Prasad, Vikram; Lorenz, John N; Lasko, Valerie M; Nieman, Michelle L; Huang, Wei; Wang, Yigang; Wieczorek, David W; Shull, Gary E 2015. SERCA2 Haploinsufficiency in a Mouse Model of Darier Disease Causes a Selective Predisposition to Heart Failure. BioMed research international, 2015 , 251598
Prasad, Vikram; Lorenz, John N; Lasko, Valerie M; Nieman, Michelle L; Jiang, Min; Gao, Xu; Rubinstein, Jack; Wieczorek, David F; Shull, Gary E 2014. Ablation of plasma membrane Ca(2+)-ATPase isoform 4 prevents development of hypertrophy in a model of hypertrophic cardiomyopathy. Journal of molecular and cellular cardiology, 77 , 53-63
Rubinstein, Jack; Lasko, Valerie M; Koch, Sheryl E; Singh, Vivek P; Carreira, Vinicius; Robbins, Nathan; Patel, Amit R; Jiang, Min; Bidwell, Philip; Kranias, Evangelia G; Jones, W Keith; Lorenz, John N 2014. Novel role of transient receptor potential vanilloid 2 in the regulation of cardiac performance. American journal of physiology. Heart and circulatory physiology, 306 4, H574-84
Auger-Messier, Mannix; Accornero, Federica; Goonasekera, Sanjeewa A; Bueno, Orlando F; Lorenz, John N; van Berlo, Jop H; Willette, Robert N; Molkentin, Jeffery D 2013. Unrestrained p38 MAPK activation in Dusp1/4 double-null mice induces cardiomyopathy. Circulation research, 112 1, 48-56
Gupta, Manish K; Gulick, James; James, Jeanne; Osinska, Hanna; Lorenz, John N; Robbins, Jeffrey 2013. Functional dissection of myosin binding protein C phosphorylation. Journal of molecular and cellular cardiology, 64 , 39-50
Prasad, Vikram; Lorenz, John N; Lasko, Valerie M; Nieman, Michelle L; Al Moamen, Nabeel J; Shull, Gary E 2013. Loss of the AE3 Cl(-)/HCO(-) 3 exchanger in mice affects rate-dependent inotropy and stress-related AKT signaling in heart. Frontiers in physiology, 4 , 399
Prasad, Vikram; Lorenz, John N; Miller, Marian L; Vairamani, Kanimozhi; Nieman, Michelle L; Wang, Yigang; Shull, Gary E 2013. Loss of NHE1 activity leads to reduced oxidative stress in heart and mitigates high-fat diet-induced myocardial stress. Journal of molecular and cellular cardiology, 65 , 33-42
Rindler, Tara N; Lasko, Valerie M; Nieman, Michelle L; Okada, Motoi; Lorenz, John N; Lingrel, Jerry B 2013. Knockout of the Na,K-ATPase ?2-isoform in cardiac myocytes delays pressure overload-induced cardiac dysfunction. American journal of physiology. Heart and circulatory physiology, 304 8, H1147-58
Singh, Vivek P; Rubinstein, Jack; Arvanitis, Demetrios A; Ren, Xiaoping; Gao, Xiaoqian; Haghighi, Kobra; Gilbert, Mark; Iyer, Venkat R; Kim, Do Han; Cho, Chunghee; Jones, Keith; Lorenz, John N; Armstrong, Clara F; Wang, Hong-Sheng; Gyorke, Sandor; Kranias, Evangelia G 2013. Abnormal calcium cycling and cardiac arrhythmias associated with the human Ser96Ala genetic variant of histidine-rich calcium-binding protein. Journal of the American Heart Association, 2 5, e000460
Koch, Sheryl E; Gao, Xiaoqian; Haar, Lauren; Jiang, Min; Lasko, Valerie M; Robbins, Nathan; Cai, Wenfeng; Brokamp, Cole; Varma, Priyanka; Tranter, Michael; Liu, Yong; Ren, Xiaoping; Lorenz, John N; Wang, Hong-Sheng; Jones, W Keith; Rubinstein, Jack 2012. Probenecid: novel use as a non-injurious positive inotrope acting via cardiac TRPV2 stimulation. Journal of molecular and cellular cardiology, 53 1, 134-44
Lorenz, John N 2012. Micropuncture of the kidney: a primer on techniques. Comprehensive Physiology, 2 1, 621-37
Lorenz, John N; Oshiro, Naomi; Loreaux, Elizabeth L; Lingrel, Jerry B 2012. DOCA-salt hypertension does not require the ouabain-sensitive binding site of the ?2 Na,K-ATPase. American journal of hypertension, 25 4, 421-9
