• Michael Miles, PharmD
  • Professor of Pediatrics (Neuropharmacology)
  • Clinical Office:
    Cincinnati Children's Hospital Medical Center
    3333 Burnet Avenue
    Cincinnati, OH 45229
  • Phone: 513-636-7871
  • Email: michael.miles@cchmc.org

    Research/Clinical Interests:

  • Pediatric Pharmacology

    Education/Credentials:

  • PharmD: University of Texas at Austin
  • Specialty Residency: University of Texas at Austin

Board Certifications & Licenses:

  • Pharmacy, 1976

Peer Reviewed Publications (in chronological order):

  • Cortes, S., Esteves, C., Maurício, I., Maia, C., Cristovão, J. M., Miles, M., & Campino, L. (2012). In vitro and in vivo behaviour of sympatric Leishmania (V.) braziliensis, L. (V.) peruviana and their hybrids. . Parasitology , 139 (2) , 191-9.
  • Miles, L., Miles, M. V., Horn, P. S., Degrauw, T. J., Wong, B. L., & Bove, K. E. (2012). Importance of muscle light microscopic mitochondrial subsarcolemmal aggregates in the diagnosis of respiratory chain deficiency. . Human Pathology.
  • Miles, M. V., Miles, L., Horn, P. S., & DeGrauw, T. J. (2012). Enzyme inducing antiepileptic drugs are associated with mitochondrial proliferation and increased cytochrome c oxidase activity in muscle of children with epilepsy. . Epilepsy Research , 98 (1) , 76-87.
  • Tang, P. H., & Miles, M. V. (2012). Measurement of oxidized and reduced coenzyme Q in biological fluids, cells, and tissues: an HPLC-EC method. . Methods in Molecular Biology (Clifton, N.J.) , 837 , 149-68.
  • Farris, S. P., & Miles, M. F. (2012). Ethanol modulation of gene networks: implications for alcoholism. . Neurobiology of Disease , 45 (1) , 115-21.
  • Zingales, B., Miles, M. A., Campbell, D. A., Tibayrenc, M., Macedo, A. M., Teixeira, M. M. G., Schijman, A. G., Llewellyn, M. S., Lages-Silva, E., Machado, C. R., Andrade, S. G., & Sturm, N. R. (2011). The revised Trypanosoma cruzi subspecific nomenclature: Rationale, epidemiological relevance and research applications. . Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases.
  • Lauthier, J. J., Tomasini, N., Barnabé, C., Rumi, M. M. M., D'Amato, A. M. A., Ragone, P. G., Yeo, M., Lewis, M. D., Llewellyn, M. S., Basombrío, M. A., Miles, M. A., Tibayrenc, M., & Diosque, P. (2011). Candidate targets for Multilocus Sequence Typing of Trypanosoma cruzi: Validation using parasite stocks from the Chaco Region and a set of reference strains. . Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases.
  • Jackson, K. J., Chen, X., Miles, M. F., Harenza, J., & Damaj, M. I. (2011). The neuropeptide galanin and variants in the GalR1 gene are associated with nicotine dependence. . Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology , 36 (11) , 2339-48.
  • Lewis, M. D., Llewellyn, M. S., Yeo, M., Acosta, N., Gaunt, M. W., & Miles, M. A. (2011). Recent, independent and anthropogenic origins of Trypanosoma cruzi hybrids. . PLoS Neglected Tropical Diseases , 5 (10) , e1363.
  • Yeo, M., Mauricio, I. L., Messenger, L. A., Lewis, M. D., Llewellyn, M. S., Acosta, N., Bhattacharyya, T., Diosque, P., Carrasco, H. J., & Miles, M. A. (2011). Multilocus sequence typing (MLST) for lineage assignment and high resolution diversity studies in Trypanosoma cruzi. . PLoS Neglected Tropical Diseases , 5 (6) , e1049.
