University of Cincinnati, Department of Environmental Health

Division of Epidemiology and Biostatistics

Faculty and Research

Robert L. Bornschein, Ph. D. Kathryn Brown, Ph. D. C. Ralph Buncher, D. Sc. Ranjan Deka, Ph.D. Kim Dietrich, Ph. D. Peter S. Gartside, Ph. D.

Grace Lemasters, Ph. D. Linda Levin, Ph. D. Susan Pinney, Ph. D. Rakesh Shukla, Ph. D. Paul Succop, Ph. D.

Dr. Robert Bornschein, Professor

Research Interests:

Environmental exposures in the developing child

Effects of lead exposure on the developing child

Effects of neurotoxins on the developing and adult nervous systems

Behavioral methodologies for assessing toxicity

Genetic and environmental factors influencing toxicity and recovery of function

Development of community based lead exposure reduction programs

Publications:

Clark, S., Bornschein, R. L., Pan, W., Menrath, W., Roda, S., and Grote, J. (1996). The relationship between surface dust lead loadings on carpets and the blood lead of young children, Environ. Geochem. Health. 18:143-146.

Hwang, Y.-H., Bornschein, R. L., Grote, J., Menrath, W., and Roda, S. (1997). Environmental arsenic exposure of children living near a former copper smelter site, Environ. Res. 72:72-81.

Bornschein, R. (Member of TLC publication group): The treatment of lead-exposed children (TLC) trial: design and recruitment for a study of the effect of oral chelation on growth and development in toddlers, Pediatric and Perinatal Epidemiology. (Submitted).

Service and Outreach:

Dr. Bornschein consults with numerous communities and agencies to promote lead awareness and exposure reduction. The following is a brief list of committees and agencies he has or is currently assisting. Most of these communities are attempting to deal with Superfund sites adjacent to residential neighborhoods.

• Aspen, CO, Technical Advisory Committee
• Butte, MT, Lead Exposure Reduction Program
• Cincinnati Metropolitan Housing authority
• Granite City, IL, City Council
• Leadville, CO, Lead Screening Program
• Palmerton, PA, Environmental Task Force
• Salt Lake City/County Health Department
• Trail, B.C., Lead Task Force

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Dr. M. Kathryn Brown, Research Assistant Professor

Research Activities:

Childhood lead exposure studies at Superfund sites where previous mining, milling and smelting operations contaminated the local environment.

Occupational health studies of current and former workers at Department of Energy nuclear production and research facilities.

Participatory research and collaborative education activities which assist environmentally-impacted communities in developing community-based approaches to environmental pollution, risk assessment and public health services.

Ecological studies and Geographic Information System mapping of environmental contaminants and infant mortality and childhood diseases, including asthma.

Committee Activities:

Center for Environmental Genetics - Community Outreach & Education Program

University of Cincinnati - Health and Environmental Risk Institute

City of Cincinnati - Environmental Advisory Council

Rural Coalition - Environment & Health Committee National Advisory Board

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Dr. Charles Ralph Buncher, Professor

Research in Progress:

1. An occupational cohort mortality study of coke oven workers
2. Lead paint removal and cost factors (with Dr. Scott Clark)
3. Investigation of a device to act as an adjunct to mammography in the detection of breast cancer
4. A study of the Cancer incidence and death rates in the greater Cincinnati area

Recent publications:

Creticos, P. S., Reed, C. E., Norman, P. S., Khoury, J., Adkinson, N. F., Jr., Buncher, C. R., Busse, W. W., Gadde, J., Li, J. T., Richerson, H. B., Rosenthal, R. R., Solomon, W. R., Steinberg, P., Yunginger, J. W. (1996). Ragweed immunotherapy in adult asthma, New England J Med. 334: 501-506.

Radack, K., Martin, V., Wones, R., Buncher, R., Pinney, S., Mandell, K. (1996). Intercorrelations and sources of variability in three Mutagenicity assays: A population-based study, Mutation Research. 350: 295-306.