Lynch, Jeffrey M; Maillet, Marjorie; Vanhoutte, Davy; Schloemer, Aryn; Sargent, Michelle A; Blair, N Scott; Lynch, Kaari A; Okada, Tetsuya; Aronow, Bruce J; Osinska, Hanna; Prywes, Ron; Lorenz, John N; Mori, Kazutoshi; Lawler, Jack; Robbins, Jeffrey; Molkentin, Jeffery D 2012. A thrombospondin-dependent pathway for a protective ER stress response. Cell, 149 6, 1257-68
Accornero, Federica; van Berlo, Jop H; Benard, Matthew J; Lorenz, John N; Carmeliet, Peter; Molkentin, Jeffery D 2011. Placental growth factor regulates cardiac adaptation and hypertrophy through a paracrine mechanism. Circulation research, 109 3, 272-80
Al Moamen, Nabeel J; Prasad, Vikram; Bodi, Ilona; Miller, Marian L; Neiman, Michelle L; Lasko, Valerie M; Alper, Seth L; Wieczorek, David F; Lorenz, John N; Shull, Gary E 2011. Loss of the AE3 anion exchanger in a hypertrophic cardiomyopathy model causes rapid decompensation and heart failure. Journal of molecular and cellular cardiology, 50 1, 137-46
Kehat, Izhak; Davis, Jennifer; Tiburcy, Malte; Accornero, Federica; Saba-El-Leil, Marc K; Maillet, Marjorie; York, Allen J; Lorenz, John N; Zimmermann, Wolfram H; Meloche, Sylvain; Molkentin, Jeffery D 2011. Extracellular signal-regulated kinases 1 and 2 regulate the balance between eccentric and concentric cardiac growth. Circulation research, 108 2, 176-83
Lorenz, John N; Lasko, Valerie M; Nieman, Michelle L; Damhoff, Thomas; Prasad, Vikram; Beierwaltes, William H; Lingrel, Jerry B 2011. Renovascular hypertension using a modified two-kidney, one-clip approach in mice is not dependent on the ?1 or ?2 Na-K-ATPase ouabain-binding site. American journal of physiology. Renal physiology, 301 3, F615-21
Rindler, Tara N; Dostanic, Iva; Lasko, Valerie M; Nieman, Michelle L; Neumann, Jonathan C; Lorenz, John N; Lingrel, Jerry B 2011. Knockout of the Na,K-ATPase ??-isoform in the cardiovascular system does not alter basal blood pressure but prevents ACTH-induced hypertension. American journal of physiology. Heart and circulatory physiology, 301 4, H1396-404
Wansapura, Arshani N; Lasko, Valerie M; Lingrel, Jerry B; Lorenz, John N 2011. Mice expressing ouabain-sensitive ?1-Na,K-ATPase have increased susceptibility to pressure overload-induced cardiac hypertrophy. American journal of physiology. Heart and circulatory physiology, 300 1, H347-55
Bradford, Emily M; Miller, Marian L; Prasad, Vikram; Nieman, Michelle L; Gawenis, Lara R; Berryman, Mark; Lorenz, John N; Tso, Patrick; Shull, Gary E 2010. CLIC5 mutant mice are resistant to diet-induced obesity and exhibit gastric hemorrhaging and increased susceptibility to torpor. American journal of physiology. Regulatory, integrative and comparative physiology, 298 6, R1531-42
Maillet, Marjorie; Davis, Jennifer; Auger-Messier, Mannix; York, Allen; Osinska, Hanna; Piquereau, Jérôme; Lorenz, John N; Robbins, Jeffrey; Ventura-Clapier, Renée; Molkentin, Jeffery D 2010. Heart-specific deletion of CnB1 reveals multiple mechanisms whereby calcineurin regulates cardiac growth and function. The Journal of biological chemistry, 285 9, 6716-24
Nakayama, Hiroyuki; Bodi, Ilona; Maillet, Marjorie; DeSantiago, Jaime; Domeier, Timothy L; Mikoshiba, Katsuhiko; Lorenz, John N; Blatter, Lothar A; Bers, Donald M; Molkentin, Jeffery D 2010. The IP3 receptor regulates cardiac hypertrophy in response to select stimuli. Circulation research, 107 5, 659-66
Liu, Qinghang; Chen, Xiongwen; Macdonnell, Scott M; Kranias, Evangelia G; Lorenz, John N; Leitges, Michael; Houser, Steven R; Molkentin, Jeffery D 2009. Protein kinase C{alpha}, but not PKC{beta} or PKC{gamma}, regulates contractility and heart failure susceptibility: implications for ruboxistaurin as a novel therapeutic approach. Circulation research, 105 2, 194-200