  • Kuhls, K., Alam, M. Z., Cupolillo, E., Ferreira, G. E. M., Mauricio, I. L., Oddone, R., Feliciangeli, M. D., Wirth, T., Miles, M. A., & Schönian, G. (2011). Comparative microsatellite typing of new world leishmania infantum reveals low heterogeneity among populations and its recent old world origin. . PLoS Neglected Tropical Diseases , 5 (6) , e1155.
  • Llewellyn, M. S., Rivett-Carnac, J. B., Fitzpatrick, S., Lewis, M. D., Yeo, M., Gaunt, M. W., & Miles, M. A. (2011). Extraordinary Trypanosoma cruzi diversity within single mammalian reservoir hosts implies a mechanism of diversifying selection. . International Journal For Parasitology , 41 (6) , 609-14.
  • Porcu, P., O'Buckley, T. K., Song, S. C., Harenza, J. L., Lu, L., Wang, X., Williams, R. W., Miles, M. F., & Morrow, A. L. (2011). Genetic analysis of the neurosteroid deoxycorticosterone and its relation to alcohol phenotypes: identification of QTLs and downstream gene regulation. . PloS One , 6 (4) , e18405.
  • Franzén, O., Ochaya, S., Sherwood, E., Lewis, M. D., Llewellyn, M. S., Miles, M. A., & Andersson, B. (2011). Shotgun sequencing analysis of Trypanosoma cruzi I Sylvio X10/1 and comparison with T. cruzi VI CL Brener. . PLoS Neglected Tropical Diseases , 5 (3) , e984.
  • Miles, M. V., Putnam, P. E., Miles, L., Tang, P. H., DeGrauw, A. J., Wong, B. L., Horn, P. S., Foote, H. L., & Rothenberg, M. E. (2011). Acquired coenzyme Q10 deficiency in children with recurrent food intolerance and allergies. . Mitochondrion , 11 (1) , 127-35.
  • Wolstenholme, J. T., Warner, J. A., Capparuccini, M. I., Archer, K. J., Shelton, K. L., & Miles, M. F. (2011). Genomic analysis of individual differences in ethanol drinking: evidence for non-genetic factors in C57BL/6 mice. . PloS One , 6 (6) , e21100.
  • Sadlova, J., Yeo, M., Seblova, V., Lewis, M. D., Mauricio, I., Volf, P., & Miles, M. A. (2011). Visualisation of Leishmania donovani fluorescent hybrids during early stage development in the sand fly vector. . PloS One , 6 (5) , e19851.
  • Ocaña-Mayorga, S., Llewellyn, M. S., Costales, J. A., Miles, M. A., & Grijalva, M. J. (2010). Sex, subdivision, and domestic dispersal of Trypanosoma cruzi lineage I in southern Ecuador. . PLoS Neglected Tropical Diseases , 4 (12) , e915.
  • Potkin, S. G., Macciardi, F., Guffanti, G., Fallon, J. H., Wang, Q., Turner, J. A., Lakatos, A., Miles, M. F., Lander, A., Vawter, M. P., & Xie, X. (2010). Identifying gene regulatory networks in schizophrenia. . NeuroImage , 53 (3) , 839-47.
  • Kohli, R., Kirby, M., Xanthakos, S. A., Softic, S., Feldstein, A. E., Saxena, V., Tang, P. H., Miles, L., Miles, M. V., Balistreri, W. F., Woods, S. C., & Seeley, R. J. (2010). High-fructose, medium chain trans fat diet induces liver fibrosis and elevates plasma coenzyme Q9 in a novel murine model of obesity and nonalcoholic steatohepatitis. . Hepatology (Baltimore, Md.) , 52 (3) , 934-44.
  • Li, Z., Mulligan, M. K., Wang, X., Miles, M. F., Lu, L., & Williams, R. W. (2010). A transposon in Comt generates mRNA variants and causes widespread expression and behavioral differences among mice. . PloS One , 5 (8) , e12181.
  • Bhattacharyya, T., Brooks, J., Yeo, M., Carrasco, H. J., Lewis, M. D., Llewellyn, M. S., & Miles, M. A. (2010). Analysis of molecular diversity of the Trypanosoma cruzi trypomastigote small surface antigen reveals novel epitopes, evidence of positive selection and potential implications for lineage-specific serology. . International Journal For Parasitology , 40 (8) , 921-8.
