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Research and Clinical

Division of Environmental and Industrial Hygiene

Division of Molecular Toxicology

Division of Epidemiology and Biostatistics

Division of Occupational and Environmental Medicine

Division of Environmental and Industrial Hygiene

Director: C. Scott Clark, Ph.D.

 

Faculty and Research

Aerosol Research and Exposure Assessment Laboratory

Biomechanics and Ergonomics Laboratory

The Environmental and Industrial Hygiene program was initiated in 1952 and has grown considerably since that time into a first-class faculty team widely-recognized for research. Diverse research interests of the nine full-time faculty members and 4 postdoctoral research associates currently includes: air monitoring and characterization in indoor environments contaminated with leaded particles or airborne microorganisms, methods and techniques for aerosol measurement, various aspects of human exposure assessment and risk assessment in occupational and residential environments, exposure reduction and intervention, respiratory protection, interaction between occupational exposure and genetic susceptibility, biomarkers of human exposure, hazardous wastes, physical and chemical risk factors on the neuromuscular performance of humans, and other aspects of environmental and occupational hygiene and ergonomics. Faculty research is supported by grants and contracts from various agencies, such as EPA, NIOSH, US Departments of HUD and Energy, NIST, NIEHS, as well as major industries.

Division of Molecular Toxicology

Director: George D. Leikauf, Ph.D.
 

Faculty and Research

Center for Environmental Genetics

 

Research interests of the 17 full-time faculty include: genetic and molecular toxicology, signal transduction, xenobiotic metabolism, mechanism of genetic susceptibility and carcinogenesis, cell cycle regulation, inhalation toxicology, bioremediation, oxidative stress responses and environmental bioinformatics

Faculty research is supported by individual awards, Center grants and training grants from various institutes of the National Institutes of Health, the United States Environmental Protection Agency and other federal and industrial sources.

Modern methodologies in molecular biology are used, as well as transgenic mouse and inhalation technologies, human cell culture, and current approaches in computational biology.

Division of Epidemiology and Biostatistics

Director: Grace Lemasers, Ph.D.

 

Faculty and Research

Division Web Site

In 1973, of Epidemiology and Biostatistics was revitalized under the direction of Ralph Buncher, and the number of graduates in Biostatistics and Epidemiology dramatically increased. As of 1999, 63 Master's Degree students and 37 Ph.D. students have completed either the Epidemiology or Biostatistics program. The students of the Division have pursued careers in academia, industry, or government. Currently, the Director of the Division is Dr. Grace Lemasters, a fellow of the American College of Epidemiology. The Associate Director for Teaching is Dr. Paul Succop, whose experience includes longitudinal data analysis.

Epidemiology is defined as the distribution and determination of disease and injury within human populations. A goal of the epidemiologist is to identify the factors or agents that are linked with the observed patterns of disease or injury. The program stresses environmental, occupational, quantitative and genetic epidemiology. The field of biostatistics is characterized by data collection, analysis, and interpretation of results, which are tied to environmental and biomedical research. Applied statistical methodology is emphasized in the biostatistics program. The epidemiology and biostatistics programs are closely linked. Faculty and students are involved in research activities in both the university and the community. The focus of the research is on applications in environmental health.

Division of Occupational and Environmental Medicine

Director: James E. Lockey, MD, MS

 

Faculty and Research

Occupational Pulmonary Services

Center for Occupational Health

The Division of Occupational and Environmental Medicine has three major areas of focus:
  1. Training physicians in the specialty of occupational medicine through the University of Cincinnati's ACGME-accredited Occupational Medicine residency training program.
  2. Conducting occupational epidemiologic research of populations exposed to potential hazards within the workplace.
  3. The clinical evaluation of patients with medical conditions potentially related to occupational or environmental exposures.

The Division of Occupational and Environmental Medicine is multi-disciplinary in character and its faculty members have frequent interactions with other divisions within the Department of Environmental Health as well as with the Department of Physical Medicine and Rehabilitation and the Department of Internal Medicine. Extensive use is made of regional and national volunteer faculty with expertise in the field of occupational health.

 RESEARCH

The Division of Occupational and Environmental Medicine is involved in several major areas of research.

The division is evaluating pulmonary toxicity in workers exposed to refractory ceramic fibers (RCF, a type of man-made vitreous fiber). The ongoing pulmonary morbidity and mortality studies of workers involved with RCF manufacturing have identified an association between duration of employment in RCF manufacturing jobs and the occurrence of pleural plaques on chest radiographs. There are ongoing investigations of the health effects of absorbent gelling material, solvent exposure and reproductive / auto-immune disorders, bronchiolitis obliterans, and breath analysis assessment of solvent exposures. Faculty members are also evaluating genotoxic changes associated with low-level solvent and fuel exposures.

Occupational Pulmonary Services within the division is investigating new techniques for evaluating longitudinal pulmonary function testing data for purposes of epidemiologic and individual trending analysis. This analysis is used to distinguish true change from intra and inter-subject variability with serial measurements of lung function. Faculty members are also studying occupational asthma through electronic ambulatory monitoring of lung function and the development of bronchoprovocation challenge procedures. The development and evaluation of respirator fit testing methods and leak checks are another area of active research. Recently, efforts have been directed at the examination of the utility of various fit check maneuvers in assessing adequate fit in wearers of industrial respirators.

Occupational Medicine residents in the training program are very actively involved in a variety of research projects including their Masters Thesis research.

Closely affiliated with the division is the University of Cincinnati's Center for Occupational Health, which is a multi-disciplinary clinical center that provides occupational health services to individuals and communities throughout Cincinnati and the Midwest. Core faculty members from the Division of Occupational and Environmental Medicine and the Division of Epidemiology and Biostatistics administer as well as staff the Center's activities. The Center for Occupational Health is recognized in the field of Occupational and Environmental Health as a comprehensive resource for employers, employees and health professionals.

The division is also involved in offering consultative and clinical services to selected occupational and environmental populations in various exposure settings. Exposures of special interest to faculty members within the division include: metal working fluids, solvents, hydrogen cyanide, mercury, and lead. 

Mailing Address:

Division of Occupational and Environmental Medicine
University of Cincinnati
PO Box 670056
Cincinnati OH 45267-0056

Phone: (513) 558-0030 
Fax: (513) 558-6272