Russman, B. S., Buncher, C. R., White, M., Samaha, F. J., and Iannaccone, S. T.(1996). Function changes in spinal muscular atrophy II and III, Neurology. 7: 973-976.

Iannaccone, S. T., White, M., Browne, R., Russman, B., Buncher, R., Samaha, F. J. (1997). Muscle fatigue in Spinal Muscular Atrophy, J Child Neurology. 12: 321-326.

Verma, S., Hamilton, K., Hawkins, H. H., Kothari, R., Singal, B., Buncher, R., Nguyen, P., O'Neill, M. (1997). Clinical application of the Ottawa ankle rules for the use of radiography in acute ankle injuries: an independent site assessment, American Journal of Roentgenology. 169: 825-827.

Linz, D. H., Pinney, S. M., Keller, J. D., White, M., Buncher, C. R. (1998). Cluster analysis applied to building-related illness, J Occupational and Environmental Medicine. 40: 165-171.

Awards:

Fellow, American Statistical Association

Fellow, American College of Epidemiology

Dolly Cohen university wide excellence in teaching award

 

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Dr. Ranjan Deka, Associate Professor

Research in Progress:

Dr. Deka’s current research focuses on two areas: (1) population genetics of repeat polymorphisms; and (2) epidemiology and genetics of complex diseases. The objectives of the first area are to understand the population genetic characteristics of microsatellite loci, their utilities in evolutionary and genomic studies, their conservation, mutational mechanisms involved in the generation of new alleles and examining selective forces operating on these loci. Of particular interest is the distribution and dynamics of normal alleles at disease-causing trinucleotide loci – such as Huntington disease, Fragile X syndrome, Myotonic dystrophy – in global human populations. The focus is to understand the predisposing factors that lead to pathological expansion of alleles at these loci. The objectives of the second area are to understand the genetics of common and complex human diseases, such as diabetes, obesity, asthma, where evidence has been presented of the presence of genetic components to disease susceptibility. Of particular interest is to identify susceptibility genes predisposing individuals to non-insulin dependent diabetes mellitus.

Recent Representative Publications:

Deka, R, Majumder, P. P., Shriver, M. D., Stivers, D., Zhong, Y., Yu, L. M., Barrantes, R., Yin, S.-J., Miki, T., Hundrieser, J., Bunker, C. H., McGarvey, S. T., Sakallah, S., Ferrell, R. E., Chakraborty, R. (1996). Distribution and evolution of CTG repeats at the myotonin protein kinase gene in human populations, Genome Research. 6:142-154.

Kimmel, M., Chakraborty, R., Stivers, D. N., Deka, R. (1996). Dynamics of repeat polymorphisms under forward-backward mutation model: within- and between- population variability at microsatellite loci, Genetics. 143:549-555.

Deka, R., Jin, L., Shriver, M. D., Saha, N., Barrantes, R., Chakraborty, R., Ferrell, R. E. (1996.) Dispersion of human Y chromosome haplotypes based on five microsatellites in global populations, Genome Research. 6:1177-1184.

Chakraborty, R., Kimmel, M., Stivers, D. N., Davison, L. J., Deka, R. (1997). Relative mutation rates at di- , tri- , and tetranucletodie repeats, Proc Natl Acad Sci, USA. 94:1041-1046.

Shriver, M. D., Smith, M. W., Jin, L., Marcini, A., Akey, J. M., Deka, R., Ferrell, R. E. (1997). Ethnic affiliation estimation using population-specific DNA markers, Am J Hum Genet. 60:957-964.

Shriver, M. D., Jin, L., Ferrell, R. E., Deka, R. (1997). Microsatellite data support an early population expansion in Africa, Genome Research. 7:586-591.

Polanski, A., Chakraborty, R., Kimmel, M., Deka, R. (1997). Dynamic balance of segregation distortion and selection maintains normal allele sizes at the myotonic dystrophy locus, Math Biosci. 147:93-112.