  • Miles, Michael A (2010). Orally acquired Chagas disease: lessons from an urban school outbreak. . The Journal of Infectious Diseases , 201 (9) , 1282-4.
  • Abad-Franch, F., Ferraz, G., Campos, C., Palomeque, F. S., Grijalva, M. J., Aguilar, H. M., & Miles, M. A. (2010). Modeling disease vector occurrence when detection is imperfect: infestation of Amazonian palm trees by triatomine bugs at three spatial scales. . PLoS Neglected Tropical Diseases , 4 (3) , e620.
  • Farris, S. P., Wolen, A. R., & Miles, M. F. (2010). Using expression genetics to study the neurobiology of ethanol and alcoholism. . International Review of Neurobiology , 91 , 95-128.
  • Lewis, M. D., Ma, J., Yeo, M., Carrasco, H. J., Llewellyn, M. S., & Miles, M. A. (2009). Genotyping of Trypanosoma cruzi: systematic selection of assays allowing rapid and accurate discrimination of all known lineages. . The American Journal of Tropical Medicine and Hygiene , 81 (6) , 1041-9.
  • Marcili, A., Lima, L., Valente, V. C., Valente, S. A., Batista, J. S., Junqueira, A. C. V., Souza, A. I., da Rosa, J. A., Campaner, M., Lewis, M. D., Llewellyn, M. S., Miles, M. A., & Teixeira, M. M. G. (2009). Comparative phylogeography of Trypanosoma cruzi TCIIc: new hosts, association with terrestrial ecotopes, and spatial clustering. . Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases , 9 (6) , 1265-74.
  • Lewis, M. D., Llewellyn, M. S., Gaunt, M. W., Yeo, M., Carrasco, H. J., & Miles, M. A. (2009). Flow cytometric analysis and microsatellite genotyping reveal extensive DNA content variation in Trypanosoma cruzi populations and expose contrasts between natural and experimental hybrids. . International Journal For Parasitology , 39 (12) , 1305-17.
  • Jackson, K. J., Walters, C. L., Miles, M. F., Martin, B. R., & Damaj, M. I. (2009). Characterization of pharmacological and behavioral differences to nicotine in C57Bl/6 and DBA/2 mice. . Neuropharmacology , 57 (4) , 347-55.
  • Llewellyn, M. S., Lewis, M. D., Acosta, N., Yeo, M., Carrasco, H. J., Segovia, M., Vargas, J., Torrico, F., Miles, M. A., & Gaunt, M. W. (2009). Trypanosoma cruzi IIc: phylogenetic and phylogeographic insights from sequence and microsatellite analysis and potential impact on emergent Chagas disease. . PLoS Neglected Tropical Diseases , 3 (9) , e510.
  • Llewellyn, M. S., Miles, M. A., Carrasco, H. J., Lewis, M. D., Yeo, M., Vargas, J., Torrico, F., Diosque, P., Valente, V., Valente, S. A., & Gaunt, M. W. (2009). Genome-scale multilocus microsatellite typing of Trypanosoma cruzi discrete typing unit I reveals phylogeographic structure and specific genotypes linked to human infection. . PLoS Pathogens , 5 (5) , e1000410.
  • Miles, M. A., Yeo, M., & Mauricio, I. L. (2009). Genetics. Leishmania exploit sex. . Science (New York, N.Y.) , 324 (5924) , 187-9.
  • Marcili, A., Valente, V. C., Valente, S. A., Junqueira, A. C. V., da Silva, F. M., Pinto, A. Y. d. N., Naiff, R. D., Campaner, M., Coura, J. R., Camargo, E. P., Miles, M. A., & Teixeira, M. M. G. (2009). Trypanosoma cruzi in Brazilian Amazonia: Lineages TCI and TCIIa in wild primates, Rhodnius spp. and in humans with Chagas disease associated with oral transmission. . International Journal For Parasitology , 39 (5) , 615-23.
