• David Ficker, MD
  • Associate Professor
  • Clinical Office:
    UC Health Physicians Office – Clifton
    222 Piedmont Avenue, Ste. 3200
    Cincinnati, OH 45219
  • Phone: 513-475-8730
  • Email: david.ficker@uc.edu

    Research/Clinical Interests:

  • Epilepsy, Seizure Disorders, Electroencephalogram

    Education/Credentials:

  • Medical Degree: University of Cincinnati
  • Internship: Christ Hospital, Cincinnati, OH
  • Residency: Mayo Clinic
  • Fellowship: Mayo Clinic

Board Certifications & Licenses:

  • Diplomate, American Board of Psychiatry and Neurology, 01/27/1998, certificate valid through 12/31/2017
  • Diplomate in Clinical Neurophysiology, American Board of Psychiatry and Neurology, 04/13/1999, certificate valid through 12/31/2009
  • Maintenance of Certification, Neurology American Board of Psychiatry and Neurology, 2007

Peer Reviewed Publications (in chronological order):

  • Hartings, J. A., Wilson, J. A., Hinzman, J. M., Pollandt, S., Dreier, J. P., DiNapoli, V., Ficker, D. M., Shutter, L. A., & Andaluz, N. (2014). Spreading depression in continuous electroencephalography of brain trauma. . Annals of Neurology.
  • Knight, W. A., Hart, K. W., Adeoye, O. M., Bonomo, J. B., Keegan, S. P., Ficker, D. M., Szaflarski, J. P., Privitera, M. D., & Lindsell, C. J. (2013). The incidence of seizures in patients undergoing therapeutic hypothermia after resuscitation from cardiac arrest. . Epilepsy Research , 106 (3) , 396-402.
  • D'Souza, W. J., Quinn, S. J., Fryer, J. L., Taylor, B. V., Ficker, D. M., O'Brien, T. J., Pearce, N., & Cook, M. J. (2012). The prevalence and demographic distribution of treated epilepsy: a community-based study in Tasmania, Australia. . Acta Neurologica Scandinavica , 125 (2) , 96-104.
  • Shafer, P. O., Buelow, J., Ficker, D. M., Pugh, M. J., Kanner, A. M., Dean, P., & Levisohn, P. (2011). Risk of adverse events on epilepsy monitoring units: a survey of epilepsy professionals. . Epilepsy & Behavior : E & B , 20 (3) , 502-5.
  • Meador,K. J., Baker,G. A., Browning,N., Clayton-Smith,J., Combs-Cantrell,D. T., Cohen,M., Kalayjian,L. A., Kanner,A., Liporace,J. D., Pennell,P. B., Privitera,M., Loring,D. W., NEAD Study Group (2009). Cognitive function at 3 years of age after fetal exposure to antiepileptic drugs . The New England Journal of Medicine , 360 (16) , 1597 , 1605.
  • D'Souza,W. J., Fryer,J. L., Quinn,S. J., Taylor,B. V., Ficker,D. M., O'Brien,T. J., Pearce,N. E., Cook,M. J. (2007). The Tasmanian Epilepsy Register--a community-based cohort. Background and methodology for patient recruitment from the Australian national prescription database . Neuroepidemiology , 29 (3-4) , 255 , 263.
  • D'Souza, W. J., Fryer, J. L., Quinn, S. J., Taylor, B. V., Ficker, D. M., O'Brien, T. J., Pearce, N. E., & Cook, M. J. (2007). The Tasmanian Epilepsy Register--a community-based cohort. Background and methodology for patient recruitment from the Australian national prescription database. . Neuroepidemiology , 29 (3-4) , 255-63.
  • Meador,K. J., Baker,G. A., Finnell,R. H., Kalayjian,L. A., Liporace,J. D., Loring,D. W., Mawer,G., Pennell,P. B., Smith,J. C., Wolff,M. C., NEAD Study Group (2006). In utero antiepileptic drug exposure: fetal death and malformations . Neurology , 67 (3) , 407 , 412.
  • Szaflarski,M., Szaflarski,J. P., Privitera,M. D., Ficker,D. M., Horner,R. D. (2006). Racial/ethnic disparities in the treatment of epilepsy: what do we know? What do we need to know? . Epilepsy & Behavior : E & B , 9 (2) , 243 , 264.
  • Szaflarski, M., Szaflarski, J. P., Privitera, M. D., Ficker, D. M., & Horner, R. D. (2006). Racial/ethnic disparities in the treatment of epilepsy: what do we know? What do we need to know? . Epilepsy & Behavior : E & B , 9 (2) , 243-64.
  • Ficker,D. M., Privitera,M., Krauss,G., Kanner,A., Moore,J. L., Glauser,T. (2005). Improved tolerability and efficacy in epilepsy patients with extended-release carbamazepine . Neurology , 65 (4) , 593 , 595.