Maloyan, Alina; Osinska, Hanna; Lammerding, Jan; Lee, Richard T; Cingolani, Oscar H; Kass, David A; Lorenz, John N; Robbins, Jeffrey 2009. Biochemical and mechanical dysfunction in a mouse model of desmin-related myopathy. Circulation research, 104 8, 1021-8
Sadayappan, Sakthivel; Gulick, James; Klevitsky, Raisa; Lorenz, John N; Sargent, Michelle; Molkentin, Jeffery D; Robbins, Jeffrey 2009. Cardiac myosin binding protein-C phosphorylation in a {beta}-myosin heavy chain background. Circulation, 119 9, 1253-62
Wansapura, Arshani N; Lasko, Valerie; Xie, Zijian; Fedorova, Olga V; Bagrov, Alexei Y; Lingrel, Jerry B; Lorenz, John N 2009. Marinobufagenin enhances cardiac contractility in mice with ouabain-sensitive alpha1 Na+-K+-ATPase. American journal of physiology. Heart and circulatory physiology, 296 6, H1833-9
Diwan, Abhinav; Wansapura, Janaka; Syed, Faisal M; Matkovich, Scot J; Lorenz, John N; Dorn, Gerald W 2008. Nix-mediated apoptosis links myocardial fibrosis, cardiac remodeling, and hypertrophy decompensation. Circulation, 117 3, 396-404
Loreaux, Elizabeth L; Kaul, Baksho; Lorenz, John N; Lingrel, Jerry B 2008. Ouabain-Sensitive alpha1 Na,K-ATPase enhances natriuretic response to saline load. Journal of the American Society of Nephrology : JASN, 19 10, 1947-54
Lorenz, John N; Loreaux, Elizabeth L; Dostanic-Larson, Iva; Lasko, Valerie; Schnetzer, J Renee; Paul, Richard J; Lingrel, Jerry B 2008. ACTH-induced hypertension is dependent on the ouabain-binding site of the alpha2-Na+-K+-ATPase subunit. American journal of physiology. Heart and circulatory physiology, 295 1, H273-80
Prasad, Vikram; Bodi, Ilona; Meyer, Jamie W; Wang, Yigang; Ashraf, Muhammad; Engle, Sandra J; Doetschman, Thomas; Sisco, Karena; Nieman, Michelle L; Miller, Marian L; Lorenz, John N; Shull, Gary E 2008. Impaired cardiac contractility in mice lacking both the AE3 Cl-/HCO3- exchanger and the NKCC1 Na+-K+-2Cl- cotransporter: effects on Ca2+ handling and protein phosphatases. The Journal of biological chemistry, 283 46, 31303-14
Sadayappan, Sakthivel; Finley, Natosha; Howarth, Jack W; Osinska, Hanna; Klevitsky, Raisa; Lorenz, John N; Rosevear, Paul R; Robbins, Jeffrey 2008. Role of the acidic N' region of cardiac troponin I in regulating myocardial function. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 22 4, 1246-57
Gawenis, Lara R; Bradford, Emily M; Prasad, Vikram; Lorenz, John N; Simpson, Janet E; Clarke, Lane L; Woo, Alison L; Grisham, Christina; Sanford, L Philip; Doetschman, Thomas; Miller, Marian L; Shull, Gary E 2007. Colonic anion secretory defects and metabolic acidosis in mice lacking the NBC1 Na+/HCO3- cotransporter. The Journal of biological chemistry, 282 12, 9042-52
Hambleton, Michael; York, Allen; Sargent, Michelle A; Kaiser, Robert A; Lorenz, John N; Robbins, Jeffrey; Molkentin, Jeffery D 2007. Inducible and myocyte-specific inhibition of PKCalpha enhances cardiac contractility and protects against infarction-induced heart failure. American journal of physiology. Heart and circulatory physiology, 293 6, H3768-71
Kawedia, Jitesh D; Nieman, Michelle L; Boivin, Gregory P; Melvin, James E; Kikuchi, Ken-Ichiro; Hand, Arthur R; Lorenz, John N; Menon, Anil G 2007. Interaction between transcellular and paracellular water transport pathways through Aquaporin 5 and the tight junction complex. Proceedings of the National Academy of Sciences of the United States of America, 104 9, 3621-6
Lorenz, John N; Arend, Lois J; Robitz, Rachel; Paul, Richard J; MacLennan, A John 2007. Vascular dysfunction in S1P2 sphingosine 1-phosphate receptor knockout mice. American journal of physiology. Regulatory, integrative and comparative physiology, 292 1, R440-6
Pritchard, Tracy J; Parvatiyar, Michelle; Bullard, Daniel P; Lynch, Ronald M; Lorenz, John N; Paul, Richard J 2007. Transgenic mice expressing Na+-K+-ATPase in smooth muscle decreases blood pressure. American journal of physiology. Heart and circulatory physiology, 293 2, H1172-82