  • Guo, A., Webb, B. T., Miles, M. F., Zimmerman, M. P., Kendler, K. S., & Zhao, Z. (2009). ERGR: An ethanol-related gene resource. . Nucleic Acids Research , 37 (Database issue) , D840-5.
  • Miles, M. V., Tang, P. H., Miles, L., Steele, P. E., Moye, M. J., & Horn, P. S. (2008). Validation and application of an HPLC-EC method for analysis of coenzyme Q10 in blood platelets. . Biomedical Chromatography : BMC , 22 (12) , 1403-8.
  • Kuhls, K., Chicharro, C., Cañavate, C., Cortes, S., Campino, L., Haralambous, C., Soteriadou, K., Pratlong, F., Dedet, J., Mauricio, I., Miles, M., Schaar, M., Ochsenreither, S., Radtke, O. A., & Schönian, G. (2008). Differentiation and gene flow among European populations of Leishmania infantum MON-1. . PLoS Neglected Tropical Diseases , 2 (7) , e261.
  • Fitzpatrick, S., Feliciangeli, M. D., Sanchez-Martin, M. J., Monteiro, F. A., & Miles, M. A. (2008). Molecular genetics reveal that silvatic Rhodnius prolixus do colonise rural houses. . PLoS Neglected Tropical Diseases , 2 (4) , e210.
  • Miles, M. V., Miles, L., Tang, P. H., Horn, P. S., Steele, P. E., DeGrauw, A. J., Wong, B. L., & Bove, K. E. (2008). Systematic evaluation of muscle coenzyme Q10 content in children with mitochondrial respiratory chain enzyme deficiencies. . Mitochondrion , 8 (2) , 170-80.
  • Kerns, R. T., & Miles, M. F. (2008). Microarray analysis of ethanol-induced changes in gene expression. . Methods in Molecular Biology (Clifton, N.J.) , 447 , 395-410.
  • Miles, M. V., Patterson, B. J., Chalfonte-Evans, M. L., Horn, P. S., Hickey, F. J., Schapiro, M. B., Steele, P. E., Tang, P. H., & Hotze, S. L. (2007). Coenzyme Q10 (ubiquinol-10) supplementation improves oxidative imbalance in children with trisomy 21. . Pediatric Neurology , 37 (6) , 398-403.
  • Miles, Michael V (2007). The uptake and distribution of coenzyme Q10. . Mitochondrion , 7 Suppl , S72-7.
  • Lukes, J., Mauricio, I. L., Schönian, G., Dujardin, J., Soteriadou, K., Dedet, J., Kuhls, K., Tintaya, K. W. Q., Jirk?, M., Chocholová, E., Haralambous, C., Pratlong, F., Oborník, M., Horák, A., Ayala, F. J., & Miles, M. A. (2007). Evolutionary and geographical history of the Leishmania donovani complex with a revision of current taxonomy. . Proceedings of the National Academy of Sciences of the United States of America , 104 (22) , 9375-80.
  • Mauricio, I. L., Gaunt, M. W., Stothard, J. R., & Miles, M. A. (2007). Glycoprotein 63 (gp63) genes show gene conversion and reveal the evolution of Old World Leishmania. . International Journal For Parasitology , 37 (5) , 565-76.
  • Nolder, D., Roncal, N., Davies, C. R., Llanos-Cuentas, A., & Miles, M. A. (2007). Multiple hybrid genotypes of Leishmania (viannia) in a focus of mucocutaneous Leishmaniasis. . The American Journal of Tropical Medicine and Hygiene , 76 (3) , 573-8.
  • Zemanová, E., Jirk?, M., Mauricio, I. L., Horák, A., Miles, M. A., & Lukes, J. (2007). The Leishmania donovani complex: genotypes of five metabolic enzymes (ICD, ME, MPI, G6PDH, and FH), new targets for multilocus sequence typing. . International Journal For Parasitology , 37 (2) , 149-60.
  • Miles, M. F., & Williams, R. W. (2007). Meta-analysis for microarray studies of the genetics of complex traits. . Trends in Biotechnology , 25 (2) , 45-7.
