Today is Tuesday, Jan. 28, 2020

Department of Environmental Health

Risk Science Center (RSC)

Advancing the Science:  Chemical-Induced Asthma

This webinar series will discuss the advances being made with chemical-induced asthma and the role of clinical, toxicological, and epidemiological research in regulatory and hazard characterization approaches. 

Module 1: Current clinical perspectives in evaluating chemical induced asthma, or “What caused my asthma?” Jon Bernstein (University of Cincinnati)

A review of the clinical tests used to diagnose asthma.  This speaker will discuss symptom variability its effect on diagnostic ability

Module 2: The role of toxicology in asthma hazard assessment
David Basketter (DABMEB Consultancy Ltd)

A review of the in vivo, in vitro, and in silico models used for toxicological assessments of asthma and surrogate or related endpoints, specifically their utility and limitations.  This speaker will also discuss new methods, tests, and approaches for toxicological assessment.

Module 3:  Environmental contributions to asthma prevalence: Assessing the link between exposure and disease
Judy LaKind (LaKind Associates, Inc.)

A discussion of how the relationships between environmental exposures and asthma induction are addressed, specifically the endpoints and types of studies that are considered.  This speaker will address the limitations of current research methods and the difficulties associated with exposure estimation.

Module 4: Setting exposure limits for chemical allergens: Understanding the challenges
Scott Dotson (NIOSH)

This session would describe the types of information used to support chemical regulations and safety assessment decisions.

Module 5: Asthma-specific hazard characterization approaches: A novel approach to a complex problem - A
ndy Maier (University of Cincinnati)

Discussion of ongoing hazard characterization guidance developments specific to asthma that accounts for gaps in toxicological, epidemiological, and exposure information.


Sponsored by the American Cleaning Institute (ACI), in collaboration with the Risk Science Center, University of Cincinnati