Dermatology Clinical Research Center

Division of Clinical Research

Department of Dermatology, University of Cincinnati College of Medicine

CLINICAL TRIALS (Partial Listing)

CONDITION STUDIED	PHASE	NUMBER CONTRACTED	NUMBER ENROLLED	TYPE of DRUG
Acne vulgaris	III	21	21	Topical retinoid
Acne vulgaris	III	30	40^a	Topical anti-microbial
Acne vulgaris	III	30	30	Topical anti-microbial
Acne vulgaris	III	80	83^a	Combination topical antibiotic
Acne vulgaris	III	45	45	Combination topical medication
Acne vulgaris	III	40	40	Topical anti-inflammatory
Acne vulgaris	II	32	32	Topical retinoid
Acne vulgaris	II	54	54	Topical retinoid
Acne vulgaris	III	15	15	Topical retinoid/anti-inflammatory
Acne vulgaris	III	48	48	Topical medication
Acne vulgaris	III	32	64^a	Topical antibiotic
Acne vulgaris	III	50	58^a	Topical antibiotic
Atopic dermatitis	III	30	30	Topical anti-pruritic
Atopic dermatitis	III	30	40^a	Topical anti-pruritic
Atopic dermatitis	IV	25	28^a	Topical anti-pruritic
Atopic dermatitis	III	24	24	Antihistamine
Atopic dermatitis	IV	--	9^c	Topical corticosteroid
Atopic dermatitis	IV	11	17^a	Topical corticosteroid
Atopic dermatitis	II	21	21	Topical anti-inflammatory
Atopic dermatitis	II	15	7^b	Topical anti-inflammatory
Atopic dermatitis	IV	50	50	Soap
Atopic dermatitis	III	15	16^c	Topical anti-inflammatory
Atopic dermatitis	III	16	24	Combination topical anti-inflammatory
Atopic dermatitis	III	10	ongoing	Topical corticosteroid
Atopic dermatitis - pediatric	IV	10	24^a	Topical anti-pruritic
Atopic dermatitis - pediatric	IV	34	34	Topical corticosteroid
Atopic dermatitis - pediatric	II	10	11^a	Topical anti-inflammatory
Atopic dermatitis - pediatric	II	5	10^a	Topical anti-inflammatory
Atopic dermatitis - pediatric	III	15	19^a	Topical anti-inflammatory
Condyloma accuminata	III	--	9	Podophyllin resin
Contact dermatitis	IV	40	40	Topical antibacterial corticosteroid
Cutaneous fragility	IV	20	20	Skin protectant
Cutaneous fragility	IV	20	20	Skin protectant
Cutaneous tanning	I	48	48	Tanning inducer
Cutaneous tanning	I	25	25	Tanning inducer
Cutaneous tanning	I	26	26	Tanning inducer
Dandruff	III	100	150^a	Medicated shampoo
Dandruff	III	60	60	Medicated shampoo
Dermatitis	II	28	23^b	Topical nonsteroidal anti-inflammatory
Female androgenic alopecia	III	30	38^a	Topical vasodilator
Folliculitis	III	18	12^b	Topical antibiotic
Gonorrhea	III	--	22^c	Parenteral antibiotic
Hair growth	N/A	50	123^a	None
Hemodialysis associated pruritus	IV	--	20	Topical substance-P inhibitor
Herpes zoster	III	10	7	Oral anti-viral agent
Hyperkeratotic dermatoses	III	40	40	Topical corticosteroid/keratolytic agent
Hyperpigmentation	II	--	29	Bleaching agent
Ichthyosis vulgaris	III	20	20	Topical moisturizer
Infected dermatoses	III	50	106^a	Topical antibiotic
Infected skin ulcers	III	50	62^a	Topical antibiotic
Male androgenic alopecia	III	40	60^a	Topical vasodilator
Mycosis fungoides	II	15	33^a	Topical retinoid
Mycosis fungoides	IV	--	10	Total skin irradiation ± systemic chemotherapy
Mycosis fungoides	IV	--	6	Nucleoside analogue + interferon
Mycosis fungoides	N/A	--	10	Topical chemotherapeutic agent
Mycosis fungoides	II/III	--	8	Oral retinoid
Nasal staph aureus carriage	III	50	65^a	Topical antibiotic
Onychomycosis	III	30	50^a	Topical antifungal