  • Yeo, M., Lewis, M. D., Carrasco, H. J., Acosta, N., Llewellyn, M., da Silva Valente, S. A., de Costa Valente, V., de Arias, A. R., & Miles, M. A. (2007). Resolution of multiclonal infections of Trypanosoma cruzi from naturally infected triatomine bugs and from experimentally infected mice by direct plating on a sensitive solid medium. . International Journal For Parasitology , 37 (1) , 111-20.
  • Tang, P. H., Miles, M. V., Steele, P., Davidson, B. S., Geraghty, S. R., & Morrow, A. L. (2006). Determination of coenzyme Q10 in human breast milk by high-performance liquid chromatography. . Biomedical Chromatography : BMC , 20 (12) , 1336-43.
  • Khisti, R. T., Wolstenholme, J., Shelton, K. L., & Miles, M. F. (2006). Characterization of the ethanol-deprivation effect in substrains of C57BL/6 mice. . Alcohol (Fayetteville, N.Y.) , 40 (2) , 119-26.
  • Miles, M. V., Patterson, B. J., Schapiro, M. B., Hickey, F. J., Chalfonte-Evans, M., Horn, P. S., & Hotze, S. L. (2006). Coenzyme Q10 absorption and tolerance in children with Down syndrome: a dose-ranging trial. . Pediatric Neurology , 35 (1) , 30-7.
  • Goldowitz, D., Matthews, D. B., Hamre, K. M., Mittleman, G., Chesler, E. J., Becker, H. C., Lopez, M. F., Jones, S. R., Mathews, T. A., Miles, M. F., Kerns, R., & Grant, K. A. (2006). Progress in using mouse inbred strains, consomics, and mutants to identify genes related to stress, anxiety, and alcohol phenotypes. . Alcoholism, Clinical and Experimental Research , 30 (6) , 1066-78.
  • Mauricio, I. L., Yeo, M., Baghaei, M., Doto, D., Pratlong, F., Zemanova, E., Dedet, J., Lukes, J., & Miles, M. A. (2006). Towards multilocus sequence typing of the Leishmania donovani complex: resolving genotypes and haplotypes for five polymorphic metabolic enzymes (ASAT, GPI, NH1, NH2, PGD). . International Journal For Parasitology , 36 (7) , 757-69.
  • Kennedy, R. E., Kerns, R. T., Kong, X., Archer, K. J., & Miles, M. F. (2006). SScore: an R package for detecting differential gene expression without gene expression summaries. . Bioinformatics (Oxford, England) , 22 (10) , 1272-4.
  • Sikela, J. M., Maclaren, E. J., Kim, Y., Karimpour-Fard, A., Cai, W., Pollack, J., Hitzemann, R., Belknap, J., McWeeney, S., Kerns, R. T., Downing, C., Johnson, T. E., Grant, K. J., Tabakoff, B., Hoffman, P., Wu, C. C., & Miles, M. F. (2006). DNA microarray and proteomic strategies for understanding alcohol action. . Alcoholism, Clinical and Experimental Research , 30 (4) , 700-8.
  • Kennedy, R. E., Archer, K. J., & Miles, M. F. (2006). Empirical validation of the S-Score algorithm in the analysis of gene expression data. . BMC Bioinformatics , 7 , 154.
  • Chakrabarti, L., Neal, J. T., Miles, M., Martinez, R. A., Smith, A. C., Sopher, B. L., & La Spada, A. R. (2006). The Purkinje cell degeneration 5J mutation is a single amino acid insertion that destabilizes Nna1 protein. . Mammalian Genome : Official Journal of the International Mammalian Genome Society , 17 (2) , 103-10.
  • Hodge, C. W., Miles, M. F., Sharko, A. C., Stevenson, R. A., Hillmann, J. R., Lepoutre, V., Besheer, J., & Schroeder, J. P. (2006). The mGluR5 antagonist MPEP selectively inhibits the onset and maintenance of ethanol self-administration in C57BL/6J mice. . Psychopharmacology , 183 (4) , 429-38.