  • Goldberg-Stern,H., Gadoth,N., Ficker,D., Privitera,M. (2005). The effect of age and structural lesions on postictal language impairment . Seizure : the Journal of the British Epilepsy Association , 14 (1) , 62 , 65.
  • Ficker, D. M., Privitera, M., Krauss, G., Kanner, A., Moore, J. L., & Glauser, T. (2005). Improved tolerability and efficacy in epilepsy patients with extended-release carbamazepine. . Neurology , 65 (4) , 593-5.
  • Privitera,M., Ficker,D. M. (2004). Assessment of adverse events and quality of life in epilepsy: design of a new community-based trial . Epilepsy & Behavior : E & B , 5 (6) , 841 , 846.
  • Tang,Y., Lu,A., Ran,R., Aronow,B. J., Schorry,E. K., Hopkin,R. J., Gilbert,D. L., Glauser,T. A., Hershey,A. D., Richtand,N. W., Privitera,M., Dalvi,A., Sahay,A., Szaflarski,J. P., Ficker,D. M., Ratner,N., Sharp,F. R. (2004). Human blood genomics: distinct profiles for gender, age and neurofibromatosis type 1 . Brain Research.Molecular Brain Research , 132 (2) , 155 , 167.
  • Tang,Y., Glauser,T. A., Gilbert,D. L., Hershey,A. D., Privitera,M. D., Ficker,D. M., Szaflarski,J. P., Sharp,F. R. (2004). Valproic acid blood genomic expression patterns in children with epilepsy - a pilot study . Acta Neurologica Scandinavica , 109 (3) , 159 , 168.
  • Tang, Y., Lu, A., Ran, R., Aronow, B. J., Schorry, E. K., Hopkin, R. J., Gilbert, D. L., Glauser, T. A., Hershey, A. D., Richtand, N. W., Privitera, M., Dalvi, A., Sahay, A., Szaflarski, J. P., Ficker, D. M., Ratner, N., & Sharp, F. R. (2004). Human blood genomics: distinct profiles for gender, age and neurofibromatosis type 1. . Brain Research. Molecular Brain Research , 132 (2) , 155-67.
  • Privitera, M., & Ficker, D. M. (2004). Assessment of adverse events and quality of life in epilepsy: design of a new community-based trial. . Epilepsy & Behavior : E & B , 5 (6) , 841-6.
  • Tang, Y., Glauser, T. A., Gilbert, D. L., Hershey, A. D., Privitera, M. D., Ficker, D. M., Szaflarski, J. P., & Sharp, F. R. (2004). Valproic acid blood genomic expression patterns in children with epilepsy - a pilot study. . Acta Neurologica Scandinavica , 109 (3) , 159-68.
  • Rose,A. B., McCabe,P. H., Gilliam,F. G., Smith,B. J., Boggs,J. G., Ficker,D. M., Moore,J. L., Passaro,E. A., Bazil,C. W., Consortium for Research in Epilepsy (2003). Occurrence of seizure clusters and status epilepticus during inpatient video-EEG monitoring . Neurology , 60 (6) , 975 , 978.
  • Szaflarski,J. P., Szaflarski,M., Hughes,C., Ficker,D. M., Cahill,W. T., Privitera,M. D. (2003). Psychopathology and quality of life: psychogenic non-epileptic seizures versus epilepsy . Medical Science Monitor : International Medical Journal of Experimental and Clinical Research , 9 (4) , CR113 , 8.
  • Szaflarski,J. P., Hughes,C., Szaflarski,M., Ficker,D. M., Cahill,W. T., Li,M., Privitera,M. D. (2003). Quality of life in psychogenic nonepileptic seizures . Epilepsia , 44 (2) , 236 , 242.
  • Szaflarski, J. P., Szaflarski, M., Hughes, C., Ficker, D. M., Cahill, W. T., & Privitera, M. D. (2003). Psychopathology and quality of life: psychogenic non-epileptic seizures versus epilepsy. . Medical Science Monitor : International Medical Journal of Experimental and Clinical Research , 9 (4) , CR113-8.
  • Rose, A. B., McCabe, P. H., Gilliam, F. G., Smith, B. J., Boggs, J. G., Ficker, D. M., Moore, J. L., Passaro, E. A., & Bazil, C. W. (2003). Occurrence of seizure clusters and status epilepticus during inpatient video-EEG monitoring. . Neurology , 60 (6) , 975-8.
  • Szaflarski, J. P., Hughes, C., Szaflarski, M., Ficker, D. M., Cahill, W. T., Li, M., & Privitera, M. D. (2003). Quality of life in psychogenic nonepileptic seizures. . Epilepsia , 44 (2) , 236-42.
