Immune Diseases of the Skin

Diya F. Mutasim, M.D.

Dr. Diya Mutasim has special training and expertise in the diagnosis and treatment of patients with immune skin diseases such as lupus and related disorders as well as blistering disorders, for example, pemphigus and bullous pemphigoid. Dr. Mutasim has published extensively on this area and has given multiple national and international presentations on the topic.

For more information, refer to the following articles:

Mutasim DF, Takahashi Y, Labib RS, Anhalt GJ, Patel HP, Diaz LA: A pool of bullous pemphigoid antigen(s) is intracellular and associated with the basal cell cytoskeleton-hemidesmosome complex. J Invest Dermatol 84(1):47?53, 1985.

Mutasim DF, Anhalt GJ: Bullous diseases. In: Stein's Textbook of Internal Medicine, 2nd Edition, JH Stein (ed), Little, Brown and Company, Boston, MA, 1986. pp. 1368?1372.

Mutasim DF, Anhalt GJ, Diaz LA, Patel HP: Linear immunofluorescence staining of the cutaneous basement membrane zone produced by pemphigoid antibodies: The result of hemidesmosome staining. J Am Acad Dermatol 16:75?82, 1987.

Anhalt GJ, Patel HP, Jampel H, Jabs DA, Labib RS, Diaz LA, Mutasim DF: Bullous pemphigoid autoantibodies as markers of corneal epithelial hemidesmosomes. J Invest Ophth Vis Sci 28:903?907, 1987.

Mutasim DF, Morrison LH, Takahashi Y, Labib RS, Skouge J, Diaz LA, Anhalt GJ: Definition of bullous pemphigoid antibody binding to intracellular and extracellular antigen associated with hemidesmosomes. J Invest Dermatol 92:225?230, 1989.

Mutasim DF, Anhalt GJ: Bullous diseases. In: Stein's Textbook of Internal Medicine, 3rd Edition, JH Stein (ed), Little, Brown & Company, Boston, MA, 1990. pp. 1828-1832.

Anhalt GJ, Kim S, Stanley JR, Korman NJ, Jabs DA, Kory M, Izumi H, Ratrie H, Mutasim D, Ariss-Abdo L, Labib RS: Paraneoplastic pemphigus. An autoimmune mucocutaneous disease associated with neoplasia. N Engl J Med 323:1729-1735, 1990.

Mutasim DF, Diaz LA: The relevance of immunohistochemical techniques in the differentiation of subepidermal bullous diseases. Am J Dermatopathol 13:77-83, 1991.

Mutasim DF, Pelc N, Supapannachart N: Established methods in the investigation of bullous diseases. Dermatologic Clinics, 11(3):399-418, 1993.

Mutasim DF, Pelc N, Anhalt GF: Cicatricial pemphigoid. Dermatologic Clinics, 11(3):499-510, 1993.

Mutasim DF, Pelc N, Anhalt GF: Drug induced pemphigus. Dermatologic Clinics, 11(3):463-472, 1993.

Mutasim DF, Pelc N, Anhalt GJ: Paraneoplastic pemphigus. Dermatologic Clinics, 11(3):473-482, 1993.

Mutasim DF, Pelc N, Anhalt GF: Pemphigus vulgaris, pemphigus foliaceus and paraneoplastic pemphigus. Clin Dermatol, 11:113-117, 1993.

Supapannachart N, Mutasim DF: The distribution of IgA pemphigus antigen in human skin and the role of IgA anti-cell surface antibodies in the induction of intraepidermal acantholysis. Arch Dermatol, 129:605-608, 1993.

Mutasim DF: Bullous pemphigoid: review and update. Geriatr Dermatol, 1:62-71, 1993.

Fivenson DP, Breneman DL, Rosen GB, Hersh CG, Cardone JS, Mutasim DF: Nicotinamide and tetracycline therapy of bullous pemphigoid. Arch Dermatol, 130:753-758, 1994.

Mutasim DF, Anhalt GJ: Bullous diseases. Stein's Textbook of Internal Medicine, 4th edition. pp 2525-2530, 1994.

Mutasim DF: Management of bullous pemphigoid. Fitzpatrick's Journal of Clinical Dermatology, 3:33-39, 1995.

Mutasim DF: Bullous diseases. In: Conn's Current Therapy 1996, RE Rakel (ed), W.B. Saunders Company, Philadelphia, PA, 1996. pp. 806-812.

Mutasim DF: Bullous diseases in the elderly. J Geriatr Dermatol 4:32-34, 1996.