  • Miles, L., Miles, M. V., Tang, P. H., Horn, P. S., Quinlan, J. G., Wong, B., Wenisch, A., & Bove, K. E. (2005). Ubiquinol: a potential biomarker for tissue energy requirements and oxidative stress. . Clinica Chimica Acta; International Journal of Clinical Chemistry , 360 (1-2) , 87-96.
  • Jones, M. D., Ryan, M., Miles, M. V., Tang, P. H., Fakhoury, T. A., Degrauw, T. J., & Baumann, R. J. (2005). Stability of salivary concentrations of the newer antiepileptic drugs in the postal system. . Therapeutic Drug Monitoring , 27 (5) , 576-9.
  • Matthews, D. B., Bhave, S. V., Belknap, J. K., Brittingham, C., Chesler, E. J., Hitzemann, R. J., Hoffmann, P. L., Lu, L., McWeeney, S., Miles, M. F., Tabakoff, B., & Williams, R. W. (2005). Complex genetics of interactions of alcohol and CNS function and behavior. . Alcoholism, Clinical and Experimental Research , 29 (9) , 1706-19.
  • Miles, L., Miles, M. V., Tang, P. H., Horn, P. S., Wong, B. L., DeGrauw, T. J., Morehart, P. J., & Bove, K. E. (2005). Muscle coenzyme Q: a potential test for mitochondrial activity and redox status. . Pediatric Neurology , 32 (5) , 318-24.
  • Kerns, R. T., Ravindranathan, A., Hassan, S., Cage, M. P., York, T., Sikela, J. M., Williams, R. W., & Miles, M. F. (2005). Ethanol-responsive brain region expression networks: implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice. . The Journal of Neuroscience : the Official Journal of the Society For Neuroscience , 25 (9) , 2255-66.
  • Thibault, C., Hassan, S., & Miles, M. (2005). Using in vitro models for expression profiling studies on ethanol and drugs of abuse. . Addiction Biology , 10 (1) , 53-62.
  • McBride, W. J., Kerns, R. T., Rodd, Z. A., Strother, W. N., Edenberg, H. J., Hashimoto, J. G., Wiren, K. M., & Miles, M. F. (2005). Alcohol effects on central nervous system gene expression in genetic animal models. . Alcoholism, Clinical and Experimental Research , 29 (2) , 167-75.
  • Yeo, M., Acosta, N., Llewellyn, M., Sánchez, H., Adamson, S., Miles, G. A. J., López, E., González, N., Patterson, J. S., Gaunt, M. W., de Arias, A. R., & Miles, M. A. (2005). Origins of Chagas disease: Didelphis species are natural hosts of Trypanosoma cruzi I and armadillos hosts of Trypanosoma cruzi II, including hybrids. . International Journal For Parasitology , 35 (2) , 225-33.
  • York, T. P., Miles, M. F., Kendler, K. S., Jackson-Cook, C., Bowman, M. L., & Eaves, L. J. (2005). Epistatic and environmental control of genome-wide gene expression. . Twin Research and Human Genetics : the Official Journal of the International Society For Twin Studies , 8 (1) , 5-15.
  • Scian, M. J., Stagliano, K. E. R., Ellis, M. A., Hassan, S., Bowman, M., Miles, M. F., Deb, S. P., & Deb, S. (2004). Modulation of gene expression by tumor-derived p53 mutants. . Cancer Research , 64 (20) , 7447-54.
  • Miles, M. V., Horn, P. S., Tang, P. H., Morrison, J. A., Miles, L., DeGrauw, T., & Pesce, A. J. (2004). Age-related changes in plasma coenzyme Q10 concentrations and redox state in apparently healthy children and adults. . Clinica Chimica Acta; International Journal of Clinical Chemistry , 347 (1-2) , 139-44.
  • Steele, P. E., Tang, P. H., DeGrauw, A. J., & Miles, M. V. (2004). Clinical laboratory monitoring of coenzyme Q10 use in neurologic and muscular diseases. . American Journal of Clinical Pathology , 121 Suppl , S113-20.