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Dr. Kim N. Dietrich, Research Professor

Research in Progress:

Research in progress includes: I.) The investigation of the relationships among early exposure to lead, neuropsychological dysfunction, and juvenile delinquency in a prospective cohort study of 300 Cincinnati inner-city youth. This investigation is unique in that it is the only prospective longitudinal study of early lead exposure to extend follow-up to health outcomes measured in mid-adolescence. This cohort was recruited prenatally in the early 1980's and is the largest and most comprehensive study of its kind in the United States, 2.) The neurodevelopmental benefits of oral chelation therapy with dimercaptosuccinic acid (Succimer) in a multi-center randomized double-blind clinical trial. This investigation is focused on neuropsychological, neuromotor, social-emotional, and early academic outcomes in lead poisoned children (pretreatment PbB's 20-44 ug/dL) randomly assigned to either drug or placebo.

Recent Publications:

Dietrich, K. N., Berger, O. G., Succop, P. A. (1993). Lead exposure and the motor developmental status of 6 year old children in the Cincinnati Prospective Study, Pediatrics. 91: 301-307.

Dietrich, K. N., Berger, O. G., Succop, P. A., Bornshein, R. L., Hammond, P. A. (1993). The developmental consequences of low to moderate prenatal and postnatal lead exposure: Intellectual attainment in the Cincinnati Lead Study following school entry, Neurotoxicology and Teratology. 15: 37-44.

Bellinger, D. C., Dietrich, K. N. (1994). Low level lead exposure and cognitive function in children, Pediatric Annals. 23: 600-605.

Dietrich, K. N. ( 1998). Environmental toxicants and child development, in Neurodevelopmental Disorders: Contributions to a New Framework from the Cognitive Neurosciences, H. Tager-Flusberg, ed. Boston, MA: MIT Press.

Outreach Activities:

Recent invited consultations on matters pertaining to the effects of pollution on child health include the World Health Organization, National Institutes of Health, Health and Welfare Canada, United States Centers for Disease Control, Agency for Toxic Substances and Disease Registry, and United States Environmental Protection Agency.

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Dr. Peter S. Gartside, Associate Professor

Research Activity:

Funded research activity consists of a Biostatistical core within the program project "Transgenic Reporters", Dr. Peter Stambrook, principal investigator. Other funded research activity occurs by answering consultation requests from the U.C. Medical Center and Children's Hospital.

Unfunded research is conducted on NHANES datasets to determine which dietary and lifestyle factors influence the development of disease.

Pending research includes participation in grants originating in Children's Hospital through collaboration facilitated by consulting activities.

Recent Work:

Gartside PS, CJ Glueck . (1995) The Important Role of Modifiable Dietary and Behavioral Characteristics in the Causation and Prevention of Coronary Heart Disease Hospitalization and Mortality: The Prospective NHANES I Follow-up Study. Journal of the American College of Nutrition, Vol.14, No.1, 71-79.

Rice C, J Lockey, GK Lemasters, L Levin, P Gartside(1996). Identification Of Ranges In Airborne Fibre Concentrations In Refractory Ceramic Fibre Manufacture Related To Process Or Ventilation Modifications. Occupational Hygiene, vol. 3, pp. 85~9O.

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Dr. Grace Lemasters, Professor
Director of Epidemiology and Biostatistics Division

Research in Progress:

Dr. Grace Lemasters is an investigator for several on-going epidemiological occupational reproductive, pulmonary, and cytogenetics studies. Her current research program includes evaluating hormonal changes of young women in the military exposed to jet fuels. In addition, a study of caffeine consumption in early pregnancy, hormonal changes and pregnancy outcome is in progress. Also under investigation is a ten-year longitudinal industry-wide study of all U.S. workers manufacturing refractory ceramic fibers (a substitute for asbestos) and pulmonary changes. Her research explores exposure-effect relationships ill human populations and in particular exposures to mixtures such as solvents, fuels and fibers. She is also investigating research methodological issues including estimates of precision, reliability and validity. She is the Director, Division of Epidemiology & Biostatistics and Co-Director of the Genetic Epidemiology & Biostatistics Facilities and Service Core for the Center for Environmental Genetics. She is on the editorial board for the Journal of Occupational & Environmental Medicine and the Journal of Reproductive Toxicology.

