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Anthony Illing Wins Award for Excellence in Undergraduate Research
 April 30, 2007—Anthony Illing, an undergraduate student in the laboratory of Bryan Mackenzie, PhD, today received the David Bruce Award for Excellence in Undergraduate Research from the American Physiological Society (APS). Tony was judged on his poster presentation "Substrate profile and metal-ion selectivity of the human divalent metal-ion transporter DMT1" [view abstract] at Experimental Biology 2007 in Washington, DC.
The Mackenzie lab is applying a combination of fluorescence, voltage-clamp and radiotracer approaches in Xenopus oocytes expressing the iron transporter DMT1 to examine its full substrate profile. DMT1 is required for intestinal iron uptake and for iron utilization by erythroid precursor cells. Tony found that DMT1 also transports the essential metals cobalt and manganese, and the toxic metal cadmium, but that it is unlikely to contribute to the absorption of zinc and copper. Tony performed the work while on co-op assignments in the Mackenzie lab. Co-authors on the study include undergraduates Ali Shawki and Christopher Cunningham.
Tony was one of six recipients of this year's awards, named after the dedicated physiology educator and former chair of the APS teaching section, David S Bruce, PhD (1939–2000).
Tony, a native of Cincinnati, will graduate this summer BS in chemical engineering, and will enter medical school at Indiana University in the fall.
Anthony Illing stands by his Experimental Biology 2007 poster presentation at the
David Bruce Awards presentation ceremony in Washington, DC, April 30, 2007.
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