Adhami, Faisal; Liao, Guanghong; Morozov, Yury M; Schloemer, Aryn; Schmithorst, Vincent J; Lorenz, John N; Dunn, R Scott; Vorhees, Charles V; Wills-Karp, Marsha; Degen, Jay L; Davis, Roger J; Mizushima, Noboru; Rakic, Pasko; Dardzinski, Bernard J; Holland, Scott K; Sharp, Frank R; Kuan, Chia-Yi 2006. Cerebral ischemia-hypoxia induces intravascular coagulation and autophagy. The American journal of pathology, 169 2, 566-83
Dostanic-Larson, Iva; Lorenz, John N; Van Huysse, James W; Neumann, Jon C; Moseley, Amy E; Lingrel, Jerry B 2006. Physiological role of the alpha1- and alpha2-isoforms of the Na+-K+-ATPase and biological significance of their cardiac glycoside binding site. American journal of physiology. Regulatory, integrative and comparative physiology, 290 3, R524-8
Elitsur, Noeet; Lorenz, John N; Hawkins, Jennifer A; Rudolph, Jeffrey A; Witte, David; Yang, Li E; McDonough, Alicia A; Cohen, Mitchell B 2006. The proximal convoluted tubule is a target for the uroguanylin-regulated natriuretic response. Journal of pediatric gastroenterology and nutrition, 43 Suppl 1 , S74-81
Lorenz, John N; Dostanic-Larson, Iva; Shull, Gary E; Lingrel, Jerry B 2006. Ouabain inhibits tubuloglomerular feedback in mutant mice with ouabain-sensitive alpha1 Na,K-ATPase. Journal of the American Society of Nephrology : JASN, 17 9, 2457-63
Sadayappan, Sakthivel; Osinska, Hanna; Klevitsky, Raisa; Lorenz, John N; Sargent, Michelle; Molkentin, Jeffrey D; Seidman, Christine E; Seidman, Jonathan G; Robbins, Jeffrey 2006. Cardiac myosin binding protein C phosphorylation is cardioprotective. Proceedings of the National Academy of Sciences of the United States of America, 103 45, 16918-23
Xu, Jian; Kimball, Thomas R; Lorenz, John N; Brown, David A; Bauskin, Asne R; Klevitsky, Raisa; Hewett, Timothy E; Breit, Samuel N; Molkentin, Jeffery D 2006. GDF15/MIC-1 functions as a protective and antihypertrophic factor released from the myocardium in association with SMAD protein activation. Circulation research, 98 3, 342-50
Dostanic, Iva; Paul, Richard J; Lorenz, John N; Theriault, Steven; Van Huysse, James W; Lingrel, Jerry B 2005. The alpha2-isoform of Na-K-ATPase mediates ouabain-induced hypertension in mice and increased vascular contractility in vitro. American journal of physiology. Heart and circulatory physiology, 288 2, H477-85
Dostanic-Larson, Iva; Van Huysse, James W; Lorenz, John N; Lingrel, Jerry B 2005. The highly conserved cardiac glycoside binding site of Na,K-ATPase plays a role in blood pressure regulation. Proceedings of the National Academy of Sciences of the United States of America, 102 44, 15845-50
Noonan, William T; Woo, Alison L; Nieman, Michelle L; Prasad, Vikram; Schultheis, Patrick J; Shull, Gary E; Lorenz, John N 2005. Blood pressure maintenance in NHE3-deficient mice with transgenic expression of NHE3 in small intestine. American journal of physiology. Regulatory, integrative and comparative physiology, 288 3, R685-91
Pathak, Anand; del Monte, Federica; Zhao, Wen; Schultz, Jo-El; Lorenz, John N; Bodi, Ilona; Weiser, Doug; Hahn, Harvey; Carr, Andrew N; Syed, Faisal; Mavila, Nirmala; Jha, Leena; Qian, Jiang; Marreez, Yehia; Chen, Guoli; McGraw, Dennis W; Heist, E Kevin; Guerrero, J Luis; DePaoli-Roach, Anna A; Hajjar, Roger J; Kranias, Evangelia G 2005. Enhancement of cardiac function and suppression of heart failure progression by inhibition of protein phosphatase 1. Circulation research, 96 7, 756-66
Sakthivel, Sadayappan; Finley, Natosha L; Rosevear, Paul R; Lorenz, John N; Gulick, James; Kim, Scott; VanBuren, Peter; Martin, Lisa A; Robbins, Jeffrey 2005. In vivo and in vitro analysis of cardiac troponin I phosphorylation. The Journal of biological chemistry, 280 1, 703-14