Recent Publications:

Lemasters, G. K., Lockey, J. E., Levin, L. L., McKay, R. T., Rice, C. H., Horvath, E. P., Papes, D. M., Lu, J. W., and Feldman, D. J. An industry-wide pulmonary study of men and women manufacturing refractory ceramic fiber. (Accepted, AJE).

Lemasters, G. K., Atterbury, M. R., Booth-Jones, A. D., Bhattacharya, A., Ollila-Glenn, N., Forrester, C., and Forst, L. Prevalence of work-related musculoskeletal disorders in active union carpenters, Occupational and Environmental Medicine. (In press).

Booth-Jones, A. D., Lemasters, G. K., Succop. P., Atterbury, M., Bhattacharya, A. (1998). Reliability of Questionnaire Information Measuring Musculoskeletal Symptoms and Work Histories, AIHJ . 1:20-24.

Lockey, J. E., Levin, L. S., Lemasters, G. K., McKay, R. T., Rice, C. H., Hansen, K. R., Papes, D. M., Simpson, S. R., and Medvedovic. M. (1998). Longitudinal estimates of pulmonary function in refractory ceramic fiber manufacturing workers, Am J Respir Cri Care Med. 157:1-8.

Buchta, T. M., Rice, C. H., Lockey, J. E., Lemasters, G. K., and Gartside, P. S. (1998). A Comparative study of the National Institute for Occupational Safety and Health 7400 "A" and "B" counting rules using refractory ceramic fibers, Appl. Occup. Environ. Hyg. 13(1):58-61.

Albers, J. T., Li, Y., Lemasters, G., Sprague, S., Stinson, R., and Bhattacharya, A. (1997). An ergonomic education and evaluation program for apprentice carpenters, AJIM. 32(6):641-646.

Puhala, E., Lemasters, G., Smith, L., Talaska, G., Simpson, S., Joyce, J., Trinh, K., Lu, J. (1997). Jet fuel exposure in the United States Air Force, Applied Occupational and Environmental Hygiene. 12(9):606-610.

Hall, G., Rice, C., Lockey, J., Lemasters, G., and Gartside, P. (1997). A comparison of exposures to refractory ceramic fibres over multiple work shifts, Annals of Occupational Hygiene. 41(5):555-560.

Lemasters, G. K., Livingston, G. K., Lockey, J. E., Olsen, D. M., Shukla, R., New, G., Selevan, S., and Yiin, J. H. (1997). Genotoxic Changes After Low-Level Solvent and Fuel Exposure on Aircraft Maintenance Personnel, Mutagenesis. 12(4):237-243.

Smith, L. B., Bhattacharya, A., Lemasters, G., Succop, P., Puhala II, E., Medvedovic, M., and Joyce, J. (1997). Effect of chronic low level exposure to jet fuel on postural balance of U.S. Air Force personnel, JOEM. 39(7):623-632.

Bhattacharya, A., Greathouse, L., Warren, J., Li, Y., Dimov, M., Applegate, H., Stinson, R., and Lemasters, G. (1997). An ergonomic walkthrough observation of carpentry tasks: A pilot study, Applied Occupational anti Environmental Hygiene Journal. 12(4):278-287.

Borron, S. W., Forman, S. A., Lockey, J. E., Lemasters, G. K., and Yee, L. M. (1997). An early study of pulmonary asbestosis among manufacturing workers: Original data and reconstruction of the 1932 cohort, American Journal of Industrial Medicine. 31:324-334.

Scialli, A. R., Swan, S. H., Amler, R. W., Baird, D. D., Eskenazi, B., Gist, G., Hatch, M. C., Kesner, J. S., Lemasters, G. K., Marcus, M., Paul, M. E., Schulte, P., Taylor, Z., Wilcox, A. J., and Zahniser, C. (1997). Assessment of reproductive disorders and birth defects in communities near hazardous chemical sites. II. Female reproductive disorders, Reproductive Toxicology. 11(2/3):231-242.