Onychomycosis	III	40	40	Topical antifungal
Onychomycosis	III	30	45^a	Oral antifungal
Onychomycosis	III	20	25^a	Oral antifungal
Onychomycosis	II	30	50^a	Topical antifungal
Onychomycosis	III	12	13^a	Oral antifungal
Onychomycosis	III	27	52^a	Topical antifungal
Photoaging	IV	40	40	Topical retinoid
Pruritus in the elderly	III	28	28	Antihistamine
Pruritus secondary to dermatitis	III	40	75^a	Topical anti-pruritic
Psoriasis	III	30	30	Topical anti-psoriatic
Psoriasis	III	30	30	Topical tni-psoriatic
Psoriasis	III	40	45^a	Topical corticosteroid/keratolytic agent
Psoriasis	III	48	52	Topical retinoid
Psoriasis	III	24	24	Topical corticosteroid
Psoriasis	II	20	20	Topical anti-psoriatic
Psoriasis	I/II	10	12^a	Topical anti-inflammatory
Psoriasis	IV	50	60^a	Topical corticosteroid
Psoriasis	IV	40	40	Topical corticosteroid
Psoriasis	III	30	30	Topical anti-psoriatic
Psoriasis	III	30	30	Topical retinoid
Psoriasis	II	40	40	Topical anti-inflammatory
Psoriasis	III	30	36^a	Topical anti-inflammatory
Psoriasis	II	8	9^a	Parenteral cytotoxin
Psoriasis	II	6	15^a	Parenteral fusion protein
Psoriasis	II	5	⁹	Parenteral monoclonal antibody
Psoriasis	III	15	¹⁶	Topical substance P inhibitor
Psoriasis/Atopic dermatitis	IV	10	20^a	Topical corticosteroid
Psoriasis - Scalp	III	40	40	Topical corticosteroid
Psoriasis - Scalp	III	13	18	Topical corticosteroid
Rosacea	III	24	24	Topical anti-inflammatory
Rosacea	IV	36	36	Topical anti-inflammatory
Rosacea	II	20	27^a	Topical antibiotic
Rosacea	III	25	⁵⁰	Topical anti-inflammatory
Skin irritancy	I	48	48	Topical antihistamine
Skin irritancy	I	29	29	Topical antihistamine
Skin / Skin structure infection	IV	20	20	Oral antibiotic
Skin / Soft tissue infection	III	30	59^a	Oral antibiotic
Skin / Soft tissue infection	III	10	10	Oral antibiotic
Skin / Soft tissue infection	III	8	9	Oral antifungal
Photoaging	I	4	4	Sun protectant
Sweat gland activity	--	100	125^a	None
Tinea pedis	III	45	60^a	Topical antifungal/Steroid
Tinea pedis	III	60	54^b	Topical antifungal/Steroid
Tinea pedis	IV	25	30^a	Topical antifungal
Tinea pedis	III	21	74^a	Topical antifungal/Steroid
Tinea pedis	III	40	40	Topical antifungal
Tinea pedis	IV	30	30	Topical antifungal/Steroid combination
Tinea pedis	III	36	78^a	Topical antifungal
Tinea pedis	II	16	24^a	Topical antifungal
Tinea pedis	III	48	60^a	Topical antifungal
Tinea pedis	III	25	42^a	Topical antifungal
Tinea pedis	III	20	24^a	Topical antifungal
Tinea pedis	III	40	⁶⁰	Topicl antifungal
Tinea pedis	III	40	⁶⁰	Topical antifungal
Tinea pedis	III	15	²⁴	Topical antifungal
Tinea pedis	III	12	²⁷	Topical antifungal
Tinea pedis - Pediatric	IV	6	10^a	Topical antifungal
Tinea pedis - Preventative	IV	20	22^a	Topical antifungal
Tissue / Blood concentration	III	40	36^b	Oral antibiotic
Ultrastructural cutaneous changes	IV	3	3	Moisturizers
Urticaria	III	18	24^a	Antihistamine
Urticaria	III	18	18	Antihistamine
Urticaria	III	18	19^a	Antihistamine
Xerosis	I	6	6	Neurotransmitter depleter

Key:

a = Sponsor requested additional patients due to low enrollment at other sites

b = Sponsor decision for early discontinuation at all sites

c = Study previously initiated at other sites; this site added late due to low enrollment at other sites

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