EDUCATION

Doctorate of Science (1982), University of Massachusetts

Major: Veterinary and Animal Science

Master of Science (1979), University of Massachusetts

Major: Veterinary and Animal Science

Bachelor of Science (1976), University of Massachusetts

Major: Zoology (cum laude)

POSITIONS

2001 – Present Professor, University of Cincinnati College of Medicine, Department of Dermatology (Adjunct in Department of Cell Biology, Neurobiology & Anatomy and in the College of Pharmacy, Division of Pharmaceutics and Drug Delivery Systems)

2003 – Present Adjunc Professor, Union Institute & University, Division of Graduate Education, Cincinnati, OH

1991 – 2001 Associate Professor, University of Cincinnati College of Medicine, Department of Dermatology (Adjunct in Department of Cell Biology, Neurobiology & Anatomy)

1991 – 2001 Adjunct Associate Professor, University of Cincinnati College of Pharmacy, Division of Pharmaceutics and Drug Delivery Systems

1990 – Present Director of Dermatologic Research, University of Cincinnati College of Medicine, Department of Dermatology

1986 – 1991 Assistant Professor, University of Cincinnati College of Medicine, Department of Dermatology (Adjunct in Department of Cell Biology, Neurobiology & Anatomy)

1985 – 1986 Associate Research Scientist, Yale University School of Medicine, Department of Dermatology

1982 – 1985 Post-Doctoral Fellow, Yale University School of Medicine, Department of Dermatology

1976 – 1981 Graduate Research Assistant, University of Massachusetts, Department of Veterinary and Animal Science

PROFESSIONAL MEMBERSHIPS AND ORGANIZATION

American Association for the Advancement of Science (1978-present)

Sigma Xi (1980 - 1987)

American Society for Cell Biology (1982 - present)

International Federation of Pigment Cell Societies (1982 - present)

a) Program Committee Memb-XVIth IFPCS Meeting, Anaheim, CA, Oct. 1996

b) Council Member (2002-present)

c) Publications Committee (2002-present)

Pan American Society for Pigment Cell Research (1988 - present)

a) Council member: 1988 - 1992 (founding); 1994 - 1997

b) Member of Program Committee for 2nd PASPCR Meeting, 1989

c) Member of Bylaws Committee, 1989

d) Chairperson of Nominations Committee, 1989 - 1990

e) Chairperson of Program Committee for IVth PASPCR Meeting, 1992

f) Member of Nominations Committee, 1993

g) Member of Program Committee for Vth PASPCR Meeting, 1994

h) Acting Secretary/Treasurer, 1998

i) Secretary/Treasurer, 2001 - present

Society for Investigative Dermatology (1986 - present)

Electron Microscope Society of America (1988 - present)

a) Chairperson of Special Events Subcommittee of the Local Arrangement Committee for EMSA Meeting - 1993

Electron Microscope Society of the Ohio River Valley (1989 - present)

a) Treasurer (1992 - 1997)

Hair Research Society (1992 - Present)

Univera Inc. (Broomfield, CO) Scientific Advisory Board (1999 - present)

Neavus 2000 France-Europe (Cedex, France) Scientific Advisory Board (2000 – present)

Institute of Regenerative Medicine (National Taiwan University) Scientivic Advisory Board (2003 – present)

HONORS & AWARDS

Society of Cosmetic Chemists 2002 Literature Award

EDITORIAL ACTIVITIES

Editorial Boards

Pigment Cell Research American Editor (1992 - 1999)

Cutaneous Science (2003 – Present)

Ad Hoc Reviewer

Pigment Cell Research, American Journal of Pathology, Journal of Investigative Dermatology, CRC Press, Life Sciences, Photodermatology, Photoimmunology and Photomedicine, Journal of Cellular Physiology, Experimental Cell Research, Journal of Cell Science, Experimental and Molecular Pathology, Lancet, Journal of Lipid Research, American Journal of Medicine, Journal of Cell Biology, Archives of Dermatology, Nature Genetics

GRANT REVIEW BOARDS

Alberta Heritage Foundation for Medical Research - 1990, 1991, 1992

National Science Foundation - 1987, 1988, 1992, 1993

Arizona Research Commission - 1987

National Institutes of Health (Ad Hoc in GMA1) - 1993, 1996, 1998, 1999, 2000, 2001

INVITED LECTURES

November, 2003, 17^th Annual Meeting of the Japanese Society for Pigment Cell Research, Tokyo, Japan, Invited Keynote Lecturer. “Melanocyte defects in Hermansky-Pudlak Syndrome”.

November, 2003, Indiana University School of Medicine, Indianapolis, IN., Midwest Dermatology Residency Program: Invited Speaker, “The Melanocyte and Melanogenesis”.

July, 2003, 2^nd National Vitiligo Foundation Patient Support Conference, Trumbull, CT, Invited Presenter, “The Smyth Chicken: An avain model for vitiligo”.

May, 2003, University of Cincinnati College of Medicine, Cincinnati, OH., Department: Cell Biology, Neurobiology, & Anatomy, “Hermansky-Pudlak Syndrome: A disease(s) resulting from impaired cellular trafficking”.