  • Welty,T. E., Gidal,B. E., Ficker,D. M., Privitera,M. D. (2002). Levetiracetam: a different approach to the pharmacotherapy of epilepsy . The Annals of Pharmacotherapy , 36 (2) , 296 , 304.
  • Privitera,M. D., Welty,T. E., Ficker,D. M., Welge,J. (2002). Vagus nerve stimulation for partial seizures . Cochrane Database of Systematic Reviews (Online) , (1) (1) , CD002896.
  • Welty, T. E., Gidal, B. E., Ficker, D. M., & Privitera, M. D. (2002). Levetiracetam: a different approach to the pharmacotherapy of epilepsy. . The Annals of Pharmacotherapy , 36 (2) , 296-304.
  • Privitera, M. D., Welty, T. E., Ficker, D. M., & Welge, J. (2002). Vagus nerve stimulation for partial seizures. . Cochrane Database of Systematic Reviews (Online) (1) , CD002896.
  • Ficker,D. M., Shukla,R., Privitera,M. D. (2001). Postictal language dysfunction in complex partial seizures: effect of contralateral ictal spread . Neurology , 56 (11) , 1590 , 1592.
  • Ficker, D. M., Shukla, R., & Privitera, M. D. (2001). Postictal language dysfunction in complex partial seizures: effect of contralateral ictal spread. . Neurology , 56 (11) , 1590-2.
  • Szaflarski,J. P., Ficker,D. M., Cahill,W. T., Privitera,M. D. (2000). Four-year incidence of psychogenic nonepileptic seizures in adults in hamilton county, OH . Neurology , 55 (10) , 1561 , 1563.
  • Ficker,D. M. (2000). Sudden unexplained death and injury in epilepsy . Epilepsia , 41 Suppl 2 , S7 , 12.
  • Szaflarski, J. P., Ficker, D. M., Cahill, W. T., & Privitera, M. D. (2000). Four-year incidence of psychogenic nonepileptic seizures in adults in hamilton county, OH. . Neurology , 55 (10) , 1561-3.
  • Ficker, D M (2000). Sudden unexplained death and injury in epilepsy. . Epilepsia , 41 Suppl 2 , S7-12.
  • Ficker,D. M., So,E. L., Mosewich,R. K., Radhakrishnan,K., Cascino,G. D., Sharbrough,F. W. (1999). Improvement and deterioration of seizure control during the postsurgical course of epilepsy surgery patients . Epilepsia , 40 (1) , 62 , 67.
  • Ficker, D. M., So, E. L., Mosewich, R. K., Radhakrishnan, K., Cascino, G. D., & Sharbrough, F. W. (1999). Improvement and deterioration of seizure control during the postsurgical course of epilepsy surgery patients. . Epilepsia , 40 (1) , 62-7.
  • Ficker,D. M., Cascino,G. D., Clements,I. P. (1998). Cardiac asystole masquerading as temporal lobe epilepsy . Mayo Clinic Proceedings.Mayo Clinic , 73 (8) , 784 , 786.
  • Ficker,D. M., So,E. L., Shen,W. K., Annegers,J. F., O'Brien,P. C., Cascino,G. D., Belau,P. G. (1998). Population-based study of the incidence of sudden unexplained death in epilepsy . Neurology , 51 (5) , 1270 , 1274.
  • Ficker, D. M., So, E. L., Shen, W. K., Annegers, J. F., O'Brien, P. C., Cascino, G. D., & Belau, P. G. (1998). Population-based study of the incidence of sudden unexplained death in epilepsy. . Neurology , 51 (5) , 1270-4.
  • Ficker, D. M., Cascino, G. D., & Clements, I. P. (1998). Cardiac asystole masquerading as temporal lobe epilepsy. . Mayo Clinic Proceedings. Mayo Clinic , 73 (8) , 784-6.
  • Ficker,D. M., Westmoreland,B. F., Sharbrough,F. W. (1997). Epileptiform abnormalities in hepatic encephalopathy . Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society , 14 (3) , 230 , 234.
  • Ficker DM, Westmoreland BF, Sharbrough FW (1997). (In Press). Lesional temporal lobe epilepsy; ictal semiology and operative outcome. . Epilepsy , 1997 (10) , 298.
  • Ficker, D. M., Westmoreland, B. F., & Sharbrough, F. W. (1997). Epileptiform abnormalities in hepatic encephalopathy. . Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society , 14 (3) , 230-4.
  • Ficker,D. M., Hammack,J. E. (1995). Primary central nervous system lymphoma presenting as autonomic dysfunction . Journal of Neuro-oncology , 23 (3) , 245 , 248.
  • Ficker, D. M., & Hammack, J. E. (1995). Primary central nervous system lymphoma presenting as autonomic dysfunction. . Journal of Neuro-oncology , 23 (3) , 245-8.