Wang, Zhaohui; Wang, Tong; Petrovic, Snezana; Tuo, Biguang; Riederer, Brigitte; Barone, Sharon; Lorenz, John N; Seidler, Ursula; Aronson, Peter S; Soleimani, Manoocher 2005. Renal and intestinal transport defects in Slc26a6-null mice. American journal of physiology. Cell physiology, 288 4, C957-65
Braz, Julian C; Gregory, Kimberly; Pathak, Anand; Zhao, Wen; Sahin, Bogachan; Klevitsky, Raisa; Kimball, Thomas F; Lorenz, John N; Nairn, Angus C; Liggett, Stephen B; Bodi, Ilona; Wang, Su; Schwartz, Arnold; Lakatta, Edward G; DePaoli-Roach, Anna A; Robbins, Jeffrey; Hewett, Timothy E; Bibb, James A; Westfall, Margaret V; Kranias, Evangelia G; Molkentin, Jeffery D 2004. PKC-alpha regulates cardiac contractility and propensity toward heart failure. Nature medicine, 10 3, 248-54
Dostanic, Iva; Schultz, Jo El J; Lorenz, John N; Lingrel, Jerry B 2004. The alpha 1 isoform of Na,K-ATPase regulates cardiac contractility and functionally interacts and co-localizes with the Na/Ca exchanger in heart. The Journal of biological chemistry, 279 52, 54053-61
Kumar, A; Crawford, K; Flick, R; Klevitsky, R; Lorenz, J N; Bove, K E; Robbins, J; Lessard, J L 2004. Transgenic overexpression of cardiac actin in the mouse heart suggests coregulation of cardiac, skeletal and vascular actin expression. Transgenic research, 13 6, 531-40
Quinlan, John G; Hahn, Harvey S; Wong, Brenda L; Lorenz, John N; Wenisch, Alexandra S; Levin, Linda S 2004. Evolution of the mdx mouse cardiomyopathy: physiological and morphological findings. Neuromuscular disorders : NMD, 14 8-9, 491-6
Dostanic, Iva; Lorenz, John N; Schultz, Jo El J; Grupp, Ingrid L; Neumann, Jonathan C; Wani, Maqsood A; Lingrel, Jerry B 2003. The alpha2 isoform of Na,K-ATPase mediates ouabain-induced cardiac inotropy in mice. The Journal of biological chemistry, 278 52, 53026-34
Ji, Yong; Li, Bailing; Reed, Thomas D; Lorenz, John N; Kaetzel, Marcia A; Dedman, John R 2003. Targeted inhibition of Ca2+/calmodulin-dependent protein kinase II in cardiac longitudinal sarcoplasmic reticulum results in decreased phospholamban phosphorylation at threonine 17. The Journal of biological chemistry, 278 27, 25063-71
Krenz, Maike; Sanbe, Atsushi; Bouyer-Dalloz, Florence; Gulick, James; Klevitsky, Raisa; Hewett, Timothy E; Osinska, Hanna E; Lorenz, John N; Brosseau, Christine; Federico, Andrea; Alpert, Norman R; Warshaw, David M; Perryman, M Benjamin; Helmke, Steve M; Robbins, Jeffrey 2003. Analysis of myosin heavy chain functionality in the heart. The Journal of biological chemistry, 278 19, 17466-74
Lorenz, John N; Nieman, Michelle; Sabo, Jenine; Sanford, L Philip; Hawkins, Jennifer A; Elitsur, Noeet; Gawenis, Lara R; Clarke, Lane L; Cohen, Mitchell B 2003. Uroguanylin knockout mice have increased blood pressure and impaired natriuretic response to enteral NaCl load. The Journal of clinical investigation, 112 8, 1244-54
Noonan, William T; Lorenz, John N 2003. Clearance studies in genetically altered mice. Methods in molecular medicine, 86 , 315-27
Noonan, William T; Qian, Jin; Stuart, William D; Clemens, Thomas L; Lorenz, John N 2003. Altered renal hemodynamics in mice overexpressing the parathyroid hormone (PTH)/PTH-related peptide type 1 receptor in smooth muscle. Endocrinology, 144 11, 4931-8
Shull, Gary E; Okunade, Gbolahan; Liu, Lynne H; Kozel, Peter; Periasamy, Muthu; Lorenz, John N; Prasad, Vikram 2003. Physiological functions of plasma membrane and intracellular Ca2+ pumps revealed by analysis of null mutants. Annals of the New York Academy of Sciences, 986 , 453-60