April, 2003, Procter & Gamble-Asia, Taipei, Taiwan, Invited Speaker at Press Conference, “Blocking of Melanosome Transfer”

March, 2003, Procter & Gamble, Hair Care Division, Cincinnati, OH., Invited Speaker, “Cellular and molecular regulation of melanosome synthesis”.

Nov, 2002, 28^th Annual Meeting of the Chinese Dermatological Society, Taipei, Taiwan, Invited Lecturer, “Cellular mechanisms governing melanosome transfer to and distribution in keratinocytes”.

October, 2002, Avon Inc., Cutaneous Research Division, Nutley, New Jersey, Invited Speaker, “New, novel approaches to skin lightening”.

October, 2002, Pfizer Global Research & Development, Anaderm Research Division, Ann Arbor, MI. Invited Speaker, “Research Frontiers in Cutaneous Pigmentation”.

Sept, 2002, XVIIIth International Pigment Cell Conference. Egmond aan Zee, The Netherlands, Invited Presenter in Satellite Meeting on Hyperpigmentation and Hypopigmenting Agents, “Review of arbutin and derivatives”.

July, 2002, 1^st National Vitiligo Foundation Patient Support Conference, Cincinnati, OH, Invited Presenter, “Current Advances in Cell Biological Research on Vitiligo”.

June, 2002, 1^st Asian Conference on Photobiology, Hyogo, Japan, Invited Seminar Presenter, “Recent advances in regulation of melanogenesis”.

June, 2002, 1^st Asian Conference on Photobiology, Hyogo, Japan, Special Keynote Lecturer, “Regulation of melanosome transfer to and distribution in keratinocytes”.

June, 2002, KAO Corporation, Tochigi, Japan, Department: Biological Sciences Lagoratories, Invited Lecturer, Current mechanisms regulating tyrosinase activity and melanosome transfer to keratinocytes of the skin”.

June, 2002, KAO Corporation, Tochigi, Japan, Department: Biological Sciences Lagoratories, Invited Lecturer, “Development of deoxyarbutin as a tyrosinase inhibitor”.

May, 2002, National Taiwan University, Taipei, Taiwan, Department: Dermatology, Invited Lecturer, “Vitiligo and its induction by phenolic agents”.

May, 2002, Chinese Dermatology Society Annual Spring Meeting, Taipei, Taiwan, Invited Keynote Speaker, “Melanocyte and Melanization”.

November, 2001, Indiana University School of Medicine, Indianapolis, IN., Midwest Dermatology Residency Program: Invited Speaker, “The Melanocyte and Melanogenesis”.

July, 2001, National Taiwan University, Taipei, Taiwan, Department: Dermatology, Invited Lecturer, “The interaction between the melanocyte and the keratinocyte regulating skin pigmentation”.

July, 2001, 2^nd Annual Meeting of the Japanese Society for Photoaging Research, Kobe, Japan. Special Keynote Lecturer, “Regulation of the Transfer of Melanosomes to and their Subsequent Distribution in Keratinocytes”.

April, 2001, Thailand Dermatology Conference, Bangkok, Thailand. Invited Keynote Speaker, “Inhibition of Melanosome Transfer in the Epidermis”.

March, 2001, Asia Dermatologist Panel Meeting, Bangkok, Thailand. Invited Keynote Speaker/Presider, “Effect of Niacinamide on Melanosome Transfer [Surface Glycoproteins Involvement and the Distribution of Melanosomes in Keratinocytes]”.

March 2001, Beauty Editor Briefing at Chiva-Som, Hua Hin, Thailand. Presentor, “Control of Skin Pigmentation by Niacinamide”

March 2001, Procter & Gamble Asia, Skin Care Division, Kobe, Japan, Invited Speaker, “Surface Glycoproteins Involved in Melanosome Transfer and the Distribution of Melanosomes in Keratinocytes”.

November, 2000, Indiana University School of Medicine, Indianapolis, IN., Midwest Dermatology Residency Program: Invited Speaker, “The Melanocyte and Melanogenesis”.

July, 2000. National Institute of Child Health and Development (NICHD), Hermansky-Pudlak Syndrome Conference, Bethesda, MD, Invited Speaker, “Analysis of Melanocyte Dysfunction in Hermansky-Pudlak Syndrome”.

June, 2000. 9^th PanAmerican Society for Pigment Cell Research Conference, College Station, TX., Invited Speaker, "Dissecting Translocation Signals Via the Hermansky-Pudlak Syndrome".

June, 2000. National Institute for Occupational Safety and Health (NIOSH) Dermal Interest Group (DIG) annual meeting, Cincinnati, OH, Invited Presenter in the Research Symposium, "Destruction of Cutaneous Melanocytes by 4-Tertiary Butyl Phenol: A Model for Contact/Occupational Vitiligo".

May, 2000. 61^st Annual Meeting of the Society for Investigative Research, Chicago, IL. Invited Presenter/Discussant at the Joint Session of the SID and the PanAmerican Society for Pigment Cell Research, "History of the Identification of Members of the Tyrosinase Gene Family".