    Research Grants:

  • 2006 to 2011 Co-investigator: The Greater Cincinnati/Northern Kentucky NETT Network Hub and Spoke System. 1U10NS058982-01. Principal investigator of clinical center: Arthur Pancioli, M.D.
  • 2007 to 2009 Principal Investigator: Neurobiology of depression and suicidality in epilepsy: a functional MRI study. Epilepsy Foundation Targeted Research Initiative for Mood Disorders
  • 2005 to present Co-investigator: An open-label extension trial to determine safety and efficacy of long-term oral SPM 927 in patients with partial seizures. Schwartz Pharma.
  • 2007 to 2009 Principal Investigator: An international, double-blind, parallel-group, placebo-controlled, randomized study: evaluation of the efficacy and safety of brivaracetam in subjects (> 16 to 70 years old) with partial onset seizures. UCB Pharma.
  • 2008 to present Principal Investigator: An open-label multicenter, follow-up trial to evaluate the long-term safety and efficacy of brivaracetam used as adjunctive treatment at a flexible dose up to a maximum of 150 mg/day in subjects aged 16 years or older suffering from epilepsy. UCB Pharma
  • 2008 to present Principal Investigator: Double-Blind, Placebo-Controlled, Efficacy and Safety Study of Clobazam (0.25, 0.5 and 1.0 mg/kg/day) in Patients with Lennox-Gastaut Syndrome. Ovation Pharmaceuticals
  • 2008 to present Principal Investigator: Safety and Effectiveness of Open Label Clobazam in Subjects with Lennox-Gastaut Syndrome. Ovation Pharmaceuticals
  • 2008 to present Co-Investigator: A double-blind, placebo-controlled, dose-escalation, parallel-group study to evaluate the efficacy and safety of E207 (perampanel) given as adjunctive therapy in subjects with refractory partial seizures. Eisai
  • 2008 to present Co-Investigator: A 14-month open-label extension phase of the double-blind, placebo-controlled, dose-escalation, parallel-group studies to evaluate the efficacy and safety of E2007 (perampanel) given as adjunctive therapy in subjects with refractory partial seizures. Eisai
  • University of Cincinnati Neuroscience Institute. Aggressive Management of Epilepsy in Adults, PI, Closed.
  • 1-U01-NS-042372-01-A1-S0-E0 National Institute of Neurological Disorders and Stroke. Early Randomized Surgical Epilepsy Trial (ERSET), PI, Closed.
  • 5-K23-NS-02170-05-A0-S0-E0 National Institute of Neurological Disorders and Stroke. Quality of Life in Newly Diagnosed Epilepsy and Seizures, PI, Closed.
  • 005064-001 Epilepsy Foundation. Neurobiology of Depression and Suicidality in Epilepsy: A Functional MRI Study, PI, Active.

Recent Awards/Honors:

  • 1988 Phi Beta Kappa Honor Society
  • 1992 Alpha Omega Alpha Medical Honor Society
  • 2000 to 2004 Examiner, American Board of Psychiatry and Neurology
  • 2000 to 2006 Mentored Patient-Oriented Research Career Development Award, National Institutes of Health (K23)
  • 2002 Named in Who’s Who in Medicine and Healthcare 2002-3 edition
  • 2004 Cincinnati Business Courier. Forty under 40
  • 2005 Best Doctors in America 2005-2007 (www.bestdoctors.com)
  • 2005 Cincinnati Magazine Top Doctors
  • 2007 Best Doctors in America 2007-2008
  • 2008 Attendee, American Academy of Neurology Palatucci Advocacy Leadership Forum
  • 2009 Attendee, American Academy of Neurology on the Hill

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