Rice, C. H., Lockey, J. E., Lemasters, G. K., Levin, L. L., Staley, P., Hansen, K. R. (1997). Estimation of historical and current employee exposure to refractory ceramic fibers during manufacturing and related operations, Appl. Occup Environ Hyg. 12(1):54-61.

Lemasters, G. K. (1997). Occupational exposures and effects on male and female reproduction, in Environmental and Occupational Medicine, W. Rom, ed. Occupational Medicine, Little Brown and Co.

Lemasters, G. K. (1997). Maternal Occupational Exposures and Adverse Pregnancy Outcomes, in Encyclopaedia of Occupational Health and Safety, J. M. Stellman, ed. International Labor Office, Geneva.

Lemasters, G. K. (1997). Reproductive System, in Encyclopaedia of Occupational Health and Safety, J. M. Stellman, ed. International Labor Office, Geneva, vol. I., pg. 9.2.

Schrader, S., and Lemasters, G. K. (1997). Male Reproductive System, in Encyclopaedia of Occupational Health and Safety, J. M. Stellman, ed. International Labor Office, Geneva, vol. I, pg. 9.4-9.8.

Sonntag, D. M., Jederberg, W., Lemasters, G. K., Simpson, S., and Still, K. R. (1997). Military Personnel, in Occupational, Industrial, and Environmental Toxicolog, M. Greenberg, R. Hamilton, and S. Phillips, ed. CV Mosby.

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Dr. Linda Levin, Research Assistant Professor

Research in Progress:

Statistical analysis of epidemiological data relating an occupational exposure to pulmonary endpoints, including lung function, respiratory symptoms, and chest x-rays.

Statistical research of the effect of quantitative measurement error in an exposure variable on hypothesis testing.

Recent publications:

Lockey, J. E., Lemasters, G. K., Rice, C. H., Hansen, K., Levin, L.S., Shipley, R., Spitz, H., and Wiot, J. (1996). Refractory Ceramic Fiber Exposure and Pleural Plaques, American Journal of Respiratory Critical Care Medicine. 154;5:1405-1410.

Rice, C. H., Lockey, J. E., Lemasters, G. K., Levin, L. S., and Gartside, P. (1996). Identification of changes in airborne fibre concentrations in refractory ceramic fibre manufacture related to process or ventilation modifications, Occupational Hygiene. 3:85-90.

Lemasters, G. K., Lockey, J. E., Levin, L. S., McKay, R. T., Rice, C. H., Horvath, E. P., Papes, D. M., Lu, J. W., and Feldman, D. J. An industry-wide pulmonary study of men and women manufacturing refractory ceramic fiber, Am. Jr. Epi. (In press).

Lockey, J. E., Levin, L. S., Lemasters, G. K., McKay, R. T., Rice, C. H., Papes, D. M., Simpson, S. R., and Medvedovic, M. Longitudinal estimates of pulmonary function in refractory ceramic fiber manufacturing workers, AJRCC. (In press).

Awards:

Undergraduate degree-Honors in Mathematics, B. Maier College.

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Dr. Susan M. Pinney, Research Assistant Professor

Director of Medical Surveillance, Center for Occupational Health

Research Interests:

Dr. Pinney's research interests have focused on epidemiological studies of health effects of ionizing radiation, especially to workers at DOE sites and to residents living in proximity to DOE sites. She also has conducted studies of reproductive effects of occupational glycol ether exposure and pulmonary effects of superabsorbent polymer exposure in the paper products industry.

Recent Work:

Epidemiologist, Fernald Workers' Medical Monitoring Program and Fernald Residents' Medical Monitoring Program, Division of General Internal Medicine. Project Director: Robert Wones, MD.

Co-Principal Investigator, "Longitudinal Pulmonary Morbidity Study of Workers Exposed to Absorbent Gelling Material", Co-Principal Investigator with Douglas Linz, MD.