March, 2000. Annual LAM Foundation Patient Conference, Cincinnati, OH, Invited Presenter in Scientific Session, "Melanogenesis and Its Relationship to Lymphoangiomyomatosis".

February, 2000. Annual Hermansky-Pudlak Syndrome Patient Conference, Uniondale, NY, Invited Presenter, "Pathophysiology of Melanocytes Cultured from Patients with Hermansky-Pudlak Syndrome".

December, 1999, Annual Meeting of the Society of Cosmetic Chemists, New York City, NY., Invited Presenter at the melanin Symposium, "Vitiligo".

November, 1999, National Defense Medical Center, Taipei,Taiwan, Department: Biology & Anatomy, "The Development of Cutaneous Melanogenesis and Associated Hypopigmentary Disorders".

November, 1999, The Catholic University of Korea, Seoul, Korea, Department: Dermatology, "The Pathophysiology of Vitiligo".

October, 1999, XVIIth International Pigment Cell Conference, Nagoya, Japan, Invited Presenter for Workshop on Apoptosis, "Morphologic Manifestations of Apoptosis and Vitiligo".

July, 1999, American Academy of Dermatology, New York City, Invited Presenter for Basic Science of Dermatology Session, "Melanocyte Biology".

November, 1998, Second Intercontinental Meeting of the Hair Research Societies, Washington, D.C.,

Invited Workshop Organizer, “Overview of Melanogenesis”.

October, 1998, Avon Inc. Nutley, New Jersey, Cutaneous Research Division, Invited Speaker, “Mechanisms of Melanosome Transfer in the Skin”.

September, 1998, Indiana University School of Medicine, Indianapolis, IN., Midwest Dermatology Residency Program: Invited Speaker, “The Melanocyte and Melanogenesis”.

August, 1998, 8^th PanAmerican Society for Pigment Cell Research Conference, Snowmass, CO.,

Invited Presenter for Workshop on Vitiligo, "Cellular Pathophysiology of Vitiligo".

October, 1997, Indiana University School of Medicine, Indianapolis, IN., Midwest Dermatology Residency Program: Invited Speaker, “The Melanocyte and Melanogenesis”.

April, 1997, National Institute of Child Health and Development (NICHD), Bethesda, MD., Hermansky-Pudlak Syndrome Conference: Invited Speaker, “Ultrastructural and Biochemical Findings in HPS Melanocytes”.

November, 1996, XVth International Pigment Cell Conference, Anaheim, California, Invited Keynote Speaker, “Melanogenesis and Pigmentary Disorders”.

March, 1996, Washington University School of Medicine, St. Louis, MO., Department: Cell Biology and Physiology, “Pigmentation of Hair and Skin”.

March, 1996, The Wistar Institute, Philadelphia, PA., Department: Molecular and Cellular Biology, “Tyrosinase Related Protein-1: On Its Role in Melanognensis, Albinism and Vitiligo” .

March, 1995, Department of Pediatrics/Human Genetics, University of Cincinnati/Children's Hospital, "Albinism".

October, 1994, Division of Pharmacology & Medicinal Chemistry, University of Cincinnati College of Pharmacy, "Cell Biology of the Melanocyte and Associated Diseases".

November, 1993, R.W. Johnson/Ortho Pharmaceuticals, New Jersey. Skin Biology Research Center, "The Role of Tyrosinase Related Protein-1 in Amelanosis".

October, 1993, University of Cincinnati College of Medicine, Department: Pediatrics/Human Genetics, "Molecular Basis of Pigmentation: What Color are your Genes?".

March, 1993, New York University School of Medicine, New York City, NY., Department: Dermatology, "On The Pathophysiology of Vitiligo and Albinism: To B or not to B".

November, 1991, University of Cincinnati/Children's Hospital, Department: Pediatrics/Human Genetics, "Current Research Advances in the Pathophysiology of Albinism".

September, 1991, Christ Hospital, Cincinnati, Ohio, Department: Pediatrics, "Phenotypic, Genetic and Biological Heterogeneity in Albino Patients".

November, 1990, XIVth International Pigment Cell Conference, Kobe, Japan, Invited Symposium Speaker, "Inherent Cellular Defects in Vitiligo".

June, 1988, 1st Pan American Pigment Cell Society Conference, Minneapolis, MN, Invited Symposium Speaker, "Cytological Evidence for Post-Translational Control of Melanogenesis".

January, 1988, University of Cincinnati College of Pharmacy, Cosmetic Science Program. "Electron Microscopy of the Skin".

October, 1987, University of Cincinnati College of Medicine, Department: Anatomy and Cell Biology, "The Melanocyte - Its Role in Vitiligo and Albinism".

October, 1986, XIIIth International Pigment Cell Conference , Tuscon, Az., Invited Symposium Speaker, "Animal Models of Acquired Pigmentary Disorders".

April, 1986, Texas A&M University, College Station, TX., Department: Biology, "The Role of Melanocyte Dysfunction in Vitiligo".