  • Zemanová, E., Jirk?, M., Mauricio, I. L., Miles, M. A., & Lukes, J. (2004). Genetic polymorphism within the leishmania donovani complex: correlation with geographic origin. . The American Journal of Tropical Medicine and Hygiene , 70 (6) , 613-7.
  • Miles, M. V., Morrison, J. A., Horn, P. S., Tang, P. H., & Pesce, A. J. (2004). Coenzyme Q10 changes are associated with metabolic syndrome. . Clinica Chimica Acta; International Journal of Clinical Chemistry , 344 (1-2) , 173-9.
  • Miles, Michael A (2004). The discovery of Chagas disease: progress and prejudice. . Infectious Disease Clinics of North America , 18 (2) , 247-60, table of con.
  • Miles, M. V., Tang, P. H., Ryan, M. A., Grim, S. A., Fakhoury, T. A., Strawsburg, R. H., DeGrauw, T. J., & Baumann, R. J. (2004). Feasibility and limitations of oxcarbazepine monitoring using salivary monohydroxycarbamazepine (MHD). . Therapeutic Drug Monitoring , 26 (3) , 300-4.
  • Tennison, M., Ali, I., Miles, M. V., D'Cruz, O., Vaughn, B., & Greenwood, R. (2004). Feasibility and acceptance of salivary monitoring of antiepileptic drugs via the US Postal Service. . Therapeutic Drug Monitoring , 26 (3) , 295-9.
  • Sullivan, P. F., Neale, B. M., van den Oord, E., Miles, M. F., Neale, M. C., Bulik, C. M., Joyce, P. R., Straub, R. E., & Kendler, K. S. (2004). Candidate genes for nicotine dependence via linkage, epistasis, and bioinformatics. . American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics , 126B (1) , 23-36.
  • Tang, P. H., Miles, M. V., Miles, L., Quinlan, J., Wong, B., Wenisch, A., & Bove, K. (2004). Measurement of reduced and oxidized coenzyme Q9 and coenzyme Q10 levels in mouse tissues by HPLC with coulometric detection. . Clinica Chimica Acta; International Journal of Clinical Chemistry , 341 (1-2) , 173-84.
  • Kerns, R. T., Zhang, L., & Miles, M. F. (2003). Application of the S-score algorithm for analysis of oligonucleotide microarrays. . Methods (San Diego, Calif.) , 31 (4) , 274-81.
  • Ryan, M., Grim, S. A., Miles, M. V., Tang, P. H., Fakhoury, T. A., Strawsburg, R. H., deGrauw, T. J., & Baumann, R. J. (2003). Correlation of lamotrigine concentrations between serum and saliva. . Pharmacotherapy , 23 (12) , 1550-7.
  • Hassan, S., Duong, B., Kim, K., & Miles, M. F. (2003). Pharmacogenomic analysis of mechanisms mediating ethanol regulation of dopamine beta-hydroxylase. . The Journal of Biological Chemistry , 278 (40) , 38860-9.
  • Miles, M. V., Tang, P. H., Glauser, T. A., Ryan, M. A., Grim, S. A., Strawsburg, R. H., deGrauw, T. J., & Baumann, R. J. (2003). Topiramate concentration in saliva: an alternative to serum monitoring. . Pediatric Neurology , 29 (2) , 143-7.
  • Zhang, L., Miles, M. F., & Aldape, K. D. (2003). A model of molecular interactions on short oligonucleotide microarrays. . Nature Biotechnology , 21 (7) , 818-21.
  • Miles, M. A., Feliciangeli, M. D., & de Arias, A. R. (2003). American trypanosomiasis (Chagas' disease) and the role of molecular epidemiology in guiding control strategies. . BMJ (Clinical Research Ed.) , 326 (7404) , 1444-8.
  • Miles, M. V., Horn, P. S., Morrison, J. A., Tang, P. H., DeGrauw, T., & Pesce, A. J. (2003). Plasma coenzyme Q10 reference intervals, but not redox status, are affected by gender and race in self-reported healthy adults. . Clinica Chimica Acta; International Journal of Clinical Chemistry , 332 (1-2) , 123-32.