Woo, Alison L; Noonan, William T; Schultheis, Patrick J; Neumann, Jonathan C; Manning, Patrice A; Lorenz, John N; Shull, Gary E 2003. Renal function in NHE3-deficient mice with transgenic rescue of small intestinal absorptive defect. American journal of physiology. Renal physiology, 284 6, F1190-8
Bueno, Orlando F; Wilkins, Benjamin J; Tymitz, Kevin M; Glascock, Betty J; Kimball, Thomas F; Lorenz, John N; Molkentin, Jeffery D 2002. Impaired cardiac hypertrophic response in Calcineurin Abeta -deficient mice. Proceedings of the National Academy of Sciences of the United States of America, 99 7, 4586-91
Lorenz, John N 2002. A practical guide to evaluating cardiovascular, renal, and pulmonary function in mice. American journal of physiology. Regulatory, integrative and comparative physiology, 282 6, R1565-82
Lorenz, John N; Baird, Nancy R; Judd, Louise M; Noonan, William T; Andringa, Anastasia; Doetschman, Thomas; Manning, Patrice A; Liu, Lynne H; Miller, Marian L; Shull, Gary E 2002. Impaired renal NaCl absorption in mice lacking the ROMK potassium channel, a model for type II Bartter's syndrome. The Journal of biological chemistry, 277 40, 37871-80
Meyer, Jamie W; Flagella, Michael; Sutliff, Roy L; Lorenz, John N; Nieman, Michelle L; Weber, Craig S; Paul, Richard J; Shull, Gary E 2002. Decreased blood pressure and vascular smooth muscle tone in mice lacking basolateral Na(+)-K(+)-2Cl(-) cotransporter. American journal of physiology. Heart and circulatory physiology, 283 5, H1846-55
Pieples, Kathy; Arteaga, Grace; Solaro, R John; Grupp, Ingrid; Lorenz, John N; Boivin, Greg P; Jagatheesan, Ganapathy; Labitzke, Erin; DeTombe, Pieter P; Konhilas, John P; Irving, Thomas C; Wieczorek, David F 2002. Tropomyosin 3 expression leads to hypercontractility and attenuates myofilament length-dependent Ca(2+) activation. American journal of physiology. Heart and circulatory physiology, 283 4, H1344-53
Schmidt, Albrecht G; Zhai, Jing; Carr, Andrew N; Gerst, Mike J; Lorenz, John N; Pollesello, Piero; Annila, Arto; Hoit, Brian D; Kranias, Evangelia G 2002. Structural and functional implications of the phospholamban hinge domain: impaired SR Ca2+ uptake as a primary cause of heart failure. Cardiovascular research, 56 2, 248-59
Yussman, Martin G; Toyokawa, Tsuyoshi; Odley, Amy; Lynch, Roy A; Wu, Guangyu; Colbert, Melissa C; Aronow, Bruce J; Lorenz, John N; Dorn, Gerald W 2002. Mitochondrial death protein Nix is induced in cardiac hypertrophy and triggers apoptotic cardiomyopathy. Nature medicine, 8 7, 725-30
Dalton, T P; Kerzee, J K; Wang, B; Miller, M; Dieter, M Z; Lorenz, J N; Shertzer, H G; Nerbert, D W; Puga, A 2001. Dioxin exposure is an environmental risk factor for ischemic heart disease. Cardiovascular toxicology, 1 4, 285-98
Fortner, C N; Lorenz, J N; Paul, R J 2001. Chloride channel function is linked to epithelium-dependent airway relaxation. American journal of physiology. Lung cellular and molecular physiology, 280 2, L334-41
Krane, C M; Fortner, C N; Hand, A R; McGraw, D W; Lorenz, J N; Wert, S E; Towne, J E; Paul, R J; Whitsett, J A; Menon, A G 2001. Aquaporin 5-deficient mouse lungs are hyperresponsive to cholinergic stimulation. Proceedings of the National Academy of Sciences of the United States of America, 98 24, 14114-9
Ledoussal, C; Lorenz, J N; Nieman, M L; Soleimani, M; Schultheis, P J; Shull, G E 2001. Renal salt wasting in mice lacking NHE3 Na+/H+ exchanger but not in mice lacking NHE2. American journal of physiology. Renal physiology, 281 4, F718-27
Lorenz, J N 2001. Considerations for the evaluation of renal function in genetically engineered mice. Current opinion in nephrology and hypertension, 10 1, 65-9
Wang, X; Osinska, H; Dorn, G W; Nieman, M; Lorenz, J N; Gerdes, A M; Witt, S; Kimball, T; Gulick, J; Robbins, J 2001. Mouse model of desmin-related cardiomyopathy. Circulation, 103 19, 2402-7