January, 1986, University of Arizona, Tuscon, AZ., Department: Anatomy, "Avian Models for Vitiligo and Albinism: Melanocyte Dysfunction in Vivo and in Vitro".

March, 1985, Sloan-Kettering Medical Institute, New York Cint, NY., Department: Dermatology, "Avian Albinism and Vitiligo".

September, 1983, XIIth International Pigment Cell Conference - Giessen, Germany, Invited Symposium Speaker, "Melanogenesis and Autophagocytosis of Melanin of Delayed Amelanotic (DAM) Chickens".

PUBLICATIONS

A] BOOKS

Nordlund JJ, RE Boissy, VJ Hearing, RA King and J-P Ortonne (eds). 1998. The Pigmentary System: Physiology and Pathophysiology. Oxford University Press, New York, NY.

B] BOOK CHAPTERS & REVIEWS

Boissy RE. 2003. Melanosome transfer to and translocation in the keratinocyte. Exp Derm. 13 (Suppl. 2):1-8.

Huizing M, RE Boissy, WA Gahl. 2002. Hermansky-Pudlak Syndrome: Vesicle formation from yeast to man. Pigment Cell Res 15:405-419.

Boissy RE and L Minwalla. 2002. Regulation of melanosome transfer to and distribution in keratinocytes. J Photosci. 9:213-216.

Huang CL, JJ Nordlund, and RE Boissy. 2002. Vitiligo: A manifestation of apoptosis? Am J Clin Dermatol. 3:301-308.

Sarangarajan R and RE Boissy. 2001. Tyrp1 and Oculocutaneous Albinism Type 3. Pigment Cell Res. 14:437-444.

Nordlund JJ and RE Boissy. 2001. The Biology of Melanocytes. In: The Biology of Skin, DT Woodley and RK Freindel (eds), Parthenon Publishing, Pearl River, NY. pp. 113-131.

Boissy RE. 2001. Chapter 44: Vitiligo. In: The Molecular Pathology of Autoimmunity (2^nd Ed), AN Theofilopoulos and CA Bona (eds), Gordon and Breach/Harwood Academic Publishers, Langhorne, PA. pp. 773-780.

Boissy RE and SB Hoath. 2000. Congenital Pattern Leukoderma. In: James WD, Elston D. (Chief Eds);. EMedicine Dermatology. St. Petersburg: eMedicine Corporation. (http://www.emedicine.com/derm/index.shtml).

Boissy RE and JJ Nordlund. 2000. Albinism. In: James WD, Elston D. (Chief Eds);. EMedicine Dermatology. St. Petersburg: eMedicine Corporation. (http://www.emedicine.com/derm/index.shtml).

Boissy RE. 2000. Chapter 5: Histology of Vitiliginous Skin. In: Vitiligo. S-K Hann and JJ Nordlund (eds), Blackwell Science, Oxford, UK. pp. 23-34.

Boissy RE. 2000. Chapter 15: The Intrinsic (Genetic) Theory for the Cause of Vitiligo. In: Vitiligo. S-K Hann and JJ Nordlund (eds), Blackwell Science, Oxford, UK. pp. 123-128.

Lamoreux ML and RE Boissy. 2000. Chapter 33: Animal Models. In: Vitiligo. S-K Hann and JJ Nordlund (eds), Blackwell Science, Oxford, UK. pp. 281-297.

Introne W, RE Boissy and WA Gahl. 1999. Clinical, Molecular, and Cell Biological Aspects of Chediak-Higashi Syndrome. Molecular Genetics and Metabolism 68:283-303.

Wood JM, K Jimbow, RE Boissy, A Slominski, P Plonka, J Slawinski, J Wortsman and J Tosk. 1999. What’s the use of generating melanin? Exp Dermatol. 8:153-164.

Boissy RE, F Yang, IC Le Poole and YL Boissy. 1999. Morpologic Manifestations of Apoptosis. In: Symposium on Vitiligo: A Manifestation of Apoptosis? Hann S-K and JJ Nordlund (Eds.). For 17^th International Pigment Cell Conference, October 30, 1999. Nagoya, Japan. pp 9-12.

Boissy RE. 1998. Chapter 4: Extracutaneous melanocytes. In: The Pigmentary System: Physiology and Pathophysiology, JJ Nordlund, RE Boissy, VJ Hearing, RA King, J-P Ortonne (eds), Oxford University Press, New York, NY. pp. 59-73.

Carden SM, RE Boissy, P Schoettaker and WV Good. 1998. Albinism: Review of the condition. Br J Opthtamol 82:189-195.

Boissy RE and JJ Nordlund. 1997. The molecular basis of congenital hypopigmentary disorders in humans – A review. Pigment Cell Res 10:12-24.

Le Poole IC and RE Boissy. 1997 Vitiligo. In: Seminars in Cutaneous Medicine and Surgery, Vol. 16(1), KA Arndt, PE Le Boit, JK Robinson, BU Wintroub (eds), WB Saunders Company, Philadelphia, PA. pp. 1-13.