Co-Principal Investigator, "Prospective Cohort Study of Pregnancy Outcome Among Female Employees of the Semiconductor Industry", Co-Principal Investigator with Grace Lemasters, PhD.

Epidemiologist, 1) Work Histories - "Evaluating New Participatory Methods", 2) "Medical Surveillance Program for Construction Workers at Oak Ridge, Tennessee", and 3) "Exposure Histories for Construction Workers at Hanford, Washington", Principal Investigator: Eula Bingham, PhD.

Recent Citations:

Linz, D. L., Pinney, S. M., and Buncher, C. R. Cluster Analysis Applied to Building-Associated Illness, Journal of Occupational Medicine. (Submitted).

Pinney, S. M., and Lemasters, G. K. (1996). Spontaneous Abortions and Stillbirths in Semiconductor Employees, Occupational Hygiene. 2:387-401.

Radack, K., Martin, V., Wones, R., Buncher, R., Pinney, S., Mandell, K. (1996). Intercorrelations and sources of variability in three mutagenicity assays of somatic mutations: A population-based study, Mutation Research. 350:295-306.

Radack, K. L., Pinney, S. M., Livingston, G. K. (1995). Sources of variability in the human lymphocyte micronucleus assay: A population-based study, Environmental and Molecular Mutagenesis. 26:26-36.

Wones, R., Radack, K., Martin, V., Mandell, K., Pinney, S., Buncher, R. (1995). Do persons living near a uranium processing site have cytogenetic damage?, Mutation Research. 335:171-184.

Lemasters, G. K., and Pinney, S. M. (1990). Employment Status as a Confounder When Assessing Occupational Exposures and Spontaneous Abortion, Journal of Clinical Epidemiology. 42:975-98l.

Scientific or Academic Service:

National Committees:

• Member, Citizens Advisory Committee on Public Health Service Activities and Research at Department of Energy Sites: Fernald Health Effects Sub-Committee, CDC, DHHS, 1996-1999.
  
• Member, Hanford Medical Monitoring Work Group, ATSDR, 1996.

College of Medicine Committee:

• Member, Student Research Committee, 1995-1997.

Courses Taught:

1997-1998, 26-905-968, Special Topics - "Dilemmas in Epidemiology." Each class focuses on an actual dilemma on epidemiologic research. Integrated concepts in epidemiology are used to explore the facets of each problem and develop a method for study. Course methods include class discussion, internet-discussion groups, and resources on the WWW.

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Dr. Rakesh Shukla, Associate Professor

Research in Progress:

As an academic biostatistician in Environmental Health, Dr. Shukla's current research portfolio consists of:

• As Principal Investigator, involved in design & analysis issues of regulatory toxicology in general and the whole effluent toxicity tests in particular. He is focussing on improving the currently mandated guidelines for statistical evaluation of toxicity tests by studying the feasibility of alternative statistical approaches such as Bioequivalence approach.

• As chief statistician and coinvestigator, involved in two large population-based studies of Strokes. ( P.I.: J. Broderick) to investigate the environmental & genetic determinants of stroke, in particular with respect to their contribution in explaining both inter-racial as well as intra-racialdifferences between Caucasians and Americans of African origin.

• As a coinvestigator, involved in a study on the effectiveness of succimer therapy in preventing or reversing neuromotor deficits ( i.e., Postural Balance and Gait) associated with environmental lead exposure in children in a multi-center clinical trial currently being conducted. ( P.I. A.Bhattacharya).

• As a statistician, involved in the Facility & Service Core of the Center for Environmental Genetics ( P.I.:M. Anderson). Besides providing the routine statistical services to the center investigators and pilot projects, He is involved in design and Analysis of studies for conducting genome-wide scanning of stroke patients in an effort to identify gene(s) which render increased susceptibility to Stroke.

