Department of Molecular & Cellular Physiology
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Fluid Dynamics Research Laboratory Department of Molecular & Cellular Physiology |
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Hove Lab Our laboratory utilizes both physiological and bioengineering approaches to determine the roles of biophysical forces, both within and around living systems, on both healthy and pathological form and function. We are particularly interested in the purported role of biological fluid flow as a morphogen for a variety of human diseases including cardiovascular disease, polycystic kidney disease, and obesity. These research efforts frequently require analysis across a wide range of biological organization, from the intact organism, to the tissues that compose the living conduits through which biofluids flow, down to the developmental gene expression program that serves to effect changes in the functional phenotype. With our colleagues, we are also developing a new suite of phenotyping tools with which to more effectively interrogate a powerful new animal model system of human disease, the zebrafish. |
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