Boissy RE and JJ Nordlund. 1995. Biology of melanocytes. In: Cutaneous Medicine and Surgery: An Integrated Program in Dermatology, KA Arndt, PE LeBoit, JK Robinson, BU Wintroub (eds), WB Saunders Co., Philadelphia, PA. pp. 1203-1209.

Boissy RE and JJ Nordlund. 1995. Vitiligo. In: Cutaneous Medicine and Surgery: An Integrated Program in Dermatology, KA Arndt, PE LeBoit, JK Robinson, BU Wintroub (eds), WB Saunders Co., Philadelphia, PA. pp. 1210-1218.

Nordlund JJ, ZA Abdel-Malek, RE Boissy and LA Rheins. 1989. Pigment Cell Biology: An Historical Review. J Invest Dermatol 92:53S-60S.

Boissy RE. 1988. The Melanocyte: Its structure, function and subpopulations in the skin, eyes and hair. In: 1988 Dermatologic Clinics, JJ Nordlund (ed), WB Saunders Co., Philadelphia, PA. pp. 161-173.

Boissy RE and ML Lamoreux. 1988. Animal models of an acquired pigmentary disorder - vitiligo. In: Proceedings of the XIII International Pigment Cell Conference, Tucson, Arizona, 1986, J Bagnara (ed), Alan R. Liss, Inc., New York, NY. pp. 207-218.

C] PEER REVIEWED JOURNALS

Greatens A, T Hakozaki, S Schwemberger, G Babcock, D Bissett, RR Wickett, and RE Boissy. 2003. Effective melanosome transfer by niacinamide and lectins is reversible. J Invest Dermatol (in prep).

Thong H-Y, S-H Jee, C-C Sun and RE Boissy. 2003. The pattern and mechanism of melanosome distribution in keratinocytes of human skin as one determining factor of skin colour. Br J Dermatol 149:1-8.

Kitzmiller WJ, RA Stanton, RR Wickett, G Tolia, RE Boissy and MO Visscher. 2003. Non-invasive skin measures after CO₂ and erbium laser resurfacing” Aesthetic Surgery J 23:20-27.

Rizvi TA, Y Huang, A Sidami, R Atit, DA Largaespada, RE Boissy and N Ratner. 2002. A novel cytokine pathway suppresses glial cell melanogenesis after injury to adult nerve. J Neurosci 22:9831-9840.

Hakozaki T, L Minwalla, J Zhaung, M Chhoa, A Matsubara, K Miyamoto, A Greatens, GG Hillebrand, DL Bissett and RE Boissy. 2002. The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer. Br J Dermatol 147:20-31.

Abdalkhani A, R Sellers, J Gent, H Wulitich, S Childress, B Stein, RE Boissy, JJ Wysolmerski and J Foley. 2002. Nipple connective tissue and its development: insights from the K14-PTHrP mouse. Mech Dev 115:63-77.

Le Poole IC, R Sarangarajan, Y Zhao, LS Stennett, P Sheth, T Miki and RE Boissy. 2001. A novel gene associated with vitiligo. Pigment Cell Res 14:475-484.

Sarangarajan R, A Budev, Y Zhao, WA Gahl and RE Boissy. 2001. Abnormal translocation of tyrosinase and tyrosinase-related protein 1 in cutaneous melanocytes of Hermansky-Pudlak syndrome and in melanoma cells transfected with anti-sense HPS1 cDNA. J Invest Dermatol 117:641-646.

Minwalla L, Y Zhao, IC Le Poole, RR Wickett and RE Boissy. 2001. Keratinocytes play a role in regulating distribution patterns of recipient melanosomes in vitro. J Invest Dermatol 117:341-347.

Huizing M, R Sarangarajan, E Strovel, Y Zhao, WA Ghal and RE Boissy. 2001. AP-3-dependent vesicles carry tyrosinase, but not TRP-1 in cultured human melanocytes. Mol Biol Cell 12:2075-2085.

Minwalla L, Y Zhao, J Cornelius, G Babcock, RR Wickett, IC Le Poole, and RE Boissy. 2001. Inhibition of melanosome transfer from melanocytes to keratinocytes by lectins and neoglycoproteins in an in vitro model system. Pigment Cell Res 14:185-194.

Manga P, RE Boissy, S Pifko-Hirst, B-K Zhao and SJ Orlow. 2001. Mislocalization of melanosomal proteins in melanocytes from mice with oculocutaneous albinism type 2. Exp Eye Res 72:695-710.

Sarangarajan R, H Shumaker, M Soleimanai, C Le Poole and RE Boissy. 2001. Molecular and functional characterization of sodium hydrogen exchanger in skin as well as cultured keratinocytes and melanocytes. Biochim Biophys Acta 1511:181-192.

Pickens WL, RR Warner, RE Boissy and SB Hoath. 2000. Characterization of human vernix: Water content, morphology, and elemental analysis. J Invest Dermatol 115:875-881.

Sarangarajan R, Y Zhao, G Babcock, J Cornelus, L Lamoreux and RE Boissy. 2000. Mutant alleles at the tyrosinase related protein-1 (TRP-1) locus affect the proliferation of mouse melanocytes in culture. Pigment Cell Res. 13:337-344.