Recent Publications:

Lemasters, G. K., Shukla, R., Li, Y. D., Lockey, J. (1996). Balancing Cost and Precision in Exposure Assessment Studies, Journal of Occupational & Environmental Medicine. 38(l):39-45.

Livingston, G. K., Jensen, R. H.,Silberstein, E. B., Hinnefeld, J. D., Pratt, G., Bigbee, W. L., Langlois, R.G., Grant, S. G., Shukla, R. (1997). Radiobiological evaluation of immigrants from the vicinity of Chernobyl, Int.J. Radiat. Biol. 72(6):703-713.

Lemasters, G. K., Livingston, G. K., Lockey, J. E., Olsen,D. M., Shukla, R., New, G., Selevan, S. G., Yiin, J. (1997). Genotoxic changes after low-level solvent and fuel exposure on aircraft maintenance personnel, Mutagenesis. 12(4):237-243.

Bhattacharya, A., Smelser, D. T., Berger, O., Shukla, R., Medvedovic, M. The Effect of Succimer Therapy in Lead Intoxication Using Postural Balance As A Measure: A Case Study in A Nine Year Old Child, NeuroToxicology. (Accepted).

Welty, T. E., Privitera, M., and Shukla, R. Increased Seizure Frequency Associated with Felbamate Withdrawal in Adults, Archives of Neurology. (Accepted).

Broderick, J., Brott, T., Kothari, R., Miller, R., Khoury, J., Pancioli, A., Gebel, J.,Tomsick, T., Mills, D., Minneci, L., and Shukla, R. The Greater Cincinnati/Northern Kentucky Stroke Study: Preliminary first-ever an Total Incidence Rates of Stroke Among African-American, Stroke. (Accepted).

Outreach Activities:

Member, Lakota Advisory Commission, Lakota Board of Education;

Member, Board of Trustees for Local Radio Station;

Member, Internal Advisory Commission, Kumon Math and Reading, Mid-West, Chicago;

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Dr. Paul A. Succop, Associate Professor

Research in Progress:

Statistical and mathematical models for postural sway static & dynamic tasks.

Missing data imputation techniques.

Meta-analytic models for community lead study databases.

Structural equation methodologies.

Recent Publications:

Chiou, S. Y., Bhattacharya, A., Succop, P. A. (1996). Effect of workers' shoe wear on objective and subjective assessment of slipperiness, Am. Ind. Hyg. J. 57: 825-831.

Jiang, Q., Succop, P. A. (1996). A study of the specification of the log-log and log-additive models for the relationship between blood lead and environmental lead, J. Agric. Biolog. Environ. Statist. 1: 426-434.

Kuo, W., Bhattacharya, A., Succop, P. A., Linz, D. (1996). Postural stability assessment in sewer workers, J. Occup. Environ. Med. 38: 27-34.

Rosenthal, S. L., Lewis, L. M., Succop, P. A., Burklow, K. A., Biro, F. M. (1997). Adolescent girls' perceived prevalence of sexually transmitted diseases and condom use, Develop. Behav. Pediatrics. 18: 158-161.

Wang, B., Bhattacharya, A., Bagchee, A., Wang, W., Succop, P. A. (1997). Kinematic methods for quantifying loss of balance while negotiating a curved path on a slippery surface, J. Test. Evaluat. 25: 135-142.

Levin, L., and Succop, P. A. Comparison of bias and efficiency of three GEE estimators, 1996 Joint Statist. Meetings, Proceed. of the Sect. on Statist. and the Environ. (In press).

Luo, F.-Y., and Succop, P. A. Testing an improved method of missing data imputation, 1996 Joint Statist. Meetings, Proceed. of the Sect. on Statist. and the Environ. (In press).

Pei, H., and Succop, P. A. Anaconda longitudinal arsenic exposure study, 1996 Joint Statist. Meetings, Proceed. of the Sect. on Statist. and the Environ. (In press).

Succop, P. A. Defining Limits for data imputation: How much is too much?, 1996 Joint Statist. Meetings, Proceed. of the Sect. on Statist. and the Environ. (In press).

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