May 23, 2008—The second annual retreat of the Systems Biology & Physiology Program was held on Friday, May 23, 2008 at Cincinnati Children's Hospital. The retreat showcased the research of students and faculty in the SBP program, and highlighted systems approaches to research bridging modern physiology and clinical medicine.

The 2008 Daniel L Kline Lecturer in Systems Biology & Physiology, Roger Brent, PhD (pictured), of the Molecular Sciences Institute, Berkeley, CA, presented the keynote address "Systems biology of cell-signaling systems: It's all about the information". After the address, Mrs Vivian Kline, the wife of the late Daniel L Kline, PhD (who chaired the department of physiology from 1966 to 1983), presented Dr Brent with a plaque.

More than 20 trainees—including undergraduates, PhD students and postdoctoral trainees—gave poster presentations of their work, and prizes were awarded for the top-ranked poster presentations.

Program

8:00 am	Registration, Poster Setup and Continental Breakfast
9:00 am	Opening Remarks Richard J Paul, PhD Director, Systems Biology & Physiology Program, and Professor, Molecular & Cellular Physiology, University of Cincinnati
9:15 am	Keynote Address Roger Brent, PhD Director, Molecular Research Institute, Berkeley, CA Systems biology of cell-signaling systems: It's all about the information
10:15 am	Arnold Strauss, MD Professor, Pediatrics, University of Cincinnati, and Director, Cincinnati Children's Hospital Research Foundation Perinatal adaptation to a mitochondrial fatty-acid oxidation defect
10:45 am	Break
11:00 am	Jay R Hove, PhD Associate Professor, Molecular & Cellular Physiology, University of Cincinnati Dynamic physiology in zebrafish
11:30 am	Jaroslav Meller, PhD Associate Professor, Environmental Health and Biomedical Engineering, University of Cincinnati, and Biomedical Informatics, Cincinnati Children's Hospital Functional genomics and systems biology of cell-signaling systems: It's all about protein-protein interactions
12:00 pm	Timothy A Pritts, MD Assistant Professor, Surgery, University of Cincinnati Systems biology in the ICU: What is the role of the bridge tender?
12:30 pm	Lunch and Poster Session See prizewinners
2:30 pm	Graduate Students' Video Presentation
3:00 pm	Trainee Presentations Vaibhav Pai, BSc PhD Student [Horseman Lab] Systems biology approaches to reveal novel aspects of mammary gland physiology Ali Shawki Undergraduate Student [Mackenzie Lab] Molecular impact of human divalent metal-ion transporter DMT1 mutations associated with disease phenotypes
3:30 pm	Integrating your favorite 'omics with vertebrate physiology Interactive small-group session led by Edward C Jauch, MD, with table moderators Joseph F Clark, PhD, Nelson D Horseman, PhD, Marshall H Montrose, PhD and Richard J Paul, PhD
4:30 pm	Awards Ceremony and Closing Remarks Marshall H Montrose, PhD Professor and Chair, Molecular & Cellular Physiology, University of Cincinnati
4:45 pm	Wine & Cheese Debriefing, resolving, and implementation

Poster Prizewinners

1st Prize	Heather Hale, BS PhD Student [Gregerson Lab] Human-compatible animal models for preclinical research on prolactin in breast cancer Heather R Hale, and Karen A Gregerson Elizabeth Loreaux, BS PhD Student Lingrel Lab] Saline loading stimulates greater natriuresis in mice expressing ouabain-sensitive α1 Na,K-ATPase Elizabeth L Loreaux, Baksho Kaul, John N Lorenz, and Jerry S Lingrel
3rd Prize	Chang Xiao, MD PhD Student [Zavros Lab] Loss of sonic hedgehog (Shh) results in disruption of tight-junction protein expression and differentiation of the gastric epithelium Xiao Chang, Meliss A Orr, David J Robbins, Frederic Hollande, and Yana Zavros

Systems Biology & Physiology (SBP) PhD student Heather Hale presents her poster to the judges (Drs Zavros, Banks, and Clark) during the SBP program retreat held at Cincinnati Children's Hospital on Friday, May 23, 2008. Read the reports from other SBP retreats: 2007 • 2009