Le Poole IC, RE Boissy, R Sarangarajan, J Chen, JJ Forristal, P. Sheth, W Westerhof, G Babcock, PK Das and CB Saelinger. 2000. PIG3V, an immortalized human vitiligo melanocytes cell line, expresses dilated endoplasmic reticulum. In Vitro Cell Dev Biol Anim 36:309-319.

Yang F, R Sarangarajan, IC Le Poole, EE Medrano and RE Boissy. 2000. The cytotoxicity and apoptosis induced by 4-tertiary butylphenol in human melanocytes is independent of tyrosinase activity. J Invest Dermatol 114:157-164.

Yang F, Z Abdel-Malek and RE Boissy. 1999. Effects of commonly used mitogens on the cytotoxicity of 4-tertiary butylphenol to human melanocytes. In Vitro Cell Dev Biol Anim 35:566-570.

Le Poole, IC, F Yang, TL Brown, J Cornelius, G Babcock, PK Das and RE Boissy. 1999. Altered gene expression in melanocytes exposed to 4-tertiary butyl phenol (4-TBP): Upregulation of the A_2b adenosine receptor. J Invest Dermatol 113:725-731.

Yang F and RE Boissy. 1999. Effects of 4-tertiary butylphenol on the tyrosinase activity in human melanocytes. Pigment Cell Res 12:237-245.

Tripathi RK, DJ Flanders, TL Young, WS Oetting, A Ramaiah, RA King RE Boissy and JJ Nordlund. 1999. Microphthalmia associated transcription factor (MITF) locus lacks linkage to human vitiligo and osteroptrosis; An evaluation. Pigment Cell Res 12:187-192.

Boissy RE, Y Zhao and WA Gahl. 1998. Altered protein localization in melanocytes from Hermansky-Pudlak Syndrome: Support for the role of the HPS gene product in intracellular trafficking. Lab Invest 78:1037-1048.

Collawn SS, RE Boissy and LO Vasconez. 1998. Skin ultrastructure following CO2 laser resurfacing. Plast Reconstr Surg 102:509-515.

Boissy RE, C Sakai, H Zhao, T Kobayashi and VJ Hearing. 1998. Human tyrosinase related protein-1 (TRP-1) does not function as a DHICA oxidase activity in contrast to murine TRP-1. Exp Derm 7:198-204.

Collawn SS, RE Boissy, M Gamboa and LO Vasconez. 1998. Ultrastructure study of the skin following facial chemical peels and the effect of moisturization on wound healing. Plas Reconstr Surg 101:1374-1379.

Cieszka K, HZ Hill, P Xin, M Azure, GJ Hill, MF Meyenhofer, RE Boissy and DL Mitchell. 1997. Survival of Cloudman mouse melanoma cells after irradiation by solar wavelengths of light. Pigment Cell Res 10:193-200.

Hill HZ, GJ Hill, K Cieszka, PM Plonka, DL Mitchell, MF Meyenhofer, P Xin and RE Boissy. 1997. Comparative action spectrum from ultraviolet light killing of mouse melanocytes from different genetic coat color backgrounds. Photochem Photobiol 65:983-989.

Nagle DL, MA Karim, EM Woolf, L Holmgren, P Bork, DJ Misumi, SH McGrail, BJ Dussault Jr., RE Boissy, GM Duyk, RA Spritz and KJ Moore. 1996. Mutations in the human orthologue of the mouse beige gene in patients with Chediak-Higashi syndrome. Nature Genet 14:307-311.

Boissy RE, H Zhao, WS Oetting, LM Austin, SC Wildenberg, YL Boissy, Y Zhao, RA sturm, VJ Hearing, RA King and JJ Nordlund. 1996. Mutation in and lack of expression of tyrosinase related protein-1 (TRP-1) in melanocytes from an individual with tyrosinase-positive oculocutaneous albinism: A new subtype of albinism classified as OCA3. Am J Hum Genet 58:1145-1156.

Donatien PD, SL Diment, RE Boissy and SJ Orlow. 1996. Melanosomal and lysosomal alterations in murine melanocytes following transfection with the v-ras^Ha oncogene. Int J Cancer 66:557-563.

Zhao H, D Eling, EE Medrano and RE Boissy. 1996. Retroviral infection with human tyrosinase related protein-1 (TRP-1) cDNA upregulates tyrosinase activity and melanin synthesis in a TRP-1 deficient melanoma cell line. J Invest Dermatol 106:744-752.

Boissy RE, ML Lamoreux. 1995. In vivo and in vitro morphological analysis of melanocytes homozygous for the mi^sp allele of the murine microphthalmia locus. Pigment Cell Res 8:294-301.

Wang H, ES Grood, W Ip and RE Boissy. 1995. Cellular orientation response to cyclic deformed substrate: Mathematical modeling and experimental studies. J Biomechanics 28:1543-1552.

Beerman F, SJ Orlow, RE Boissy, A Schmidt, YL Boissy and ML Lamoreux. 1995. Misrouting of tyrosinase with a truncated cytoplasmic tail as a result of the murine platinum (C^P) mutation. Exp Eye Res 61:599-607.