Liggett, S B; Tepe, N M; Lorenz, J N; Canning, A M; Jantz, T D; Mitarai, S; Yatani, A; Dorn, G W 2000. Early and delayed consequences of beta(2)-adrenergic receptor overexpression in mouse hearts: critical role for expression level. Circulation, 101 14, 1707-14
Dorn, G W; Souroujon, M C; Liron, T; Chen, C H; Gray, M O; Zhou, H Z; Csukai, M; Wu, G; Lorenz, J N; Mochly-Rosen, D 1999. Sustained in vivo cardiac protection by a rationally designed peptide that causes epsilon protein kinase C translocation. Proceedings of the National Academy of Sciences of the United States of America, 96 22, 12798-803
Dorn, G W; Tepe, N M; Lorenz, J N; Koch, W J; Liggett, S B 1999. Low- and high-level transgenic expression of beta2-adrenergic receptors differentially affect cardiac hypertrophy and function in Galphaq-overexpressing mice. Proceedings of the National Academy of Sciences of the United States of America, 96 11, 6400-5
Flagella, M; Clarke, L L; Miller, M L; Erway, L C; Giannella, R A; Andringa, A; Gawenis, L R; Kramer, J; Duffy, J J; Doetschman, T; Lorenz, J N; Yamoah, E N; Cardell, E L; Shull, G E 1999. Mice lacking the basolateral Na-K-2Cl cotransporter have impaired epithelial chloride secretion and are profoundly deaf. The Journal of biological chemistry, 274 38, 26946-55
Lorenz, J N; Gruenstein, E 1999. A simple, nonradioactive method for evaluating single-nephron filtration rate using FITC-inulin. The American journal of physiology, 276 1 Pt 2, F172-7
Lorenz, J N; Schultheis, P J; Traynor, T; Shull, G E; Schnermann, J 1999. Micropuncture analysis of single-nephron function in NHE3-deficient mice. The American journal of physiology, 277 3 Pt 2, F447-53
Maeda, S; Sutliff, R L; Qian, J; Lorenz, J N; Wang, J; Tang, H; Nakayama, T; Weber, C; Witte, D; Strauch, A R; Paul, R J; Fagin, J A; Clemens, T L 1999. Targeted overexpression of parathyroid hormone-related protein (PTHrP) to vascular smooth muscle in transgenic mice lowers blood pressure and alters vascular contractility. Endocrinology, 140 4, 1815-25
Periasamy, M; Reed, T D; Liu, L H; Ji, Y; Loukianov, E; Paul, R J; Nieman, M L; Riddle, T; Duffy, J J; Doetschman, T; Lorenz, J N; Shull, G E 1999. Impaired cardiac performance in heterozygous mice with a null mutation in the sarco(endo)plasmic reticulum Ca2+-ATPase isoform 2 (SERCA2) gene. The Journal of biological chemistry, 274 4, 2556-62
Qian, J; Lorenz, J N; Maeda, S; Sutliff, R L; Weber, C; Nakayama, T; Colbert, M C; Paul, R J; Fagin, J A; Clemens, T L 1999. Reduced blood pressure and increased sensitivity of the vasculature to parathyroid hormone-related protein (PTHrP) in transgenic mice overexpressing the PTH/PTHrP receptor in vascular smooth muscle. Endocrinology, 140 4, 1826-33
Schultz, J E; Witt, S A; Nieman, M L; Reiser, P J; Engle, S J; Zhou, M; Pawlowski, S A; Lorenz, J N; Kimball, T R; Doetschman, T 1999. Fibroblast growth factor-2 mediates pressure-induced hypertrophic response. The Journal of clinical investigation, 104 6, 709-19
Tepe, N M; Lorenz, J N; Yatani, A; Dash, R; Kranias, E G; Dorn, G W; Liggett, S B 1999. Altering the receptor-effector ratio by transgenic overexpression of type V adenylyl cyclase: enhanced basal catalytic activity and function without increased cardiomyocyte beta-adrenergic signalling. Biochemistry, 38 50, 16706-13
Grupp, I L; Lorenz, J N; Walsh, R A; Boivin, G P; Rindt, H 1998. Overexpression of alpha1B-adrenergic receptor induces left ventricular dysfunction in the absence of hypertrophy. The American journal of physiology, 275 4 Pt 2, H1338-50
Meneton, P; Schultheis, P J; Greeb, J; Nieman, M L; Liu, L H; Clarke, L L; Duffy, J J; Doetschman, T; Lorenz, J N; Shull, G E 1998. Increased sensitivity to K+ deprivation in colonic H,K-ATPase-deficient mice. The Journal of clinical investigation, 101 3, 536-42