Mutasim DF, Cummings M: Linear IgA disease with clinical and immunopathological features of epidermolysis bullosa acquisita. J Pediatr Dermatol, 14:303-306, 1997.

Mutasim DF: Editorial: the accuracy of indirect immunofluorescence on salt-split skin in differentiating subepidermal bullous diseases. Arch Dermatol, 133:1158-1160, 1997.

Mutasim DF: Autoimmune Bullous Diseases: Diagnosis and Management. Dermatol Nurs, 11(1):15-23, 1999.

Mutasim DF: How to Diagnose & Manage Autoimmune Bullous Diseases. Skin & Aging, August 1999, pages 59-63.

Mutasim DF, Meiri G: Bazex syndrome mimicking a primary autoimmune bullous disorder. J Am Acad Dermatol, 40:822-825, 1999.

Mutasim DF: Subepidermal bullous diseases. Pathology of the Skin (2nd Edition), E Farmer and A Hood (ed), McGraw Hill, 2000, pages 249-273.

Mutasim D & Adams BB: Cicatricial pemphigoid diagnosed by the use of indirect immunofluorescence. J Cutan Med Surg 4(4):205-207, 2000.

Mutasim DF: Book Review: Atlas of Bullous Disease published by Churchill Livingstone, editor Robert E. Jordon. Arch Dermatol 137(7):976-977, 2001.

Mutasim DF & Adams BB: Immunofluorescence in dermatology. J Am Acad Dermatol 45:803-822, 2001.

Fueston J, Mutasim DF & Adams BB: Cicatricial pemphigoid induced phimosis. J Am Acad Dermatol 46:(S128-129, 2002.

Mutasim DF & Anhalt GJ: Bullous diseases in the elderly. In: Clinics in Geriatric Medicine, published by WB Saunders, Philadelphia, PA, Gilchrest BA (ed), 18(1):43-58, February 2002.

Eckman JA, Mutasim DF: Bullous systemic lupus erythematosus with milia and calcinosis. Cutis 40(1):31-34, 2002.

Mutasim DF: Treatment considerations while awaiting the ideal bullous pemphigoid trial. (Editorial). Arch Dermatol 138:404, 2002.

Mutasim DF: Laboratory diagnosis of autoimmune bullous diseases. G Ital Dermatol Venereol 137:383-93, 2002.

Mutasim DF. Autoimmune skin disorders. xPharm On-Line Pharmacology Reference and Database, www.xpharm.com . Elsevier Science, 2003.

Bilic M, Mutasim DF. Bullous pemphigoid. xPharm On-Line Pharmacology Reference and Database, www.xpharm.com . Elsevier Science, 2003.

Pipitone MA, Mutasim DF. Epidermolysis bullosa acquisita. xPharm On-Line Pharmacological Database, www.xpharm.com . Elsevier Science, 2003.

Sluzevich JC, Mutasim DF. Intraepithelial IgA bullous disease. xPharm On-Line Pharmacological Database, www.xpharm.com . Elsevier Science, 2003.

Tran TA, Mutasim DF. Linear IgA bullous disease. xPharm On-Line Pharmacological Database, www.xpharm.com . Elsevier Science, 2003.

Hawayek LH, Mutasim DF. Paraneoplastic pemphigus. xPharm On-Line Pharmacological Database, www.xpharm.com . Elsevier Science, 2003.

Hawayek LH, Mutasim DF. Pemphigus foliaceus. xPharm On-Line Pharmacological Database, www.xpharm.com . Elsevier Science, 2003.

Hawayek LH, Mutasim DF. Pemphigus vulgaris. xPharm On-Line Pharmacological Database, www.xpharm.com . Elsevier Science, 2003.

Manga P, Mutasim DF. Vitiligo. xPharm On-Line Pharmacological Database, www.xpharm.com . Elsevier Science, 2003.

Mutasim DF: Severe subacute cutaneous lupus erythematosus presenting with generalized erythroderma and bullae. J Am Acad Dermatol. 48:947-9, 2003.

Mutasim DF: Autoimmune bullous dermatoses in the elderly. Drugs & Aging 20(9), 664-681, 2003.

Mutasim D & Baumbach J: Bullous autoimmune estrogen dermatitis. J Am Acad Dermatol 49(1), 130-32, 2003.

Fein H, Sheth AP & Mutasim DF: Cutaneous arteritis presenting with hyperpigmented macules: Macular Arteritis. J Am Acad Dermatol 49(3): 519-522, 2003.

Mutasim DF: Management of autoimmune bullous diseases: Pharmacology & therapeutics. In press, J Am Acad Dermatol, 2004.