There is some risk associated with all treatments used for cutaneous lymphoma. In choosing the best treatment at any given point in the disease process, strong consideration must be given to ascertaining that the expected treatment benefit outweighs the potential for associated risk. Treatment recommendations will vary depending on unique patient characteristics, disease stage, patient preference and the prescribing physician’s choices. . Available here for review are general treatment guidelines for several therapeutic modalities. These guidelines may vary widely depending on individual patient circumstances.