Schultheis, P J; Clarke, L L; Meneton, P; Miller, M L; Soleimani, M; Gawenis, L R; Riddle, T M; Duffy, J J; Doetschman, T; Wang, T; Giebisch, G; Aronson, P S; Lorenz, J N; Shull, G E 1998. Renal and intestinal absorptive defects in mice lacking the NHE3 Na+/H+ exchanger. Nature genetics, 19 3, 282-5
Schultheis, P J; Lorenz, J N; Meneton, P; Nieman, M L; Riddle, T M; Flagella, M; Duffy, J J; Doetschman, T; Miller, M L; Shull, G E 1998. Phenotype resembling Gitelman's syndrome in mice lacking the apical Na+-Cl- cotransporter of the distal convoluted tubule. The Journal of biological chemistry, 273 44, 29150-5
Stockelman, M G; Lorenz, J N; Smith, F N; Boivin, G P; Sahota, A; Tischfield, J A; Stambrook, P J 1998. Chronic renal failure in a mouse model of human adenine phosphoribosyltransferase deficiency. The American journal of physiology, 275 1 Pt 2, F154-63
Williams, R V; Lorenz, J N; Witt, S A; Hellard, D T; Khoury, P R; Kimball, T R 1998. End-systolic stress-velocity and pressure-dimension relationships by transthoracic echocardiography in mice. The American journal of physiology, 274 5 Pt 2, H1828-35
Zhou, M; Sutliff, R L; Paul, R J; Lorenz, J N; Hoying, J B; Haudenschild, C C; Yin, M; Coffin, J D; Kong, L; Kranias, E G; Luo, W; Boivin, G P; Duffy, J J; Pawlowski, S A; Doetschman, T 1998. Fibroblast growth factor 2 control of vascular tone. Nature medicine, 4 2, 201-7
Colbert, M C; Hall, D G; Kimball, T R; Witt, S A; Lorenz, J N; Kirby, M L; Hewett, T E; Klevitsky, R; Robbins, J 1997. Cardiac compartment-specific overexpression of a modified retinoic acid receptor produces dilated cardiomyopathy and congestive heart failure in transgenic mice. The Journal of clinical investigation, 100 8, 1958-68
D'Angelo, D D; Sakata, Y; Lorenz, J N; Boivin, G P; Walsh, R A; Liggett, S B; Dorn, G W 1997. Transgenic Galphaq overexpression induces cardiac contractile failure in mice. Proceedings of the National Academy of Sciences of the United States of America, 94 15, 8121-6
Liu, L H; Paul, R J; Sutliff, R L; Miller, M L; Lorenz, J N; Pun, R Y; Duffy, J J; Doetschman, T; Kimura, Y; MacLennan, D H; Hoying, J B; Shull, G E 1997. Defective endothelium-dependent relaxation of vascular smooth muscle and endothelial cell Ca2+ signaling in mice lacking sarco(endo)plasmic reticulum Ca2+-ATPase isoform 3. The Journal of biological chemistry, 272 48, 30538-45
Lorenz, J N; Kranias, E G 1997. Regulatory effects of phospholamban on cardiac function in intact mice. The American journal of physiology, 273 6 Pt 2, H2826-31
Lorenz, J N; Paul, R J 1997. Dependence of Ca2+ channel currents on endogenous and exogenous sources of ATP in portal vein smooth muscle. The American journal of physiology, 272 2 Pt 2, H987-94
Lorenz, J N; Robbins, J 1997. Measurement of intraventricular pressure and cardiac performance in the intact closed-chest anesthetized mouse. The American journal of physiology, 272 3 Pt 2, H1137-46
Tam, E S; Ferguson, D G; Bielefeld, D R; Lorenz, J N; Cohen, R M; Pun, R Y 1997. Norepinephrine-mediated calcium signaling is altered in vascular smooth muscle of diabetic rat. Cell calcium, 21 2, 143-50
Turki, J; Lorenz, J N; Green, S A; Donnelly, E T; Jacinto, M; Liggett, S B 1996. Myocardial signaling defects and impaired cardiac function of a human beta 2-adrenergic receptor polymorphism expressed in transgenic mice. Proceedings of the National Academy of Sciences of the United States of America, 93 19, 10483-8
Lorenz, J N; Bielefeld, D R; Sperelakis, N 1994. Regulation of calcium channel current in A7r5 vascular smooth muscle cells by cyclic nucleotides. The American journal of physiology, 266 6 Pt 1, C1656-63