  • Elliott, R. C., Miles, M. F., & Lowenstein, D. H. (2003). Overlapping microarray profiles of dentate gyrus gene expression during development- and epilepsy-associated neurogenesis and axon outgrowth. . The Journal of Neuroscience : the Official Journal of the Society For Neuroscience , 23 (6) , 2218-27.
  • Gaunt, M. W., Yeo, M., Frame, I. A., Stothard, J. R., Carrasco, H. J., Taylor, M. C., Mena, S. S., Veazey, P., Miles, G. A. J., Acosta, N., de Arias, A. R., & Miles, M. A. (2003). Mechanism of genetic exchange in American trypanosomes. . Nature , 421 (6926) , 936-9.
  • Hoffman, P. L., Miles, M., Edenberg, H. J., Sommer, W., Tabakoff, B., Wehner, J. M., & Lewohl, J. (2003). Gene expression in brain: a window on ethanol dependence, neuroadaptation, and preference. . Alcoholism, Clinical and Experimental Research , 27 (2) , 155-68.
  • Grim, S. A., Ryan, M., Miles, M. V., Tang, P. H., Strawsburg, R. H., deGrauw, T. J., Fakhoury, T. A., & Baumann, R. J. (2003). Correlation of levetiracetam concentrations between serum and saliva. . Therapeutic Drug Monitoring , 25 (1) , 61-6.
  • Miles, Michael A (2003). Malaria--there could be a third way. . Nature , 421 (6918) , 13.
  • Gibson, W., & Miles, M. (2002). Frontiers in research on parasitic protozoa. . Trends in Parasitology , 18 (12) , 521-2.
  • Wilkinson, S. R., Meyer, D. J., Taylor, M. C., Bromley, E. V., Miles, M. A., & Kelly, J. M. (2002). The Trypanosoma cruzi enzyme TcGPXI is a glycosomal peroxidase and can be linked to trypanothione reduction by glutathione or tryparedoxin. . The Journal of Biological Chemistry , 277 (19) , 17062-71.
  • Gaunt, M. W., & Miles, M. A. (2002). An insect molecular clock dates the origin of the insects and accords with palaeontological and biogeographic landmarks. . Molecular Biology and Evolution , 19 (5) , 748-61.
  • Tang, P. H., Miles, M. V., Steele, P., DeGrauw, A., Chuck, G., Schroer, L., & Pesce, A. (2002). Anticoagulant effects on plasma coenzyme Q(10) estimated by HPLC with coulometric detection. . Clinica Chimica Acta; International Journal of Clinical Chemistry , 318 (1-2) , 127-31.
  • Coura, J. R., Junqueira, A. C. V., Fernandes, O., Valente, S. A. S., & Miles, M. A. (2002). Emerging Chagas disease in Amazonian Brazil. . Trends in Parasitology , 18 (4) , 171-6.
  • Zhang, L., Wang, L., Ravindranathan, A., & Miles, M. F. (2002). A new algorithm for analysis of oligonucleotide arrays: application to expression profiling in mouse brain regions. . Journal of Molecular Biology , 317 (2) , 225-35.
  • Cuba, C. A. C., Abad-Franch, F., Roldan Rodriguez, J., Vargas Vasquez, F., Pollack Velasquez, L., & Miles, M. A. (2002). The triatomines of northern Peru, with emphasis on the ecology and infection by trypanosomes of Rhodnius ecuadoriensis (Triatominae). . Mem & #243;rias Do Instituto Oswaldo Cruz , 97 (2) , 175-83.

Recent Awards/Honors:

  • Best Poster Award for "Coenzyme Q10 Associations with Metabolic Syndrome" at the annual meeting of the Ohio River Valley Regional Conference of the AACC, Dayton, Ohio, 2004, 2004
  • Distinguished Abstract Award for "Coenzyme Q10 Associations with Metabolic Syndrome" presented by the National Academy of Clinical Biochemistry at the annual meeting of the American Association for Clinical Chemistry, Los Angeles, California, July 2004.
  • Chairman of the Ohio River Valley Section of the American Association for Clinical Chemistry, 2006.

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