Farooqui JZ, EE Medrano, RE Boissy, RE Tigelaar and JJ Nordlund. 1995. Thy-1+ dendritic cells express truncated form of POMC mRNA. Exptl Dermatol 4:297-301.

Austin LM and RE Boissy. 1995. Tyrosinase related protein-1 is recognized by autoantibodies from vitiliginous Smyth chickens. Am J Pathol 146:1529-1541.

Zhao H, EE Medrano, JJ Nordlund and RE Boissy. 1994. Nonradioactive Northern analysis of melanoma total RNA using the S&S psoralen/biotin labeling and detection system. Sequences 44:1-3.

Zhao H and RE Boissy. 1994. Distinguishing between the catalytic potential and apparent expression of tyrosinase activities. Am J Med Sci 308:322-330.

Zhao H, Y Zhao, JJ Nordlund and RE Boissy. 1994. Human TRP-1 has tyrosine hydroxylase but not DOPA oxidase activity. Pigment Cell Res 7:131-140.

Zhao H, YL Boissy, Z Abdel-Malek, RA King, JJ Nordlund and RE Boissy. 1994. On the analysis of the pathophysiology of Chediak-Higashi syndrome: Defects expressed by cultured melanocytes. Lab Invest 71:25-34.

Medrano EE, F Yang, R Boissy, J Farooqui, V Shah, K Matsumoto, JJ Nordlund and H-Y Park. 1994. Terminal differentiation and senescence in the human melanocyte: repression of tyrosine-phosphorylation of the extracellular signal regulated kinase 2 (ERK2) selectively defines the two phenotypes. Mol Biol Cell 5:497-509.

Abdel-Malek Z, V Swope, C Collins, R Boissy, H Zhao and J Nordlund. 1993. Contribution of melanogenic proteins to the heterogeneous pigmentation of human melanocytes. J Cell Sci 106:1323-1331.

Farooqui JZ, BW Auclair, E Robb, E Sarkisian, C Cooper, JW Alexander, G Warden, RE Boissy and JJ Nordlund. 1993. Histological, biochemical and ultrastructural studies on hyperpigmented human xenografts. Pigment Cell Res 6:226-233.

Orlow SJ, BK Zhou, RE Boissy and S Pifko-Hirst. 1993. Identification of a mammalian melanosomal matrix glycoprotein. J Invest Dermatol 101:141-144.

Searle EA, LM Austin, YL Boissy, H Zhao, JJ Nordlund and RE Boissy. 1993. Smyth chicken melanocyte autoantibodies: Cross-species reactivity in vivo binding and plasma membrane binding of the antiserum. Pigment Cell Res 6:145-157.

Boissy RE, YL Boissy, JM Krakowsky, ML Lamoreux, JB Lingrel and JJ Nordlund. 1993. Ocular pathology in mice with a transgenic insertion at the microphthalmia locus. J Submicroscop Cytol Pathol 25:319-332.

Medrano EE, JZ Farooqui, RE Boissy, YL Boissy, B Akadiri and JJ Nordlund. 1993. Chronic growth-stimulation of human adult melanocytes by inflammatory mediators in vitro: Implications for nevi formation and initial steps in melanocyte oncogenesis. Proc Natl Acad Sci USA 90:1790-1794.

Zhou B-Z, RE Boissy, S, Pifko-Hirst, DJ Moran and SJ Orlow. 1993. Lysosome-associated membrane protein-1 (LAMP-1) is the melanocyte vesicular membrane glycoprotein, Band II. J Invest Dermatol 100:110-114.

Orlow SJ, RE Boissy, DJ Moran and S Pifko-Hirst. 1993. Subcellular distribution of tyrosinase and tyrosinase-related protein-1: Implications for melanosomal biogenesis. J Invest Dermatol 100:55-64.

Krakowsky JM, RE Boissy, JC Neumann and JB Lingrel. 1993. A DNA insertional mutation results in microphthalmia in transgenic mice. Transgenic Res 2:14-20.

Lamoreux ML, RE Boissy, JE Womack and JJ Nordlund. 1992. The vit gene maps to the Mi (Microphthalmia) locus of the laboratory mouse. J Hered 83:435-439.

Austin LM, RE Boissy, BS Jacobson and JR Smyth Jr. 1992. The detection of melanocyte autoantibodies in the Smyth chicken model for vitiligo. Clin Immunol Immunopath 64:112-120.

Chetty BV, RE Boissy, GD Warden and JJ Nordlund. 1992. Basement membrane and fibroblast aberration in blisters at the donor, graft and spontaneously healed sites in burn patients. Arch Dermatol Res 128:181-186.

Boissy RE, Y-Y Liu, EE Medrano and JJ Nordlund. 1991. Structural aberration of the rough endoplasmic reticulum and melanosome compartmentalization in long-term cultures of melanocytes from vitiligo patients. J Invest Dermatol 97:395-404.

Boissy RE, KE Beato and JJ Nordlund. 1991. Dilated rough endoplasmic reticulum and premature cell death in melanocytes cultured from the vitiligo mouse. Am J Pathol 138:1511-1525.

