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Richard J. Paul, PhD
Professor
Director, PhD Program in Systems Biology & Physiology
richard.paul@uc.edu
My research interests focus on the mechanisms underlying the control of smooth muscle contractility and its coordination with metabolism. We use gene-altered mice, opening new avenues for studying basic smooth muscle mechanisms and diseases from coronary artery vasospasm to hypertension.
Visit the Paul Laboratory Homepage. |
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Selected Publications:
- Brian Oloizia and Richard J Paul (2008) Ca2+ clearance and contractility in vascular smooth muscle: Evidence from gene-altered murine models. J Mol Cell Cardiol, in press. [Review]
View original publication at ScienceDirect.com.
- Ronald M Lynch, Craig S Weber, Kevin D Nullmeyer, Edwin D W Moore and Richard J Paul (2008) Clearance of store-released Ca2+ by the Na+-Ca2+ exchanger is diminished in aortic smooth muscle from Na+-K+-ATPase ?2-isoform gene-ablated mice. Am J Physiol Heart Circ Physiol 294, H1407-H1416.
View original publication at AJP:Heart Online.
- Tracy J Pritchard, Michelle Parvatiyar, Daniel P Bullard, Ronald M Lynch, John N Lorenz and Richard J Paul (2007) Transgenic mice expressing Na+-K+-ATPase in smooth muscle decreases blood pressure. Am J Physiol Heart Circ Physiol 293, H1172-H1182.
View original publication at AJP:Heart Online.
- Robert L Wardle, Min Gu, Yukisato Ishida and Richard J Paul (2007) Rho kinase is an effector underlying Ca2+-desensitizing hypoxic relaxation in porcine coronary artery. Am J Physiol Heart Circ Physiol 293, H23-H29.
View original publication at AJP:Heart Online.
- Anne F Martin, Sunita Bhatti, Gail J Pyne-Geithman, Mariam Farjah, Vlasios Manaves, Lori Walker, Roberta Franks, Arthur R Strauch and Richard J Paul (2007) Expression and function of COOH-terminal myosin heavy chain isoforms in mouse smooth muscle. Am J Physiol Cell Physiol 293, C238-C245.
View original publication at AJP:Cell Online.
- Li Liu, Yukisato Ishida, Gbolahan Okunade, G J Pyne-Geithman, Gary E Shull and Richard J Paul (2007) Distinct roles of PMCA isoforms in Ca2+ homeostasis of bladder smooth muscle: evidence from PMCA gene-ablated mice. Am J Physiol Cell Physiol 292, C423-C431.
View original publication at AJP:Cell Online.
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