciences, 994 , 66-73

Air, Ellen L; Benoit, Stephen C; Blake Smith, Kathleen A; Clegg, Deborah J; Woods, Stephen C 2002. Acute third ventricular administration of insulin decreases food intake in two paradigms. Pharmacology, biochemistry, and behavior, 72 1-2, 423-9

Air, Ellen L; Benoit, Stephen C; Clegg, Deborah J; Seeley, Randy J; Woods, Stephen C 2002. Insulin and leptin combine additively to reduce food intake and body weight in rats. Endocrinology, 143 6, 2449-52

Air, Ellen L; Strowski, Mathias Z; Benoit, Stephen C; Conarello, Stacey L; Salituro, Gino M; Guan, Xiao-Ming; Liu, Kun; Woods, Stephen C; Zhang, Bei B 2002. Small molecule insulin mimetics reduce food intake and body weight and prevent development of obesity. Nature medicine, 8 2, 179-83

Benoit, Stephen C; Air, Ellen L; Coolen, Lique M; Strauss, Richelle; Jackman, Alana; Clegg, Deborah J; Seeley, Randy J; Woods, Stephen C 2002. The catabolic action of insulin in the brain is mediated by melanocortins. The Journal of neuroscience : the official journal of the Society for Neuroscience, 22 20, 9048-52

Clegg, Deborah J; Wortman, Matt D; Benoit, Stephen C; McOsker, Charles C; Seeley, Randy J 2002. Comparison of central and peripheral administration of C75 on food intake, body weight, and conditioned taste aversion. Diabetes, 51 11, 3196-201

Hagan, M M; Benoit, S C; Rushing, P A; Pritchard, L M; Woods, S C; Seeley, R J 2001. Immediate and prolonged patterns of Agouti-related peptide-(83--132)-induced c-Fos activation in hypothalamic and extrahypothalamic sites. Endocrinology, 142 3, 1050-6

Hagan, M M; Rushing, P A; Benoit, S C; Woods, S C; Seeley, R J 2001. Opioid receptor involvement in the effect of AgRP- (83-132) on food intake and food selection. American journal of physiology. Regulatory, integrative and comparative physiology, 280 3, R814-21

Benoit, S C; Schwartz, M W; Lachey, J L; Hagan, M M; Rushing, P A; Blake, K A; Yagaloff, K A; Kurylko, G; Franco, L; Danhoo, W; Seeley, R J 2000. A novel selective melanocortin-4 receptor agonist reduces food intake in rats and mice without producing aversive consequences. The Journal of neuroscience : the official journal of the Society for Neuroscience, 20 9, 3442-8

Benoit, S C; Thiele, T E; Heinrichs, S C; Rushing, P A; Blake, K A; Steeley, R J 2000. Comparison of central administration of corticotropin-releasing hormone and urocortin on food intake, conditioned taste aversion, and c-Fos expression. Peptides, 21 3, 345-51

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Benoit, S C; Davidson, T L 1996. Interoceptive sensory signals produced by 24-hr food deprivation, pharmacological glucoprivation, and lipoprivation. Behavioral neuroscience, 110 1, 168-80

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Benoit, S C; Tracy, A L; Air, E L; Kinzig, K; Seeley, R J; Davidson, T L . The role of the hypothalamic melanocortin system in behavioral appetitive processes. Pharmacology, biochemistry, and behavior, 69 3-4, 603-9

Cushing, Christopher C; Benoit, Stephen C; Peugh, James L; Reiter-Purtill, Jennifer; Inge, Thomas H; Zeller, Meg H . Longitudinal trends in hedonic hunger after Roux-en-Y gastric bypass in adolescents. Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery, 10 1, 125-30

Cushing, Christopher C; Peugh, James L; Brode, Cassie S; Inge, Thomas H; Benoit, Stephen C; Zeller, Meg H . Longitudinal trends in food cravings following Roux-en-Y gastric bypass in an adolescent sample. Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery, 11 1, 14-8

McNamara, Robert K; Ostrander, Michelle; Abplanalp, William; Richtand, Neil M; Benoit, Stephen C; Clegg, Debbie J . Modulation of phosphoinositide-protein kinase C signal transduction by omega-3 fatty acids: implications for the pathophysiology and treatment of recurrent neuropsychiatric illness. Prostaglandins, leukotrienes, and essential fatty acids, 75 4-5, 237-57