Orlow SJ, AK Chakraborty, RE Boissy and JM Pawelek. 1990. Inhibition of induced melanogenesis in Cloudman melanoma cells by four phenotypic modifiers. Exp Cell Res 191:209-218.

Hoath SB, MM Donnelly and RE Boissy. 1990. Sensory transduction and the mammalian epidermis. Biosensors Bioelec 5:351-366.

Boissy RE, LS Trinkle and JJ Nordlund. 1990. Neural tube derived melanocyte subsets undergo commitment to their distinct lineages in culture. Cell Diff Dev 30:129-145.

Hoath SB, WL Pickens, SF Sells and RE Boissy. 1990. Epidermal development in the growth retarded fetal rat. J Dev Physiol 13:41-50.

Boissy RE, L Trinkle and JJ Nordlund. 1989. Separation of pigmented and amelanotic melanocytes and the concomitant evaluation of endogenous peroxide content using flow cytometry. Cytometry 10:779-787.

Nordlund JJ, S Amornsiripanitch, LA Rheins, ZA Abdel-Malek, RE Boissy and M Bell. 1988. The role of the melanocyte in epidermal inflammatory/immune responses. Pigment Cell Res Suppl 1:101-112.

Abdel-Malek ZA, VB Swope, LS Trinkle, EN Ferroni, RE Boissy and JJ Nordlund. 1988. Alterations of Cloudman melanoma cell cycle by prostaglandins E1 and E2 using a bromodeoxyuridine method of DNA analysis. J Cell Physiol 136:247-256.

Boissy RE, S Gecks, JR Smyth Jr and JJ Nordlund. 1988. Ocular pathology in the minimally depigmented subline of the vitiliginous Smyth chicken. Pigment Cell Res 5:303Ä314.

Lamoreux ML, L Gerrity and RE Boissy. 1987. Vitiligo in several animal species. Comp Pathol Bull 19:3-5.

Boissy RE, GE Moellmann and R Halaban. 1987. Tyrosinase and acid phosphatase activities in melanocytes from avian albinos. J Invest Dermatol 88:292-300.

Boissy RE, GE Moellmann and AB Lerner. 1987. Morphology of melanocytes in hair bulbs and eyes of vitiligo mice. Am J Pathol 127:380-388.

Lerner AB, T Shiohara, RE Boissy, KA Jacobson, ML Lamoreux and GE Moellmann. 1986. A possible mouse model for vitiligo. J Invest Dermatol 87:299-304.

Boissy RE, GE Moellmann, AA Trainer, JR Smyth Jr and AB Lerner. 1986. Delayed-amelanotic (DAM-Smyth) chicken: Melanocyte dysfunction in vivo and in vitro. J Invest Dermatol 86:149-156.

Boissy RE and R Halaban. 1985. Establishment of proliferative pure cultures of pigmented chicken melanocytes from neural tubes. J Invest Dermatol 84:158-161.

Boissy RE, GE Moellmann and JR Smyth Jr. 1985. Melanogenesis and autophagocytosis of melanin with developing feather melanocytes of delayed-amelanotic (DAM) chickens. In: Pigment Cell 7: Proceedings of XIIth International Pigment Cell Conference, Giessen, Germany, 1983. Editors: Bagnara J, Klaus SN, Paule E, Schartl M, University of Tokyo Press, Tokyo, Japan. pp. 731-739.

Smyth JR Jr, ML Boyle III, SJ Lamont and RE Boissy. 1985. Spontaneous remelanization of feathers in adult amelanotic DAM line chickens. In: Pigment Cell 7: Proceedings of the XIIth International Pigment Cell Conference, Giessen, Germany, 1983. Editors: Bagnara J, Klaus SN, Paule E, Schartl M, University of Tokyo Press, Tokyo, Japan. pp. 741-747.

Boissy RE, SJ Lamont and JR Smyth Jr. 1984. Persistence of abnormal melanocytes in immunosuppressed chickens of the autoimmune "DAM" line. Cell Tissue Res 235:663-668.

Boissy RE, JR Smyth Jr and KV Fite. 1983. Progressive cytologic changes during the development of delayed feather amelanosis and associated choroidal defects in the DAM chicken line. A vitiligo model. Am J Pathol 111:197-212.

Fite KV, N Montgomery, T Whitney, R Boissy and JR Smyth Jr. 1982. Inherited retinal degeneration and ocular amelanosis in the domestic chicken (Gallus domesticus). Current Eye Res 2:109-115.

Lamont SJ, RE Boissy and JR Smyth Jr. 1982. Humoral immune response and expression of spontaneous postnatal amelanosis in the DAM line chickens. Immunol Comm 11:121-127.

Smyth JR Jr, RE Boissy and KV Fite. 1981. The DAM chicken: A model for spontaneous postnatal cutaneous and ocular amelanosis. J Hered 72:150-156.

Smyth JR Jr, RE Boissy, KV Fite and DM Albert. 1981. Blindness associated with postnatal amelanosis in the chicken. Invest Opthal Vis Sci 20:799-803.