Ganglioglioma

Findings:
Axial FLAIR images show an area of faint hypointensity in the right medial temporal lobe, without significant associated mass effect or edema. This area has bright gyriform enhancement.

Differential Diagnosis:
ganglioglioma, DNET, gangliocytoma, oligodendroglioma, focal encephalitis or aging infarct less likely.

Discussion:
Gangliogliomas are low grade tumors composed of  glial cells and differentiated neurons, are most common in the temporal lobes, and represent approximately 1% of intracranial neoplasms. Clinically, these tumors present with partial complex seizures and/or hypothalamic dysfunction at age 10-20. 5% are associated with additional anomalies (callosal agenesis, Down's). The tumors are calcified in 35%, show no significant mass effect or edema, and have variable enhancement.

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